المؤلفون: Ghadge GD; Department of Neurology, University of Chicago School of Medicine, Chicago, IL 60637, USA., Slusher BS, Bodner A, Canto MD, Wozniak K, Thomas AG, Rojas C, Tsukamoto T, Majer P, Miller RJ, Monti AL, Roos RP

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2003 Aug 05; Vol. 100 (16), pp. 9554-9. Date of Electronic Publication: 2003 Jul 22.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0027-8424 (Print) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: Amyotrophic Lateral Sclerosis/*enzymology , Amyotrophic Lateral Sclerosis/*genetics , Carboxypeptidases/*antagonists & inhibitors , Enzyme Inhibitors/*pharmacology , Neurons/*pathology, Adenoviridae/genetics ; Amyotrophic Lateral Sclerosis/metabolism ; Animals ; Cell Death ; Cell Survival ; Glutamate Carboxypeptidase II ; Glutamic Acid/metabolism ; Mice ; Mice, Transgenic ; Motor Neurons/metabolism ; Neurons/enzymology ; Time Factors

المؤلفون: Rojas C; Guilford Pharmaceuticals Inc., 6611 Tributary Street, Baltimore, Maryland 21224 USA., Thomas AG, Majer P, Tsukamoto T, Lu XM, Vornov JJ, Wozniak KM, Slusher BS

المصدر: Advances in experimental medicine and biology [Adv Exp Med Biol] 2003; Vol. 524, pp. 205-13.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 0121103 Publication Model: Print Cited Medium: Print ISSN: 0065-2598 (Print) Linking ISSN: 00652598 NLM ISO Abbreviation: Adv Exp Med Biol Subsets: MEDLINE

مواضيع طبية MeSH: Carboxypeptidases/*metabolism , Protease Inhibitors/*pharmacology , Protease Inhibitors/*therapeutic use, Animals ; Brain/enzymology ; Brain Injuries/prevention & control ; Disease Models, Animal ; Glutamate Carboxypeptidase II ; Ischemic Attack, Transient/drug therapy ; Kidney/enzymology ; Neuroprotective Agents/pharmacology ; Neuroprotective Agents/therapeutic use ; Organophosphorus Compounds/pharmacology ; Organophosphorus Compounds/therapeutic use

المؤلفون: Thomas AG; Guilford Pharmaceuticals Inc., 6611 Tributary Street, Baltimore, MD 21224, USA., Liu W, Olkowski JL, Tang Z, Lin Q, Lu XC, Slusher BS

المصدر: European journal of pharmacology [Eur J Pharmacol] 2001 Oct 26; Vol. 430 (1), pp. 33-40.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print Cited Medium: Print ISSN: 0014-2999 (Print) Linking ISSN: 00142999 NLM ISO Abbreviation: Eur J Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Brain/*drug effects , Carboxypeptidases/*antagonists & inhibitors , Transforming Growth Factor beta/*pharmacology, Animals ; Antibodies/pharmacology ; Arterial Occlusive Diseases/prevention & control ; Brain/blood supply ; Brain/enzymology ; Cells, Cultured ; Cerebral Arteries/drug effects ; Disease Models, Animal ; Enzyme Inhibitors/pharmacology ; Glutamate Carboxypeptidase II ; Neuroprotective Agents/pharmacology ; Precipitin Tests ; Rats ; Rats, Sprague-Dawley ; Receptors, Metabotropic Glutamate/drug effects ; Transforming Growth Factor beta/analysis ; Transforming Growth Factor beta/immunology

المؤلفون: Thomas AG; Guilford Pharmaceuticals Inc., 6611 Tributary Street, Baltimore, MD 21224, USA., Olkowski JL, Slusher BS

المصدر: European journal of pharmacology [Eur J Pharmacol] 2001 Aug 24; Vol. 426 (1-2), pp. 35-8.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print Cited Medium: Print ISSN: 0014-2999 (Print) Linking ISSN: 00142999 NLM ISO Abbreviation: Eur J Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Carboxypeptidases/*antagonists & inhibitors , Dipeptides/*pharmacology , Neuroglia/*drug effects , Neuroprotective Agents/*pharmacology , Receptors, Metabotropic Glutamate/*drug effects, Animals ; Benzoates/pharmacology ; Carboxypeptidases/metabolism ; Cells, Cultured ; Excitatory Amino Acid Antagonists/pharmacology ; Female ; Glutamate Carboxypeptidase II ; Glycine/analogs & derivatives ; Glycine/pharmacology ; Neuroglia/cytology ; Neuroglia/metabolism ; Organophosphorus Compounds/pharmacology ; Rats ; Receptors, Metabotropic Glutamate/metabolism

المؤلفون: Thomas AG; Guilford Pharmaceuticals Inc., Baltimore, Maryland, USA., Vornov JJ, Olkowski JL, Merion AT, Slusher BS

المصدر: The Journal of pharmacology and experimental therapeutics [J Pharmacol Exp Ther] 2000 Oct; Vol. 295 (1), pp. 16-22.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Society for Pharmacology and Experimental Therapeutics Country of Publication: United States NLM ID: 0376362 Publication Model: Print Cited Medium: Print ISSN: 0022-3565 (Print) Linking ISSN: 00223565 NLM ISO Abbreviation: J Pharmacol Exp Ther Subsets: MEDLINE

مواضيع طبية MeSH: Brain/*drug effects , Carboxypeptidases/*physiology , Dipeptides/*pharmacology , Neuroprotective Agents/*pharmacology, Animals ; Carboxypeptidases/antagonists & inhibitors ; Cells, Cultured ; Dipeptides/metabolism ; Dipeptides/toxicity ; Female ; Glutamate Carboxypeptidase II ; N-Methylaspartate/toxicity ; Pregnancy ; Rats ; Rats, Sprague-Dawley ; Receptors, N-Methyl-D-Aspartate/drug effects

المؤلفون: Slusher BS; Guilford Pharmaceuticals, Department of Research, Baltimore, Maryland 21224, USA. slusher_b@guilfordpharm.com, Vornov JJ, Thomas AG, Hurn PD, Harukuni I, Bhardwaj A, Traystman RJ, Robinson MB, Britton P, Lu XC, Tortella FC, Wozniak KM, Yudkoff M, Potter BM, Jackson PF

المصدر: Nature medicine [Nat Med] 1999 Dec; Vol. 5 (12), pp. 1396-402.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print Cited Medium: Print ISSN: 1078-8956 (Print) Linking ISSN: 10788956 NLM ISO Abbreviation: Nat Med Subsets: MEDLINE

مواضيع طبية MeSH: Brain Ischemia/*prevention & control , Carboxypeptidases/*antagonists & inhibitors , Enzyme Inhibitors/*pharmacology , Neuroprotective Agents/*pharmacology , Organophosphorus Compounds/*pharmacology, Animals ; Brain Ischemia/metabolism ; Carboxypeptidases/metabolism ; Culture Techniques ; Dipeptides/metabolism ; Disease Models, Animal ; Drug Tolerance ; Glutamate Carboxypeptidase II ; Glutamic Acid/metabolism ; Ischemic Attack, Transient/drug therapy ; Ischemic Attack, Transient/metabolism ; Mice ; Mice, Inbred ICR ; Rats ; Rats, Sprague-Dawley ; Stroke/drug therapy ; Stroke/metabolism

المؤلفون: Thomas AG; Guilford Pharmaceuticals, 6611 Tributary Street, Baltimore, MD 21224, USA., Olkowski JL, Vornov JJ, Slusher BS

المصدر: Brain research [Brain Res] 1999 Oct 02; Vol. 843 (1-2), pp. 48-52.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 0045503 Publication Model: Print Cited Medium: Print ISSN: 0006-8993 (Print) Linking ISSN: 00068993 NLM ISO Abbreviation: Brain Res Subsets: MEDLINE

مواضيع طبية MeSH: Carboxypeptidases/*antagonists & inhibitors , Enzyme Inhibitors/*pharmacology , Methotrexate/*analogs & derivatives , Neurons/*drug effects , Neurotoxins/*toxicity , Organophosphorus Compounds/*pharmacology, 6-Cyano-7-nitroquinoxaline-2,3-dione/pharmacology ; Animals ; Benzoates/pharmacology ; Cells, Cultured ; Cerebral Cortex/cytology ; Cerebral Cortex/physiology ; Deoxyglucose/pharmacology ; Dizocilpine Maleate/pharmacology ; Dose-Response Relationship, Drug ; Excitatory Amino Acid Antagonists/pharmacology ; Fetus ; Glutamate Carboxypeptidase II ; Glycine/analogs & derivatives ; Glycine/pharmacology ; Methotrexate/antagonists & inhibitors ; Methotrexate/toxicity ; N-Methylaspartate/pharmacology ; Neurons/cytology ; Neurons/physiology ; Potassium Cyanide/pharmacology ; Pyrrolidines/pharmacology ; Rats