المؤلفون: Georgios Dryllis, Elena E. Solomou, Andreas Giannopoulos, Nefeli Giannakopoulou, Panayiotis Panayiotidis, Sevastianos Hatzidavid, Nora-Athina Viniou, Vasiliki Pappa, Theodoros Loupis, Christina-Nefeli Kontandreopoulou, Ioannis Kotsianidis, Katerina Zoi, Athanasios Galanopoulos, Maria Dimou, Argiris Symeonidis, Panagiotis T. Diamantopoulos

المصدر: Leukemia & Lymphoma. 63:729-737

مصطلحات موضوعية: Cancer Research, Ribonucleoside Diphosphate Reductase, Methylation, Splicing factor, Bone Marrow, Ribonucleotide Reductases, medicine, Humans, RNA, Messenger, Gene, chemistry.chemical_classification, business.industry, Promoter, Hematology, Prognosis, medicine.anatomical_structure, Enzyme, Ribonucleotide reductase, Oncology, chemistry, Myelodysplastic Syndromes, Azacitidine, Cancer research, Biomarker (medicine), Bone marrow, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bf78e0c10f721d04b01226576060950
https://doi.org/10.1080/10428194.2021.1998484

المؤلفون: Yury Kutin, Müge Kasanmascheff, Shari L. Meichsner

المصدر: Angewandte Chemie (International Ed. in English)

مصطلحات موضوعية: Free Radicals, Stereochemistry, 010402 general chemistry, ribonucleotide reductase, 01 natural sciences, Catalysis, Cofactor, law.invention, chemistry.chemical_compound, Biosynthesis, law, In vivo, Ribonucleotide Reductases, Escherichia coli, Biophysics | Hot Paper, Electron paramagnetic resonance, Research Articles, chemistry.chemical_classification, metalloenzymes, biology, 010405 organic chemistry, Electron Spin Resonance Spectroscopy, General Chemistry, General Medicine, 0104 chemical sciences, Amino acid, Enzyme, Ribonucleotide reductase, chemistry, biology.protein, Tyrosine, tyrosyl radicals, DNA, unnatural amino acids, Research Article, EPR spectroscopy

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b49d3fb8bca21a110feea3f6bf0daa3
http://europepmc.org/articles/PMC8453577

المؤلفون: Elisa Tomat, Rohit Kumar Sharma, Nahiara Alicea, Sofia C. Pérez Otero, Martin Kowaleff, Liz Hernandez-Matias, Eman A. Akam, Andrei V. Astashkin, Kavita Gaur, Sergio A. Loza-Rosas, Josué A. Benjamín-Rivera, Arthur D. Tinoco, Anthony V Washington, Alexandra M. Vázquez Salgado, Israel Rodríguez

المصدر: JACS Au, Vol 1, Iss 6, Pp 865-878 (2021)
Jacs Au

مصطلحات موضوعية: chemistry.chemical_classification, 0303 health sciences, ribonucleotide reductase inhibition, Chemistry, metal-based anticancer strategy, Protein subunit, DNA replication, Cell cycle, 010402 general chemistry, 01 natural sciences, Article, 0104 chemical sciences, 03 medical and health sciences, Enzyme, Ribonucleotide reductase, intracellular iron(III) transmetalation, Biochemistry, Transferrin, titanium(IV) binding of nucleotides, Titanium(IV) chemical transferrin mimetic complexes, Nucleotide, QD1-999, Intracellular, 030304 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10db648cb2073e34128f051b0b72e28e
https://doi.org/10.1021/jacsau.1c00078

المؤلفون: JoAnne Stubbe, Marina Bennati, Fabian Hecker

المصدر: Journal of the American Chemical Society
The Journal of the American Chemical Society

مصطلحات موضوعية: Free Radicals, Electrons, Oxygen Isotopes, 010402 general chemistry, Photochemistry, 01 natural sciences, Biochemistry, Catalysis, Electron Transport, Electron transfer, Colloid and Surface Chemistry, Ribonucleotide Reductases, Escherichia coli, Molecule, Hyperfine structure, Density Functional Theory, chemistry.chemical_classification, Chemistry, Communication, Electron Spin Resonance Spectroscopy, Water, General Chemistry, Resonance (chemistry), 0104 chemical sciences, Ribonucleotide reductase, Enzyme, Electron nuclear double resonance spectroscopy, Tyrosine, Proton-coupled electron transfer

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::989b959e96a086b3e6c60a8190625b66
https://doi.org/10.1021/jacs.1c01359

المؤلفون: Stephen D. Larson, McKenzie Carter, Galadriel Hovel-Miner

المصدر: Parasitology

مصطلحات موضوعية: 0301 basic medicine, melarsoprol, T. brucei, 030106 microbiology, trypanothione, Trypanothione, γ-glutamylcysteine synthetase, Melarsoprol, Biology, ribonucleotide reductase, 03 medical and health sciences, chemistry.chemical_compound, Biosynthesis, Eflornithine, medicine, Trypanosomatids, chemistry.chemical_classification, DNA synthesis, fexinidazole, Cell cycle, Antitrypanosomal drugs, 030104 developmental biology, Infectious Diseases, Ribonucleotide reductase, Enzyme, Biochemistry, chemistry, Animal Science and Zoology, Parasitology, cell cycle, medicine.drug, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8c0fa1aa30cde39a40b6d002e8d43b1
http://europepmc.org/articles/PMC8292159

المؤلفون: Daniela Göhringer, Clemens Richert, Carolina Sánchez Rico, Maren Bechthold, Jennifer Bremer, Helmut Griesser, Olivia Doppleb

المصدر: Chemistry (Weinheim an Der Bergstrasse, Germany)

مصطلحات موضوعية: chemistry.chemical_classification, amino acids, prebiotic chemistry, Magnetic Resonance Spectroscopy, Dipeptide, Ribonucleotide, Full Paper, Stereochemistry, Organic Chemistry, Hot Paper, Stereoisomerism, General Chemistry, Nuclear magnetic resonance spectroscopy, Full Papers, stereoselectivity, Catalysis, Amino acid, chemistry.chemical_compound, Residue (chemistry), chemistry, peptides, RNA, Racemic mixture, Nucleotide, Homochirality

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb84dfd24f31335e51e276e93fbbc19b
https://doi.org/10.1002/chem.202101630

المؤلفون: Pavel Majer, Rana Rais, Kathryn M. Lemberg, Ying Wu, Lukáš Tenora, Barbara S. Slusher, Sadakatali S Gori, Vijayabhaskar Veeravalli, Ranjeet Prasad Dash, Qi Sun, Arindom Pal, Jesse Alt, Joanna Marie H. Aguilar

المصدر: Curr Drug Metab

مصطلحات موضوعية: Ribonucleotide, Glutamine, Clinical Biochemistry, Glycine, Biomarkers, Pharmacological, Mass Spectrometry, Article, Mice, Metabolomics, Drug Development, Pharmacokinetics, Neoplasms, Biomarkers, Tumor, Animals, Distribution (pharmacology), Purine metabolism, Pharmacology, chemistry.chemical_classification, Ribonucleotides, Prodrug, Enzyme, chemistry, Cancer research, Metabolic Networks and Pathways, Chromatography, Liquid

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5f260c7c3f8ca5b5f00e67301281a76
https://doi.org/10.2174/1389200222666210831125041

المؤلفون: David D. Shock, Samuel H. Wilson, Lalith Perera, Joonas A. Jamsen, William A. Beard, Akira Sassa

المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Nature Communications

مصطلحات موضوعية: Models, Molecular, Genome instability, Ribonucleotide, DNA Repair, DNA repair, DNA polymerase, Science, General Physics and Astronomy, DNA-Directed DNA Polymerase, Article, General Biochemistry, Genetics and Molecular Biology, Cytosine, Catalytic Domain, Humans, DNA Breaks, Double-Stranded, Nucleotide, heterocyclic compounds, Polymerase, Cancer, X-ray crystallography, chemistry.chemical_classification, Manganese, Multidisciplinary, biology, Adenine, Mutagenesis, Deoxyguanine Nucleotides, General Chemistry, Ribonucleotides, Double Strand Break Repair, Kinetics, chemistry, Enzyme mechanisms, biology.protein, Biophysics, Calcium, Oxidation-Reduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d79dc7516fa0a4c7d26eba6116ea1814
https://doaj.org/article/1da597dd861e4c449ac7230ac323f30d

المؤلفون: Catherine L. Drennan, Alexander T. Taguchi, Gyunghoon Kang, JoAnne Stubbe

المصدر: Science

مصطلحات موضوعية: 0301 basic medicine, Ribonucleotide, Protein Conformation, Stereochemistry, Protein subunit, 010402 general chemistry, 01 natural sciences, Article, 03 medical and health sciences, Protein structure, Oxidoreductase, Catalytic Domain, Ribonucleotide Reductases, Nucleotide, chemistry.chemical_classification, Multidisciplinary, biology, Escherichia coli Proteins, Cryoelectron Microscopy, Active site, 0104 chemical sciences, 030104 developmental biology, Enzyme, Ribonucleotide reductase, chemistry, Biocatalysis, biology.protein, Tyrosine, Holoenzymes

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08e43acaafa03ad27945f3ae178c547c
https://doi.org/10.1126/science.aba6794

المؤلفون: Liya Wang, Staffan Eriksson, Ren Sun

المصدر: BMC Molecular and Cell Biology, Vol 21, Iss 1, Pp 1-10 (2020)
BMC Molecular and Cell Biology

مصطلحات موضوعية: 0301 basic medicine, Mitochondrial DNA, Mitochondrial disease, Mitochondrion, Mitochondrial DNA depletion, DNA, Mitochondrial, Thymidine Kinase, dTMP synthesis, mtDNA, Rats, Sprague-Dawley, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Cytosol, Ribonucleotide Reductases, RNR, medicine, Thymidine Monophosphate, Thymidine kinase 2, Animals, lcsh:QH573-671, Muscle, Skeletal, Molecular Biology, Ribonucleotide reductase, chemistry.chemical_classification, Chemistry, lcsh:Cytology, Skeletal muscle, Brain, Heart, Cell Biology, medicine.disease, Mitochondria, Rats, 030104 developmental biology, Enzyme, medicine.anatomical_structure, Biochemistry, Liver, Organ Specificity, p53R2, Thymidylate synthase, Thymidine, Cell and Molecular Biology, 030217 neurology & neurosurgery, Spleen, Research Article

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae9897b2e660ace82d141fde1636addc
http://link.springer.com/article/10.1186/s12860-020-00272-3