المؤلفون: Ruscetti M; Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Morris JP 4th; Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Mezzadra R; Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Russell J; Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Leibold J; Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Romesser PB; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Simon J; Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Kulick A; Department of Molecular Pharmacology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Ho YJ; Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Fennell M; Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Li J; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Norgard RJ; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Wilkinson JE; Department of Pathology, University of Michigan School of Medicine, Ann Arbor, MI 48109, USA., Alonso-Curbelo D; Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Sridharan R; Department of Molecular Pharmacology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Weill Cornell Medical College, Cornell University, New York, NY 10065, USA., Heller DA; Department of Molecular Pharmacology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Weill Cornell Medical College, Cornell University, New York, NY 10065, USA., de Stanchina E; Department of Molecular Pharmacology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Stanger BZ; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Sherr CJ; Department of Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA., Lowe SW; Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA. Electronic address: lowes@mskcc.org.

المصدر: Cell [Cell] 2020 Apr 16; Vol. 181 (2), pp. 424-441.e21. Date of Electronic Publication: 2020 Mar 31.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE

مواضيع طبية MeSH: Aging/*physiology , Carcinoma, Pancreatic Ductal/*pathology , Vascular Remodeling/*physiology, Animals ; CD8-Positive T-Lymphocytes/immunology ; Carcinoma, Pancreatic Ductal/microbiology ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cyclin-Dependent Kinase 4/metabolism ; Cyclin-Dependent Kinase 6/metabolism ; Gene Expression Regulation, Neoplastic/genetics ; Genes, ras/genetics ; Humans ; Immunotherapy/methods ; MAP Kinase Signaling System/physiology ; Mice ; Pancreatic Neoplasms/pathology ; Retinoblastoma Protein/immunology ; Signal Transduction/genetics ; Tumor Microenvironment ; Vascular Remodeling/genetics