المؤلفون: Inne H.M. Borel Rinkes, Klaas M. Govaert, Maarten W. Nijkamp, Frederik J.H. Hoogwater, Ernst J.A. Steller, Connie R. Jimenez, Andre Verheem, Winan J. van Houdt, Benjamin L. Emmink, Hans Clevers, Onno Kranenburg, Robert G.J. Vries

المساهمون: Medical oncology laboratory, CCA - Innovative therapy, Hubrecht Institute for Developmental Biology and Stem Cell Research

المصدر: Gastroenterology, 141(1), 269-278. W.B. Saunders Ltd
Emmink, B L, Van Houdt, W J, Vries, R G, Hoogwater, F J H, Govaert, K M, Verheem, A, Nijkamp, M W, Steller, E J A, Jimenez, C R, Clevers, H, Rinkes, I H M B & Kranenburg, O 2011, ' Differentiated Human Colorectal Cancer Cells Protect Tumor-Initiating Cells From Irinotecan ', Gastroenterology, vol. 141, no. 1, pp. 269-278 . https://doi.org/10.1053/j.gastro.2011.03.052

مصطلحات موضوعية: Oncology, medicine.medical_specialty, ATP Binding Cassette Transporter, Subfamily B, Time Factors, Colorectal cancer, Cellular differentiation, Blotting, Western, Mice, Nude, Cyclosporins, Biology, Adenocarcinoma, Irinotecan, Mice, Cancer stem cell, Internal medicine, Spheroids, Cellular, medicine, Biomarkers, Tumor, Tumor Cells, Cultured, Animals, Humans, ATP Binding Cassette Transporter, Subfamily B, Member 1, Mice, Inbred BALB C, Hepatology, Dose-Response Relationship, Drug, Liver Neoplasms, Gastroenterology, Cell Differentiation, Aldehyde Dehydrogenase, medicine.disease, Flow Cytometry, Antineoplastic Agents, Phytogenic, Xenograft Model Antitumor Assays, Tumor Burden, Tumor progression, Drug Resistance, Neoplasm, Colonic Neoplasms, Cancer research, Neoplastic Stem Cells, Camptothecin, Stem cell, Topoisomerase I Inhibitors, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98767f3d5122965ef453426c0fc726d7
https://hdl.handle.net/20.500.11755/a0d0766d-1263-45fa-a1c4-7fda3151823c

المؤلفون: Dae Hyuk Moon, Dong-Hyung Cho, Seung-Mi Kim, Se Jin Jang, Min-Hee Ryu, Tae Won Kim, Yong Sang Hong, Jung Shin Lee, Jin Cheon Kim, KH Jung, Young-Soon Na

المصدر: Cancer Chemotherapy and Pharmacology. 68:389-398

مصطلحات موضوعية: Cancer Research, Colorectal cancer, medicine.drug_class, medicine.medical_treatment, Mice, Nude, Antineoplastic Agents, Apoptosis, Pharmacology, Hydroxamic Acids, Irinotecan, Toxicology, Mice, Random Allocation, In vivo, Antineoplastic Combined Chemotherapy Protocols, medicine, Animals, Humans, Prodrugs, Whole Body Imaging, Pharmacology (medical), Viability assay, Thymidine kinase 1, neoplasms, Cell Proliferation, Sulfonamides, Chemotherapy, Chemistry, Histone deacetylase inhibitor, Drug Synergism, HCT116 Cells, medicine.disease, Xenograft Model Antitumor Assays, digestive system diseases, Tumor Burden, Histone Deacetylase Inhibitors, Oncology, Colonic Neoplasms, Camptothecin, Female, Topoisomerase I Inhibitors, HT29 Cells, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f9c4ce67b8e1a5cd4946bef8f4a93bc
https://doi.org/10.1007/s00280-010-1495-6

المؤلفون: Wataru Yamamoto, Fumio Nagashima, Ken-ichi Fujita, Takashi Hirose, Hiroo Ishida, Yuko Akiyama, Yuichi Ando, Yasutsuna Sasaki, Kazuhiro Araki, Shigehira Saji, Keisuke Miwa, Keishi Yamashita, Masaru Narabayashi, Wataru Ichikawa, Yu Sunakawa, Toshimichi Miya, Keiko Mizuno, Kaori Kawara

المصدر: Cancer Chemotherapy and Pharmacology. 68:279-284

مصطلحات موضوعية: Adult, Oncology, Heterozygote, Cancer Research, medicine.medical_specialty, medicine.medical_treatment, Leucovorin, Irinotecan, Toxicology, digestive system, Advanced colorectal cancer, Japan, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, Genotype, Humans, Medicine, Prodrugs, Pharmacology (medical), Glucuronosyltransferase, Alleles, Biotransformation, Genetic Association Studies, Survival analysis, Aged, Neoplasm Staging, Retrospective Studies, Pharmacology, Chemotherapy, Polymorphism, Genetic, business.industry, Retrospective cohort study, Middle Aged, Survival Analysis, Toxicity, FOLFIRI, Camptothecin, Female, Fluorouracil, Topoisomerase I Inhibitors, Colorectal Neoplasms, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbd2d576ca687d277c71ada8efa1a04d
https://doi.org/10.1007/s00280-010-1485-8

المؤلفون: Byoung Chul Cho, Hye Jin Choi, Youngjoo Lee, Moo Suk Park, Joo Hang Kim, Minkyu Jung, Jaeheon Jeong, Joon Chang, Sang Joon Shin, Joohyuk Sohn, Se Hyun Kim, Se Kyu Kim

المصدر: Lung Cancer. 70:77-81

مصطلحات موضوعية: Adult, Male, Pulmonary and Respiratory Medicine, Cancer Research, medicine.medical_specialty, Lung Neoplasms, Organoplatinum Compounds, medicine.medical_treatment, Salvage therapy, Neutropenia, Irinotecan, Gastroenterology, Small-cell carcinoma, Disease-Free Survival, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Carcinoma, Small Cell, Lung cancer, Aged, Salvage Therapy, Chemotherapy, business.industry, Cancer, Middle Aged, medicine.disease, Surgery, Clinical trial, Oncology, Camptothecin, Female, Topoisomerase I Inhibitors, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bf34f64676f8c96ee5c95271964ecbc
https://doi.org/10.1016/j.lungcan.2010.01.006

المؤلفون: Mithran S. Goonewardene, Tony C.A. Phan, Joanne Ooi

المصدر: Journal of Periodontal Research. 45:331-336

مصطلحات موضوعية: Keratinocytes, Male, Adolescent, Cell Survival, Periodontal Ligament, Immunoblotting, Gingiva, Apoptosis, Bone and Bones, Cell Line, Phosphatidylinositol 3-Kinases, Gene expression, In Situ Nick-End Labeling, medicine, Antigens, Ly, Humans, Periodontal fiber, Enzyme Inhibitors, Child, Fibroblast, Cells, Cultured, Phosphoinositide-3 Kinase Inhibitors, Messenger RNA, Reverse Transcriptase Polymerase Chain Reaction, business.industry, Kinase, Mouth Mucosa, Anatomy, Fibroblasts, Urokinase-Type Plasminogen Activator, Androstadienes, medicine.anatomical_structure, Cell culture, Cancer research, Periodontics, Camptothecin, Female, Topoisomerase I Inhibitors, Wortmannin, business, Plasminogen activator

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6c1b3c065ad5f32609b8541bc42da02
https://doi.org/10.1111/j.1600-0765.2009.01240.x

المؤلفون: Jun-ichiro Kuroda, Yohei Saito, Masahiro Yasunaga, Yoshikatsu Koga, Yasuhiro Matsumura

المصدر: European Journal of Cancer. 46:650-658

مصطلحات موضوعية: Antimetabolites, Antineoplastic, Cancer Research, medicine.medical_specialty, Pancreatic disease, Mice, Nude, SN-38, Pharmacology, Irinotecan, Deoxycytidine, Mice, chemistry.chemical_compound, Drug Delivery Systems, Pancreatic tumor, Internal medicine, Pancreatic cancer, medicine, Irinotecan Hydrochloride, Animals, Humans, Enzyme Inhibitors, neoplasms, Micelles, Mice, Inbred BALB C, Prodrug, medicine.disease, Antineoplastic Agents, Phytogenic, Xenograft Model Antitumor Assays, Gemcitabine, Pancreatic Neoplasms, Endocrinology, Oncology, chemistry, Drug delivery, Camptothecin, Female, Topoisomerase I Inhibitors, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b983445acbc1c258b314c459796cb3b2
https://doi.org/10.1016/j.ejca.2009.11.014

المؤلفون: Miroslav Červinka, Emil Rudolf, Kamil Rudolf

المصدر: Neoplasma. :316-324

مصطلحات موضوعية: Cancer Research, MAP Kinase Signaling System, p38 mitogen-activated protein kinases, Immunoblotting, Apoptosis, Antineoplastic Combined Chemotherapy Protocols, Tumor Cells, Cultured, medicine, Humans, Topoisomerase II Inhibitors, Cytotoxicity, Melanoma, Etoposide, Cell Proliferation, Membrane Potential, Mitochondrial, biology, Chemistry, Topoisomerase, JNK Mitogen-Activated Protein Kinases, Wild type, Oxidative Stress, DNA Topoisomerases, Type II, DNA Topoisomerases, Type I, Oncology, Cell culture, Caspases, Mutation, biology.protein, Cancer research, Camptothecin, Topoisomerase I Inhibitors, Tumor Suppressor Protein p53, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3eace7a7aa18ac361b016fb31181c974
https://doi.org/10.4149/neo_2010_04_316

المؤلفون: A. C. McDonald, Robert S. Brown

المصدر: British Journal of Cancer

مصطلحات موضوعية: Cancer Research, endocrine system diseases, Apoptosis, Camptothecin Analogue, Irinotecan, Tumor Cells, Cultured, medicine, Humans, heterocyclic compounds, Clonogenic assay, Tumor Stem Cell Assay, Ovarian Neoplasms, biology, Topoisomerase, Cell Cycle, Cell cycle, Flow Cytometry, Genes, p53, Antineoplastic Agents, Phytogenic, DNA Topoisomerases, Type I, Oncology, Drug Resistance, Neoplasm, Cell culture, Cancer research, biology.protein, Camptothecin, Female, Topotecan, Topoisomerase I Inhibitors, Tumor Suppressor Protein p53, Research Article, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42f2f5a106c396e293411b5ac6762b59
https://doi.org/10.1038/bjc.1998.571

المؤلفون: Alessandro Desideri, Elena Di Gennaro, Silvia Castelli, Alfredo Budillon, Francesca Bruzzese, Monia Rocco

المصدر: Molecular Cancer Therapeutics. 8:3075-3087

مصطلحات موضوعية: Cancer Research, Lung Neoplasms, DNA damage, medicine.drug_class, Type I, Apoptosis, Pharmacology, Hydroxamic Acids, Histone Deacetylases, Cell Line, Topoisomerase I Inhibitors, DNA Damage, Humans, Cell Line, Tumor, Reactive Oxygen Species, Camptothecin, Small Cell Lung Carcinoma, DNA Topoisomerases, Type I, Antineoplastic Combined Chemotherapy Protocols, Topotecan, Drug Synergism, Cell Cycle, medicine, Vorinostat, Tumor, biology, Settore BIO/11, Topoisomerase, Histone deacetylase inhibitor, Oncology, biology.protein, DNA fragmentation, DNA Topoisomerases, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da20d97384855366d8f31d45467af5f0
https://doi.org/10.1158/1535-7163.mct-09-0254

المؤلفون: David Goldstein, Guy van Hazel, David H. Price, Monica A. Rossleigh, Nick Pavlakis, Michael Tapner, Ian N. Olver, Gregory M. Briggs, Geoffrey D. Bower, D. James Taylor, Jacob George

المساهمون: van Hazel, Guy A, Pavlakis, Nick, Goldstein, David, Olver, Ian N, Tapner, Michael J, Price, David, Bower, Geoffrey D, Briggs, Gregory M, Rossleigh, Monica A, Taylor, D James, George, Jacob

المصدر: Journal of Clinical Oncology. 27:4089-4095

مصطلحات موضوعية: Male, Cancer Research, Time Factors, Colorectal cancer, medicine.medical_treatment, Brachytherapy, Gastroenterology, Enzyme Inhibitors, Infusions, Intravenous, irinotecan, Liver Neoplasms, Middle Aged, Microspheres, Treatment Outcome, Oncology, Chemotherapy, Adjuvant, Fluorouracil, Female, Colorectal Neoplasms, medicine.drug, Adult, Antimetabolites, Antineoplastic, medicine.medical_specialty, Maximum Tolerated Dose, medicine.drug_class, colorectal cancer, Irinotecan, Antimetabolite, Disease-Free Survival, Drug Administration Schedule, Internal medicine, Yttrium Isotopes, medicine, Humans, Aged, Chemotherapy, business.industry, Australia, Cancer, medicine.disease, Surgery, fluorouracil chemotherapy, Radiation therapy, Drug Resistance, Neoplasm, Concomitant, randomized controlled trial, Camptothecin, Radiotherapy, Adjuvant, Radiopharmaceuticals, Topoisomerase I Inhibitors, business, liver metastases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5dc76b7cdda549e333b7d51198adaad
https://doi.org/10.1200/jco.2008.20.8116