نتائج البحث - "activity profiles"

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دورية أكاديمية

Computer-Aided Estimation of Biological Activity Profiles of Drug-Like Compounds Taking into Account Their Metabolism in Human Body

المؤلفون: Dmitry A. Filimonov, Anastassia V. Rudik, Alexander V. Dmitriev, Vladimir V. Poroikov

المصدر: International Journal of Molecular Sciences, Vol 21, Iss 20, p 7492 (2020)

مصطلحات موضوعية: drug-like compounds, biological activity profiles, metabolism, computer-aided predictions, Biology (General), QH301-705.5, Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1422-0067/21/20/7492; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067

URL الوصول: https://doaj.org/article/cc3c28e29bdb4016b57d900eec9a4fcf

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Human Cytosolic and Mitochondrial Serine Hydroxymethyltransferase Isoforms in Comparison: Full Kinetic Characterization and Substrate Inhibition Properties

المؤلفون: Anna Barile, Martino L. di Salvo, Caterina Nardella, Angela Tramonti, Roberto Contestabile, Francesca Cutruzzolà

المصدر: Biochemistry (Easton) 57 (2018): 6984–6996. doi:10.1021/acs.biochem.8b01074
info:cnr-pdr/source/autori:Tramonti, Angela; Nardella, Caterina; di Salvo, Martino L.; Barile, Anna; Cutruzzola, Francesca; Contestabile, Roberto/titolo:Human Cytosolic and Mitochondrial Serine Hydroxymethyltransferase Isoforms in Comparison: Full Kinetic Characterization and Substrate Inhibition Properties/doi:10.1021%2Facs.biochem.8b01074/rivista:Biochemistry (Easton)/anno:2018/pagina_da:6984/pagina_a:6996/intervallo_pagine:6984–6996/volume:57

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4811caf10dfc2ee9ddf9078173b0878d
https://pubmed.ncbi.nlm.nih.gov/30500180

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Computer-Aided Estimation of Biological Activity Profiles of Drug-Like Compounds Taking into Account Their Metabolism in Human Body

المؤلفون: Vladimir Poroikov, A. V. Rudik, Alexander V. Dmitriev, Dmitry Filimonov

المصدر: International Journal of Molecular Sciences
Volume 21
Issue 20
International Journal of Molecular Sciences, Vol 21, Iss 7492, p 7492 (2020)

مصطلحات موضوعية: Drug, media_common.quotation_subject, In silico, computer-aided predictions, Computational biology, Article, Catalysis, lcsh:Chemistry, drug-like compounds, Inorganic Chemistry, Structure-Activity Relationship, 03 medical and health sciences, 0302 clinical medicine, Biotransformation, Drug Discovery, Humans, Computer Simulation, Physical and Theoretical Chemistry, lcsh:QH301-705.5, Molecular Biology, Spectroscopy, Organism, 030304 developmental biology, media_common, Active ingredient, 0303 health sciences, Chemistry, Organic Chemistry, Reproducibility of Results, Biological activity, General Medicine, Metabolism, Computer Science Applications, biological activity profiles, lcsh:Biology (General), lcsh:QD1-999, Drug Design, 030220 oncology & carcinogenesis, Molecular targets, Computer-Aided Design, metabolism, Software

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c72cf1d24b6451a8bcad54e0e3ba6da8
https://doi.org/10.3390/ijms21207492

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Reduced levels of NADH-dependent glutamate dehydrogenase decrease the glutamate content of ripe tomato fruit but have no effect on green fruit or leaves

المؤلفون: Ronan Sulpice, Gisela Ferraro, Matilde Elvira D'angelo, Mark Stitt, Estela M. Valle

المصدر: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

مصطلحات موضوعية: Physiology, enzyme-activity profiles, Plant Science, Genetically modified crops, Mitochondrion, purl.org/becyt/ford/1 [https], chemistry.chemical_compound, Solanum lycopersicum, Gdh Silencing, Gene Expression Regulation, Plant, Plant Proteins, chemistry.chemical_classification, aspartate, biology, plants, food and beverages, Ripening, Plants, Genetically Modified, Mitochondria, mature fruit, Amino Acid, Biochemistry, Organ Specificity, Ketoglutaric Acids, Mature Fruit, metabolizing enzymes, CIENCIAS NATURALES Y EXACTAS, amino acid, gdh silencing, Otras Ciencias Biológicas, cv micro-tom, amino-acids, Glutamic Acid, Artificial Microrna, Fructose, Ciencias Biológicas, Species Specificity, artificial microrna, gaba accumulation, Botany, Gene Silencing, artificial micrornas, gene, purl.org/becyt/ford/1.6 [https], Aspartic Acid, Glutamate dehydrogenase, nitrogen assimilation, Metabolism, biology.organism_classification, ripening, Plant Leaves, MicroRNAs, arabidopsis, Glucose, Enzyme, Aspartate, chemistry, Fruit, Solanum, Glutamate Dehydrogenase (NADP+), NADP

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d43a1746dbea83c5c4a4eacfb2dcbff9
https://doi.org/10.1093/jxb/erv150

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Metabolising old soil carbon: simply a matter of simple organic matter?

المؤلفون: Naoise Nunan, F. Changey, Valérie Pouteau, Stéphanie Giusti-Miller, Anke M. Herrmann, Thomas Kätterer, Philippe Mora, Thomas Z. Lerch

المساهمون: Institut d'écologie et des sciences de l'environnement de Paris (iEES), Centre National de la Recherche Scientifique (CNRS)-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Recherche Agronomique (INRA), Institut d'écologie et des sciences de l'environnement de Paris (iEES Paris), Institut National de la Recherche Agronomique (INRA)-Sorbonne Université (SU)-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)-Centre National de la Recherche Scientifique (CNRS), Department of Ecology, Swedish University of Agricultural Sciences (SLU), CNRS (INSU) under EC2CO programme (Action Thematique: Cytrix - 'Vulnerabilite du carbone stable des sols aux changements climatiques'), Swedish Research Council Formas [2012-530], Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Institut National de la Recherche Agronomique (INRA)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)-Centre National de la Recherche Scientifique (CNRS)

المصدر: Soil Biology and Biochemistry
Soil Biology and Biochemistry, Elsevier, 2015, 88, pp.128-136. ⟨10.1016/j.soilbio.2015.05.018⟩
Soil Biology and Biochemistry, 2015, 88, pp.128-136. ⟨10.1016/j.soilbio.2015.05.018⟩