المؤلفون: Nikitaki Z; Department of Physics, School of Applied Mathematical and Physical Sciences, National Technical University of Athens (NTUA), Zografou Campus, 15780Athens, Greece., Velalopoulou A; Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, 19104USA., Zanni V; Department of Physics, School of Applied Mathematical and Physical Sciences, National Technical University of Athens (NTUA), Zografou Campus, 15780Athens, Greece., Tremi I; Department of Physics, School of Applied Mathematical and Physical Sciences, National Technical University of Athens (NTUA), Zografou Campus, 15780Athens, Greece.; Molecular Carcinogenesis Group, Department of Histology and Embryology, School of Medicine, National and Kapodistrian University of Athens, 11527Athens, Greece., Havaki S; Molecular Carcinogenesis Group, Department of Histology and Embryology, School of Medicine, National and Kapodistrian University of Athens, 11527Athens, Greece., Kokkoris M; Department of Physics, School of Applied Mathematical and Physical Sciences, National Technical University of Athens (NTUA), Zografou Campus, 15780Athens, Greece., Gorgoulis VG; Molecular Carcinogenesis Group, Department of Histology and Embryology, School of Medicine, National and Kapodistrian University of Athens, 11527Athens, Greece.; Biomedical Research Foundation, Academy of Athens, Athens, Greece.; Faculty Institute for Cancer Sciences, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, UK.; Center for New Biotechnologies and Precision Medicine, Medical School, National and Kapodistrian University of Athens, Athens, Greece.; Faculty of Health and Medical Sciences, University of Surrey, Surrey, UK., Koumenis C; Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, 19104USA., Georgakilas AG; Department of Physics, School of Applied Mathematical and Physical Sciences, National Technical University of Athens (NTUA), Zografou Campus, 15780Athens, Greece.

المصدر: Expert reviews in molecular medicine [Expert Rev Mol Med] 2022 Mar 31; Vol. 24, pp. e15. Date of Electronic Publication: 2022 Mar 31.

نوع المنشور: Journal Article; Review; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Published by Cambridge University Press in association with the Clinical and Biomedical Computing Unit of the University of Cambridge School of Clinical Medicine Country of Publication: England NLM ID: 100939725 Publication Model: Electronic Cited Medium: Internet ISSN: 1462-3994 (Electronic) Linking ISSN: 14623994 NLM ISO Abbreviation: Expert Rev Mol Med Subsets: MEDLINE

مواضيع طبية MeSH: Boron Neutron Capture Therapy* , DNA Damage*, DNA Repair ; Humans ; Linear Energy Transfer ; Radiation, Ionizing

المؤلفون: Pietrofesa RA; Division of Pulmonary, Allergy, and Critical Care Medicine and the Department of Medicine, University of Pennsylvania Perelman School of Medicine, 3450 Hamilton Walk, Edward J. Stemmler Hall 2nd Floor, Office Suite 227, Philadelphia, PA 19104, USA. ralphp@mail.med.upenn.edu., Velalopoulou A; Division of Pulmonary, Allergy, and Critical Care Medicine and the Department of Medicine, University of Pennsylvania Perelman School of Medicine, 3450 Hamilton Walk, Edward J. Stemmler Hall 2nd Floor, Office Suite 227, Philadelphia, PA 19104, USA. avela@mail.med.upenn.edu., Lehman SL; Department of Radiation Oncology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA. staceylehman87@gmail.com., Arguiri E; Division of Pulmonary, Allergy, and Critical Care Medicine and the Department of Medicine, University of Pennsylvania Perelman School of Medicine, 3450 Hamilton Walk, Edward J. Stemmler Hall 2nd Floor, Office Suite 227, Philadelphia, PA 19104, USA. evguenia@mail.med.upenn.edu., Solomides P; Division of Pulmonary, Allergy, and Critical Care Medicine and the Department of Medicine, University of Pennsylvania Perelman School of Medicine, 3450 Hamilton Walk, Edward J. Stemmler Hall 2nd Floor, Office Suite 227, Philadelphia, PA 19104, USA. pantelis.solomides@temple.edu., Koch CJ; Department of Radiation Oncology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA. kochc@mail.med.upenn.edu., Mishra OP; Division of Pulmonary, Allergy, and Critical Care Medicine and the Department of Medicine, University of Pennsylvania Perelman School of Medicine, 3450 Hamilton Walk, Edward J. Stemmler Hall 2nd Floor, Office Suite 227, Philadelphia, PA 19104, USA. mishra.o@gmail.com., Koumenis C; Department of Radiation Oncology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA. costas.Koumenis@uphs.upenn.edu., Goodwin TJ; The National Aeronautics and Space Administration (NASA) Johnson Space Center, Houston, TX 77058, USA. tgoodwin3@comcast.net., Christofidou-Solomidou M; Division of Pulmonary, Allergy, and Critical Care Medicine and the Department of Medicine, University of Pennsylvania Perelman School of Medicine, 3450 Hamilton Walk, Edward J. Stemmler Hall 2nd Floor, Office Suite 227, Philadelphia, PA 19104, USA. melpo@mail.med.upenn.edu.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2016 Jun 16; Vol. 17 (6). Date of Electronic Publication: 2016 Jun 16.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: DNA Damage* , Hyperoxia* , Models, Biological* , Oxidative Stress* , Radiation, Ionizing* , Space Flight*, Alveolar Epithelial Cells/metabolism ; Alveolar Epithelial Cells/radiation effects ; Animals ; Antioxidants/metabolism ; Apoptosis/genetics ; Apoptosis/radiation effects ; Cell Cycle/genetics ; Cell Cycle/radiation effects ; Cell Survival/genetics ; Cell Survival/radiation effects ; Gene Expression Regulation/radiation effects ; Gene Expression Regulation, Enzymologic ; Histones/metabolism ; Humans ; Mice ; Oxidation-Reduction ; Phosphorylation ; Reactive Oxygen Species/metabolism ; Signal Transduction

المؤلفون: Stewart RD; Department of Radiation Oncology, University of Washington, Seattle, Washington 98195-6043, USA. trawets@uw.edu, Yu VK, Georgakilas AG, Koumenis C, Park JH, Carlson DJ

المصدر: Radiation research [Radiat Res] 2011 Nov; Vol. 176 (5), pp. 587-602. Date of Electronic Publication: 2011 Aug 08.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Radiation Research Society Country of Publication: United States NLM ID: 0401245 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1938-5404 (Electronic) Linking ISSN: 00337587 NLM ISO Abbreviation: Radiat Res Subsets: MEDLINE

مواضيع طبية MeSH: DNA Damage* , Monte Carlo Method*, Oxygen/*metabolism, Cell Death/radiation effects ; Cell Hypoxia/radiation effects ; Cell Line ; Cell Survival/radiation effects ; DNA Breaks, Double-Stranded/radiation effects ; Humans ; Iron/adverse effects ; Kinetics ; Linear Energy Transfer/radiation effects ; Protons/adverse effects ; Relative Biological Effectiveness

المؤلفون: Bobrovnikova-Marjon E; The Leonard and Madlyn Abramson Family Cancer Research Institute and Cancer Center, University of Pennsylvania, Philadelphia, PA, USA., Grigoriadou C, Pytel D, Zhang F, Ye J, Koumenis C, Cavener D, Diehl JA

المصدر: Oncogene [Oncogene] 2010 Jul 08; Vol. 29 (27), pp. 3881-95. Date of Electronic Publication: 2010 May 10.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5594 (Electronic) Linking ISSN: 09509232 NLM ISO Abbreviation: Oncogene Subsets: MEDLINE

مواضيع طبية MeSH: DNA Damage* , Oxidative Stress*, Neoplasms/*enzymology , Neoplasms/*pathology , eIF-2 Kinase/*metabolism, Animals ; Antigens, Viral, Tumor/genetics ; Cell Cycle/genetics ; Cell Line, Tumor ; Cell Proliferation ; Female ; Gene Knockdown Techniques ; Humans ; Inverted Repeat Sequences ; Male ; Mammary Glands, Animal/metabolism ; Mammary Glands, Animal/pathology ; Mammary Neoplasms, Experimental/genetics ; Mammary Neoplasms, Experimental/metabolism ; Mammary Neoplasms, Experimental/pathology ; Mice ; NF-E2-Related Factor 2/metabolism ; Neoplasms/genetics ; Neoplasms/metabolism ; Organ Specificity ; RNA, Small Interfering/genetics ; Reactive Oxygen Species/metabolism ; Viral Core Proteins/genetics ; eIF-2 Kinase/deficiency ; eIF-2 Kinase/genetics

المؤلفون: Hart LS; Department of Radiation Oncology, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, USA., Ornelles D, Koumenis C

المصدر: The Journal of biological chemistry [J Biol Chem] 2007 Mar 02; Vol. 282 (9), pp. 6061-7. Date of Electronic Publication: 2006 Dec 15.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Print ISSN: 0021-9258 (Print) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

مواضيع طبية MeSH: Apoptosis* , DNA Damage*, Adenovirus E4 Proteins/*physiology , Adenoviruses, Human/*pathogenicity , Poly(ADP-ribose) Polymerases/*metabolism, Adenoviruses, Human/chemistry ; Apoptosis Inducing Factor/metabolism ; Cell Line ; DNA-Activated Protein Kinase ; Histones/metabolism ; Humans ; Phosphoprotein Phosphatases/antagonists & inhibitors ; Phosphorylation ; Protein Phosphatase 2 ; Signal Transduction

المؤلفون: Hart LS; Department of Radiation Oncology, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, USA., Yannone SM, Naczki C, Orlando JS, Waters SB, Akman SA, Chen DJ, Ornelles D, Koumenis C

المصدر: The Journal of biological chemistry [J Biol Chem] 2005 Jan 14; Vol. 280 (2), pp. 1474-81. Date of Electronic Publication: 2004 Oct 26.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Print ISSN: 0021-9258 (Print) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

مواضيع طبية MeSH: DNA Repair* , Radiation Tolerance*, Adenoviridae/*physiology , Adenovirus E1B Proteins/*metabolism , Adenovirus E4 Proteins/*metabolism , DNA Damage/*radiation effects , Open Reading Frames/*genetics, Adenoviridae/genetics ; Adenovirus E4 Proteins/genetics ; Cell Line, Tumor ; DNA-Activated Protein Kinase ; DNA-Binding Proteins/metabolism ; Humans ; Models, Biological ; Mutation/genetics ; Nuclear Proteins ; Phosphorylation ; Protein Serine-Threonine Kinases/metabolism ; Radiation, Ionizing ; Threonine/genetics ; Threonine/metabolism ; Transduction, Genetic

المؤلفون: Fried LM; Department of Radiation Oncology, Stanford University School of Medicine, CA 94305, USA., Koumenis C, Peterson SR, Green SL, van Zijl P, Allalunis-Turner J, Chen DJ, Fishel R, Giaccia AJ, Brown JM, Kirchgessner CU

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 1996 Nov 26; Vol. 93 (24), pp. 13825-30.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print Cited Medium: Print ISSN: 0027-8424 (Print) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: DNA Damage* , DNA Replication*, DNA-Binding Proteins/*metabolism , Protein Serine-Threonine Kinases/*deficiency , Tumor Suppressor Protein p53/*biosynthesis, Animals ; Cell Line ; DNA-Activated Protein Kinase ; Fibroblasts/physiology ; Fibroblasts/radiation effects ; Glioblastoma ; Humans ; Mice ; Mice, SCID ; Nuclear Proteins ; Oligodeoxyribonucleotides ; Phosphorylation ; Protein Serine-Threonine Kinases/metabolism ; Replication Protein A ; Substrate Specificity ; Tumor Cells, Cultured

المؤلفون: Girinsky T; Department of Radiation Oncology, Institut Gustave-Roussy, Villejuif, France., Koumenis C, Graeber TG, Peehl DM, Giaccia AJ

المصدر: Cancer research [Cancer Res] 1995 Sep 01; Vol. 55 (17), pp. 3726-31.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print Cited Medium: Print ISSN: 0008-5472 (Print) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: DNA Damage*, Adenocarcinoma/*metabolism , Cyclins/*metabolism , G1 Phase/*radiation effects , Prostatic Hyperplasia/*metabolism , Prostatic Neoplasms/*metabolism , S Phase/*radiation effects , Tumor Suppressor Protein p53/*metabolism, Adenocarcinoma/genetics ; Adenocarcinoma/pathology ; Cell Cycle/radiation effects ; Cyclin-Dependent Kinase Inhibitor p21 ; Epithelium/metabolism ; Epithelium/radiation effects ; Humans ; Male ; Phosphorylation ; Prostatic Hyperplasia/pathology ; Prostatic Neoplasms/genetics ; Prostatic Neoplasms/pathology ; Protein Kinases/metabolism ; Tumor Cells, Cultured ; Tumor Suppressor Protein p53/genetics