المؤلفون: Brennen WN; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center (SKCCC), Johns Hopkins University, Baltimore, Maryland, USA.; Department of Urology, James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Zhu Y; Department of Urology, James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Coleman IM; Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., Dalrymple SL; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center (SKCCC), Johns Hopkins University, Baltimore, Maryland, USA., Antony L; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center (SKCCC), Johns Hopkins University, Baltimore, Maryland, USA., Patel RA; Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., Hanratty B; Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., Chikarmane R; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center (SKCCC), Johns Hopkins University, Baltimore, Maryland, USA., Meeker AK; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center (SKCCC), Johns Hopkins University, Baltimore, Maryland, USA.; Department of Urology, James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; Department of Pathology, SKCCC, Johns Hopkins University, Baltimore, Maryland, USA., Zheng SL; Program for Personalized Cancer Care, North Shore University Health System, Evanston, Illinois, USA., Hooper JE; Department of Pathology, SKCCC, Johns Hopkins University, Baltimore, Maryland, USA., Luo J; Department of Urology, James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., De Marzo AM; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center (SKCCC), Johns Hopkins University, Baltimore, Maryland, USA.; Department of Urology, James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; Department of Pathology, SKCCC, Johns Hopkins University, Baltimore, Maryland, USA., Corey E; Department of Urology and., Xu J; Program for Personalized Cancer Care, North Shore University Health System, Evanston, Illinois, USA., Yegnasubramanian S; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center (SKCCC), Johns Hopkins University, Baltimore, Maryland, USA.; Department of Pathology, SKCCC, Johns Hopkins University, Baltimore, Maryland, USA., Haffner MC; Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.; Department of Pathology, University of Washington, Seattle, Washington, USA., Nelson PS; Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.; Department of Urology and., Nelson WG; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center (SKCCC), Johns Hopkins University, Baltimore, Maryland, USA.; Department of Urology, James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; Department of Pathology, SKCCC, Johns Hopkins University, Baltimore, Maryland, USA., Isaacs WB; Department of Urology, James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Isaacs JT; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center (SKCCC), Johns Hopkins University, Baltimore, Maryland, USA.; Department of Urology, James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; Department of Pathology, SKCCC, Johns Hopkins University, Baltimore, Maryland, USA.

المصدر: JCI insight [JCI Insight] 2021 Apr 22; Vol. 6 (8). Date of Electronic Publication: 2021 Apr 22.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: Electronic Cited Medium: Internet ISSN: 2379-3708 (Electronic) Linking ISSN: 23793708 NLM ISO Abbreviation: JCI Insight Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Neuroendocrine/*genetics , Cell Transformation, Neoplastic/*genetics , Drug Resistance, Neoplasm/*genetics , Prostatic Neoplasms, Castration-Resistant/*genetics, Abiraterone Acetate/therapeutic use ; Animals ; Antineoplastic Agents/therapeutic use ; Benzamides/therapeutic use ; Carcinoma, Neuroendocrine/metabolism ; Enhancer of Zeste Homolog 2 Protein/genetics ; Male ; Mice ; Neoplasm Transplantation ; Nitriles/therapeutic use ; PTEN Phosphohydrolase/genetics ; Phenylthiohydantoin/therapeutic use ; Prostatic Neoplasms, Castration-Resistant/drug therapy ; Prostatic Neoplasms, Castration-Resistant/metabolism ; Receptors, Androgen/genetics ; Retinoblastoma Binding Proteins/genetics ; SOXB1 Transcription Factors/genetics ; Thiohydantoins/therapeutic use ; Tumor Suppressor Protein p53/genetics ; Ubiquitin-Protein Ligases/genetics

المؤلفون: de Wilde RF; Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Heaphy CM, Maitra A, Meeker AK, Edil BH, Wolfgang CL, Ellison TA, Schulick RD, Molenaar IQ, Valk GD, Vriens MR, Borel Rinkes IH, Offerhaus GJ, Hruban RH, Matsukuma KE

المصدر: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc [Mod Pathol] 2012 Jul; Vol. 25 (7), pp. 1033-9. Date of Electronic Publication: 2012 May 11.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Inc Country of Publication: United States NLM ID: 8806605 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1530-0285 (Electronic) Linking ISSN: 08933952 NLM ISO Abbreviation: Mod Pathol Subsets: MEDLINE

مواضيع طبية MeSH: Adaptor Proteins, Signal Transducing/*biosynthesis , Carcinoma, Neuroendocrine/*metabolism , DNA Helicases/*biosynthesis , Nuclear Proteins/*biosynthesis , Pancreatic Neoplasms/*metabolism , Telomere/*pathology, Adenoma/etiology ; Adenoma/metabolism ; Adenoma/pathology ; Adult ; Aged ; Aged, 80 and over ; Carcinoma, Neuroendocrine/etiology ; Carcinoma, Neuroendocrine/pathology ; Co-Repressor Proteins ; Female ; Humans ; Immunohistochemistry ; In Situ Hybridization, Fluorescence ; Male ; Middle Aged ; Molecular Chaperones ; Multiple Endocrine Neoplasia Type 1/complications ; Pancreatic Neoplasms/etiology ; Pancreatic Neoplasms/pathology ; Phenotype ; Telomere/metabolism ; X-linked Nuclear Protein ; Young Adult

المؤلفون: Heaphy CM; Department of Pathology, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins Medical Institutions, Baltimore, MD 21231, USA., de Wilde RF, Jiao Y, Klein AP, Edil BH, Shi C, Bettegowda C, Rodriguez FJ, Eberhart CG, Hebbar S, Offerhaus GJ, McLendon R, Rasheed BA, He Y, Yan H, Bigner DD, Oba-Shinjo SM, Marie SK, Riggins GJ, Kinzler KW, Vogelstein B, Hruban RH, Maitra A, Papadopoulos N, Meeker AK

المصدر: Science (New York, N.Y.) [Science] 2011 Jul 22; Vol. 333 (6041), pp. 425. Date of Electronic Publication: 2011 Jun 30.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

مواضيع طبية MeSH: Adaptor Proteins, Signal Transducing/*genetics , Carcinoma, Neuroendocrine/*genetics , Central Nervous System Neoplasms/*genetics , DNA Helicases/*genetics , Nuclear Proteins/*genetics , Pancreatic Neoplasms/*genetics , Telomere/*physiology, Adaptor Proteins, Signal Transducing/metabolism ; Carcinoma, Neuroendocrine/pathology ; Carcinoma, Neuroendocrine/physiopathology ; Cell Nucleus/metabolism ; Central Nervous System Neoplasms/pathology ; Central Nervous System Neoplasms/physiopathology ; Chromatin Assembly and Disassembly ; Co-Repressor Proteins ; DNA Helicases/metabolism ; Humans ; In Situ Hybridization, Fluorescence ; Molecular Chaperones ; Mutant Proteins/genetics ; Mutant Proteins/metabolism ; Mutation ; Nuclear Proteins/metabolism ; Pancreatic Neoplasms/pathology ; Pancreatic Neoplasms/physiopathology ; Phenotype ; Telomere/ultrastructure ; X-linked Nuclear Protein