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المصدر: Current Biology. 12:435-438
مصطلحات موضوعية: Immunoglobulin gene, Molecular Sequence Data, Gene Conversion, Immunoglobulin Variable Region, Somatic hypermutation, Biology, General Biochemistry, Genetics and Molecular Biology, Cell Line, Affinity maturation, Mice, Cytidine Deaminase, medicine, Animals, Humans, Amino Acid Sequence, Gene conversion, Gene, B cell, B-Lymphocytes, Sequence Homology, Amino Acid, Agricultural and Biological Sciences(all), Biochemistry, Genetics and Molecular Biology(all), Gene targeting, Gene rearrangement, Molecular biology, medicine.anatomical_structure, Gene Targeting, Rabbits, General Agricultural and Biological Sciences, Chickens
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المؤلفون: David G. Schatz, Jessica J. McDonald, Jean-Marie Buerstedde, Jukka Alinikula, Hiroshi Arakawa
المصدر: PLoS Biology
PLoS Biology, Vol 12, Iss 4, p e1001831 (2014)مصطلحات موضوعية: B Cells, Transcription, Genetic, Lymphocyte Activation, Biochemistry, E-Box Elements, White Blood Cells, Gene Knockout Techniques, Mice, 0302 clinical medicine, Animal Cells, Nucleic Acids, Molecular Cell Biology, Biology (General), Immune Response, 0303 health sciences, B-Lymphocytes, Immune System Proteins, MEF2 Transcription Factors, General Neuroscience, NF-kappa B, Cytidine deaminase, 3. Good health, Enhancer Elements, Genetic, Cellular Types, General Agricultural and Biological Sciences, DNA modification, Research Article, QH301-705.5, Immune Cells, DNA transcription, Immunology, Green Fluorescent Proteins, Somatic hypermutation, Biology, General Biochemistry, Genetics and Molecular Biology, Antibodies, Cell Line, Affinity maturation, 03 medical and health sciences, Immunoglobulin kappa-Chains, Immunoglobulin lambda-Chains, Cytidine Deaminase, Genetics, Animals, Humans, Enhancer, Uracil-DNA Glycosidase, Gene, Transcription factor, 030304 developmental biology, Blood Cells, Binding Sites, General Immunology and Microbiology, Biology and life sciences, Point mutation, Proteins, DNA, Cell Biology, Molecular biology, Mutation, Gene expression, Somatic Hypermutation, Immunoglobulin, Chickens, Sequence Alignment, 030215 immunology
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المؤلفون: Jamie L. Duke, David G. Schatz, Steven H. Kleinstein, Sally Tan, Hiroshi Arakawa, Kristin M. Kohler, Jean-Marie Buerstedde, Jessica J. McDonald
المصدر: Journal of immunology (Baltimore, Md. : 1950). 189(11)
مصطلحات موضوعية: Chromatin Immunoprecipitation, Transcription, Genetic, DNA damage, Immunology, Immunoglobulin Variable Region, Somatic hypermutation, RNA polymerase II, Biology, Article, Affinity maturation, Cytidine Deaminase, Serine, Immunology and Allergy, Animals, 3' Flanking Region, Phosphorylation, Enhancer, Gene, Cells, Cultured, Genetics, Immunoassay, B-Lymphocytes, Genes, Immunoglobulin, Cytidine deaminase, DNA, Enhancer Elements, Genetic, Genetic Loci, Mutation, biology.protein, RNA Polymerase II, Somatic Hypermutation, Immunoglobulin, Chromatin immunoprecipitation, Chickens
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0f049bc5a8ee3e29ffcfaadef56d0c2
https://pubmed.ncbi.nlm.nih.gov/23087403 -
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المؤلفون: Daisuke Kitamura, Hiroshi Arakawa, Shinsuke Araki, Ryushin Mizuta, Noriaki Okamoto, Mariko Okamoto
المصدر: Immunology letters. 125(1)
مصطلحات موضوعية: Immunology, Immunoglobulin Variable Region, Somatic hypermutation, Biology, Gene mutation, Cell Line, Affinity maturation, chemistry.chemical_compound, Immunology and Allergy, Animals, DNA Breaks, Double-Stranded, Gene, B-Lymphocytes, Endodeoxyribonucleases, Genes, Immunoglobulin, Point mutation, Cytidine deaminase, DNA, Molecular biology, chemistry, Mutation, biology.protein, Somatic Hypermutation, Immunoglobulin, Antibody, Chickens