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المؤلفون: Ian Parker, Jeffrey T. Lock
مصطلحات موضوعية: Biochemistry & Molecular Biology, Physiology, Medical Physiology, Calcium imaging, IP3 receptor, Gating, IP3 signaling, chemistry.chemical_compound, stomatognathic system, Molecular Biology, 5-Trisphosphate Receptors, IP(3) signaling, Calcium signaling, 5-Trisphosphate, Ca(2+) puffs, Inositol trisphosphate, Cell Biology, Inositol trisphosphate receptor, Ca2+ puffs, Inositol 1, respiratory tract diseases, body regions, Kinetics, chemistry, Biophysics, Liberation, Calcium, sense organs, IP(3) receptor, Biochemistry and Cell Biology
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81fd5647c2404d265b426b09b72b1e0d
https://escholarship.org/uc/item/1079w5bq -
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المؤلفون: Paula Farias, Armen Zakarian, Jordi Molgó, Artur K. Mailyan, Maša Podunavac, Jeffrey J. Jackson, Cesar Cardenas, Hernan Huerta, Alenka Lovy
المساهمون: CEA- Saclay (CEA), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)
المصدر: Angewandte Chemie (International ed. in English), vol 60, iss 20
Angewandte Chemie International Edition
Angewandte Chemie International Edition, 2021, 60 (20), pp.11278-11282. ⟨10.1002/anie.202102259⟩
Angew Chem Int Ed Englمصطلحات موضوعية: Cell type, Cell Survival, [SDV]Life Sciences [q-bio], Antineoplastic Agents, 010402 general chemistry, Drug Screening Assays, 01 natural sciences, Catalysis, Article, Cell Line, chemistry.chemical_compound, Cell Line, Tumor, medicine, Inositol 1,4,5-Trisphosphate Receptors, [CHIM]Chemical Sciences, Humans, cancer, IP3R receptor, total synthesis, ComputingMilieux_MISCELLANEOUS, 5-Trisphosphate Receptors, Calcium signaling, Cell Proliferation, Biological Products, Natural product, Tumor, xestospongins, Molecular Structure, 010405 organic chemistry, Organic Chemistry, Cancer, Total synthesis, General Chemistry, Antitumor, General Medicine, medicine.disease, Inositol 1, 0104 chemical sciences, Cell biology, Mitochondria, chemistry, Cancer cell, Chemical Sciences, Lactam, Drug Screening Assays, Antitumor, metabolism, Function (biology)
وصف الملف: application/pdf
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المؤلفون: Bo Sun, Mingke Ni, Shanshan Tian, Wenting Guo, Shitian Cai, Mads T. Sondergaard, Yongxiang Chen, Yongxin Mu, John P. Estillore, Ruiwu Wang, Ju Chen, Michael T. Overgaard, Michael Fill, Josefina Ramos‐Franco, Mette Nyegaard, Sui Rong Wayne Chen
المصدر: Sun, B, Ni, M, Tian, S, Guo, W, Cai, S, Sondergaard, M T, Chen, Y, Mu, Y, Estillore, J P, Wang, R, Chen, J, Overgaard, M T, Fill, M, Ramos-Franco, J, Nyegaard, M & Wayne Chen, S R 2022, ' A gain-of-function mutation in the ITPR1 gating domain causes male infertility in mice ', Journal of Cellular Physiology, vol. 237, no. 8, pp. 3305-3316 . https://doi.org/10.1002/jcp.30783
Sun, B, Ni, M, Tian, S, Guo, W, Cai, S, Sondergaard, M T, Chen, Y, Mu, Y, Estillore, J P, Wang, R, Chen, J, Overgaard, M T, Fill, M, Ramos-Franco, J, Nyegaard, M & Wayne Chen, S R 2022, ' A gain-of-function mutation in the ITPR1 gating domain causes male infertility in mice ', Journal of cellular physiology, vol. 237, no. 8, pp. 3305-3316 . https://doi.org/10.1002/jcp.30783مصطلحات موضوعية: EXPRESSION, Male, Gain of Function Mutation/genetics, Calcium/metabolism, Mutation/genetics, Physiology, Clinical Biochemistry, Inositol 1,4,5-Trisphosphate, gain-of-function mutation, CA2+ RELEASE, male infertility, Infertility, Male/genetics, Mice, Inositol 1,4,5-Trisphosphate Receptors/genetics, Animals, Humans, Inositol 1,4,5-Trisphosphate Receptors, intracellular Ca2+ release, INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR, TYPE-1, Infertility, Male, SPINOCEREBELLAR ATAXIA, CHANNELS, intracellular Ca release, azoospermia, NEURODEGENERATION, Cell Biology, HEK293 Cells, Gain of Function Mutation, Mutation, 5-trisphosphate receptor, Calcium, acrosome, inositol 1, Inositol, SPERM
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المؤلفون: Ryan H. Moy, Alexander Nguyen, Jia Min Loo, Norihiro Yamaguchi, Christina M. Kajba, Balaji Santhanam, Benjamin N. Ostendorf, Y. Gloria Wu, Saeed Tavazoie, Sohail F. Tavazoie
المصدر: Dev Cell
Developmental cell, vol 57, iss 9مصطلحات موضوعية: colorectal cancer, RELB, Medical and Health Sciences, Article, General Biochemistry, Genetics and Molecular Biology, Genetics, metastasis, Humans, Inositol 1,4,5-Trisphosphate Receptors, Molecular Biology, 5-Trisphosphate Receptors, Cancer, calcium, hypoxia, Liver Disease, Prevention, Liver Neoplasms, Transcription Factor RelB, ITPR3, NF-kappa B, Cell Biology, Biological Sciences, Inositol 1, non-canonical NF-κB, Colo-Rectal Cancer, Calcium, Digestive Diseases, Colorectal Neoplasms, Developmental Biology
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1617410d797f3e3e052cc19d5019076b
https://doi.org/10.1016/j.devcel.2022.04.010 -
5Spatial-temporal patterning of Ca2+ signals by the subcellular distribution of IP3 and IP3 receptors
المؤلفون: Ian Parker, Jeffrey T. Lock, Ian F. Smith
المصدر: Semin Cell Dev Biol
مصطلحات موضوعية: 0301 basic medicine, Inositol 1,4,5-Trisphosphate, Gating, Biology, Ca(2+) signaling, Article, Image analysis, Paediatrics and Reproductive Medicine, 03 medical and health sciences, 0302 clinical medicine, Inositol 1,4,5-Trisphosphate Receptors, Animals, Humans, Calcium Signaling, Receptor, Ca2+ signaling, 5-Trisphosphate Receptors, 5-Trisphosphate, Ca(2+) puffs, Endoplasmic reticulum, Cell Biology, IP(3) receptors, IP3 receptors, Inositol trisphosphate receptor, Ca2+ puffs, Inositol 1, Cell biology, Subcellular distribution, 030104 developmental biology, Calcium, Generic health relevance, Biochemistry and Cell Biology, 030217 neurology & neurosurgery, Entire cell, Developmental Biology
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc052f5d9778f3b3c7b1613c719fe935
https://escholarship.org/uc/item/9365x264 -
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المؤلفون: Keith E. Mostov, Álvaro Román-Fernández, Mohammed A. Mansour, Lynn McGarry, David M. Bryant, Julie Roignot, Emma Shanks, Marisa Nacke, Emma Sandilands
المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Nature communications, vol 9, iss 1
Nature Communications
Roman-Fernandez, Alvaro; Roignot, Julie; Sandilands, Emma; Nacke, Marisa; Mansour, Mohammed A; McGarry, Lynn; et al.(2018). The phospholipid PI(3,4)P-2 is an apical identity determinant. NATURE COMMUNICATIONS, 9(1), 5041. doi: 10.1038/s41467-018-07464-8. UCSF: Retrieved from: http://www.escholarship.org/uc/item/8vf614x7مصطلحات موضوعية: 0301 basic medicine, Endosome, 1.1 Normal biological development and functioning, Science, Endocytic cycle, General Physics and Astronomy, Endosomes, Phosphatidylinositols, Article, General Biochemistry, Genetics and Molecular Biology, Madin Darby Canine Kidney Cells, Extracellular matrix, 03 medical and health sciences, chemistry.chemical_compound, Dogs, Underpinning research, MD Multidisciplinary, Cell polarity, Pi, Animals, Phosphatidylinositol, lcsh:Science, Multidisciplinary, Vesicle, 5-Trisphosphate 5-Phosphatases, Phosphatidylinositol-3, General Chemistry, Intracellular Membranes, Apical membrane, Cell biology, 030104 developmental biology, chemistry, Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases, lcsh:Q
وصف الملف: application/pdf; text
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المؤلفون: Siting Zhu, Kunfu Ouyang, Xi Fang, Beili Zhao, Huayuan Tang, Ju Chen, Ran Jing, Christa Trexler, Yali Li, Jie Liu, Hong Wang, Zhixiang Pan
المصدر: Journal of gastroenterology, vol 54, iss 5
مصطلحات موضوعية: Oral and gastrointestinal, Potassium Chloride, Mice, chemistry.chemical_compound, 0302 clinical medicine, Smooth Muscle, 2.1 Biological and endogenous factors, Inositol, Aetiology, Receptor, 5-Trisphosphate Receptors, Neurons, Gastroenterology, Platelet-Derived Growth Factor beta, Cell biology, Survival Rate, 030220 oncology & carcinogenesis, Muscle, 030211 gastroenterology & hepatology, Smooth, Intracellular, Muscle Contraction, Biotechnology, Colon, Knockout, 1.1 Normal biological development and functioning, Clinical Sciences, IP3 receptor, Motility, PDGFRB, Cholinergic Agonists, Biology, Gut motility, 03 medical and health sciences, Underpinning research, Animals, Gastrointestinal Transit, Myocytes, Integrases, Gastroenterology & Hepatology, Animal, Endoplasmic reticulum, Intestinal Pseudo-Obstruction, Inositol trisphosphate receptor, Inositol 1, Interstitial Cells of Cajal, chemistry, Genetically Engineered Mouse, Disease Models, Carbachol, Ca2+ release channel, Digestive Diseases
وصف الملف: application/pdf
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المؤلفون: Angelo Demuro, Ian Parker, Divya Swaminathan, George D. Dickinson
المصدر: Cell Calcium
مصطلحات موضوعية: 0301 basic medicine, Biochemistry & Molecular Biology, Physiology, Xenopus, Medical Physiology, Gating, Noise analysis, Article, Fluorescence, Image (mathematics), Cell Line, Imaging, 03 medical and health sciences, 0302 clinical medicine, Imaging, Three-Dimensional, Cytosol, Rare Diseases, Ca2+ imaging, Cell Line, Tumor, Catalytic Domain, Inositol 1,4,5-Trisphosphate Receptors, Animals, Humans, Ca2+ noise, Molecular Biology, 5-Trisphosphate Receptors, Physics, Total internal reflection fluorescence microscope, Tumor, Ca(2+) puffs, Spectral density, Cell Biology, Ca2+ puffs, Inositol 1, Ca(2+) imaging, Electrophysiology, Noise, Kinetics, 030104 developmental biology, Three-Dimensional, Ca(2+) noise, Calcium, Calcium Channels, Biochemistry and Cell Biology, Biological system, 030217 neurology & neurosurgery, Cytosolic calcium
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d063eb544508aa82416185fb8a1a426
https://escholarship.org/uc/item/49t0t3kd -
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المؤلفون: Yizhi Wang, Jason P. Weick, Elizabeth K. Unger, Guoqiang Yu, Stelios Papadopoulos, Loren L. Looger, Lin Tian, Junqing Sun, Anita Bhattacharyya, Guilai Shi, Wenbin Deng, Grace O. Mizuno, Chao-Yin Chen, Yinxue Wang, Gerard Joey Broussard
المساهمون: Electrical and Computer Engineering
المصدر: Cell reports
Cell reports, vol 24, iss 2
Cell Reports, Vol 24, Iss 2, Pp 355-365 (2018)مصطلحات موضوعية: 0301 basic medicine, Adenosine, Mouse, Motor-Neurons, Down syndrome, Medical Physiology, Murine Model, Deficits, Apoptosis, Endoplasmic Reticulum, S100B, Imaging, Congenital, 0302 clinical medicine, Models, Calcium-binding protein, human IPSCs, Premovement neuronal activity, 2.1 Biological and endogenous factors, Inositol 1,4,5-Trisphosphate Receptors, Disease, Aetiology, Induced pluripotent stem cell, lcsh:QH301-705.5, 5-Trisphosphate Receptors, Calcium signaling, Neurons, 0303 health sciences, Gene knockdown, Stem Cell Research - Induced Pluripotent Stem Cell - Human, Chemistry, S100 Proteins, Cell Differentiation, astrocyte-neuron interaction, 3. Good health, Cell biology, calcium imaging, medicine.anatomical_structure, Neurological, Stem cell, Astrocyte, Intellectual and Developmental Disabilities (IDD), 1.1 Normal biological development and functioning, Induced Pluripotent Stem Cells, chemistry.chemical_element, Calcium, Models, Biological, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Calcium imaging, Imaging, Three-Dimensional, Underpinning research, medicine, Animals, Humans, Calcium Signaling, 030304 developmental biology, Stem Cell Research - Induced Pluripotent Stem Cell, Protein, astrocytes, Neurosciences, Biological, Inositol 1, Stem Cell Research, Brain Disorders, 030104 developmental biology, lcsh:Biology (General), nervous system, Dysfunction, Release, Astrocytes, Three-Dimensional, Synapses, Neuron, Biochemistry and Cell Biology, Down Syndrome, Neuroscience, 030217 neurology & neurosurgery
وصف الملف: application/pdf
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المؤلفون: Ahmed, Meftun
المساهمون: Lindström, Per, Professor
المصدر: Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine.
مصطلحات موضوعية: Cell biology, pancreatic β-cells, islets of Langerhans, glucose, Ca2+ oscillations, Ca2+ transients, potassium, ryanodine, caffeine, glucagon, cAMP, inositol 1, 5-trisphosphate, fura-2, glycine, alanine, arginine, Ca2+ channels, rats, lean mice, ob/ob mice, leptin, Cellbiologi, MEDICINE, Morphology, cell biology, pathology, MEDICIN, Morfologi, cellbiologi, patologi, medicinsk cellbiologi, Medical Cell Biology
وصف الملف: electronic
URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-1408
https://uu.diva-portal.org/smash/get/diva2:160918/FULLTEXT01.pdf
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