المؤلفون: Constan AA; Chemical Industry Institute of Toxicology, Research Triangle Park, North Carolina, 27709-2137, USA., Sprankle CS, Peters JM, Kedderis GL, Everitt JI, Wong BA, Gonzalez FL, Butterworth BE

المصدر: Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 1999 Oct 15; Vol. 160 (2), pp. 120-6.

نوع المنشور: Comparative Study; Journal Article

بيانات الدورية: Publisher: Academic Press Country of Publication: United States NLM ID: 0416575 Publication Model: Print Cited Medium: Print ISSN: 0041-008X (Print) Linking ISSN: 0041008X NLM ISO Abbreviation: Toxicol Appl Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Carcinogens/*toxicity , Chloroform/*toxicity , Cytochrome P-450 CYP2E1/*metabolism , Kidney/*drug effects , Liver/*drug effects , Nose/*drug effects, Administration, Inhalation ; Animals ; Biotransformation ; Cell Division ; Chloroform/administration & dosage ; Chloroform/pharmacokinetics ; Cytochrome P-450 CYP2E1/genetics ; Cytochrome P-450 CYP2E1 Inhibitors ; Immunohistochemistry ; Kidney/enzymology ; Kidney/pathology ; Liver/enzymology ; Liver/pathology ; Male ; Mice ; Mice, Inbred Strains ; Mice, Knockout ; Necrosis ; Organ Size ; Turbinates/drug effects ; Turbinates/enzymology ; Turbinates/pathology

المؤلفون: Butterworth BE; Chemical Industry Institute of Toxicology, Research Triangle Park, North Carolina 27709, USA. butterworth@ciit.org, Templin MV, Constan AA, Sprankle CS, Wong BA, Pluta LJ, Everitt JI, Recio L

المصدر: Environmental and molecular mutagenesis [Environ Mol Mutagen] 1998; Vol. 31 (3), pp. 248-56.

نوع المنشور: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

بيانات الدورية: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8800109 Publication Model: Print Cited Medium: Print ISSN: 0893-6692 (Print) Linking ISSN: 08936692 NLM ISO Abbreviation: Environ Mol Mutagen Subsets: MEDLINE

مواضيع طبية MeSH: Chloroform/*toxicity , Dimethylnitrosamine/*toxicity , Lac Operon/*drug effects , Liver/*drug effects , Liver Neoplasms, Experimental/*chemically induced , Transgenes/*drug effects, Administration, Inhalation ; Administration, Oral ; Animals ; Chemical and Drug Induced Liver Injury ; Dose-Response Relationship, Drug ; Female ; Liver/pathology ; Liver Diseases/genetics ; Liver Diseases/pathology ; Liver Neoplasms, Experimental/genetics ; Liver Neoplasms, Experimental/pathology ; Liver Regeneration ; Mice ; Mice, Transgenic ; Organ Size/drug effects ; Precancerous Conditions/chemically induced ; Precancerous Conditions/genetics ; Precancerous Conditions/pathology

المؤلفون: Templin MV; Chemical Industry Institute of Toxicology, Research Triangle Park, NC 27709-2137, USA., Constan AA, Wolf DC, Wong BA, Butterworth BE

المصدر: Carcinogenesis [Carcinogenesis] 1998 Jan; Vol. 19 (1), pp. 187-93.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Irl Press At Oxford University Press Country of Publication: England NLM ID: 8008055 Publication Model: Print Cited Medium: Print ISSN: 0143-3334 (Print) Linking ISSN: 01433334 NLM ISO Abbreviation: Carcinogenesis Subsets: MEDLINE

مواضيع طبية MeSH: Carcinogens/*toxicity , Chloroform/*toxicity , Liver/*drug effects , Liver Neoplasms/*chemically induced , Liver Regeneration/*drug effects, Adenoma/chemically induced ; Adenoma/pathology ; Animals ; Body Weight/drug effects ; Carcinoma/chemically induced ; Carcinoma/pathology ; Cell Division/drug effects ; Dose-Response Relationship, Drug ; Female ; Liver/pathology ; Liver/physiology ; Liver Neoplasms/pathology ; Male ; Mice ; Organ Size/drug effects ; Sex Characteristics ; Time Factors

المؤلفون: Michael V. Templin, Alexander A. Constan, Brian A. Wong, Byron E. Butterworth, Douglas C. Wolf

المصدر: Carcinogenesis. 19:187-193

مصطلحات موضوعية: Adenoma, Male, Cancer Research, medicine.medical_specialty, Time Factors, No-observed-adverse-effect level, Renal cortex, Biology, medicine.disease_cause, Mice, Internal medicine, medicine, Animals, Carcinogen, Sex Characteristics, Kidney, Dose-Response Relationship, Drug, Cell growth, Body Weight, Carcinoma, Liver Neoplasms, Organ Size, General Medicine, Liver Regeneration, Endocrinology, medicine.anatomical_structure, Liver, Hepatocyte, Toxicity, Carcinogens, Female, Chloroform, Carcinogenesis, Cell Division

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::007321e5304c1944652b019fcb393a24
https://doi.org/10.1093/carcin/19.1.187

المؤلفون: Byron E. Butterworth, Brian A. Wong, Jeffrey I. Everitt, Alexander A. Constan

المصدر: Toxicological sciences : an official journal of the Society of Toxicology. 66(2)

مصطلحات موضوعية: Physiologically based pharmacokinetic modelling, Time Factors, Mice, Inbred Strains, Pharmacology, Toxicology, Models, Biological, chemistry.chemical_compound, Mice, Pharmacokinetics, Administration, Inhalation, medicine, Animals, Carcinogen, Inhalation exposure, Inhalation, Cell Death, Dose-Response Relationship, Drug, Organ Size, medicine.anatomical_structure, chemistry, Liver, Hepatocyte, Toxicity, Carcinogens, Solvents, Female, Chloroform, Bromodeoxyuridine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3db8bbf26c19126d7d86c4054a220e1f
https://pubmed.ncbi.nlm.nih.gov/11896286

المؤلفون: Byron E. Butterworth, Frank L. Gonzalez, Gregory L. Kedderis, Brian A. Wong, Catherine S. Sprankle, Jeffrey I. Everitt, Alexander A. Constan, Jeffrey M. Peters

المصدر: Toxicology and applied pharmacology. 160(2)

مصطلحات موضوعية: Male, medicine.medical_specialty, Necrosis, Mice, Inbred Strains, Biology, Nose, Toxicology, Kidney, Turbinates, chemistry.chemical_compound, Mice, Internal medicine, Administration, Inhalation, medicine, Animals, Carcinogen, Biotransformation, Pharmacology, Mice, Knockout, Cell growth, Cytochrome P450, Cytochrome P-450 CYP2E1, Organ Size, CYP2E1, Immunohistochemistry, Cytochrome P-450 CYP2E1 Inhibitors, medicine.anatomical_structure, Endocrinology, chemistry, Liver, Toxicity, biology.protein, Carcinogens, Chloroform, medicine.symptom, Cell Division, Toxicant

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2f114a6d2cd445c1a630f615e7234fa
https://pubmed.ncbi.nlm.nih.gov/10527910

المؤلفون: Stephen A. Benjamin, Dale C. Baker, Raymond S. H. Yang, Alexander A. Constan

المصدر: Carcinogenesis. 16(2)

مصطلحات موضوعية: Chromium, Male, Cancer Research, Time Factors, Trichloroethylene, Mitosis, Mutagen, Fresh Water, Pharmacology, medicine.disease_cause, Hazardous Substances, Arsenic, Toxicology, chemistry.chemical_compound, Liver Neoplasms, Experimental, Phenols, Oral administration, medicine, Animals, Carcinogen, chemistry.chemical_classification, biology, Dose-Response Relationship, Drug, Phenol, Chemistry, Benzene, General Medicine, Enzyme assay, Rats, Inbred F344, Rats, medicine.anatomical_structure, Enzyme, Lead, Liver, Hepatocyte, Toxicity, biology.protein, Chloroform, Cell Division, Water Pollutants, Chemical

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::984fe85f2e5d34764b19509bdef680f5
https://pubmed.ncbi.nlm.nih.gov/7859362

المؤلفون: Byron E. Butterworth, Catherine S. Sprankle, Michael V. Templin, Alex Constan, Douglas C. Wolf, Brian A. Wong, Linda J. Pluta, Leslie Recio

المصدر: Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 379:S148

مصطلحات موضوعية: chemistry.chemical_compound, Chloroform, chemistry, Health, Toxicology and Mutagenesis, Transgene, Genetics, Lac repressor, Molecular Biology, Molecular biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::764a79caa5ace8c968f3ec0f1b163444
https://doi.org/10.1016/s0027-5107(97)83129-6

المؤلفون: Constan, Alexander A., Wong, Brian A., Everitt, Jeffrey I., Butterworth, Byron E.

المصدر: Toxicological Sciences; Apr2002, Vol. 66 Issue 2, p201-208, 8p, 1 Diagram, 3 Charts, 1 Graph

مصطلحات موضوعية: CHLOROFORM, CARCINOGENS, LIVER, CELL proliferation, MICE