المؤلفون: Shen B; Institute of Pharmacology, Shandong First Medical University & Shandong Academy of Medical Sciences, Tai'an 271016, China., Yang L; Institute of Pharmacology, Shandong First Medical University & Shandong Academy of Medical Sciences, Tai'an 271016, China., Jia X; Department of Pharmacy, Liaocheng People's Hospital Affiliated to Shandong First Medical University & Shandong Academy of Medical Sciences, Liao'cheng 252000, China., Kong D; Institute of Pharmacology, Shandong First Medical University & Shandong Academy of Medical Sciences, Tai'an 271016, China., Jing L; Department of Pharmacy, Dongping People's Hospital, Tai'an 271500, China., Gao Y; Institute of Pharmacology, Shandong First Medical University & Shandong Academy of Medical Sciences, Tai'an 271016, China., Gao S; Institute of Pharmacology, Shandong First Medical University & Shandong Academy of Medical Sciences, Tai'an 271016, China., Chen R; Institute of Pharmacology, Shandong First Medical University & Shandong Academy of Medical Sciences, Tai'an 271016, China., Chen F; Institute of Pharmacology, Shandong First Medical University & Shandong Academy of Medical Sciences, Tai'an 271016, China., Zhao C; Institute of Pharmacology, Shandong First Medical University & Shandong Academy of Medical Sciences, Tai'an 271016, China., Li Y; Institute of Pharmacology, Shandong First Medical University & Shandong Academy of Medical Sciences, Tai'an 271016, China., Tan R; Institute of Pharmacology, Shandong First Medical University & Shandong Academy of Medical Sciences, Tai'an 271016, China. Electronic address: rtan@sdfmu.edu.cn., Zhao X; Institute of Pharmacology, Shandong First Medical University & Shandong Academy of Medical Sciences, Tai'an 271016, China. Electronic address: xmzhao@sdfmu.edu.cn.

المصدر: Microvascular research [Microvasc Res] 2024 Jul; Vol. 154, pp. 104681. Date of Electronic Publication: 2024 Mar 16.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Academic Press Country of Publication: United States NLM ID: 0165035 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9319 (Electronic) Linking ISSN: 00262862 NLM ISO Abbreviation: Microvasc Res Subsets: MEDLINE

مواضيع طبية MeSH: Blood-Brain Barrier*/metabolism , Blood-Brain Barrier*/physiopathology , Blood-Brain Barrier*/pathology , Blood Platelets*/metabolism , Endothelial Cells*/metabolism , Signal Transduction* , CD40 Ligand*/metabolism , Baroreflex* , Disease Models, Animal* , Rats, Sprague-Dawley* , Matrix Metalloproteinase 9*/metabolism , Capillary Permeability* , NF-kappa B*/metabolism, Animals ; Male ; Zonula Occludens-1 Protein/metabolism ; Occludin/metabolism ; Cell Line ; Platelet Aggregation ; Arterial Pressure ; Rats

المؤلفون: Zheng ZJ; Department of Pharmacy, Gongan Hospital of Traditional Chinese Medicine, Jingzhou, 434300, China.; Hubei University of Chinese Medicine, Wuhan, 430061, China., Zhu LZ; Department of Pharmacy, The First Affiliated Hospital of Shenzhen University, Shenzhen Second People's Hospital (Shenzhen Institute of Translational Medicine), Shenzhen, 518055, China., Qiu H; Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University, 3002 West Sungang Rd, Shenzhen, 518020, China., Zheng WY; Department of Pharmacy, Gongan Hospital of Traditional Chinese Medicine, Jingzhou, 434300, China.; Hubei University of Chinese Medicine, Wuhan, 430061, China., You PT; Hubei University of Chinese Medicine, Wuhan, 430061, China., Chen SH; Department of Pharmacy, Hubei Provincial Hospital of Traditional Chinese Medicine, Wuhan, 430061, China.; Hubei Shizhen Laboratory, Wuhan, 430061, China., Hu CL; Hubei University of Chinese Medicine, Wuhan, 430061, China., Huang JR; Department of Pharmacy, The First Affiliated Hospital of Shenzhen University, Shenzhen Second People's Hospital (Shenzhen Institute of Translational Medicine), Shenzhen, 518055, China., Zhou YJ; Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University, 3002 West Sungang Rd, Shenzhen, 518020, China. aquazhou@foxmail.com.; Department of Pharmacy, Hubei Provincial Hospital of Traditional Chinese Medicine, Wuhan, 430061, China. aquazhou@foxmail.com.; Hubei Shizhen Laboratory, Wuhan, 430061, China. aquazhou@foxmail.com.

المصدر: Scientific reports [Sci Rep] 2024 Jun 23; Vol. 14 (1), pp. 14438. Date of Electronic Publication: 2024 Jun 23.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

مواضيع طبية MeSH: Blood-Brain Barrier*/metabolism , Blood-Brain Barrier*/drug effects , Pyroptosis*/drug effects , Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha*/metabolism , Ischemic Stroke*/metabolism , Ischemic Stroke*/drug therapy , Ischemic Stroke*/pathology , Endothelial Cells*/metabolism , Endothelial Cells*/drug effects , Benzylisoquinolines*/pharmacology, Animals ; Mice ; Male ; Oxidative Stress/drug effects ; Mitochondria/metabolism ; Mitochondria/drug effects ; Mice, Inbred C57BL ; Disease Models, Animal ; Neuroprotective Agents/pharmacology

المؤلفون: Berve K; Theodor Kocher Institute, University of Bern, Bern, Switzerland., Michel J; Theodor Kocher Institute, University of Bern, Bern, Switzerland., Tietz S; Theodor Kocher Institute, University of Bern, Bern, Switzerland., Blatti C; Theodor Kocher Institute, University of Bern, Bern, Switzerland., Ivan D; Theodor Kocher Institute, University of Bern, Bern, Switzerland., Enzmann G; Theodor Kocher Institute, University of Bern, Bern, Switzerland., Lyck R; Theodor Kocher Institute, University of Bern, Bern, Switzerland., Deutsch U; Theodor Kocher Institute, University of Bern, Bern, Switzerland., Locatelli G; Theodor Kocher Institute, University of Bern, Bern, Switzerland., Engelhardt B; Theodor Kocher Institute, University of Bern, Bern, Switzerland.

المصدر: European journal of immunology [Eur J Immunol] 2024 Jun; Vol. 54 (6), pp. e2350761. Date of Electronic Publication: 2024 Apr 02.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 1273201 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-4141 (Electronic) Linking ISSN: 00142980 NLM ISO Abbreviation: Eur J Immunol Subsets: MEDLINE

مواضيع طبية MeSH: Encephalomyelitis, Autoimmune, Experimental*/immunology , Blood-Brain Barrier*/metabolism , Blood-Brain Barrier*/immunology , Blood-Brain Barrier*/pathology , Mice, Knockout* , Macrophages*/immunology , Macrophages*/metabolism , Endothelial Cells*/metabolism , Endothelial Cells*/immunology , Mice, Inbred C57BL*, Animals ; Mice ; Spinal Cord/pathology ; Spinal Cord/immunology ; Spinal Cord/metabolism ; CD4-Positive T-Lymphocytes/immunology ; Receptors, Cell Surface/genetics ; Receptors, Cell Surface/metabolism ; Multiple Sclerosis/immunology ; Multiple Sclerosis/pathology ; Cell Adhesion Molecules/genetics ; Cell Adhesion Molecules/metabolism ; Disease Models, Animal

المؤلفون: Li C; Shandong Academy of Occupational Health and Occupational Medicine, Shandong First Medical University & Shandong Academy of Medical Sciences, Ji'nan, Shandong, 250062, China., Chen X; Shandong Academy of Occupational Health and Occupational Medicine, Shandong First Medical University & Shandong Academy of Medical Sciences, Ji'nan, Shandong, 250062, China., Du Z; Shandong Academy of Occupational Health and Occupational Medicine, Shandong First Medical University & Shandong Academy of Medical Sciences, Ji'nan, Shandong, 250062, China., Geng X; Shandong Academy of Occupational Health and Occupational Medicine, Shandong First Medical University & Shandong Academy of Medical Sciences, Ji'nan, Shandong, 250062, China., Li M; Shandong Academy of Occupational Health and Occupational Medicine, Shandong First Medical University & Shandong Academy of Medical Sciences, Ji'nan, Shandong, 250062, China., Yang X; Shandong Academy of Occupational Health and Occupational Medicine, Shandong First Medical University & Shandong Academy of Medical Sciences, Ji'nan, Shandong, 250062, China., Bo C; Shandong Academy of Occupational Health and Occupational Medicine, Shandong First Medical University & Shandong Academy of Medical Sciences, Ji'nan, Shandong, 250062, China., Jia Q; Shandong Academy of Occupational Health and Occupational Medicine, Shandong First Medical University & Shandong Academy of Medical Sciences, Ji'nan, Shandong, 250062, China. Electronic address: jiaqiang@sdfmu.edu.cn., Yu G; Neck-Shoulder and Lumbocrural Pain Hospital of Shandong First Medical University, Shandong First Medical University & Shandong Academy of Medical Sciences, Ji'nan, Shandong, 250062, China; Shandong Mental Health Center, Ji'nan, Shandong, 250014, China. Electronic address: yugongchang@sdfmu.edu.cn., Shi L; Neck-Shoulder and Lumbocrural Pain Hospital of Shandong First Medical University, Shandong First Medical University & Shandong Academy of Medical Sciences, Ji'nan, Shandong, 250062, China. Electronic address: shiliang@sdfmu.edu.cn.

المصدر: Environmental research [Environ Res] 2024 Jun 01; Vol. 250, pp. 118506. Date of Electronic Publication: 2024 Feb 20.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0147621 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0953 (Electronic) Linking ISSN: 00139351 NLM ISO Abbreviation: Environ Res Subsets: MEDLINE

مواضيع طبية MeSH: Blood-Brain Barrier*/drug effects , Blood-Brain Barrier*/metabolism , Ferroptosis*/drug effects , Polystyrenes*/toxicity , Endothelial Cells*/drug effects , Endothelial Cells*/metabolism, Animals ; Mice ; Brain/drug effects ; Brain/metabolism ; Brain/blood supply ; Nanoparticles/toxicity ; Male

المؤلفون: Milewski K; Department of Neurotoxicology, Mossakowski Medical Research Institute, Polish Academy of Sciences, Pawińskiego St. 5, 02-106, Warsaw, Poland. kmilewski@imdik.pan.pl., Orzeł-Gajowik K; Department of Neurotoxicology, Mossakowski Medical Research Institute, Polish Academy of Sciences, Pawińskiego St. 5, 02-106, Warsaw, Poland., Zielińska M; Department of Neurotoxicology, Mossakowski Medical Research Institute, Polish Academy of Sciences, Pawińskiego St. 5, 02-106, Warsaw, Poland. mzielinska@imdik.pan.pl.

المصدر: Neurochemical research [Neurochem Res] 2024 Jun; Vol. 49 (6), pp. 1489-1504. Date of Electronic Publication: 2022 Aug 02.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 7613461 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-6903 (Electronic) Linking ISSN: 03643190 NLM ISO Abbreviation: Neurochem Res Subsets: MEDLINE

مواضيع طبية MeSH: Hepatic Encephalopathy*/metabolism , Hepatic Encephalopathy*/pathology , Blood-Brain Barrier*/metabolism , Blood-Brain Barrier*/pathology , Endothelial Cells*/metabolism , Endothelial Cells*/pathology , Mitochondria*/metabolism, Animals ; Rats ; Brain/metabolism ; Brain/pathology ; Mitochondrial Dynamics/physiology

المؤلفون: Zhang H; Department of Neurology, Zhengzhou University People's Hospital, Henan Provincial People's Hospital, Zhengzhou, Henan 450003, China., Shang J; Department of Neurology, Zhengzhou University People's Hospital, Henan Provincial People's Hospital, Zhengzhou, Henan 450003, China., Li W; Department of Neurology, Zhengzhou University People's Hospital, Henan Provincial People's Hospital, Zhengzhou, Henan 450003, China., Gao D; Department of Neurology, Renmin Hospital of Wuhan University, Wuhan, Hubei 430072, China., Zhang J; Department of Neurology, Zhengzhou University People's Hospital, Henan Provincial People's Hospital, Zhengzhou, Henan 450003, China.

المصدر: ACS chemical neuroscience [ACS Chem Neurosci] 2024 May 15; Vol. 15 (10), pp. 2028-2041. Date of Electronic Publication: 2024 May 06.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101525337 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1948-7193 (Electronic) Linking ISSN: 19487193 NLM ISO Abbreviation: ACS Chem Neurosci Subsets: MEDLINE

مواضيع طبية MeSH: Vascular Cell Adhesion Molecule-1*/metabolism , Blood-Brain Barrier*/metabolism , Blood-Brain Barrier*/drug effects , Blood-Brain Barrier*/pathology , Endothelial Cells*/metabolism , Endothelial Cells*/drug effects, Animals ; Male ; Brain/metabolism ; Brain/pathology ; Dementia, Vascular/metabolism ; Dementia, Vascular/pathology ; Humans ; Brain Ischemia/metabolism ; Brain Ischemia/pathology ; Mice

المؤلفون: Svane N; Department of Pharmacy, University of Copenhagen, Copenhagen, Denmark., Pedersen ABV; Department of Pharmacy, University of Copenhagen, Copenhagen, Denmark., Rodenberg A; Department of Pharmacy, University of Copenhagen, Copenhagen, Denmark., Ozgür B; Department of Pharmacy, University of Copenhagen, Copenhagen, Denmark.; Biotherapeutic Discovery, H. Lundbeck A/S, Valby, Denmark., Saaby L; Department of Pharmacy, University of Copenhagen, Copenhagen, Denmark.; Bioneer: FARMA, Bioneer A/S, Copenhagen, Denmark., Bundgaard C; Translational DMPK, H. Lundbeck A/S, Valby, Denmark., Kristensen M; Department of Pharmacy, University of Copenhagen, Copenhagen, Denmark., Tfelt-Hansen P; Danish Headache Center, Department of Neurology, Rigshospitalet-Glostrup, University of Copenhagen, Glostrup, Denmark., Brodin B; Department of Pharmacy, University of Copenhagen, Copenhagen, Denmark. birger.brodin@sund.ku.dk.

المصدر: Fluids and barriers of the CNS [Fluids Barriers CNS] 2024 May 06; Vol. 21 (1), pp. 39. Date of Electronic Publication: 2024 May 06.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Biomed Central Country of Publication: England NLM ID: 101553157 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-8118 (Electronic) Linking ISSN: 20458118 NLM ISO Abbreviation: Fluids Barriers CNS Subsets: MEDLINE

مواضيع طبية MeSH: Tryptamines*/pharmacology , Tryptamines*/metabolism , Tryptamines*/pharmacokinetics , Endothelial Cells*/metabolism , Endothelial Cells*/drug effects , Mice, Knockout* , Blood-Brain Barrier*/metabolism , Blood-Brain Barrier*/drug effects , Brain*/metabolism , Pyrrolidines*, Animals ; Humans ; Cell Line ; Mice ; Mice, Inbred C57BL ; Biological Transport/physiology ; ATP Binding Cassette Transporter, Subfamily B, Member 1/metabolism ; Male ; Antiporters/metabolism ; Pyrilamine/metabolism ; Pyrilamine/pharmacology ; ATP Binding Cassette Transporter, Subfamily B/metabolism

المؤلفون: Carey A; Department of Neural Sciences, Alzheimer's Center at Temple, Temple University Lewis Katz School of Medicine, Philadelphia, Pennsylvania, USA., Parodi-Rullan R; Department of Neural Sciences, Alzheimer's Center at Temple, Temple University Lewis Katz School of Medicine, Philadelphia, Pennsylvania, USA., Vazquez-Torres R; Department of Neural Sciences, Alzheimer's Center at Temple, Temple University Lewis Katz School of Medicine, Philadelphia, Pennsylvania, USA., Canepa E; Department of Neural Sciences, Alzheimer's Center at Temple, Temple University Lewis Katz School of Medicine, Philadelphia, Pennsylvania, USA., Fossati S; Department of Neural Sciences, Alzheimer's Center at Temple, Temple University Lewis Katz School of Medicine, Philadelphia, Pennsylvania, USA.

المصدر: Aging cell [Aging Cell] 2024 May; Vol. 23 (5), pp. e14106. Date of Electronic Publication: 2024 Feb 15.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101130839 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1474-9726 (Electronic) Linking ISSN: 14749718 NLM ISO Abbreviation: Aging Cell Subsets: MEDLINE

مواضيع طبية MeSH: Blood-Brain Barrier*/metabolism , Blood-Brain Barrier*/pathology , Apoptosis* , Amyloid beta-Peptides*/metabolism , Homocysteine*/pharmacology , Homocysteine*/metabolism , Endothelial Cells*/metabolism, Humans ; Receptors, TNF-Related Apoptosis-Inducing Ligand/metabolism ; Receptors, TNF-Related Apoptosis-Inducing Ligand/genetics ; Alzheimer Disease/metabolism ; Alzheimer Disease/pathology ; Neovascularization, Pathologic/metabolism ; Hyperhomocysteinemia/metabolism ; Hyperhomocysteinemia/complications

المؤلفون: Ohbuchi M; Applied Research & Operations, Astellas Pharma Inc., Tsukuba 305-8585, Ibaraki, Japan., Shibuta M; Applied Research & Operations, Astellas Pharma Inc., Tsukuba 305-8585, Ibaraki, Japan., Tetsuka K; Applied Research & Operations, Astellas Pharma Inc., Tsukuba 305-8585, Ibaraki, Japan., Sasaki-Iwaoka H; Applied Research & Operations, Astellas Pharma Inc., Tsukuba 305-8585, Ibaraki, Japan., Oishi M; Applied Research & Operations, Astellas Pharma Inc., Tsukuba 305-8585, Ibaraki, Japan., Shimizu F; Department of Neurology and Clinical Neuroscience, Graduate School of Medicine, Yamaguchi University, Ube 755-8505, Yamaguchi, Japan., Nagasaka Y; Applied Research & Operations, Astellas Pharma Inc., Tsukuba 305-8585, Ibaraki, Japan.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2024 Jun 12; Vol. 25 (12). Date of Electronic Publication: 2024 Jun 12.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Blood-Brain Barrier*/metabolism , Blood-Brain Barrier*/drug effects , Cell Movement*/drug effects , Lab-On-A-Chip Devices* , Endothelial Cells*/metabolism , Endothelial Cells*/drug effects, Humans ; Drug Discovery/methods ; Coculture Techniques ; Pericytes/metabolism ; Pericytes/drug effects ; Claudin-5/metabolism ; Astrocytes/metabolism ; Astrocytes/drug effects ; Chemokine CXCL12/metabolism ; T-Lymphocytes/immunology ; T-Lymphocytes/metabolism ; T-Lymphocytes/drug effects

المؤلفون: Ma X; Program in Cellular and Molecular Medicine, Boston Children's Hospital, and Department of Pediatrics, Harvard Medical School, Boston, MA 02115, USA. Electronic address: xiyu.ma@childrens.harvard.edu., Lieberman J; Program in Cellular and Molecular Medicine, Boston Children's Hospital, and Department of Pediatrics, Harvard Medical School, Boston, MA 02115, USA. Electronic address: judy.lieberman@childrens.harvard.edu.

المصدر: Immunity [Immunity] 2024 Jun 11; Vol. 57 (6), pp. 1192-1194.

نوع المنشور: Journal Article; Comment

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 9432918 Publication Model: Print Cited Medium: Internet ISSN: 1097-4180 (Electronic) Linking ISSN: 10747613 NLM ISO Abbreviation: Immunity Subsets: MEDLINE

مواضيع طبية MeSH: Blood-Brain Barrier*/metabolism , Blood-Brain Barrier*/immunology , Endothelial Cells*/metabolism , Endothelial Cells*/immunology , Lipopolysaccharides*/immunology, Animals ; Humans ; Caspases/metabolism ; Pyroptosis ; Intracellular Signaling Peptides and Proteins/metabolism ; Phosphate-Binding Proteins/metabolism ; Mice