المؤلفون: Ukhyun Jo, Yasuhisa Murai, Keli K. Agama, Yilun Sun, Liton Kumar Saha, Xi Yang, Yasuhiro Arakawa, Sophia Gayle, Kelli Jones, Vishwas Paralkar, Ranjini K. Sundaram, Jinny Van Doorn, Juan C. Vasquez, Ranjit S. Bindra, Woo Suk Choi, Yves Pommier

المصدر: Mol Cancer Ther

مصطلحات موضوعية: Cancer Research, Nuclear Proteins, Ataxia Telangiectasia Mutated Proteins, DNA, Article, Mice, Oncology, DNA Topoisomerases, Type I, Neoplasms, Animals, Humans, Camptothecin, Topoisomerase I Inhibitors, Protein Kinase Inhibitors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6466f0700aba495f0651048d49ff2da
https://europepmc.org/articles/PMC9256811/

المؤلفون: Florence Gattacceca, Alexandre Evrard, Marc Ychou, Laure Deyme, Dominique Barbolosi, Nicole Tubiana-Mathieu, Litaty Mbatchi

المساهمون: Méthodes computationnelles pour la prise en charge thérapeutique en oncologie : Optimisation des stratégies par modélisation mécaniste et statistique (COMPO), Inria Sophia Antipolis - Méditerranée (CRISAM), Institut National de Recherche en Informatique et en Automatique (Inria)-Institut National de Recherche en Informatique et en Automatique (Inria)-Centre de Recherche en Cancérologie de Marseille (CRCM), Aix Marseille Université (AMU)-Institut Paoli-Calmettes, Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Aix Marseille Université (AMU)-Institut Paoli-Calmettes, Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Hôpital Universitaire Carémeau [Nîmes] (CHU Nîmes), Centre Hospitalier Universitaire de Nîmes (CHU Nîmes), CHU Limoges, Institut de Recherche en Cancérologie de Montpellier (IRCM - U1194 Inserm - UM), CRLCC Val d'Aurelle - Paul Lamarque-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), GATTACCECA, Florence

المصدر: Cancer Chemotherapy and Pharmacology
Cancer Chemotherapy and Pharmacology, 2021, 88 (2), pp.247-258. ⟨10.1007/s00280-021-04255-9⟩
Cancer Chemotherapy and Pharmacology, Springer Verlag, 2021, 88 (2), pp.247-258. ⟨10.1007/s00280-021-04255-9⟩

مصطلحات موضوعية: Male, 0301 basic medicine, Oncology, Cancer Research, FOLFIRINOX, Leucovorin, Toxicology, 0302 clinical medicine, CPT-11, Antineoplastic Combined Chemotherapy Protocols, Pharmacology (medical), Population pharmacokinetics, ComputingMilieux_MISCELLANEOUS, education.field_of_study, [SDV.SP]Life Sciences [q-bio]/Pharmaceutical sciences, [SDV.SP] Life Sciences [q-bio]/Pharmaceutical sciences, Oxaliplatin, 030220 oncology & carcinogenesis, FOLFIRI, Female, Fluorouracil, Folfirinox Regimen, Colorectal Neoplasms, medicine.drug, medicine.medical_specialty, Population, [SDV.CAN]Life Sciences [q-bio]/Cancer, Context (language use), Irinotecan, Nonlinear mixed effect modelling, 03 medical and health sciences, [SDV.CAN] Life Sciences [q-bio]/Cancer, Pharmacokinetics, Internal medicine, medicine, Humans, education, Pharmacology, business.industry, [SDV.MHEP.HEG]Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology, stomatognathic diseases, 030104 developmental biology, [SDV.SP.PHARMA]Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology, Camptothecin, Topoisomerase I Inhibitors, business

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::104f89d9adaa70ea34468906b96ef3b6
https://doi.org/10.1007/s00280-021-04255-9

المؤلفون: Patrick M. Boland, Christos Fountzilas, Marwan Fakih, Mateusz Opyrchal, Jennifer R. Diamond, Bradley Corr, Wen Wee Ma, Michelle Redman, Wing-Kai Chan, Hui Wang, Doug Kramer, Rudolf Kwan, David Cutler, Jay Zhi, Antonio Jimeno

المصدر: Cancer chemotherapy and pharmacology. 90(2)

مصطلحات موضوعية: Pharmacology, Mesylates, Cancer Research, Oncology, Maximum Tolerated Dose, Neoplasms, Antineoplastic Combined Chemotherapy Protocols, Humans, Pharmacology (medical), Camptothecin, Topoisomerase I Inhibitors, Toxicology, Irinotecan

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31b49acc47391fc7d89a6b5e2a902b88
https://pubmed.ncbi.nlm.nih.gov/35904620

المؤلفون: Guangxuan Liu, Yingjie Qi

المصدر: Drug Delivery, Vol 28, Iss 1, Pp 171-182 (2021)
Drug Delivery
article-version (VoR) Version of Record

مصطلحات موضوعية: Carcinoma, Hepatocellular, Berberine, Mice, Nude, Pharmaceutical Science, RM1-950, 02 engineering and technology, Topoisomerase-I Inhibitor, 030226 pharmacology & pharmacy, Microsphere, liver cancer, Mice, 03 medical and health sciences, chemistry.chemical_compound, Drug Delivery Systems, 0302 clinical medicine, Cell Line, Tumor, medicine, Animals, Humans, lipid microsphere, biology, Chemistry, Topoisomerase, Liver Neoplasms, synergistic treatment, General Medicine, Hypoxia-Inducible Factor 1, alpha Subunit, bbr, 021001 nanoscience & nanotechnology, medicine.disease, Antineoplastic Agents, Phytogenic, Xenograft Model Antitumor Assays, Microspheres, Rats, Drug Liberation, 10-hcpt, Cancer research, biology.protein, Camptothecin, Therapeutics. Pharmacology, Topoisomerase I Inhibitors, 0210 nano-technology, Liver cancer, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6578bde835e7c08adeb912a6ca724035
https://doi.org/10.1080/10717544.2020.1870020

المؤلفون: Xiaoxia Yang, Steven Fletcher, Noriko Yanaba, John S. Allen, Julie Ritchey, Julie O'Neal, Grace Cui, Ravi Vij, Mark A. Fiala, Anne H. Schmieder-Atteberry, Kathleen Simons, Francesca Fontana, Michael J. Scott, John F. DiPersio, Dipanjan Pan, Michael P. Rettig, Gregory M. Lanza

المصدر: Clin Cancer Res

مصطلحات موضوعية: 0301 basic medicine, Melphalan, Cancer Research, medicine.medical_treatment, Drug resistance, Integrin alpha4beta1, Dexamethasone, Article, Mice, 03 medical and health sciences, 0302 clinical medicine, In vivo, hemic and lymphatic diseases, Cell Line, Tumor, Cell Adhesion, medicine, Animals, Humans, Multiple myeloma, Chemotherapy, business.industry, Cancer, Prodrug, medicine.disease, Mice, Inbred C57BL, 030104 developmental biology, Oncology, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Cancer research, Nanoparticles, Camptothecin, Topoisomerase I Inhibitors, Multiple Myeloma, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8aff6d0fcdbbb3dfbe4efcc0a6040901
https://doi.org/10.1158/1078-0432.ccr-20-2839

المؤلفون: Bong Seog Kim, Heung Tae Kim, Sang We Kim, Joo Hang Kim, Joung Soon Jang, Dong Wan Kim, Ki Hyeong Lee, Jin-Soo Kim, Ho Jung An, Jin Hyoung Kang, Hye Ryun Kim, Jin-Hyuk Choi

المصدر: British Journal of Cancer

مصطلحات موضوعية: Male, Oncology, Cancer Research, medicine.medical_specialty, Lung Neoplasms, Article, Small-cell lung cancer, law.invention, 03 medical and health sciences, 0302 clinical medicine, Randomized controlled trial, law, Internal medicine, medicine, Clinical endpoint, Humans, Infusions, Intravenous, Lung cancer, Aged, business.industry, Middle Aged, Prognosis, medicine.disease, Small Cell Lung Carcinoma, Clinical trial, Tolerability, 030220 oncology & carcinogenesis, Toxicity, Camptothecin, Female, Topotecan, Neoplasm Recurrence, Local, Topoisomerase I Inhibitors, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cec0695e207b7bfd6edc1c463578ad5
https://doi.org/10.1038/s41416-020-01055-5

المؤلفون: Linda Sciuto, Yves Pommier, Cody J. Peer, William D. Figg, Thomas P. C. Dorlo, Lisa M. Cordes, Anish Thomas, Susan Wroblewski, Alwin D. R. Huitema, Keith T. Schmidt, Ravi A. Madan

المصدر: Cancer Chemotherapy and Pharmacology

مصطلحات موضوعية: Male, Cancer Research, Population, Phases of clinical research, Pharmacology, Toxicology, Models, Biological, Piperazines, Nanoparticle, Pharmacokinetics, NLMEM, Neoplasms, Antineoplastic Combined Chemotherapy Protocols, Nitriles, Phenylthiohydantoin, medicine, Distribution (pharmacology), Humans, Pharmacology (medical), Population pharmacokinetics, education, Aged, Neoplasm Staging, education.field_of_study, Cyclodextrins, Chemistry, Drug release, Middle Aged, Pharmacokinetic analysis, Topoisomerase I, Drug Liberation, Oncology, Benzamides, Phthalazines, Original Article, Camptothecin, Female, Topoisomerase I Inhibitors, medicine.drug, Clearance, Conjugate, Half-Life

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa45f81de46ecd74a5d93ae1ea7af06b
http://europepmc.org/articles/PMC7515962

المؤلفون: Masato Murakami, Taisei Nomura, Tomomichi Ishizaka, Naoyuki Maeda, Ichiro Hayakawa, Kenji Hirotani, Manabu Abe, Tsuyoshi Karibe, Akiko Zembutsu, Yusuke Ogitani, Yuuri Hashimoto, Koji Morita, Takashi Nakada, Yuki Abe, Kenichi Wakita, Yoshinobu Shiose, Takashi Kagari, Kumiko Koyama, Yasuki Kamai, Takuma Iguchi, Toshinori Agatsuma, Suguru Ueno, Yuki Kaneda

المصدر: Clinical Cancer Research. 25:7151-7161

مصطلحات موضوعية: Male, 0301 basic medicine, Cancer Research, Patritumab, Antibody-drug conjugate, Immunoconjugates, Receptor, ErbB-3, media_common.quotation_subject, Mice, Nude, Apoptosis, Antibodies, Monoclonal, Humanized, Mice, 03 medical and health sciences, chemistry.chemical_compound, Drug Delivery Systems, 0302 clinical medicine, Mice, Inbred NOD, Neoplasms, Tumor Cells, Cultured, Animals, Humans, Cytotoxic T cell, Exatecan, skin and connective tissue diseases, Internalization, Cell Proliferation, media_common, Cell growth, Chemistry, Xenograft Model Antitumor Assays, Rats, Gene Expression Regulation, Neoplastic, body regions, Macaca fascicularis, 030104 developmental biology, Oncology, Targeted drug delivery, 030220 oncology & carcinogenesis, Cancer cell, Cancer research, Camptothecin, Topoisomerase I Inhibitors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a3afa8d4ab9bede91d40886d7b382e7
https://doi.org/10.1158/1078-0432.ccr-19-1745

المؤلفون: L. Piazza, C. Contin-Bordes, L. Tran, F. Bonnet, J. Lapoirie, M. E. Truchetet

المساهمون: Hôpital Saint-André, CHU Bordeaux [Bordeaux], Aquitaine Sciences Transfert, Immunology from Concept and Experiments to Translation (ImmunoConcept), Centre National de la Recherche Scientifique (CNRS)-Université de Bordeaux (UB), Hôpital Pellegrin, CHU Bordeaux [Bordeaux]-Groupe hospitalier Pellegrin, Bordeaux population health (BPH), Université de Bordeaux (UB)-Institut de Santé Publique, d'Épidémiologie et de Développement (ISPED)-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre Hospitalier Universitaire de Bordeaux

المصدر: Scientific Reports
Scientific Reports, Nature Publishing Group, 2021, 11 (1), pp.18011. ⟨10.1038/s41598-021-97538-3⟩
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)

مصطلحات موضوعية: MMP1, Metabolite, Pathogenesis, chemistry.chemical_compound, 0302 clinical medicine, Fibrosis, skin and connective tissue diseases, Chemokine CCL2, Skin, Multidisciplinary, integumentary system, Connective tissue disease, 3. Good health, 030220 oncology & carcinogenesis, Medicine, Matrix Metalloproteinase 1, Procollagen, medicine.drug, Cell biology, Science, Immunology, Primary Cell Culture, Irinotecan, Article, Collagen Type I, 03 medical and health sciences, Medical research, Rheumatology, medicine, Humans, RNA, Messenger, Active metabolite, 030203 arthritis & rheumatology, Scleroderma, Systemic, business.industry, Gene Expression Profiling, Fibroblasts, medicine.disease, Actins, Collagen Type I, alpha 1 Chain, Gene Expression Regulation, chemistry, Case-Control Studies, Cancer research, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, Topoisomerase I Inhibitors, business, Camptothecin

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e0f28231ca63847833ccdb814f6d90c
http://hdl.handle.net/20.500.12278/123893

المؤلفون: Xiang Lin Yuan, Kei Muro, Satoshi Morita, Masahito Kotaka, Keun Wook Lee, Joong Bae Ahn, Sang-Hee Cho, Young Suk Park, Dong Sheng Zhang, Tomohiro Nishina, Wei Jia Fang, Ying Yuan, Hiroshi Matsuoka, Masato Nakamura, Satoru Iwasa, Li Bai, Yong Sang Hong, Junichi Sakamoto, Sae-Won Han, Tae Won Kim, Yasuhide Yamada

المصدر: Cancer Science

مصطلحات موضوعية: Adult, Male, Cancer Research, medicine.medical_specialty, Bevacizumab, Genotype, Colorectal cancer, Leucovorin, colorectal cancer, Gastroenterology, Deoxycytidine, Capecitabine, Young Adult, Clinical Research, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Confidence Intervals, Humans, Glucuronosyltransferase, XELIRI, irinotecan, Aged, Aged, 80 and over, business.industry, capecitabine, Hazard ratio, General Medicine, Original Articles, Middle Aged, medicine.disease, Prognosis, Progression-Free Survival, Irinotecan, Treatment Outcome, Oncology, Fluorouracil, FOLFIRI, Camptothecin, Female, Original Article, UGT1A1, Topoisomerase I Inhibitors, business, Colorectal Neoplasms, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ebbcdbdc47220a49ef9cd9b72436967
https://pubmed.ncbi.nlm.nih.gov/34327766