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المؤلفون: Pierre Maechler, Gaelle Chaffard, Marina Shamini Casimir
المصدر: Pflügers Archiv, Vol. 471, No 2 (2019) pp. 337-345
مصطلحات موضوعية: 0301 basic medicine, Antioxidant, Long term treatment, Physiology, medicine.medical_treatment, Clinical Biochemistry, Pharmacology, Resveratrol, Antioxidants, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Cell Line, Tumor, Insulin-Secreting Cells, Physiology (medical), Insulin Secretion, medicine, Animals, Insulin, Receptor, Insulin secretion, ddc:612, Pancreatic beta-cell, Mercaptoethanol, Chemistry, INS-1E cells, Cell Differentiation, Phenotype, Molecular medicine, Rats, Glucose, 030104 developmental biology, Beta cell, 030217 neurology & neurosurgery
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المؤلفون: Monica Losada-Barragán
المصدر: Molecular and cellular biochemistry. 476(8)
مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, medicine.medical_treatment, Clinical Biochemistry, Context (language use), Type 2 diabetes, Biology, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Insulin resistance, Internal medicine, Insulin-Secreting Cells, Insulin Secretion, medicine, Animals, Humans, Insulin, Molecular Biology, Fructose, Cell Biology, General Medicine, Nutrients, medicine.disease, Obesity, 030104 developmental biology, Endocrinology, chemistry, 030220 oncology & carcinogenesis, Homeostasis, Hormone
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المؤلفون: Peter M. Jones, Vanya Nikolova, Catherine Williamson, Elena Bellafante, Hanns-Ulrich Marschall, Anita Banerjee, Luiza Borges Manna, Saraid McIlvride, Marcus Martineau, Mavis Machirori, Jenny Chambers, Kevin Murphy, Kristina Schoonjans, Hei Man Fan
المصدر: Bellafante, E, Mcilvride, S, Nikolova, V, Fan, H M, Borges Manna, L, Chambers, J, MacHirori, M, Banerjee, A, Murphy, K, Martineau, M G, Schoonjans, K, Marschall, H-U, Jones, P & Williamson, C 2020, ' Maternal glucose homeostasis is impaired in mouse models of gestational cholestasis ', Scientific Reports .
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)مصطلحات موضوعية: 0301 basic medicine, Physiology, Metabolic disorders, lcsh:Medicine, Receptors, Cytoplasmic and Nuclear, Receptors, G-Protein-Coupled, Impaired glucose tolerance, chemistry.chemical_compound, 0302 clinical medicine, Risk Factors, Insulin-Secreting Cells, Glucose homeostasis, Homeostasis, differential regulation, lcsh:Science, Multidisciplinary, Deoxycholic acid, G protein-coupled bile acid receptor, beta-cells, 030211 gastroenterology & hepatology, Female, Maternal Inheritance, pregnancy, Cholestasis of pregnancy, intrahepatic cholestasis, medicine.medical_specialty, Lithocholic acid, mice, Cholestasis, Intrahepatic, Article, Bile Acids and Salts, 03 medical and health sciences, fxr, Cholestasis, Internal medicine, Glucose Intolerance, medicine, Animals, Humans, business.industry, lcsh:R, Cholic acid, medicine.disease, Pregnancy Complications, Diabetes, Gestational, Disease Models, Animal, 030104 developmental biology, Endocrinology, Glucose, bile-acid receptor, chemistry, lcsh:Q, farnesoid-x-receptor, activation, Insulin Resistance, business, insulin-secretion
وصف الملف: application/vnd.openxmlformats-officedocument.wordprocessingml.document
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20460c6ca2d593d12a2101995ef0c260
https://kclpure.kcl.ac.uk/portal/en/publications/maternal-glucose-homeostasis-is-impaired-in-mouse-models-of-gestational-cholestasis(3e22c11b-198e-4314-8fae-984cc0df980e).html -
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المؤلفون: Chun-Kwok Wong, Xiao Yu Tian, Dandan Mao, Di Mao, Clara Bik-San Lau, Sze Wan Hung, Juliana C.N. Chan, Wing Hung Tam, Ronald C.W. Ma, Xing Ming, Huanyi Cao, Chi Chiu Wang, Elaine Chow, Alice P.S. Kong, Paul K.S. Chan, Joshua Jing Xi Li, Heung Man Lee, Guy A. Rutter
المصدر: J Biol Chem
مصطلحات موضوعية: 0301 basic medicine, Interleukin-1beta, Inflammation, IκB kinase, Pharmacology, Biochemistry, Cell Line, 03 medical and health sciences, chemistry.chemical_compound, Mice, In vivo, Diabetes mellitus, Insulin-Secreting Cells, Insulin Secretion, medicine, Animals, Obesity, Molecular Biology, geography, geography.geographical_feature_category, 030102 biochemistry & molecular biology, Chemistry, Plant Extracts, Ophiopogon, Transcription Factor RelA, NF-κB, Cell Biology, medicine.disease, Islet, Dietary Fats, I-kappa B Kinase, Plant Tubers, 030104 developmental biology, medicine.anatomical_structure, medicine.symptom, Beta cell, Pancreas
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11a01f4a484be6b7c014547dcbbd4276
https://pubmed.ncbi.nlm.nih.gov/32605924 -
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المؤلفون: Mingxia Yuan, Rongrong Xie, Jin-Kui Yang, Fengran Xiong, Han Shen, Jing Lu, Qi Li
المصدر: FASEB journal : official publication of the Federation of American Societies for Experimental BiologyREFERENCES. 34(11)
مصطلحات موضوعية: 0301 basic medicine, Male, medicine.medical_specialty, Thapsigargin, medicine.medical_treatment, Cell, Palmitic Acid, Apoptosis, Protective Agents, Biochemistry, Calcium in biology, Impaired glucose tolerance, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, Internal medicine, Insulin-Secreting Cells, Insulin Secretion, Genetics, medicine, Animals, Insulin, Enzyme Inhibitors, Molecular Biology, Mice, Knockout, Endoplasmic reticulum, medicine.disease, Endoplasmic Reticulum Stress, Ether-A-Go-Go Potassium Channels, Mice, Inbred C57BL, 030104 developmental biology, Endocrinology, medicine.anatomical_structure, Glucose, chemistry, Unfolded protein response, Calcium, Female, 030217 neurology & neurosurgery, Biotechnology
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المؤلفون: Theodoros Stylianides, Fabien Alpy, Peter I. Benke, Alexandra Piunti, Victoria Salem, Michele Solimena, Alejandra Tomas, David J. Hodson, Andrew Cakebread, Andreas Müller, Kate J. Heesom, Nur Shabrina Amirruddin, Federico Torta, Isabelle Leclerc, Leena Haataja, Peter Arvan, Timothy J. Pullen, Annie C. H. Fung, Linford J.B. Briant, Kaiying Cheng, Gaelle Carrat, Alice P.S. Kong, Dale B. Wigley, Philip A. Lewis, Richard B. Sessions, Elizabeth Haythorne, Mutian Huang, Adrian Kee Keong Teo, Guy A. Rutter, Eleni Georgiadou, Walter Distaso
المساهمون: Imperial College London, University of Michigan Medical School [Ann Arbor], University of Michigan [Ann Arbor], University of Michigan System-University of Michigan System, Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG), Max-Planck-Gesellschaft, Université de Lille, King‘s College London, Loughborough University, National University of Singapore (NUS), University of Bristol [Bristol], University of Birmingham [Birmingham], University of Nottingham, UK (UON), University of Oxford [Oxford], The Chinese University of Hong Kong [Hong Kong], Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA), University of Oxford, Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), ALPY, Fabien
المصدر: Molecular Metabolism
Molecular metabolism
Molecular metabolism, Elsevier, 2020, 40, pp.101015. ⟨10.1016/j.molmet.2020.101015⟩
bioRxiv
Molecular metabolism, 2020, 40, pp.101015. ⟨10.1016/j.molmet.2020.101015⟩
Molecular Metabolism, Vol 40, Iss, Pp 101015-(2020)
Carrat, G, Haythorne, E, Tomas, A, Haataja, L, Muller, A, Arvan, P, Piunti, A, Cheng, K, Huang, M, Pullen, T J, Georgiadou, E, Stylianides, T, Amirruddin, N S, Salem, V, Distaso, W, Cakebread, A, Heesom, K J, Lewis, P A, Hodson, D J, Briant, L J B, Fung, A, Sessions, R B, Alpy, F, Kong, A, Benke, P, Torta, F, Keong Teo, A K, Leclerc, I, Solimena, M, Wigley, DB & Rutter, G A 2020, ' The type 2 diabetes gene product STARD10 is a phosphoinositide binding protein that controls insulin secretory granule biogenesis ', Molecular metabolism, vol. 40, 101015 . https://doi.org/10.1016/j.molmet.2020.101015مصطلحات موضوعية: Male, Proteomics, 0301 basic medicine, medicine.medical_treatment, Phosphoinositides, Phosphatidylinositols, 0601 Biochemistry and Cell Biology, Mice, chemistry.chemical_compound, Insulin granule biogenesis, Lipid transporter, Pancreatic β-cell, Type 2 diabetes, 0302 clinical medicine, Risk Factors, Insulin-Secreting Cells, Insulin Secretion, Insulin, Inositol, STARD10, Proinsulin, Mice, Knockout, [SDV.MHEP.EM] Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism, 0303 health sciences, Chemistry, Kinase, [SDV.MHEP.EM]Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism, Lipids, Cell biology, Molecular Docking Simulation, Female, Protein Binding, Insulin processing, lcsh:Internal medicine, 030209 endocrinology & metabolism, Article, Gene product, 03 medical and health sciences, medicine, Animals, Phosphatidylinositol, lcsh:RC31-1245, Molecular Biology, Alleles, 030304 developmental biology, Dense core granule, Secretory Vesicles, Cell Biology, Lipid Metabolism, Phosphoproteins, 0606 Physiology, Mice, Inbred C57BL, Disease Models, Animal, 030104 developmental biology, Diabetes Mellitus, Type 2, Carrier Proteins
وصف الملف: application/pdf
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المؤلفون: Haoning Howard Cen, Robert B Huizinga, Jelena Kolic, James D. Johnson, Leanne Beet, Evgeniy Panzhinskiy, Daren R Ure, Peter Overby, Jennifer L Cross
المصدر: Endocrinology
مصطلحات موضوعية: insulin secretion, medicine.medical_specialty, immunosuppressant, Cell Survival, medicine.medical_treatment, Context (language use), Tacrolimus, Exocytosis, Islets of Langerhans, chemistry.chemical_compound, Endocrinology, PCK1, Insulin-Secreting Cells, Diabetes mellitus, Internal medicine, medicine, Humans, Insulin, Phosphorylation, Research Articles, Cells, Cultured, geography, geography.geographical_feature_category, diabetes, NFATC Transcription Factors, business.industry, organ transplantation, medicine.disease, Islet, Phosphoric Monoester Hydrolases, Voclosporin, Calcineurin, Glucose, chemistry, Cyclosporine, business, AcademicSubjects/MED00250
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5928f288c579be8ec781b6379db45f87
https://doi.org/10.1101/2020.04.30.071324 -
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المؤلفون: Li Shao, Chunling Zhang, Xueying Liu, Libin Zhou, Yiru Wang, Yumei Zhang, Mingzhu Li
المصدر: Life sciences. 257
مصطلحات موضوعية: 0301 basic medicine, Male, medicine.medical_specialty, Pyridines, Histone Deacetylase 1, 030226 pharmacology & pharmacy, General Biochemistry, Genetics and Molecular Biology, Histone Deacetylases, Rats, Sprague-Dawley, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Internal medicine, Insulin-Secreting Cells, Insulin Secretion, medicine, Cyclic AMP, Animals, General Pharmacology, Toxicology and Pharmaceutics, Gene knockdown, geography, geography.geographical_feature_category, biology, Sodium butyrate, General Medicine, HDAC3, Islet, HDAC1, Rats, Histone Deacetylase Inhibitors, 030104 developmental biology, Endocrinology, Glucose, chemistry, Diabetes Mellitus, Type 2, Gene Knockdown Techniques, Benzamides, biology.protein, GLUT2, Calcium, Histone deacetylase, Signal transduction, Signal Transduction
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المؤلفون: Anna Drzazga, Anna Gliszczyńska, Marta Okulus, Łukasz Biegała, Edyta Gendaszewska-Darmach, Magdalena Rychlicka
المصدر: Nutrients, Vol 12, Iss 1173, p 1173 (2020)
Nutrients
Volume 12
Issue 4مصطلحات موضوعية: 0301 basic medicine, insulin secretion, Carboxylic Acids, 030209 endocrinology & metabolism, lcsh:TX341-641, Article, Calcium in biology, Receptors, G-Protein-Coupled, lysophosphatidylcholine, Mice, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Insulin-Secreting Cells, Free fatty acid receptor 1, Phosphatidylcholine, Animals, Cells, Cultured, G protein-coupled receptor, Nutrition and Dietetics, diabetes, Lysophosphatidylcholines, Benzoic Acid, Stimulation, Chemical, Glucose, 030104 developmental biology, Lysophosphatidylcholine, GPR119, chemistry, Biochemistry, GPR55, Phosphatidylcholines, GPCR (G Protein Coupled Receptors), Calcium, lipids (amino acids, peptides, and proteins), phenolic acids, lcsh:Nutrition. Foods and food supply, Food Science, Anisic acid
وصف الملف: application/pdf
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المؤلفون: Daniel Norman, Carl Johan Drott, Daniel Espes
المصدر: Peptides. 135
مصطلحات موضوعية: Blood Glucose, Chromium, Male, Fysiologi, Physiology, Biochemistry, Rats, Sprague-Dawley, chemistry.chemical_compound, Pancreatic blood flow, 0302 clinical medicine, Endocrinology, vascular, immune system diseases, Insulin-Secreting Cells, Insulin Secretion, CART, blood flow, Insulin, Amino Acids, Neurotransmitter, media_common, geography.geographical_feature_category, virus diseases, Islet, Receptor, Endothelin A, medicine.anatomical_structure, Carbohydrate Metabolism, Cart, medicine.medical_specialty, Endothelin A Receptor Antagonists, media_common.quotation_subject, 030209 endocrinology & metabolism, Nerve Tissue Proteins, Peptides, Cyclic, 03 medical and health sciences, Cellular and Molecular Neuroscience, Islets of Langerhans, Internal medicine, parasitic diseases, mental disorders, medicine, Animals, Humans, Pancreas, Anesthetics, geography, pancreatic islets, business.industry, Addiction, Pancreatic islets, Nicotinic Acids, Blood flow, Glucose Tolerance Test, Rats, Glucose, nervous system, chemistry, Regional Blood Flow, business, 030217 neurology & neurosurgery, Hormone
وصف الملف: application/pdf