المؤلفون: Gill RG; Departments of Surgery and Immunology, University of Colorado Denver, Aurora, CO ronald.gill@ucdenver.edu., Pagni PP; La Jolla Institute for Allergy and Immunology, La Jolla, CA., Kupfer T; Departments of Surgery and Immunology, University of Colorado Denver, Aurora, CO., Wasserfall CH; Department of Pathology, University of Florida, Gainesville, FL., Deng S; Yale University School of Medicine, New Haven, CT., Posgai A; Department of Pathology, University of Florida, Gainesville, FL., Manenkova Y; La Jolla Institute for Allergy and Immunology, La Jolla, CA., Bel Hani A; La Jolla Institute for Allergy and Immunology, La Jolla, CA., Straub L; Immune Tolerance Network, University of California, San Francisco, San Francisco, CA., Bernstein P; Immune Tolerance Network, Bethesda, MD., Atkinson MA; Department of Pathology, University of Florida, Gainesville, FL., Herold KC; Yale University School of Medicine, New Haven, CT., von Herrath M; La Jolla Institute for Allergy and Immunology, La Jolla, CA., Staeva T; JDRF, New York, NY., Ehlers MR; Immune Tolerance Network, University of California, San Francisco, San Francisco, CA., Nepom GT; Benaroya Research Institute, Seattle, WA.

المصدر: Diabetes [Diabetes] 2016 May; Vol. 65 (5), pp. 1310-6. Date of Electronic Publication: 2015 Dec 30.

نوع المنشور: Comparative Study; Journal Article

بيانات الدورية: Publisher: American Diabetes Association Country of Publication: United States NLM ID: 0372763 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1939-327X (Electronic) Linking ISSN: 00121797 NLM ISO Abbreviation: Diabetes Subsets: MEDLINE

مواضيع طبية MeSH: Antibodies, Monoclonal/*administration & dosage , Autoimmune Diseases/*drug therapy , CD3 Complex/*chemistry , Diabetes Mellitus, Type 1/*drug therapy , Insulin/*metabolism , Insulin-Secreting Cells/*drug effects , Interleukin-1beta/*antagonists & inhibitors, Animals ; Antibodies, Monoclonal/chemistry ; Antibodies, Monoclonal/therapeutic use ; Autoimmune Diseases/immunology ; Autoimmune Diseases/metabolism ; Biomedical Research/methods ; CD3 Complex/metabolism ; Diabetes Mellitus, Type 1/immunology ; Diabetes Mellitus, Type 1/metabolism ; Drug Administration Schedule ; Drug Therapy, Combination ; Female ; Immunoglobulin Fab Fragments/administration & dosage ; Immunoglobulin Fab Fragments/chemistry ; Immunoglobulin Fab Fragments/therapeutic use ; Immunotherapy/methods ; Insulin Secretion ; Insulin-Secreting Cells/immunology ; Insulin-Secreting Cells/metabolism ; Interleukin-1 Receptor Accessory Protein/antagonists & inhibitors ; Interleukin-1 Receptor Accessory Protein/metabolism ; Interleukin-1beta/metabolism ; Mice, Inbred NOD ; Multicenter Studies as Topic ; Pilot Projects ; Receptors, Interleukin-1 Type I/antagonists & inhibitors ; Receptors, Interleukin-1 Type I/metabolism ; Recombinant Fusion Proteins/therapeutic use ; Reproducibility of Results ; Research Design ; Specific Pathogen-Free Organisms ; United States