المؤلفون: Handoko, L., Kaczkowski, B., Hon, C. C., Lizio, M., Wakamori, M., Matsuda, T., Ito, T., Jeyamohan, P., Sato, Y., Sakamoto, K., Yokoyama, S., Kimura, Hiroshi, Minoda, A., Umehara, T.

المصدر: Epigenetics. 13(No. 4):410-431

مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Cage, Cancer Research, Lung Neoplasms, Histones, Mice, Lung Neoplasms/drug therapy/*genetics/metabolism, Carcinoma, Non-Small-Cell Lung, Transcriptional regulation, Histone code, Promoter Regions, Genetic, Azepines/*pharmacology, Triazoles/*pharmacology, Brd2, biology, Chemistry, Acetylation, Azepines, Chromatin, Cell biology, Jq1, Gene Expression Regulation, Neoplastic, Histone, Protein-Serine-Threonine Kinases/*metabolism, Transcription Initiation Site, Proto-Oncogene Proteins c-myc/genetics, Protein Serine-Threonine Kinases, Proto-Oncogene Proteins c-myc, Histone H4, Chromatin/metabolism, 03 medical and health sciences, Cell Line, Tumor, Animals, Humans, Enhancer, Molecular Biology, Transcription factor, Promoter Regions, Genetic/drug effects, Transcription Initiation Site/drug effects, Carcinoma, Non-Small-Cell Lung/drug therapy/*genetics/metabolism, Promoter, Triazoles, Acetylation/drug effects, Bromodomain, 030104 developmental biology, Histones/*chemistry/metabolism, Gene Expression Regulation, Neoplastic/drug effects, Bet, biology.protein, Cancer research, H4 hyperacetylation, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ed72bd1e8abe48f7e395d18d2ff5bbd
http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100822105

المؤلفون: Bernard Gallez, Pierre Danhier, Yu-Chih Nien, Ines Batinic-Haberle, Mark W. Dewhirst, Eui Jung Moon, Pierre Sonveaux, Paolo E. Porporato, Thies Schroeder

المساهمون: UCL - SSS/IREC/FATH - Pôle de Pharmacologie et thérapeutique, UCL - SSS/IREC - Institut de recherche expérimentale et clinique

المصدر: Proceedings of the National academy of sciences of the United States of America, Vol. 107, no. 47, p. 20477-20482 (2010)

مصطلحات موضوعية: Vascular Endothelial Growth Factor A, MAPK/ERK pathway, chemistry.chemical_compound, Mice, Extracellular Signal-Regulated MAP Kinases - metabolism, 0302 clinical medicine, Neoplasms, Extracellular Signal-Regulated MAP Kinases, chemistry.chemical_classification, 0303 health sciences, Multidisciplinary, NADPH oxidase, biology, Reverse Transcriptase Polymerase Chain Reaction, Biological Sciences, Cell Hypoxia - physiology, Immunohistochemistry, DNA Primers - genetics, Cell Hypoxia, 3. Good health, Vascular endothelial growth factor, NADPH Oxidase - metabolism, Vascular endothelial growth factor A, Hypoxia-Inducible Factor 1 - metabolism, 030220 oncology & carcinogenesis, Female, Hypoxia-Inducible Factor 1, Lactic Acid - blood, Pyruvate dehydrogenase kinase, Neoplasms - metabolism, therapy, Blotting, Western, Reactive Oxygen Species - metabolism, Enzyme-Linked Immunosorbent Assay, Protein Serine-Threonine Kinases, 03 medical and health sciences, Cell Line, Tumor, Animals, Humans, Lactic Acid, Protein-Serine-Threonine Kinases - metabolism, DNA Primers, 030304 developmental biology, Reactive oxygen species, Analysis of Variance, Tumor hypoxia, Vascular Endothelial Growth Factor A - metabolism, NADPH Oxidases, Pyruvate Dehydrogenase Acetyl-Transferring Kinase, Hyperthermia, Induced, Tumor Oxygenation, Molecular biology, Gene Expression Regulation, chemistry, Gene Expression Regulation - physiology, biology.protein, Cancer research, Reactive Oxygen Species

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c483da9bbab0739059fbe16d5b6ef826
https://hdl.handle.net/2078.1/88185

المؤلفون: Cheng Xu, Aimin Xu, Yumeng Guo, Maria Bloksgaard, Hung-Fat Tse, Weiping Han, Yu Wang, Paul M. Vanhoutte, Jo G. R. De Mey, Kangmin Yang, Andy W C Man, Bo Bai

المصدر: Scopus-Elsevier
Bai, B, Man, A W C, Yang, K, Guo, Y, Xu, C, Tse, H-F, Han, W, Bloksgaard, M, De Mey, J G R, Vanhoutte, P M, Xu, A & Wang, Y 2016, ' Endothelial SIRT1 prevents adverse arterial remodeling by facilitating HERC2-mediated degradation of acetylated LKB1 ', Oncotarget, vol. 7, no. 26, pp. 39065-39081 . https://doi.org/10.18632/oncotarget.9687
Oncotarget

مصطلحات موضوعية: 0301 basic medicine, Vascular smooth muscle, Muscle, Smooth, Vascular, blood vessel remodeling, Mice, Research Paper: Gerotarget (Focus on Aging), Muscle, Smooth, Vascular/metabolism, AMP-Activated Protein Kinase Kinases, Sirtuin 1, Guanine Nucleotide Exchange Factors, Homeostasis, Medicine, skin and connective tissue diseases, Gene knockdown, biology, Gerotarget, Ubiquitin/chemistry, Acetylation, Arteries, Protein-Serine-Threonine Kinases/metabolism, Endothelial senescence, Carotid Arteries/pathology, Ubiquitin ligase, Cell biology, Carotid Arteries, Blood vessel remodeling, medicine.anatomical_structure, Oncology, endothelial senescence, Hypertension, Nitric Oxide Synthase Type III/genetics, congenital, hereditary, and neonatal diseases and abnormalities, hypertension, LKB1, Nitric Oxide Synthase Type III, Sirtuin 1/metabolism, Endothelium, Ubiquitin-Protein Ligases, Mice, Transgenic, Protein Serine-Threonine Kinases, Vascular Remodeling, Endothelial Cells/metabolism, Endothelial activation, 03 medical and health sciences, SIRT1, 3T3-L1 Cells, Cell Line, Tumor, Humans, Animals, Guanine Nucleotide Exchange Factors/metabolism, Ubiquitin, business.industry, Endothelial Cells, Molecular medicine, Arteries/metabolism, 030104 developmental biology, Immunology, Mutagenesis, Site-Directed, biology.protein, Endothelium, Vascular, business, Protein Processing, Post-Translational, Chromatin immunoprecipitation, Endothelium, Vascular/metabolism

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f570e0ceb85d9eb326866045958e859
http://www.scopus.com/inward/record.url?eid=2-s2.0-84982903048&partnerID=MN8TOARS