المؤلفون: How C; Ontario Cancer Institute, Princess Margaret Hospital, University Health Network, Toronto, Ontario, Canada., Hui AB, Alajez NM, Shi W, Boutros PC, Clarke BA, Yan R, Pintilie M, Fyles A, Hedley DW, Hill RP, Milosevic M, Liu FF

المصدر: PloS one [PLoS One] 2013 Jul 04; Vol. 8 (7), pp. e67846. Date of Electronic Publication: 2013 Jul 04 (Print Publication: 2013).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

مواضيع طبية MeSH: Gene Expression Regulation, Neoplastic*, Carcinoma, Squamous Cell/*genetics , Homeodomain Proteins/*genetics , MicroRNAs/*genetics , RNA, Messenger/*genetics , Uterine Cervical Neoplasms/*genetics , Vascular Endothelial Growth Factor A/*genetics, Adult ; Aged ; Aged, 80 and over ; Antineoplastic Agents/therapeutic use ; Carcinoma, Squamous Cell/metabolism ; Carcinoma, Squamous Cell/mortality ; Carcinoma, Squamous Cell/therapy ; Cell Line, Tumor ; Cell Proliferation ; Female ; Gamma Rays/therapeutic use ; Homeodomain Proteins/antagonists & inhibitors ; Homeodomain Proteins/metabolism ; Humans ; MicroRNAs/metabolism ; Middle Aged ; RNA, Messenger/metabolism ; RNA, Small Interfering/genetics ; RNA, Small Interfering/metabolism ; Signal Transduction ; Survival Analysis ; Transcription, Genetic ; Uterine Cervical Neoplasms/metabolism ; Uterine Cervical Neoplasms/mortality ; Uterine Cervical Neoplasms/therapy ; Vascular Endothelial Growth Factor A/antagonists & inhibitors ; Vascular Endothelial Growth Factor A/metabolism

المؤلفون: Chaudary N; Ontario Cancer Institute/Princess Margaret Hospital, Campbell Family Institute for Cancer Research and University of Toronto, Toronto, Ontario, Canada., Hedley DW, Hill RP

المصدر: Current protocols in pharmacology [Curr Protoc Pharmacol] 2011 Jun; Vol. Chapter 14, pp. Unit 14.19.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Country of Publication: United States NLM ID: 9717249 Publication Model: Print Cited Medium: Internet ISSN: 1934-8290 (Electronic) Linking ISSN: 19348282 NLM ISO Abbreviation: Curr Protoc Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents/*therapeutic use , Carcinoma, Squamous Cell/*drug therapy , Drug Discovery/*methods , Lymphatic Metastasis/*prevention & control , Tumor Microenvironment/*physiology , Uterine Cervical Neoplasms/*drug therapy , Uterine Cervical Neoplasms/*pathology , Xenograft Model Antitumor Assays/*methods, Animals ; Carcinoma, Squamous Cell/pathology ; Female ; Humans ; Lymphatic Metastasis/physiopathology

المؤلفون: Schwock J; Ontario Cancer Institute, Departments of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada., Dhani N, Cao MP, Zheng J, Clarkson R, Radulovich N, Navab R, Horn LC, Hedley DW

المصدر: Cancer research [Cancer Res] 2009 Jun 01; Vol. 69 (11), pp. 4750-9. Date of Electronic Publication: 2009 May 19.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Benzoquinones/*therapeutic use , Carcinoma, Squamous Cell/*drug therapy , Cell Proliferation/*drug effects , Focal Adhesion Protein-Tyrosine Kinases/*antagonists & inhibitors , HSP90 Heat-Shock Proteins/*antagonists & inhibitors , Lactams, Macrocyclic/*therapeutic use , Protein-Tyrosine Kinases/*therapeutic use , Uterine Cervical Neoplasms/*drug therapy, Animals ; Antineoplastic Agents/therapeutic use ; Benzoquinones/administration & dosage ; Carcinoma, Squamous Cell/genetics ; Carcinoma, Squamous Cell/pathology ; Cell Line, Tumor ; Disease Progression ; Drug Delivery Systems/methods ; Female ; Focal Adhesion Protein-Tyrosine Kinases/genetics ; Gene Targeting ; Genes, Dominant/physiology ; Humans ; Lactams, Macrocyclic/administration & dosage ; Mice ; Mice, SCID ; Neoplasm Metastasis ; Protein-Tyrosine Kinases/administration & dosage ; Protein-Tyrosine Kinases/genetics ; Tumor Burden/drug effects ; Uterine Cervical Neoplasms/genetics ; Uterine Cervical Neoplasms/pathology ; Xenograft Model Antitumor Assays

المؤلفون: Agulnik M; Princess Margaret Hospital Phase II Consortium, Toronto, Ontario, Canada., da Cunha Santos G, Hedley D, Nicklee T, Dos Reis PP, Ho J, Pond GR, Chen H, Chen S, Shyr Y, Winquist E, Soulieres D, Chen EX, Squire JA, Marrano P, Kamel-Reid S, Dancey J, Siu LL, Tsao MS

المصدر: Journal of clinical oncology : official journal of the American Society of Clinical Oncology [J Clin Oncol] 2007 Jun 01; Vol. 25 (16), pp. 2184-90.

نوع المنشور: Clinical Trial, Phase I; Clinical Trial, Phase II; Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Society of Clinical Oncology Country of Publication: United States NLM ID: 8309333 Publication Model: Print Cited Medium: Internet ISSN: 1527-7755 (Electronic) Linking ISSN: 0732183X NLM ISO Abbreviation: J Clin Oncol Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Squamous Cell/*drug therapy , ErbB Receptors/*antagonists & inhibitors , Head and Neck Neoplasms/*drug therapy , Protein Kinase Inhibitors/*therapeutic use , Quinazolines/*therapeutic use , Skin/*chemistry, Biomarkers, Tumor ; Biopsy ; Carcinoma, Squamous Cell/pathology ; Carcinoma, Squamous Cell/secondary ; ErbB Receptors/analysis ; ErbB Receptors/genetics ; Erlotinib Hydrochloride ; Gene Dosage ; Head and Neck Neoplasms/pathology ; Humans ; Neoplasm Recurrence, Local ; Skin/pathology

المؤلفون: Birle DC; Division of Applied Molecular Oncology, Ontario Cancer Institute, Princess Margaret Hospital and University of Toronto, 610 University Avenue, Toronto, Ontario, Canada., Hedley DW

المصدر: Cancer research [Cancer Res] 2007 Feb 15; Vol. 67 (4), pp. 1735-43.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print Cited Medium: Print ISSN: 0008-5472 (Print) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Boronic Acids/*pharmacology , Carcinoma, Squamous Cell/*drug therapy , Hypoxia-Inducible Factor 1, alpha Subunit/*antagonists & inhibitors , Leupeptins/*pharmacology , Protease Inhibitors/*pharmacology , Pyrazines/*pharmacology , Uterine Cervical Neoplasms/*drug therapy, Antigens, Neoplasm/biosynthesis ; Antineoplastic Agents/pharmacology ; Bortezomib ; Carbonic Anhydrase IX ; Carbonic Anhydrases/biosynthesis ; Carcinoma, Squamous Cell/enzymology ; Carcinoma, Squamous Cell/metabolism ; Caspase 3/metabolism ; Cell Hypoxia/physiology ; Cell Line, Tumor ; Cell Nucleus/metabolism ; Colonic Neoplasms/drug therapy ; Colonic Neoplasms/metabolism ; E1A-Associated p300 Protein/metabolism ; Enzyme Activation/drug effects ; Female ; Humans ; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism ; Male ; Prostatic Neoplasms/drug therapy ; Prostatic Neoplasms/metabolism ; Protein Binding ; Uterine Cervical Neoplasms/enzymology ; Uterine Cervical Neoplasms/metabolism ; Vascular Endothelial Growth Factor A/biosynthesis ; Xenograft Model Antitumor Assays

المؤلفون: Yip KW; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada., Ito E, Mao X, Au PY, Hedley DW, Mocanu JD, Bastianutto C, Schimmer A, Liu FF

المصدر: Molecular cancer therapeutics [Mol Cancer Ther] 2006 Sep; Vol. 5 (9), pp. 2234-40.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for Cancer Research, Inc Country of Publication: United States NLM ID: 101132535 Publication Model: Print Cited Medium: Print ISSN: 1535-7163 (Print) Linking ISSN: 15357163 NLM ISO Abbreviation: Mol Cancer Ther Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents/*pharmacology , Apoptosis/*drug effects , Biguanides/*pharmacology , Carcinoma, Squamous Cell/*drug therapy , Hypopharyngeal Neoplasms/*drug therapy, Animals ; Antineoplastic Combined Chemotherapy Protocols/pharmacology ; Biguanides/administration & dosage ; Carcinoma, Squamous Cell/pathology ; Caspase 2/metabolism ; Caspase 9/metabolism ; Cisplatin/administration & dosage ; Enzyme Activation/drug effects ; Female ; Fluorouracil/administration & dosage ; Humans ; Hypopharyngeal Neoplasms/pathology ; Membrane Potentials/drug effects ; Mice ; Mice, Inbred BALB C ; Mice, SCID ; Mitochondrial Membranes/drug effects ; Mitochondrial Membranes/physiology ; NIH 3T3 Cells ; Xenograft Model Antitumor Assays