نتائج البحث - "Insulin secretion"

1

Low-Density Lipoprotein Cholesterol Is Associated With Insulin Secretion

المؤلفون: Andreas Peter, Hans-Ulrich Häring, Martin Heni, Corinna Dannecker, Norbert Stefan, Andreas L. Birkenfeld, Julia Hummel, Robert Wagner, Andreas Vosseler, Andreas Fritsche

المصدر: J. Clin. Endocrinol. Metab. 106, 1576-1584 (2021)
The Journal of Clinical Endocrinology and Metabolism

مصطلحات موضوعية: Blood Glucose, Male, 0301 basic medicine, insulin secretion, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Clinical Biochemistry, Type 2 diabetes, Biochemistry, Cohort Studies, chemistry.chemical_compound, 0302 clinical medicine, Endocrinology, Germany, Insulin-Secreting Cells, Insulin, Fasting, insulin clearance, LDL cholesterol, Female, lipids (amino acids, peptides, and proteins), type 2 diabetes, AcademicSubjects/MED00250, Adult, medicine.medical_specialty, 030209 endocrinology & metabolism, Context (language use), Glucagon, Ldl Cholesterol, Insulin Clearance, Insulin Secretion, Type 2 Diabetes, 03 medical and health sciences, Diabetes mellitus, Internal medicine, medicine, Humans, Pancreas, Clinical Research Articles, Glycemic, business.industry, Cholesterol, Biochemistry (medical), Cholesterol, LDL, Glucose Tolerance Test, medicine.disease, 030104 developmental biology, Diabetes Mellitus, Type 2, chemistry, Insulin Resistance, business, Lipoprotein

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bd14b3a7d0dde78514c3ceeac5988c3
https://doi.org/10.1210/clinem/dgab147

2

Glucagon Potentiates Insulin Secretion Via β-Cell GCGR at Physiological Concentrations of Glucose

المؤلفون: Yulin Zhang, Xiaohong Peng, Wenzhen Zhu, Yanmei Liu, Chengsheng Han, Jin Zhang, Liangyi Chen, Sohum Mehta, Guoyi Yang

المصدر: Cells, Vol 10, Iss 2495, p 2495 (2021)
Cells
Volume 10
Issue 9

مصطلحات موضوعية: Male, medicine.medical_specialty, endocrine system, QH301-705.5, Cell, β-cells, Stimulation, Glucagon, Article, Glucagon-Like Peptide-1 Receptor, Adenylyl cyclase, Mice, chemistry.chemical_compound, α-cells, Glucagon-Like Peptide 1, cAMP, Insulin-Secreting Cells, Internal medicine, Glucose Intolerance, Insulin Secretion, Receptors, Glucagon, medicine, Animals, Insulin, Glucose homeostasis, Biology (General), Receptor, glucose-stimulated insulin secretion, GLP-1R, Mice, Knockout, GCGR, Chemistry, digestive, oral, and skin physiology, General Medicine, Mice, Inbred C57BL, Glucose, Endocrinology, medicine.anatomical_structure, glucagon, Knockout mouse, hormones, hormone substitutes, and hormone antagonists, Signal Transduction, Hormone

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URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fac5cbc8e8f74cd5f8fad7fff7e0679
https://www.mdpi.com/2073-4409/10/9/2495

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3

SGLT2 is not expressed in pancreatic α- and β-cells, and its inhibition does not directly affect glucagon and insulin secretion in rodents and humans

المساهمون: Université Catholique de Louvain = Catholic University of Louvain (UCL), Boehringer Ingelheim Pharma GmbH & Co. KG, University of Geneva [Switzerland], Addenbrooke's Hospital, Cambridge University NHS Trust, Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Lausanne University Hospital, IRCCS Ospedale San Raffaele [Milan, Italy], Chae, Heeyoung, Augustin, Robert, Gatineau, Eva, Mayoux, Eric, Bensellam, Mohammed, Antoine, Nancy, Khattab, Fira, Lai, Bao-Khanh, Brusa, Davide, Stierstorfer, Birgit, Klein, Holger, Singh, Bilal, Ruiz, Lucie, Pieper, Michael, Mark, Michael, Herrera, Pedro L, Gribble, Fiona M, Reimann, Frank, Wojtusciszyn, Anne, Broca, Christophe, Rita, Nano, Piemonti, Lorenzo, Gilon, Patrick, Gribble, Fiona [0000-0002-4232-2898], Reimann, Frank [0000-0001-9399-6377], Apollo - University of Cambridge Repository

المصدر: Molecular Metabolism
Molecular metabolism, vol. 42, pp. 101071
Molecular metabolism
Molecular metabolism, Elsevier, 2020, 42, pp.101071. ⟨10.1016/j.molmet.2020.101071⟩
Molecular Metabolism (2020) P. 101071
Molecular Metabolism, Vol 42, Iss, Pp 101071-(2020)

مصطلحات موضوعية: 0301 basic medicine, Blood Glucose, medicine.medical_treatment, IC50, half maximal inhibitory concentration, SGLT2i, sodium-glucose cotransporter 2 inhibitors, MESH: Insulin Secretion, MESH: Glucosides, MESH: Insulin-Secreting Cells, chemistry.chemical_compound, Mice, αMG, α-methyl-D-glucopyranoside, EGP, endogenous glucose production, 0302 clinical medicine, Glucosides, Glucagon-Like Peptide 1, Insulin-Secreting Cells, FACS, fluorescence-activated cell sorting, Insulin Secretion, Insulin, ddc:576.5, MESH: Animals, Dapagliflozin, geography.geographical_feature_category, Chemistry, MESH: Glucagon, BW, body weight, Diabetes, SGLT2 inhibitor, MESH: Pancreas, [SDV.MHEP.EM]Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism, Islet, 3. Good health, SGLT, sodium-glucose cotransporter, MESH: Glucose, MESH: Sodium-Glucose Transporter 2, No direct effect of SGLT2i on α- and β-cells, MESH: Sodium-Glucose Transporter 2 Inhibitors, Ketone bodies, Original Article, medicine.medical_specialty, lcsh:Internal medicine, endocrine system, MESH: Rats, 030209 endocrinology & metabolism, MESH: Insulin, Glucagon, 03 medical and health sciences, Islets of Langerhans, Gliflozins, TPM, transcripts per million, Sodium-Glucose Transporter 2, G, glucose, In vivo, Internal medicine, Empagliflozin, medicine, MESH: Benzhydryl Compounds, Animals, Humans, Benzhydryl Compounds, lcsh:RC31-1245, Molecular Biology, MESH: Mice, Pancreas, Sodium-Glucose Transporter 2 Inhibitors, geography, MESH: Humans, MESH: Islets of Langerhans, Glucose transporter, MESH: Glucagon-Like Peptide 1, Cell Biology, Rats, 030104 developmental biology, Endocrinology, Glucose, Glucagon-Secreting Cells, MESH: Blood Glucose, MESH: Glucagon-Secreting Cells, Cmax, maximum serum concentration, diabetes, glucagon, insulin