المؤلفون: Vétillard A; Paul Papin ICO Cancer Center, INSERM U892, CNRS 6299, Angers University, Angers, France., Jonchère B; Paul Papin ICO Cancer Center, INSERM U892, CNRS 6299, Angers University, Angers, France., Moreau M; Paul Papin ICO Cancer Center, INSERM U892, CNRS 6299, Angers University, Angers, France., Toutain B; Paul Papin ICO Cancer Center, INSERM U892, CNRS 6299, Angers University, Angers, France., Henry C; Paul Papin ICO Cancer Center, INSERM U892, CNRS 6299, Angers University, Angers, France., Fontanel S; Paul Papin ICO Cancer Center, INSERM U892, CNRS 6299, Angers University, Angers, France., Bernard AC; Paul Papin ICO Cancer Center, INSERM U892, CNRS 6299, Angers University, Angers, France., Campone M; Paul Papin ICO Cancer Center, INSERM U892, CNRS 6299, Angers University, Angers, France., Guette C; Paul Papin ICO Cancer Center, INSERM U892, CNRS 6299, Angers University, Angers, France., Coqueret O; Paul Papin ICO Cancer Center, INSERM U892, CNRS 6299, Angers University, Angers, France.

المصدر: Oncotarget [Oncotarget] 2015 Dec 22; Vol. 6 (41), pp. 43342-62.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Impact Journals Country of Publication: United States NLM ID: 101532965 Publication Model: Print Cited Medium: Internet ISSN: 1949-2553 (Electronic) Linking ISSN: 19492553 NLM ISO Abbreviation: Oncotarget Subsets: MEDLINE

مواضيع طبية MeSH: Apoptosis/*physiology , Cellular Senescence/*physiology , Drug Resistance, Neoplasm/*physiology , Proto-Oncogene Proteins c-akt/*antagonists & inhibitors, Animals ; Antineoplastic Agents/pharmacology ; Apoptosis/drug effects ; Blotting, Western ; Camptothecin/analogs & derivatives ; Camptothecin/pharmacology ; Cell Line, Tumor ; Cell Survival/drug effects ; Cellular Senescence/drug effects ; Flow Cytometry ; Fluorescent Antibody Technique ; Gene Knockdown Techniques ; Humans ; Immunoprecipitation ; Irinotecan ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Oxadiazoles/pharmacology ; Xenograft Model Antitumor Assays

المؤلفون: Jonchère B; Paul Papin ICO Cancer Center, INSERM U892, CNRS 6299, Angers University, Angers, France., Vétillard A; Paul Papin ICO Cancer Center, INSERM U892, CNRS 6299, Angers University, Angers, France., Toutain B; Paul Papin ICO Cancer Center, INSERM U892, CNRS 6299, Angers University, Angers, France., Lam D; Paul Papin ICO Cancer Center, INSERM U892, CNRS 6299, Angers University, Angers, France., Bernard AC; Paul Papin ICO Cancer Center, INSERM U892, CNRS 6299, Angers University, Angers, France., Henry C; Paul Papin ICO Cancer Center, INSERM U892, CNRS 6299, Angers University, Angers, France., De Carné Trécesson S; INSERM U892, CNRS 6299, Nantes University, Nantes, France., Gamelin E; Paul Papin ICO Cancer Center, INSERM U892, CNRS 6299, Angers University, Angers, France., Juin P; INSERM U892, CNRS 6299, Nantes University, Nantes, France. Gauducheau ICO Cancer Center, INSERM U892, CNRS 6299, Nantes, France., Guette C; Paul Papin ICO Cancer Center, INSERM U892, CNRS 6299, Angers University, Angers, France., Coqueret O; Paul Papin ICO Cancer Center, INSERM U892, CNRS 6299, Angers University, Angers, France.

المصدر: Oncotarget [Oncotarget] 2015 Jan 01; Vol. 6 (1), pp. 409-26.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Impact Journals Country of Publication: United States NLM ID: 101532965 Publication Model: Print Cited Medium: Internet ISSN: 1949-2553 (Electronic) Linking ISSN: 19492553 NLM ISO Abbreviation: Oncotarget Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents/*pharmacology , Camptothecin/*analogs & derivatives , Cellular Senescence/*drug effects , Colorectal Neoplasms/*pathology , Drug Resistance, Neoplasm/*physiology , Myeloid Cell Leukemia Sequence 1 Protein/*metabolism, Animals ; Apoptosis/drug effects ; Apoptosis/physiology ; Blotting, Western ; Camptothecin/pharmacology ; Cell Line, Tumor ; Cell Transformation, Neoplastic/metabolism ; Flow Cytometry ; Heterografts ; Humans ; Irinotecan ; Male ; Mice ; Mice, Inbred BALB C ; Neoplasm Invasiveness/pathology ; RNA, Small Interfering ; Reverse Transcriptase Polymerase Chain Reaction ; Transfection