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المؤلفون: Xiaodong Zhu, Mingyang Yuan, Kung-Hsien Ho, Ruiying Hu, Guoqiang Gu, Irina Kaverina
المصدر: PLoS ONE
PLoS ONE, Vol 16, Iss 7, p e0241939 (2021)مصطلحات موضوعية: 0301 basic medicine, Physiology, GTP-Binding Protein alpha Subunits, medicine.medical_treatment, Cell, GTP-Binding Protein alpha Subunits, Gi-Go, Biochemistry, Microtubules, chemistry.chemical_compound, Mice, 0302 clinical medicine, Endocrinology, Insulin-Secreting Cells, Insulin Secretion, Medicine and Health Sciences, Insulin, Electron Microscopy, Cells, Cultured, Cellular Senescence, Mice, Knockout, Microscopy, Mice, Inbred ICR, Multidisciplinary, geography.geographical_feature_category, Chemistry, Organic Compounds, Nocodazole, Monosaccharides, Islet, Cell biology, medicine.anatomical_structure, Physical Sciences, Medicine, Cellular Structures and Organelles, Research Article, Signal Transduction, Science, Carbohydrates, 030209 endocrinology & metabolism, Biosynthesis, Research and Analysis Methods, 03 medical and health sciences, stomatognathic system, Microtubule, medicine, Animals, Secretion, Vesicles, Diabetic Endocrinology, geography, Endocrine Physiology, Secretory Vesicles, Organic Chemistry, Cell Membrane, Chemical Compounds, Biology and Life Sciences, Biological Transport, Cell Biology, Hormones, 030104 developmental biology, Glucose, Metabolism, Transmission Electron Microscopy, Physiological Processes, Function (biology)
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المصدر: Evidence-based Complementary and Alternative Medicine : eCAM
Evidence-Based Complementary and Alternative Medicine, Vol 2021 (2021)مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Article Subject, Cinnamaldehyde, Nitric oxide, Other systems of medicine, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Insulin resistance, Internal medicine, medicine, Insulin secretion, geography, geography.geographical_feature_category, biology, digestive, oral, and skin physiology, nutritional and metabolic diseases, food and beverages, High fat diet, medicine.disease, Islet, Obesity, Nitric oxide synthase, 030104 developmental biology, Endocrinology, Complementary and alternative medicine, chemistry, 030220 oncology & carcinogenesis, biology.protein, RZ201-999, Research Article
وصف الملف: text/xhtml
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المؤلفون: Siming Liu, Kristen E. Rohli, Jonathan V. Rocheleau, Yumi Imai, Vidhant Pal, Eric B. Taylor, Samuel B. Stephens, Cierra K. Boyer, Casey J. Bauchle
المصدر: Diabetes
مصطلحات موضوعية: medicine.medical_specialty, Isocitrates, IDH1, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Citric Acid, chemistry.chemical_compound, Mice, Cytosol, Internal medicine, Insulin-Secreting Cells, Insulin Secretion, Internal Medicine, medicine, Glucose homeostasis, Animals, Homeostasis, Mice, Knockout, geography, geography.geographical_feature_category, Chemistry, Insulin, Glutathione, Islet, Mitochondria, Endocrinology, Isocitrate dehydrogenase, Glucose, Islet Studies
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f48405d6238ce5eed87cc25ce6da3af
https://europepmc.org/articles/PMC8385611/ -
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المؤلفون: Marilyne Vandel, Christine A. Doucette, Mario Fonseca, Genevieve C. Sparagna, Grant M. Hatch, Nivedita Seshadri, Bo Xiang, Prasoon Agarwal, Vernon W. Dolinsky, Laura K. Cole
المصدر: Endocrinology
مصطلحات موضوعية: Male, medicine.medical_specialty, Cardiolipins, medicine.medical_treatment, Tafazzin, Mice, Transgenic, Islets of Langerhans, Mice, 03 medical and health sciences, chemistry.chemical_compound, Oxygen Consumption, 0302 clinical medicine, Endocrinology, Internal medicine, Insulin Secretion, medicine, Cardiolipin, Animals, Pancreatic islet function, Inner mitochondrial membrane, Pancreas, Research Articles, 030304 developmental biology, 0303 health sciences, geography, geography.geographical_feature_category, biology, Insulin, Pancreatic islets, Islet, Fibrosis, Mitochondria, Mice, Inbred C57BL, medicine.anatomical_structure, chemistry, Doxycycline, Gene Knockdown Techniques, Fatty Acids, Unsaturated, biology.protein, Female, Oxidation-Reduction, Acyltransferases, 030217 neurology & neurosurgery
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b5a91ca16907c450487be09287e9d17
https://doi.org/10.1210/endocr/bqab102 -
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المؤلفون: Vanessa L.S. LaPointe, Rick de Vries, Sami G. Mohammed, Marten A. Engelse, Mireille M.J.P.E. Sthijns, Adam Stell, Aart A. van Apeldoorn, Eelco J.P. de Koning
المصدر: Journal of Immunology and Regenerative Medicine. 16:100055
مصطلحات موضوعية: endocrine system, Scaffold, geography, geography.geographical_feature_category, endocrine system diseases, Chemistry, Polyphenylsulfone, Pharmacology, Islet, Synthetic polymer, In vitro, Transplantation, chemistry.chemical_compound, Beta cell, Insulin secretion
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المؤلفون: Nancy Antoine, Lucie Ruiz, Holger Klein, Patrick Gilon, Anne Wojtusciszyn, Fiona M. Gribble, Frank Reimann, Robert Augustin, Bao-Khanh Lai, Bilal Singh, Michael P. Pieper, Eva Gatineau, Nano Rita, Mohammed Bensellam, Pedro Luis Herrera, Birgit Stierstorfer, Firas Khattab, Heeyoung Chae, Lorenzo Piemonti, Davide Brusa, Michael Mark, Eric Mayoux, Christophe Broca
المساهمون: Université Catholique de Louvain = Catholic University of Louvain (UCL), Boehringer Ingelheim Pharma GmbH & Co. KG, University of Geneva [Switzerland], Addenbrooke's Hospital, Cambridge University NHS Trust, Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Lausanne University Hospital, IRCCS Ospedale San Raffaele [Milan, Italy], Chae, Heeyoung, Augustin, Robert, Gatineau, Eva, Mayoux, Eric, Bensellam, Mohammed, Antoine, Nancy, Khattab, Fira, Lai, Bao-Khanh, Brusa, Davide, Stierstorfer, Birgit, Klein, Holger, Singh, Bilal, Ruiz, Lucie, Pieper, Michael, Mark, Michael, Herrera, Pedro L, Gribble, Fiona M, Reimann, Frank, Wojtusciszyn, Anne, Broca, Christophe, Rita, Nano, Piemonti, Lorenzo, Gilon, Patrick, Gribble, Fiona [0000-0002-4232-2898], Reimann, Frank [0000-0001-9399-6377], Apollo - University of Cambridge Repository
المصدر: Molecular Metabolism
Molecular metabolism, vol. 42, pp. 101071
Molecular metabolism
Molecular metabolism, Elsevier, 2020, 42, pp.101071. ⟨10.1016/j.molmet.2020.101071⟩
Molecular Metabolism (2020) P. 101071
Molecular Metabolism, Vol 42, Iss, Pp 101071-(2020)مصطلحات موضوعية: 0301 basic medicine, Blood Glucose, medicine.medical_treatment, IC50, half maximal inhibitory concentration, SGLT2i, sodium-glucose cotransporter 2 inhibitors, MESH: Insulin Secretion, MESH: Glucosides, MESH: Insulin-Secreting Cells, chemistry.chemical_compound, Mice, αMG, α-methyl-D-glucopyranoside, EGP, endogenous glucose production, 0302 clinical medicine, Glucosides, Glucagon-Like Peptide 1, Insulin-Secreting Cells, FACS, fluorescence-activated cell sorting, Insulin Secretion, Insulin, ddc:576.5, MESH: Animals, Dapagliflozin, geography.geographical_feature_category, Chemistry, MESH: Glucagon, BW, body weight, Diabetes, SGLT2 inhibitor, MESH: Pancreas, [SDV.MHEP.EM]Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism, Islet, 3. Good health, SGLT, sodium-glucose cotransporter, MESH: Glucose, MESH: Sodium-Glucose Transporter 2, No direct effect of SGLT2i on α- and β-cells, MESH: Sodium-Glucose Transporter 2 Inhibitors, Ketone bodies, Original Article, medicine.medical_specialty, lcsh:Internal medicine, endocrine system, MESH: Rats, 030209 endocrinology & metabolism, MESH: Insulin, Glucagon, 03 medical and health sciences, Islets of Langerhans, Gliflozins, TPM, transcripts per million, Sodium-Glucose Transporter 2, G, glucose, In vivo, Internal medicine, Empagliflozin, medicine, MESH: Benzhydryl Compounds, Animals, Humans, Benzhydryl Compounds, lcsh:RC31-1245, Molecular Biology, MESH: Mice, Pancreas, Sodium-Glucose Transporter 2 Inhibitors, geography, MESH: Humans, MESH: Islets of Langerhans, Glucose transporter, MESH: Glucagon-Like Peptide 1, Cell Biology, Rats, 030104 developmental biology, Endocrinology, Glucose, Glucagon-Secreting Cells, MESH: Blood Glucose, MESH: Glucagon-Secreting Cells, Cmax, maximum serum concentration, diabetes, glucagon, insulin
وصف الملف: application/pdf
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المؤلفون: Takayuki Anazawa, Takeshi Hori, Osamu Kurosawa, Hiroo Iwata, Kei Yamane
المصدر: Biomedical Microdevices. 21
مصطلحات موضوعية: endocrine system, Materials science, Biomedical Engineering, 02 engineering and technology, 01 natural sciences, Islets of Langerhans, Mice, chemistry.chemical_compound, Lab-On-A-Chip Devices, Insulin Secretion, medicine, Animals, Fluidics, Dimethylpolysiloxanes, Insulin secretion, Molecular Biology, geography, geography.geographical_feature_category, Polydimethylsiloxane, Pancreatic islets, 010401 analytical chemistry, Equipment Design, 021001 nanoscience & nanotechnology, Chip, Hydraulic pressure, Islet, 0104 chemical sciences, Transplantation, Nylons, Glucose, medicine.anatomical_structure, chemistry, 0210 nano-technology, Biomedical engineering
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المصدر: Endocrinology, Diabetes & Metabolism, Vol 4, Iss 2, Pp n/a-n/a (2021)
Endocrinology, Diabetes & Metabolismمصطلحات موضوعية: Male, medicine.medical_specialty, Cell type, Imeglimin, Endocrinology, Diabetes and Metabolism, Apoptosis, Type 2 diabetes, lcsh:Diseases of the endocrine glands. Clinical endocrinology, chemistry.chemical_compound, In vivo, Original Research Articles, Insulin-Secreting Cells, Internal medicine, Glucose Intolerance, Insulin Secretion, medicine, Animals, Insulin, Original Research Article, new therapies, Cells, Cultured, Cell Proliferation, geography, geography.geographical_feature_category, lcsh:RC648-665, islet, Triazines, business.industry, imeglimin, medicine.disease, Islet, animal models, Rats, Zucker, Disease Models, Animal, Endocrinology, medicine.anatomical_structure, Diabetes Mellitus, Type 2, Basal (medicine), chemistry, Hyperglycemia, business, Pancreas
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المؤلفون: Kelly Meneyrol, Christophe Magnan, Ánxela Estévez-Salguero, Jeanne Guitton, Miguel López, Hervé Le Stunff, Ismael González-García, Yacir Benomar, Mohammed Taouis
المساهمون: Unité de Biologie Fonctionnelle et Adaptative (BFA (UMR_8251 / U1133)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), NeurObesity Group, Department of Physiology, University of Santiago de Compostela (CIMUS), Institut des Neurosciences Paris-Saclay (NeuroPSI), Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)
المصدر: Metabolism
Metabolism, Elsevier, 2021, 123, pp.154846. ⟨10.1016/j.metabol.2021.154846⟩مصطلحات موضوعية: Blood Glucose, Endocrinology, Diabetes and Metabolism, [SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology, Serine C-Palmitoyltransferase, Stimulation, Type 2 diabetes, Primary Ovarian Insufficiency, Weight Gain, Rats, Sprague-Dawley, chemistry.chemical_compound, 0302 clinical medicine, Endocrinology, Insulin Secretion, Glucose homeostasis, Homeostasis, Ovariectomy: oestrogens, 2. Zero hunger, Neurons, 0303 health sciences, geography.geographical_feature_category, [SDV.NEU.PC]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Psychology and behavior, Estradiol, Chemistry, [SDV.NEU.SC]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Cognitive Sciences, Islet, Ventromedial nucleus of the hypothalamus, Hypothalamus, Ovariectomized rat, Female, Hypothalamus: ceramide, Microglia, hormones, hormone substitutes, and hormone antagonists, Ceramide, medicine.medical_specialty, endocrine system, Ovariectomy, Down-Regulation, 030209 endocrinology & metabolism, Ceramides, 03 medical and health sciences, Internal medicine, medicine, Animals, Obesity, Gene Silencing, 030304 developmental biology, geography, medicine.disease, Rats
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المؤلفون: Jeffrey S. Isenberg, Keiko Omori, Meirigeng Qi, Youjun Wu, Luis Valiente, Ismail H. Al-Abdullah, Bashar Khiatah, Jiing-Kuan Yee, Rachel Perez, Kuan-Tsen Chen, Fouad Kandeel
المصدر: Scientific Reports, Vol 9, Iss 1, Pp 1-6 (2019)
Scientific Reportsمصطلحات موضوعية: 0301 basic medicine, Embryonic stem cells, Zinc binding, medicine.medical_treatment, Science, Cell, Cell Culture Techniques, chemistry.chemical_element, Cell Separation, Zinc, Article, Islets of Langerhans, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Insulin Secretion, medicine, Humans, Insulin, geography, Multidisciplinary, geography.geographical_feature_category, Temperature, Reproducibility of Results, Cell Differentiation, Islet, Embryonic stem cell, In vitro, Stem-cell research, Cell biology, 030104 developmental biology, medicine.anatomical_structure, Microscopy, Fluorescence, chemistry, Dithizone, Medicine, 030217 neurology & neurosurgery