نتائج البحث - "Cytochrome P-450 CYP3A"

1

High Intrapatient Variability in Tacrolimus Exposure Calculated Over a Long Period Is Associated With De Novo Donor-Specific Antibody Development and/or Late Rejection in Thai Kidney Transplant Patients Receiving Concomitant CYP3A4/5 Inhibitors

المؤلفون: N. Premasathian, Tanapon Pongnatcha, A. Vongwiwatana, Pera Panprom, Ratchawat Promraj, Nuttasith Larpparisuth

المصدر: Therapeutic Drug Monitoring. 43:624-629

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df56face542cfd5929f95cde95f3ecae
https://doi.org/10.1097/ftd.0000000000000850

2

Pharmacoenhancement of Low Crizotinib Plasma Concentrations in Patients with Anaplastic Lymphoma Kinase‐Positive Non‐Small Cell Lung Cancer using the CYP3A Inhibitor Cobicistat

المؤلفون: Farastuk Bozorgmehr, Antje Blank, Walter E. Haefeli, Michael Thomas, Petros Christopoulos, Jürgen Burhenne, Nicolas Hohmann, Gerd Mikus

المصدر: Clinical and Translational Science, Vol 14, Iss 2, Pp 487-491 (2021)
Clinical and Translational Science

مصطلحات موضوعية: Adult, Male, Alectinib, medicine.medical_specialty, Lung Neoplasms, Cost-Benefit Analysis, Gastroenterology, General Biochemistry, Genetics and Molecular Biology, Cmin, Crizotinib, Pharmacokinetics, Carcinoma, Non-Small-Cell Lung, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Cytochrome P-450 CYP3A, Humans, Outpatient clinic, Anaplastic lymphoma kinase, Anaplastic Lymphoma Kinase, General Pharmacology, Toxicology and Pharmaceutics, Lung cancer, Protein Kinase Inhibitors, Dose-Response Relationship, Drug, business.industry, Brief Report, Research, General Neuroscience, Cobicistat, lcsh:Public aspects of medicine, lcsh:RM1-950, Drug Synergism, lcsh:RA1-1270, General Medicine, Middle Aged, medicine.disease, lcsh:Therapeutics. Pharmacology, Mutation, Cytochrome P-450 CYP3A Inhibitors, Feasibility Studies, Female, Brief Reports, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce54c3f30d557ad7a897cb02d2f1b58a
https://doaj.org/article/c3263b190a004989afea2f5553ef2b93

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3

CYP3A-status is associated with blood concentration and dose-requirement of tacrolimus in heart transplant recipients

المؤلفون: Katalin Mangó, Máté Déri, Balázs Sax, Ferenc Fekete, Katalin Monostory, Béla Merkely, Zsófia Szakál-Tóth, Evelyn Incze, Annamária Minus

المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::307ad034f1ef1790f385147b129e2a43
https://doaj.org/article/432193eb97624b7c9b53b30747e53717

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4

Impact of Cilostazol Pharmacokinetics on the Development of Cardiovascular Side Effects in Patients with Cerebral Infarction

المؤلفون: Toshio Maeda, Keishi Yamagata, Yoshinori Asahara, Yoshiyuki Kagawa, Tasuku Yokoyama, Yumiko Urano, Yuta Kaneshiro, Shigeru Yamauchi, Keiji Murata

المصدر: Biological and Pharmaceutical Bulletin. 44:1767-1774

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53132e66f52086c3daf26db9a9df6aad
https://doi.org/10.1248/bpb.b21-00535

5

Population pharmacokinetic and exposure‐response analyses of ivosidenib in patients with IDH1‐mutant advanced hematologic malignancies

المؤلفون: Russ Wada, Stephanie M. Kapsalis, Bill Poland, Xuemin Jiang, Guowen Liu, Bin Fan, Huub Jan Kleijn, Hua Liu, Kha Le, Hua Yang

المصدر: Clinical and Translational Science
Clinical and Translational Science, Vol 14, Iss 3, Pp 942-953 (2021)

مصطلحات موضوعية: Male, 030213 general clinical medicine, Pyridines, Administration, Oral, 030226 pharmacology & pharmacy, Gastroenterology, Electrocardiography, 0302 clinical medicine, Medicine, Cytochrome P-450 CYP3A, Drug Interactions, Tissue Distribution, General Pharmacology, Toxicology and Pharmaceutics, Aged, 80 and over, education.field_of_study, General Neuroscience, Myeloid leukemia, General Medicine, Articles, Middle Aged, Isocitrate Dehydrogenase, Leukemia, Myeloid, Acute, Long QT Syndrome, Isocitrate dehydrogenase, Treatment Outcome, Area Under Curve, Female, Public aspects of medicine, RA1-1270, Adult, medicine.medical_specialty, Adolescent, Population, Glycine, Antineoplastic Agents, RM1-950, QT interval, Models, Biological, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Young Adult, Refractory, Pharmacokinetics, Internal medicine, Humans, Adverse effect, education, Aged, CYP3A4, business.industry, Research, Biological Variation, Population, Mutation, Cytochrome P-450 CYP3A Inhibitors, Therapeutics. Pharmacology, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47d81c9c6bb18874780e88db514c6ba9
http://europepmc.org/articles/PMC8212730

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6

Pharmacokinetics of a once‐daily tacrolimus formulation in first nations and caucasian liver transplant recipients

المؤلفون: Ngoc H. On, Gerald Y. Minuk, Donald W. Miller, Cori Knowles, Carla Franklin, Roman Dascal, David Peretz, Richard B. Kim

المصدر: Transplant International. 34:2266-2273

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15ea0e979a70d7cbb649d559543c59f1
https://doi.org/10.1111/tri.13997

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7

Unraveling the Genomic Architecture of the CYP3A Locus and ADME Genes for Personalized Tacrolimus Dosing

المؤلفون: Sang Il Min, Sanghoon Moon, Jae Berm Park, In-Jin Jang, Hyo Kee Kim, Ho Sik Shin, Seung Hwan Song, Sungkyoung Choi, Young-Jin Kim, Jihoon G. Yoon, Yuri Cho, Myoung Soo Kim, Min Goo Lee, Hye Eun Yoon, Bong-Jo Kim, Jaeseong Oh, Jongwon Ha, Jaeseok Yang, Chul Woo Yang

المصدر: Transplantation. 105:2213-2225

مصطلحات موضوعية: Adult, Graft Rejection, Male, Oncology, medicine.medical_specialty, Adolescent, Pharmacogenomic Variants, Clinical Decision-Making, Locus (genetics), Genome-wide association study, Risk Assessment, Tacrolimus, Young Adult, Pharmacokinetics, Predictive Value of Tests, Risk Factors, Internal medicine, Republic of Korea, medicine, Cytochrome P-450 CYP3A, Humans, Precision Medicine, CYP3A5, Aged, Retrospective Studies, ADME, Aged, 80 and over, Transplantation, business.industry, Graft Survival, Haplotype, Confounding, Middle Aged, Kidney Transplantation, Pharmacogenomic Testing, Cross-Sectional Studies, Treatment Outcome, Haplotypes, Pharmacogenetics, Female, business, Immunosuppressive Agents, Genome-Wide Association Study

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a0ee06d158342af2344df56c0f8d50e
https://doi.org/10.1097/tp.0000000000003660

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The effect of carbamazepine, which increases oestrogen destruction, on the endometriotic implants; an experimental rat model

المؤلفون: Mehmet Bülbül, Bilge Aydın Türk, Talip Karaçor, Mehmet Can Nacar, Ali Parlar, Cihat Ucar, Pınar Kirici, Muhittin Onderci

المصدر: Journal of Obstetrics and Gynaecology. 42:1261-1267

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f050b09fd0b51388c78999bdf045286f
https://doi.org/10.1080/01443615.2021.1953453

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9

Severe adverse cutaneous reactions induced by gefitinib combined with antihypertensive and antihyperlipidemic drugs in lung cancer: a case report

المؤلفون: Jiguang Lu, Xiao Shen, Hong Zhu, Ying Zhu, Qi Li, Xinyan Liu, Fan Wang, Guorong Fan, Shuowen Wang, Gaolin Liu

المصدر: Anti-Cancer Drugs

مصطلحات موضوعية: Drug, Cancer Research, medicine.medical_specialty, Lung Neoplasms, therapeutic drug monitoring, media_common.quotation_subject, medicine.medical_treatment, gefitinib, plasma concentration, Adenocarcinoma of Lung, Antineoplastic Agents, Hyperlipidemias, Case Reports, Gefitinib, Internal medicine, Hyperlipidemia, medicine, Cytochrome P-450 CYP3A, Humans, case report, Pharmacology (medical), drug–drug interaction, Lung cancer, Antihypertensive Agents, Hypolipidemic Agents, media_common, Pharmacology, Chemotherapy, medicine.diagnostic_test, business.industry, Cancer, Middle Aged, medicine.disease, Oncology, Therapeutic drug monitoring, Lymphatic Metastasis, Hypertension, Adenocarcinoma, Female, Drug Eruptions, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23322452189af81aab9ce9c99e40b161
https://doi.org/10.1097/cad.0000000000001226

10

Effects of CPY3A5 Genetic Polymorphisms on the Pharmacokinetics of Extendedrelease and Immediate-release Tacrolimus Formulations in Renal Transplant Recipients: A Systematic Review and Meta-analysis

المؤلفون: Zhuo Zhang, Shuang Zhou, Yimin Cui, Zhiyan Liu, Qian Xiang, Guangyan Mu, Qiufen Xie, Lingyue Ma

المصدر: Current Drug Metabolism. 22:758-771

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfdd80a1edef3414be6351857bb6c11e
https://doi.org/10.2174/1389200222666210825160021

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