المؤلفون: Yang L; College of Veterinary Medicine, China Agricultural University, Beijing 100094, China., Yuan Y; College of Veterinary Medicine, China Agricultural University, Beijing 100094, China; Key Biology Laboratory of Chinese Veterinary Medicine, Ministry of Agriculture and Rural Affairs, Beijing 100094, China; National Center of Technology Innovation for Medicinal Function of Food, National Food and Strategic Reserves Administration, Beijing 100193, China; Qingdao Animal Husbandry Workstation, Oingdao, Shandong 266100, China., Xiong L; College of Veterinary Medicine, China Agricultural University, Beijing 100094, China., Zhao Q; College of Veterinary Medicine, China Agricultural University, Beijing 100094, China; Key Biology Laboratory of Chinese Veterinary Medicine, Ministry of Agriculture and Rural Affairs, Beijing 100094, China; National Center of Technology Innovation for Medicinal Function of Food, National Food and Strategic Reserves Administration, Beijing 100193, China; Qingdao Animal Husbandry Workstation, Oingdao, Shandong 266100, China., Yang M; Key Biology Laboratory of Chinese Veterinary Medicine, Ministry of Agriculture and Rural Affairs, Beijing 100094, China; National Center of Technology Innovation for Medicinal Function of Food, National Food and Strategic Reserves Administration, Beijing 100193, China; Qingdao Animal Husbandry Workstation, Oingdao, Shandong 266100, China., Suo X; College of Veterinary Medicine, China Agricultural University, Beijing 100094, China., Hao Z; College of Veterinary Medicine, China Agricultural University, Beijing 100094, China; Key Biology Laboratory of Chinese Veterinary Medicine, Ministry of Agriculture and Rural Affairs, Beijing 100094, China; National Center of Technology Innovation for Medicinal Function of Food, National Food and Strategic Reserves Administration, Beijing 100193, China; Qingdao Animal Husbandry Workstation, Oingdao, Shandong 266100, China.

المصدر: Veterinary parasitology [Vet Parasitol] 2024 Jul; Vol. 329, pp. 110194. Date of Electronic Publication: 2024 May 03.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7602745 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2550 (Electronic) Linking ISSN: 03044017 NLM ISO Abbreviation: Vet Parasitol Subsets: MEDLINE

مواضيع طبية MeSH: Eimeria tenella*/drug effects , Chickens* , Apoptosis*/drug effects , Cecum*/parasitology , Coccidiosis*/veterinary , Coccidiosis*/drug therapy , Coccidiosis*/parasitology , Poultry Diseases*/parasitology , Poultry Diseases*/drug therapy, Animals ; Coccidiostats/pharmacology ; Coccidiostats/therapeutic use

المؤلفون: Yu H; College of Animal Science and Technology, Yangzhou University, Yangzhou, China., Tang J; College of Animal Science and Technology, Yangzhou University, Yangzhou, China., Dong L; College of Animal Science and Technology, Yangzhou University, Yangzhou, China., Tang M; College of Animal Science and Technology, Yangzhou University, Yangzhou, China., Arif A; College of Animal Science and Technology, Yangzhou University, Yangzhou, China., Zhang T; College of Animal Science and Technology, Yangzhou University, Yangzhou, China., Zhang G; College of Animal Science and Technology, Yangzhou University, Yangzhou, China., Xie K; College of Animal Science and Technology, Yangzhou University, Yangzhou, China., Zhao Z; Poultry Institute, Chinese Academy of Agricultural Sciences, Yangzhou, China., Dai G; College of Animal Science and Technology, Yangzhou University, Yangzhou, China. Electronic address: Daigj@yzu.edu.cn.

المصدر: International journal of biological macromolecules [Int J Biol Macromol] 2024 Jun; Vol. 269 (Pt 1), pp. 131807. Date of Electronic Publication: 2024 Apr 25.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE

مواضيع طبية MeSH: Chickens* , Coccidiosis*/veterinary , Coccidiosis*/immunology , Coccidiosis*/genetics , Coccidiosis*/parasitology , Eimeria tenella* , Gene Expression Profiling* , MicroRNAs*/genetics , Poultry Diseases*/parasitology , Poultry Diseases*/genetics , Poultry Diseases*/immunology, Animals ; Cecum/parasitology ; Cell Line ; Cytokines/metabolism ; Cytokines/genetics ; Gene Expression Regulation ; Inflammation/genetics ; Inflammation/immunology ; Inflammation/parasitology ; Signal Transduction ; Transcriptome ; Male ; Female

المؤلفون: Chen W; College of Veterinary Medicine, Northeast Agricultural University, NO. 600 Changjiang Road, Xiangfang District, Harbin, Heilongjiang, 150030, China.; Heilongjiang Key Laboratory for Experimental Animals and Comparative Medicine, Harbin, Heilongjiang, 150030, China., Ma C; College of Food Science, Northeast Agricultural University, Harbin, Heilongjiang, 150030, China., Li G; College of Veterinary Medicine, Northeast Agricultural University, NO. 600 Changjiang Road, Xiangfang District, Harbin, Heilongjiang, 150030, China., Jia Z; College of Veterinary Medicine, Northeast Agricultural University, NO. 600 Changjiang Road, Xiangfang District, Harbin, Heilongjiang, 150030, China., Yang X; College of Veterinary Medicine, Northeast Agricultural University, NO. 600 Changjiang Road, Xiangfang District, Harbin, Heilongjiang, 150030, China., Pan X; College of Veterinary Medicine, Northeast Agricultural University, NO. 600 Changjiang Road, Xiangfang District, Harbin, Heilongjiang, 150030, China., Ma D; College of Veterinary Medicine, Northeast Agricultural University, NO. 600 Changjiang Road, Xiangfang District, Harbin, Heilongjiang, 150030, China. madexing@neau.edu.cn.; Heilongjiang Key Laboratory for Experimental Animals and Comparative Medicine, Harbin, Heilongjiang, 150030, China. madexing@neau.edu.cn.

المصدر: Veterinary research [Vet Res] 2021 Feb 17; Vol. 52 (1), pp. 24. Date of Electronic Publication: 2021 Feb 17.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 9309551 Publication Model: Electronic Cited Medium: Internet ISSN: 1297-9716 (Electronic) Linking ISSN: 09284249 NLM ISO Abbreviation: Vet Res Subsets: MEDLINE

مواضيع طبية MeSH: Chickens*, Coccidiosis/*veterinary , Eimeria tenella/*immunology , Poultry Diseases/*prevention & control , Protozoan Proteins/*immunology , Sporozoites/*immunology, Animals ; Bacteriophages ; Cecum/pathology ; Coccidiosis/prevention & control ; Molecular Docking Simulation ; Poultry Diseases/parasitology ; Protein Binding ; Protein Conformation

المؤلفون: Huang H; College of Animal Science and Technology, Jilin Provincial Engineering Research Center of Animal Probiotics, Key Laboratory of Animal Production and Product Quality Safety of Ministry of Education, Jilin Agricultural University, Changchun, China., Jiang Y; College of Animal Science and Technology, Jilin Provincial Engineering Research Center of Animal Probiotics, Key Laboratory of Animal Production and Product Quality Safety of Ministry of Education, Jilin Agricultural University, Changchun, China., Zhou F; College of Animal Science and Technology, Jilin Provincial Engineering Research Center of Animal Probiotics, Key Laboratory of Animal Production and Product Quality Safety of Ministry of Education, Jilin Agricultural University, Changchun, China., Shi C; College of Animal Science and Technology, Jilin Provincial Engineering Research Center of Animal Probiotics, Key Laboratory of Animal Production and Product Quality Safety of Ministry of Education, Jilin Agricultural University, Changchun, China., Yang W; College of Animal Science and Technology, Jilin Provincial Engineering Research Center of Animal Probiotics, Key Laboratory of Animal Production and Product Quality Safety of Ministry of Education, Jilin Agricultural University, Changchun, China., Wang J; College of Animal Science and Technology, Jilin Provincial Engineering Research Center of Animal Probiotics, Key Laboratory of Animal Production and Product Quality Safety of Ministry of Education, Jilin Agricultural University, Changchun, China., Kang Y; College of Animal Science and Technology, Jilin Provincial Engineering Research Center of Animal Probiotics, Key Laboratory of Animal Production and Product Quality Safety of Ministry of Education, Jilin Agricultural University, Changchun, China., Cao X; College of Animal Science and Technology, Jilin Provincial Engineering Research Center of Animal Probiotics, Key Laboratory of Animal Production and Product Quality Safety of Ministry of Education, Jilin Agricultural University, Changchun, China., Wang C; College of Animal Science and Technology, Jilin Provincial Engineering Research Center of Animal Probiotics, Key Laboratory of Animal Production and Product Quality Safety of Ministry of Education, Jilin Agricultural University, Changchun, China. Electronic address: wangchunfeng@jlau.edu.cn., Yang G; College of Animal Science and Technology, Jilin Provincial Engineering Research Center of Animal Probiotics, Key Laboratory of Animal Production and Product Quality Safety of Ministry of Education, Jilin Agricultural University, Changchun, China. Electronic address: yangguilian@jlau.edu.cn.

المصدر: Experimental parasitology [Exp Parasitol] 2020 Aug; Vol. 215, pp. 107901. Date of Electronic Publication: 2020 Jun 07.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Academic Press Country of Publication: United States NLM ID: 0370713 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2449 (Electronic) Linking ISSN: 00144894 NLM ISO Abbreviation: Exp Parasitol Subsets: MEDLINE

مواضيع طبية MeSH: Protozoan Vaccines*, 12E7 Antigen/*immunology , Chickens/*parasitology , Coccidiosis/*veterinary , Eimeria tenella/*immunology , Poultry Diseases/*prevention & control, Animals ; Antigens, Protozoan/immunology ; Cecum/parasitology ; Coccidiosis/economics ; Coccidiosis/parasitology ; Coccidiosis/prevention & control ; Eimeria tenella/chemistry ; Flow Cytometry/veterinary ; Fluorescent Antibody Technique, Indirect/veterinary ; Immunoglobulin A, Secretory/biosynthesis ; Immunoglobulin G/blood ; Interferon-gamma/blood ; Interleukin-2/blood ; Intestines/immunology ; Lactobacillus plantarum/genetics ; Lactobacillus plantarum/immunology ; Poultry Diseases/economics ; Poultry Diseases/parasitology ; Random Allocation ; Vaccines, Synthetic

المؤلفون: Chen HL; College of Animal Science and Technology, Jilin Provincial Engineering Research Center of Animal Probiotics, Key Laboratory of Animal Production and Product Quality Safety of Ministry of Education, Jilin Agricultural University, Changchun, China., Zhao XY; College of Animal Science and Technology, Jilin Provincial Engineering Research Center of Animal Probiotics, Key Laboratory of Animal Production and Product Quality Safety of Ministry of Education, Jilin Agricultural University, Changchun, China., Zhao GX; College of Animal Science and Technology, Jilin Provincial Engineering Research Center of Animal Probiotics, Key Laboratory of Animal Production and Product Quality Safety of Ministry of Education, Jilin Agricultural University, Changchun, China., Huang HB; College of Animal Science and Technology, Jilin Provincial Engineering Research Center of Animal Probiotics, Key Laboratory of Animal Production and Product Quality Safety of Ministry of Education, Jilin Agricultural University, Changchun, China., Li HR; College of Animal Science and Technology, Jilin Provincial Engineering Research Center of Animal Probiotics, Key Laboratory of Animal Production and Product Quality Safety of Ministry of Education, Jilin Agricultural University, Changchun, China., Shi CW; College of Animal Science and Technology, Jilin Provincial Engineering Research Center of Animal Probiotics, Key Laboratory of Animal Production and Product Quality Safety of Ministry of Education, Jilin Agricultural University, Changchun, China., Yang WT; College of Animal Science and Technology, Jilin Provincial Engineering Research Center of Animal Probiotics, Key Laboratory of Animal Production and Product Quality Safety of Ministry of Education, Jilin Agricultural University, Changchun, China., Jiang YL; College of Animal Science and Technology, Jilin Provincial Engineering Research Center of Animal Probiotics, Key Laboratory of Animal Production and Product Quality Safety of Ministry of Education, Jilin Agricultural University, Changchun, China., Wang JZ; College of Animal Science and Technology, Jilin Provincial Engineering Research Center of Animal Probiotics, Key Laboratory of Animal Production and Product Quality Safety of Ministry of Education, Jilin Agricultural University, Changchun, China., Ye LP; College of Animal Science and Technology, Jilin Provincial Engineering Research Center of Animal Probiotics, Key Laboratory of Animal Production and Product Quality Safety of Ministry of Education, Jilin Agricultural University, Changchun, China., Zhao Q; College of Animal Science and Technology, Jilin Provincial Engineering Research Center of Animal Probiotics, Key Laboratory of Animal Production and Product Quality Safety of Ministry of Education, Jilin Agricultural University, Changchun, China., Wang CF; College of Animal Science and Technology, Jilin Provincial Engineering Research Center of Animal Probiotics, Key Laboratory of Animal Production and Product Quality Safety of Ministry of Education, Jilin Agricultural University, Changchun, China. wangchunfeng@jlau.edu.cn., Yang GL; College of Animal Science and Technology, Jilin Provincial Engineering Research Center of Animal Probiotics, Key Laboratory of Animal Production and Product Quality Safety of Ministry of Education, Jilin Agricultural University, Changchun, China. yangguilian@jlau.edu.cn.

المصدر: Parasites & vectors [Parasit Vectors] 2020 Feb 11; Vol. 13 (1), pp. 56. Date of Electronic Publication: 2020 Feb 11.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101462774 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-3305 (Electronic) Linking ISSN: 17563305 NLM ISO Abbreviation: Parasit Vectors Subsets: MEDLINE

مواضيع طبية MeSH: Chickens*/microbiology , Chickens*/parasitology , Eimeria tenella*/genetics , Eimeria tenella*/parasitology, Coccidiosis/*veterinary , Gastrointestinal Microbiome/*genetics , Poultry Diseases/*parasitology, Animals ; Bacteria/classification ; Bacteria/isolation & purification ; Cecum/microbiology ; Cecum/parasitology ; Cecum/pathology ; Coccidiosis/therapy ; Metagenomics ; RNA, Ribosomal, 16S/genetics

المؤلفون: Schneiders GH; NutriGenomics Laboratory, Department of Poultry Science, University of Georgia, Athens, Georgia 30602., Foutz JC; NutriGenomics Laboratory, Department of Poultry Science, University of Georgia, Athens, Georgia 30602., Fuller AL; NutriGenomics Laboratory, Department of Poultry Science, University of Georgia, Athens, Georgia 30602., Nelson J; Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, Georgia 30602., Rekaya R; Department of Animal and Dairy Science, University of Georgia, Athens, Georgia 30602., Aggrey SE; NutriGenomics Laboratory, Department of Poultry Science, University of Georgia, Athens, Georgia 30602.

المصدر: The Journal of parasitology [J Parasitol] 2020 Jun 01; Vol. 106 (3), pp. 428-437.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Society of Parasitologists [etc.] Country of Publication: United States NLM ID: 7803124 Publication Model: Print Cited Medium: Internet ISSN: 1937-2345 (Electronic) Linking ISSN: 00223395 NLM ISO Abbreviation: J Parasitol Subsets: MEDLINE

مواضيع طبية MeSH: Chickens/*parasitology , Coccidiosis/*veterinary , Eimeria tenella/*physiology , Heat Stress Disorders/*veterinary , Poultry Diseases/*parasitology, Animals ; Cattle ; Cecum/pathology ; Cell Line ; Coccidiosis/parasitology ; Eimeria tenella/growth & development ; Eimeria tenella/pathogenicity ; Flow Cytometry/veterinary ; Heat Stress Disorders/complications ; Hot Temperature ; Merozoites/growth & development ; Merozoites/physiology ; Sporozoites/physiology

المؤلفون: El-Shazly KA; Pharmacology Department, Faculty of Veterinary Medicine, KafrElsheikh University, Kafr El-Sheikh, Egypt., El-Latif AA; Pharmacology Department, Faculty of Veterinary Medicine, KafrElsheikh University, Kafr El-Sheikh, Egypt., Abdo W; Department of Pathology and Clinical Pathology, Faculty of Veterinary Medicine, KafrElsheikh University, Kafr El-Sheikh, Egypt., El-Morsey A; Parasitology and Animal Diseases Department, Veterinary Research Division, National Research Centre, 33 El Bohouth St. (former El-Tahrir St.), Dokki, P.O. 12622, Giza, Egypt. el.el-sayed@nrc.sci.eg., El-Aziz MIA; Pharmacology Department, Faculty of Veterinary Medicine, KafrElsheikh University, Kafr El-Sheikh, Egypt., El-Mogazy H; Poultry Production and Medicine Unit, Veterinary Administration, Kafr El-Sheikh, Kafr El-Sheikh Province, Egypt.

المصدر: Parasitology research [Parasitol Res] 2020 Jun; Vol. 119 (6), pp. 1955-1968. Date of Electronic Publication: 2020 May 13.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Springer International Country of Publication: Germany NLM ID: 8703571 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1955 (Electronic) Linking ISSN: 09320113 NLM ISO Abbreviation: Parasitol Res Subsets: MEDLINE

مواضيع طبية MeSH: Eimeria tenella*, Chickens/*parasitology , Coccidiosis/*veterinary , Coccidiostats/*pharmacology , Fluoroquinolones/*therapeutic use , Poultry Diseases/*drug therapy, Animals ; Cecum/pathology ; Coccidiosis/drug therapy ; Feces/parasitology ; Nitriles/therapeutic use ; Oocysts/drug effects ; Poultry Diseases/parasitology ; Triazines/therapeutic use ; Weight Gain/drug effects

المؤلفون: Zhou BH; College of Animal Science and Technology, Henan University of Science and Technology, Luoyang 471000, Henan, People's Republic of China. Electronic address: zhoubh@haust.edu.cn., Jia LS; College of Animal Science and Technology, Henan University of Science and Technology, Luoyang 471000, Henan, People's Republic of China., Wei SS; College of Animal Science and Technology, Henan University of Science and Technology, Luoyang 471000, Henan, People's Republic of China., Ding HY; College of Animal Science and Technology, Henan University of Science and Technology, Luoyang 471000, Henan, People's Republic of China., Yang JY; College of Animal Science and Technology, Henan University of Science and Technology, Luoyang 471000, Henan, People's Republic of China., Wang HW; College of Animal Science and Technology, Henan University of Science and Technology, Luoyang 471000, Henan, People's Republic of China. Electronic address: wanghw@haust.edu.cn.

المصدر: Poultry science [Poult Sci] 2020 Mar; Vol. 99 (3), pp. 1297-1305. Date of Electronic Publication: 2020 Jan 22.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: England NLM ID: 0401150 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-3171 (Electronic) Linking ISSN: 00325791 NLM ISO Abbreviation: Poult Sci Subsets: MEDLINE

مواضيع طبية MeSH: Chickens*, Coccidiosis/*veterinary , Eimeria tenella/*physiology , Intestinal Mucosa/*microbiology , Poultry Diseases/*parasitology, Animals ; Cecum/microbiology ; Coccidiosis/parasitology ; Gastrointestinal Microbiome/drug effects ; Male ; RNA, Ribosomal, 16S/analysis

المؤلفون: Macdonald SE; Department of Pathobiology and Population Sciences, Royal Veterinary College, University of London, Hatfield, United Kingdom., Nolan MJ; Department of Pathobiology and Population Sciences, Royal Veterinary College, University of London, Hatfield, United Kingdom., Harman K; Department of Pathobiology and Population Sciences, Royal Veterinary College, University of London, Hatfield, United Kingdom., Boulton K; The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Midlothian, United Kingdom., Hume DA; The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Midlothian, United Kingdom., Tomley FM; Department of Pathobiology and Population Sciences, Royal Veterinary College, University of London, Hatfield, United Kingdom., Stabler RA; Department of Pathogen Molecular Biology, London School of Hygiene and Tropical Medicine, London, United Kingdom., Blake DP; Department of Pathobiology and Population Sciences, Royal Veterinary College, University of London, Hatfield, United Kingdom.

المصدر: PloS one [PLoS One] 2017 Sep 21; Vol. 12 (9), pp. e0184890. Date of Electronic Publication: 2017 Sep 21 (Print Publication: 2017).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

مواضيع طبية MeSH: Eimeria tenella* , Gastrointestinal Microbiome*/genetics, Bird Diseases/*microbiology , Cecum/*microbiology , Chickens/*microbiology , Coccidiosis/*veterinary, Animals ; Bird Diseases/pathology ; Cecum/pathology ; Coccidiosis/microbiology ; Coccidiosis/pathology ; Phylogeny ; RNA, Ribosomal, 16S/genetics ; Random Allocation ; Sequence Analysis, DNA ; Severity of Illness Index

المؤلفون: Rafiqi SI; Division of Parasitology, ICAR-Indian Veterinary Research Institute, Izatnagar, Uttar Pradesh, 243122, India., Garg R; Division of Parasitology, ICAR-Indian Veterinary Research Institute, Izatnagar, Uttar Pradesh, 243122, India. rajatgarg_2000@yahoo.com., Ram H; Division of Parasitology, ICAR-Indian Veterinary Research Institute, Izatnagar, Uttar Pradesh, 243122, India., Reena KK; Division of Parasitology, ICAR-Indian Veterinary Research Institute, Izatnagar, Uttar Pradesh, 243122, India., Asari M; Division of Parasitology, ICAR-Indian Veterinary Research Institute, Izatnagar, Uttar Pradesh, 243122, India., Kumari P; Division of Parasitology, ICAR-Indian Veterinary Research Institute, Izatnagar, Uttar Pradesh, 243122, India., Kundave VR; Division of Parasitology, ICAR-Indian Veterinary Research Institute, Izatnagar, Uttar Pradesh, 243122, India., Singh M; Immunology Section, ICAR-Indian Veterinary Research Institute, Izatnagar, Uttar Pradesh, 243122, India., Banerjee PS; Division of Parasitology, ICAR-Indian Veterinary Research Institute, Izatnagar, Uttar Pradesh, 243122, India.

المصدر: Parasitology research [Parasitol Res] 2019 Mar; Vol. 118 (3), pp. 945-953. Date of Electronic Publication: 2019 Jan 13.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Springer International Country of Publication: Germany NLM ID: 8703571 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1955 (Electronic) Linking ISSN: 09320113 NLM ISO Abbreviation: Parasitol Res Subsets: MEDLINE

مواضيع طبية MeSH: Chickens*, Antigens, Protozoan/*immunology , Coccidiosis/*veterinary , Eimeria tenella/*immunology , Poultry Diseases/*parasitology , Protozoan Vaccines/*immunology, Adjuvants, Immunologic ; Animals ; Cecum ; Coccidiosis/prevention & control ; Cytokines ; Immunization ; Poultry Diseases/prevention & control ; Recombinant Proteins ; Vaccination ; Vaccines, Subunit