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1دورية أكاديمية
المؤلفون: Sevrioukova, Irina
المصدر: Journal of Biological Chemistry. 299(9)
مصطلحات موضوعية: CYP3A4, caffeine, complex, crystal structure, cytochrome P450, ligand-binding protein, spectroscopy, Humans, Binding Sites, Caffeine, Catalytic Domain, Cytochrome P-450 CYP3A, Ligands, Substrate Specificity, Protein Binding, Allosteric Regulation, Crystallography, X-Ray, Crystallization, Demethylation, Heme, Hydrophobic and Hydrophilic Interactions, Mutation
وصف الملف: application/pdf
URL الوصول: https://escholarship.org/uc/item/904871hv
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2دورية أكاديمية
المؤلفون: Reininger, Kevin, Onyeaghala, Guillaume, Anderson-Haag, Teresa, Schladt, David, Wu, Baolin, Guan, Weihua, Dorr, Casey, Remmel, Rory, Mannon, Roslyn, Matas, Arthur, Oetting, William, Stahler, Paul, Israni, Ajay, Jacobson, Pamala
المصدر: Clinical Transplantation. 37(4)
مصطلحات موضوعية: CYP3A5, clinical management, kidney transplants, tacrolimus, Humans, Tacrolimus, Immunosuppressive Agents, Kidney Transplantation, Cytochrome P-450 CYP3A, Genotype, Transplant Recipients, Polymorphism, Single Nucleotide
وصف الملف: application/pdf
URL الوصول: https://escholarship.org/uc/item/3np5m057
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3دورية أكاديمية
المؤلفون: Denison, Madeline, Ahrens, Justin J, Dunbar, Marilyn N, Warmahaye, Habon, Majeed, Aliza, Turro, Claudia, Kocarek, Thomas A, Sevrioukova, Irina F, Kodanko, Jeremy J
المصدر: Inorganic Chemistry. 62(7)
مصطلحات موضوعية: Medicinal and Biomolecular Chemistry, Chemical Sciences, 5.1 Pharmaceuticals, Development of treatments and therapeutic interventions, Generic health relevance, Humans, Cytochrome P-450 CYP3A, Cytochrome P-450 Enzyme System, Drug Interactions, Structure-Activity Relationship, Inorganic Chemistry, Physical Chemistry (incl. Structural), Other Chemical Sciences, Inorganic & Nuclear Chemistry, Inorganic chemistry, Macromolecular and materials chemistry
وصف الملف: application/pdf
URL الوصول: https://escholarship.org/uc/item/1435n95g
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4دورية أكاديمية
المؤلفون: Witta, Sandra, Collins, Keagan P, Ramirez, Dominique A, Mannheimer, Joshua D, Wittenburg, Luke A, Gustafson, Daniel L
المصدر: Pharmacology Research & Perspectives. 11(1)
مصطلحات موضوعية: Pharmacology and Pharmaceutical Sciences, Biomedical and Clinical Sciences, Humans, Dogs, Mice, Animals, Vinblastine, Cytochrome P-450 CYP3A, Antineoplastic Agents, Drug Interactions, Biological Transport, comparative oncology, physiologically-based pharmacokinetic modeling, vinblastine, Medicinal and Biomolecular Chemistry, Pharmacology and pharmaceutical sciences
وصف الملف: application/pdf
URL الوصول: https://escholarship.org/uc/item/5cq7s30d
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5دورية أكاديمية
المؤلفون: Sevrioukova, Irina
المصدر: International Journal of Molecular Sciences. 23(20)
مصطلحات موضوعية: CYP3A4, crystal structure, fluorol, substrate binding, Humans, Cytochrome P-450 CYP3A, Ligands, Fluorescent Dyes, Binding Sites, Kinetics
وصف الملف: application/pdf
URL الوصول: https://escholarship.org/uc/item/47n4p7rg
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6دورية أكاديمية
المؤلفون: Denison, Madeline, Steinke, Sean, Majeed, Aliza, Turro, Claudia, Kocarek, Thomas, Sevrioukova, Irina, Kodanko, Jeremy
المصدر: Inorganic Chemistry. 61(35)
مصطلحات موضوعية: Catalytic Domain, Cytochrome P-450 CYP3A, Cytochrome P-450 Enzyme System, Heme, Humans, Iridium
وصف الملف: application/pdf
URL الوصول: https://escholarship.org/uc/item/0w04q646
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7دورية أكاديمية
المؤلفون: Liu, Shuaibing, Sodhi, Jasleen K, Benet, Leslie Z
المصدر: Pharmaceutical Research. 38(10)
مصطلحات موضوعية: Pharmacology and Pharmaceutical Sciences, Biomedical and Clinical Sciences, Substance Misuse, Clinical Research, Digestive Diseases, Drug Abuse (NIDA only), ATP Binding Cassette Transporter, Subfamily B, Member 1, Citrus paradisi, Cyclosporine, Cytochrome P-450 CYP3A, Cytochrome P-450 CYP3A Inhibitors, Diltiazem, Drug Interactions, Fruit and Vegetable Juices, Humans, Intestinal Absorption, Intestines, Ketoconazole, Rifampin, Ticagrelor, drug-drug interactions, mean absorption time, ticagrelor, Pharmacology & Pharmacy, Pharmacology and pharmaceutical sciences
وصف الملف: application/pdf
URL الوصول: https://escholarship.org/uc/item/824025xc
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8دورية أكاديمية
المؤلفون: Toupin, Nicholas, Steinke, Sean, Nadella, Sandeep, Li, Ao, Rohrabaugh, Thomas, Samuels, Eric, Turro, Claudia, Sevrioukova, Irina, Kodanko, Jeremy
المصدر: Journal of the American Chemical Society. 143(24)
مصطلحات موضوعية: Antineoplastic Agents, Cell Line, Tumor, Cell Proliferation, Cell Survival, Coordination Complexes, Cytochrome P-450 CYP3A, Cytochrome P-450 CYP3A Inhibitors, Drug Screening Assays, Antitumor, Humans, Models, Molecular, Molecular Structure, Photosensitizing Agents, Ruthenium
وصف الملف: application/pdf
URL الوصول: https://escholarship.org/uc/item/8dx9z9c9
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9دورية أكاديمية
المؤلفون: Samuels, Eric R, Sevrioukova, Irina F
المصدر: International Journal of Molecular Sciences. 22(2)
مصطلحات موضوعية: Medicinal and Biomolecular Chemistry, Chemical Sciences, Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, Binding Sites, Cytochrome P-450 CYP3A, Cytochrome P-450 CYP3A Inhibitors, Drug Design, Humans, Molecular Docking Simulation, Protein Binding, Quantitative Structure-Activity Relationship, Ritonavir, ligand binding, inhibitor design, crystal structure, structure–, activity relations, surface mutation, CYP3A4, structure–activity relations, Other Chemical Sciences, Genetics, Other Biological Sciences, Chemical Physics, Biochemistry and cell biology, Microbiology, Medicinal and biomolecular chemistry
وصف الملف: application/pdf
URL الوصول: https://escholarship.org/uc/item/5p9431tn
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10دورية أكاديمية
المؤلفون: Paquin, Alexis, Oufqir, Yassine, Sevrioukova, Irina F, Reyes-Moreno, Carlos, Bérubé, Gervais
مصطلحات موضوعية: Biomedical and Clinical Sciences, Chemical Sciences, Oncology and Carcinogenesis, Prostate Cancer, Cancer, Urologic Diseases, Aging, Androstenedione, Antineoplastic Agents, Cell Proliferation, Cell Survival, Cytochrome P-450 CYP3A, Dimerization, Dose-Response Relationship, Drug, Drug Design, Drug Screening Assays, Antitumor, Humans, Male, Molecular Structure, Prostatic Neoplasms, Recombinant Proteins, Structure-Activity Relationship, Testosterone, Tumor Cells, Cultured, CYP3A4, Dihydrotestosterone, Dimers, Medicinal and Biomolecular Chemistry, Organic Chemistry, Pharmacology and Pharmaceutical Sciences, Medicinal & Biomolecular Chemistry, Pharmacology and pharmaceutical sciences, Medicinal and biomolecular chemistry, Organic chemistry
وصف الملف: application/pdf
URL الوصول: https://escholarship.org/uc/item/6n29v719