نتائج البحث - "Cell Survival drug effects"

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دورية أكاديمية

Intracellular Neuroprotective Mechanisms in Neuron-Glial Networks Mediated by Glial Cell Line-Derived Neurotrophic Factor.

المؤلفون: Mitroshina, Еlena V, Mishchenko, Tatiana A, Shirokova, Olesya M, Astrakhanova, Tatiana A, Loginova, Maria M, Epifanova, Ekaterina, Babaev, Alexey A, Tarabykin, Victor S, Vedunova, Maria V

المصدر: Oxidative Medicine and Cellular Longevity, 2019, 1036907 (2019)

مصطلحات موضوعية: Glial Cell Line-Derived Neurotrophic Factor, Hypoxia-Inducible Factor 1, alpha Subunit, Neuroprotective Agents, Protein Kinase Inhibitors, EC 2.7.10.1 (Proto-Oncogene Proteins c-ret), EC 2.7.11.1 (Proto-Oncogene Proteins c-akt), SY7Q814VUP (Calcium), Animals, Calcium/metabolism, Cell Hypoxia, Cell Survival/drug effects, Cells, Cultured, Glial Cell Line-Derived Neurotrophic Factor/pharmacology, Hippocampus/cytology/drug effects/metabolism/ultrastructure, Hypoxia-Inducible Factor 1, alpha Subunit/genetics/metabolism, Mice, Mitochondria/drug effects/metabolism, Neuroprotective Agents/pharmacology, Phosphatidylinositol 3-Kinases/metabolism, Protein Kinase Inhibitors/pharmacology, Proto-Oncogene Proteins c-akt/metabolism, Proto-Oncogene Proteins c-ret/antagonists & inhibitors/metabolism, Signal Transduction/drug effects, Life sciences, Anatomy (cytology, histology, embryology...) & physiology, Sciences du vivant, Anatomie (cytologie, histologie, embryologie...) & physiologie

Relation: urn:issn:1942-0900; urn:issn:1942-0994

URL الوصول: https://orbi.uliege.be/handle/2268/303076

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Design, Optimization, and Structural Characterization of an Apoptosis-Inducing Factor Peptide Targeting Human Cyclophilin A to Inhibit Apoptosis Inducing Factor-Mediated Cell Death

المؤلفون: Biancamaria Farina, Carsten Culmsee, Amalia Mihaela Dolga, Luigi Russo, Menotti Ruvo, Nunzianna Doti, Roberto Fattorusso, Fabiola Mascanzoni, Alessandra Monti, Andrea Caporale

المساهمون: Faculty of Science and Engineering, University of Groningen, Molecular Pharmacology, Groningen Research Institute for Asthma and COPD (GRIAC), Drug Design, Russo, L., Mascanzoni, F., Farina, B., Dolga, A. M., Monti, A., Caporale, A., Culmsee, C., Fattorusso, R., Ruvo, M., Doti, N.

المصدر: Journal of Medicinal Chemistry, 64(15), 11445-11459. AMER CHEMICAL SOC

مصطلحات موضوعية: Programmed cell death, Cell Survival, Cells, Glutamic Acid, Peptide, 3d model, Cypa, Apoptosis, Dose-Response Relationship, Cyclophilin A, Mice, Structure-Activity Relationship, Cell Death/drug effects, Brain Injurie, Drug Discovery, Animals, Humans, cardiovascular diseases, Apoptosis Inducing Factor/chemical synthesis, Cells, Cultured, chemistry.chemical_classification, Cultured, biology, Cell Death, Dose-Response Relationship, Drug, Molecular Structure, Chemistry, Animal, Apoptosis/drug effects, Apoptosi, Apoptosis Inducing Factor, biology.organism_classification, In vitro, Cell biology, Cyclophilin A/antagonists & inhibitors, Glutamic Acid/metabolism, Brain Injuries, Drug Design, Molecular Medicine, Apoptosis-inducing factor, Brain Injuries/drug therapy, Drug, biological phenomena, cell phenomena, and immunity, Human, Cell Survival/drug effects

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8753f90236e54cb76eea53ccd197d5e8
https://research.rug.nl/en/publications/04f3e107-9064-406a-8ac0-abfc6105b17f

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Engineering of Biocompatible Coacervate-Based Synthetic Cells

المؤلفون: Jan C. M. van Hest, Laurynas Vasiukas, Alexander F. Mason, N. Amy Yewdall, Marleen H. M. E. van Stevendaal

المساهمون: Bio-Organic Chemistry, Institute for Complex Molecular Systems, ICMS Business Operations

المصدر: ACS Applied Materials & Interfaces
Acs Applied Materials & Interfaces., 13, 7, pp. 7879-7889
Acs Applied Materials & Interfaces., 13, 7879-7889
ACS Applied Materials and Interfaces, 13(7), 7879-7889. American Chemical Society

مصطلحات موضوعية: Polymers, Amylose/chemical synthesis, Biocompatible Materials, 02 engineering and technology, Biocompatible Materials/chemical synthesis, 01 natural sciences, Mice, complex coacervates, Materials Testing, General Materials Science, Polymers/chemical synthesis, Cell Engineering, Cells, Cultured, chemistry.chemical_classification, Cultured, Coacervate, Molecular Structure, Polymer, synthetic cells, protocells, self-assembly, 021001 nanoscience & nanotechnology, block copolymers, 0210 nano-technology, Physical Organic Chemistry, Cell Survival/drug effects, Research Article, Protocell, polycations, Materials science, Artificial Cells/chemistry, Biocompatibility, Cell Survival, Surface Properties, Cells, Nanotechnology, 010402 general chemistry, biocompatibility, Animals, Humans, Viability assay, Semipermeable membrane, Particle Size, Artificial cell, 0104 chemical sciences, RAW 264.7 Cells, chemistry, Artificial Cells, Self-assembly, Amylose, HeLa Cells

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::694704d14bd52ca89dd5598e66c54ae6
https://hdl.handle.net/https://repository.ubn.ru.nl/handle/2066/232247

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The oxidative potential of differently charged silver and gold nanoparticles on three human lung epithelial cell types

المؤلفون: Matthew S. P. Boyles, Martin Himly, Ulrike Tischler, Jiayuan Zhao, Eva Hornig, Víctor F. Puntes, Michael Riediker, Albert Duschl, Eudald Casals, Gertie Janneke Oostingh, Paul Schlinkert, Ngoc Tran

المصدر: Recercat. Dipósit de la Recerca de Catalunya
instname
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Journal of Nanobiotechnology
Recercat: Dipósit de la Recerca de Catalunya
Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Journal of Nanobiotechnology, vol. 13, no. 1, pp. 1

مصطلحات موضوعية: Silver, Cell Survival, Cytotoxicity, Biomedical Engineering, Medicine (miscellaneous), Pharmaceutical Science, Metal Nanoparticles, Nanotechnology, Bronchi/cytology, Cell Line/drug effects, Cell Membrane/drug effects, Cell Survival/drug effects, Cell-Free System, Cells, Cultured, Chitosan/chemistry, Culture Media/chemistry, Culture Media/pharmacology, Epithelial Cells/drug effects, Epithelial Cells/metabolism, Gold/pharmacology, Humans, Lung/cytology, Metal Nanoparticles/adverse effects, Metal Nanoparticles/chemistry, Oxidants/chemistry, Oxidants/pharmacology, Reactive Oxygen Species/metabolism, Silver/pharmacology, Bioengineering, Bronchi, Applied Microbiology and Biotechnology, Cell-free system, Cell Line, Chitosan, Cell membrane, chemistry.chemical_compound, medicine, Human lung epithelial cells, ROS production, Lung, A549 cell, chemistry.chemical_classification, Reactive oxygen species, Chemistry, Research, Cell Membrane, Surface charge, Epithelial Cells, respiratory system, Oxidants, Culture Media, medicine.anatomical_structure, Colloidal gold, Cell culture, Biophysics, Molecular Medicine, Nanoparticles, Gold, Reactive Oxygen Species

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d1697bc84770ff9922a3f96e3998c32
http://hdl.handle.net/2072/435898

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Dysregulation of macrophage development and phenotype in diabetic human macrophages can be rescued by Hoxa3 protein transduction

المؤلفون: Kimberly A. Mace, Edward A. McKenzie, Andrew J.M. Boulton, Tanja Torbica, Frank L. Bowling, Hadeel Al Sadoun, Salma Alrdahe

المصدر: Alrdahe, S, Al Sadoun, H, Torbica, T, McKenzie, E A, Bowling, F L, Boulton, A J M & Mace, K A 2019, ' Dysregulation of macrophage development and phenotype in diabetic human macrophages can be rescued by Hoxa3 protein transduction ', PLoS One., vol. 14, no. 10, pp. e0223980 . https://doi.org/10.1371/journal.pone.0223980, https://doi.org/10.1371/journal.pone.0223980
PLoS ONE, Vol 14, Iss 10, p e0223980 (2019)
PLoS ONE

مصطلحات موضوعية: Male, Cellular differentiation, Up-Regulation/drug effects, Pathology and Laboratory Medicine, Biochemistry, Monocytes, Endocrinology, 0302 clinical medicine, Tumor Necrosis Factors/analysis, Animal Cells, Immune Response, Cells, Cultured, Innate Immune System, Antigens, CD/genetics, Up-Regulation, 3. Good health, RUNX1, Cytokines, Medicine, Tumor necrosis factor alpha, Cellular Types, Endocrine Disorders, Immune Cells, Science, Immunology, 03 medical and health sciences, Signs and Symptoms, Antigens, CD, Manchester Institute of Biotechnology, DNA-binding proteins, Diabetes Mellitus, Genetics, Humans, Blood Cells, Macrophages, Core Binding Factor Alpha 2 Subunit/genetics, Antigens, Differentiation, Myelomonocytic/genetics, Biology and Life Sciences, Proteins, Molecular Development, Regulatory Proteins, 030104 developmental biology, Diabetes Mellitus, Type 2, chemistry, Culture Media, Conditioned, Case-Control Studies, Leukocytes, Mononuclear, Transcription Factors, Developmental Biology, 0301 basic medicine, Myeloid, Physiology, Gene Expression, Cell Maturation, White Blood Cells, chemistry.chemical_compound, Immune Physiology, Medicine and Health Sciences, Leukocytes, Mononuclear/cytology, Multidisciplinary, Cell Differentiation, Middle Aged, Recombinant Proteins, Interleukin-6/analysis, medicine.anatomical_structure, Phenotype, Core Binding Factor Alpha 2 Subunit, Tumor Necrosis Factors, Female, medicine.symptom, Research Article, Cell Survival/drug effects, Adult, Culture Media, Conditioned/chemistry, Cell Survival, Antigens, Differentiation, Myelomonocytic, Bone Marrow Cells, Inflammation, Biology, Downregulation and upregulation, Diagnostic Medicine, medicine, Gene Regulation, Recombinant Proteins/biosynthesis, Homeodomain Proteins, Interleukin-6, Macrophages/cytology, Cell Biology, ResearchInstitutes_Networks_Beacons/manchester_institute_of_biotechnology, Diabetes Mellitus, Type 2/metabolism, Metabolic Disorders, Immune System, Cancer research, Bone marrow, Homeodomain Proteins/genetics, 030215 immunology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d6ea39074a79895983e43418ef1be36
https://doi.org/10.1371/journal.pone.0223980

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Exosomal Expression of CXCR4 Targets Cardioprotective Vesicles to Myocardial Infarction and Improves Outcome after Systemic Administration

المؤلفون: Giuseppe Vassalli, Giovanni G. Camici, Sara Bolis, Elisabetta Cervio, Giuseppina Milano, Vanessa Biemmi, A. Ciullo, Tiziano Moccetti, Emanuel T. Fertig, Lucio Barile, Mihaela Gherghiceanu

المساهمون: University of Zurich, Barile, Lucio

المصدر: International Journal of Molecular Sciences, Vol 20, Iss 3, p 468 (2019)
International Journal of Molecular Sciences
Volume 20
Issue 3
International journal of molecular sciences, vol. 20, no. 3

مصطلحات موضوعية: 0301 basic medicine, Male, Benzylamines, Myocardial Infarction, 1607 Spectroscopy, Fluorescent Antibody Technique, Pharmacology, Cyclams, Cell therapy, lcsh:Chemistry, 0302 clinical medicine, Heterocyclic Compounds, intravenous injection, Myocardial infarction, lcsh:QH301-705.5, Spectroscopy, Cells, Cultured, Ejection fraction, General Medicine, Flow Cytometry, 3. Good health, Computer Science Applications, 030220 oncology & carcinogenesis, 10209 Clinic for Cardiology, Systemic administration, 1606 Physical and Theoretical Chemistry, Cardiac function curve, Receptors, CXCR4, 1503 Catalysis, Cell Survival, Blotting, Western, Ischemia, cardiac progenitor cells, 610 Medicine & health, Enzyme-Linked Immunosorbent Assay, macromolecular substances, exosomes, 11171 Cardiocentro Ticino, Catalysis, Article, Inorganic Chemistry, 03 medical and health sciences, Animals, Cell Survival/drug effects, Cell Survival/genetics, Cell Survival/physiology, Chemokine CXCL12/genetics, Chemokine CXCL12/metabolism, Cryoelectron Microscopy, Exosomes/metabolism, Heterocyclic Compounds/therapeutic use, Humans, Myocardial Infarction/genetics, Myocardial Infarction/metabolism, Myocardial Infarction/therapy, RNA, Messenger/genetics, RNA, Messenger/metabolism, Rats, Rats, Wistar, Receptors, CXCR4/antagonists & inhibitors, Receptors, CXCR4/genetics, Receptors, CXCR4/metabolism, CXCR4, 1312 Molecular Biology, 1706 Computer Science Applications, medicine, RNA, Messenger, Physical and Theoretical Chemistry, Progenitor cell, Molecular Biology, 1604 Inorganic Chemistry, business.industry, Organic Chemistry, fungi, medicine.disease, Chemokine CXCL12, carbohydrates (lipids), enzymes and coenzymes (carbohydrates), 030104 developmental biology, lcsh:Biology (General), lcsh:QD1-999, business, Reperfusion injury, 1605 Organic Chemistry

وصف الملف: application/pdf; Exosomal_Expression_of_CXCR4.pdf - application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfd80ce773ca01cb03b66b6207e52de7
https://www.mdpi.com/1422-0067/20/3/468

Find this article in full text from ProQuest

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Sawhorse-type diruthenium tetracarbonyl complexes containing porphyrin-derived ligands as highly selective photosensitizers for female reproductive cancer cells

المؤلفون: Mathieu Auzias, Kentaro Yamaguchi, Frédéric Schmitt, Petr Štěpnička, Georg Süss-Fink, Yoshihisa Sei, Lucienne Juillerat-Jeanneret, Bruno Therrien

المصدر: Journal of Biological Inorganic Chemistry, vol. 14, no. 5, pp. 693-701

مصطلحات موضوعية: Porphyrins, Antineoplastic Agents/chemical synthesis, Antineoplastic Agents/chemistry, Carcinoma/drug therapy, Cell Line, Tumor, Cell Survival/drug effects, Cells, Cultured, Electrochemistry, Female, Fibroblasts/cytology, Fibroblasts/drug effects, Humans, Molecular Structure, Organometallic Compounds/chemical synthesis, Organometallic Compounds/chemistry, Ovarian Neoplasms/drug therapy, Photosensitizing Agents/chemical synthesis, Photosensitizing Agents/chemistry, Porphyrins/chemical synthesis, Porphyrins/chemistry, Spectrum Analysis, Uterine Cervical Neoplasms/drug therapy, Stereochemistry, Cell Survival, Uterine Cervical Neoplasms, Antineoplastic Agents, Biochemistry, Inorganic Chemistry, HeLa, chemistry.chemical_compound, LNCaP, medicine, Organometallic Compounds, Photosensitizer, Cytotoxicity, Ovarian Neoplasms, Photosensitizing Agents, biology, Carcinoma, Cancer, Fibroblasts, medicine.disease, biology.organism_classification, Fluorescence, Porphyrin, chemistry, Cell culture

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::094070ade7b16f4bcf793b5fceb1e46e
http://doc.rero.ch/record/317633/files/775_2009_Article_482.pdf

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Thrombin modifies growth, proliferation and apoptosis of human colon organoids: a protease-activated receptor 1- and protease-activated receptor 4-dependent mechanism

المؤلفون: Sébert, Morgane, Denadai‐Souza, Alexandre, Quaranta, Muriel, Racaud‐Sultan, Claire, Chabot, Sophie, Lluel, Philippe, Monjotin, Nicolas, Alric, Laurent, Portier, Guillaume, Kirzin, Sylvain, Bonnet, Delphine, Ferrand, Audrey, Vergnolle, Nathalie

المساهمون: Institut de Recherche en Santé Digestive (IRSD ), Institut National de la Recherche Agronomique (INRA)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Ecole Nationale Vétérinaire de Toulouse (ENVT), Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre de Physiopathologie Toulouse Purpan ex IFR 30 et IFR 150 (CPTP), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS), Urosphère SAS, UROsphere S.A.S., Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Faculte des Sciences Pharmaceutiques, Centre de Recherche Pierre Fabre, Hôpital Purpan [Toulouse], CHU Toulouse [Toulouse], Chirurgie Générale et Digestive [Purpan], CHU Toulouse [Toulouse]-Hôpital Purpan [Toulouse], Centre de Physiopathologie Toulouse Purpan (CPTP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Centre de Recherche Pierre Fabre (Centre de R&D Pierre Fabre), PIERRE FABRE, European Project: 310973,EC:FP7:ERC,ERC-2012-StG_20111109,PIPE(2013), Université de Toulouse (UT)-Université de Toulouse (UT)-Ecole Nationale Vétérinaire de Toulouse (ENVT), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)

المصدر: British Journal of Pharmacology
British Journal of Pharmacology, Wiley, 2018, 175 (18), pp.3656-3668. ⟨10.1111/bph.14430⟩
British Journal of Pharmacology, 2018, 175 (18), pp.3656-3668. ⟨10.1111/bph.14430⟩

مصطلحات موضوعية: Organoids / cytology, Cell Survival / drug effects, Receptors Thrombin / metabolism, Cell Survival, Colon, EPITHELIUM, Apoptosis, Receptor PAR-1 / metabolism, [SDV.BC.BC]Life Sciences [q-bio]/Cellular Biology/Subcellular Processes [q-bio.SC], Apoptosis / drug effects, Organoids / drug effects, CELL-PROLIFERATION, CLONING, ANTAGONISTS, INJURY, Humans, Receptor, PAR-1, Pharmacology & Pharmacy, Cells, Cultured, Cell Proliferation, Colon / cytology, Science & Technology, Thrombin, ABERRANT EXPRESSION, Research Papers, CONCISE GUIDE, CANCER, Thrombin / pharmacology, Organoids, Organoids / growth & development, Colon / drug effects, [SDV.SP.PHARMA]Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology, Cell Proliferation / drug effects, Receptors, Thrombin, Cells Cultured, Life Sciences & Biomedicine, STEM-CELLS, Research Paper, INFLAMMATORY-BOWEL-DISEASE