المؤلفون: Ringuette D; Department of Physiology, Faculty of Medicine, University of Toronto, 1 King's College Circle, Toronto, Ontario M5S 1A8, Canada; Division of Genetics and Development, Krembil Research Institute, 60 Leonard Ave., Toronto, Ontario M5T 2S8, Canada; Krembil Neuroscience, Krembil Research Institute, 60 Leonard Ave., Toronto, Ontario M5T 2S8, Canada. Electronic address: dene.ringuette@mail.utoronto.ca., EbrahimAmini A; Krembil Neuroscience, Krembil Research Institute, 60 Leonard Ave., Toronto, Ontario M5T 2S8, Canada; The Institute Biomedical Engineering, University of Toronto, 164 College St., Toronto, Ontario M5S 3G9, Canada., Sangphosuk W; Krembil Neuroscience, Krembil Research Institute, 60 Leonard Ave., Toronto, Ontario M5T 2S8, Canada., Aquilino MS; The Institute Biomedical Engineering, University of Toronto, 164 College St., Toronto, Ontario M5S 3G9, Canada., Carroll G; The Institute Biomedical Engineering, University of Toronto, 164 College St., Toronto, Ontario M5S 3G9, Canada., Ashley M; Krembil Neuroscience, Krembil Research Institute, 60 Leonard Ave., Toronto, Ontario M5T 2S8, Canada., Bazzigaluppi P; Sunnybrook Health Sciences Center, 2075 Bayview Ave., Toronto, Ontario M4N 3M5, Canada., Dufour S; The Institute Biomedical Engineering, University of Toronto, 164 College St., Toronto, Ontario M5S 3G9, Canada., Droguerre M; Theranexus, 60 Ave. Rockefeller, 69008, Lyon, France., Stefanovic B; Department of Medical Biophysics, University of Toronto, 610 University Ave., Toronto, Ontario M5G 2M9, Canada; Sunnybrook Health Sciences Center, 2075 Bayview Ave., Toronto, Ontario M4N 3M5, Canada., Levi O; The Institute Biomedical Engineering, University of Toronto, 164 College St., Toronto, Ontario M5S 3G9, Canada; The Edward S. Rogers Sr. Department of Electrical and Computer Engineering, University of Toronto, 10 King's College Rd., Toronto, Ontario M5S 3G4, Canada., Charveriat M; Theranexus, 60 Ave. Rockefeller, 69008, Lyon, France., Monnier PP; Department of Physiology, Faculty of Medicine, University of Toronto, 1 King's College Circle, Toronto, Ontario M5S 1A8, Canada; Division of Genetics and Development, Krembil Research Institute, 60 Leonard Ave., Toronto, Ontario M5T 2S8, Canada; Department of Ophthalmology & Vision Science, Faculty of Medicine, University of Toronto, 340 College St., Toronto, Ontario M5T 3A9, Canada., Carlen PL; Department of Physiology, Faculty of Medicine, University of Toronto, 1 King's College Circle, Toronto, Ontario M5S 1A8, Canada; Division of Genetics and Development, Krembil Research Institute, 60 Leonard Ave., Toronto, Ontario M5T 2S8, Canada; Krembil Neuroscience, Krembil Research Institute, 60 Leonard Ave., Toronto, Ontario M5T 2S8, Canada; The Institute Biomedical Engineering, University of Toronto, 164 College St., Toronto, Ontario M5S 3G9, Canada.

المصدر: Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics [Neurotherapeutics] 2024 Jan; Vol. 21 (1), pp. e00298. Date of Electronic Publication: 2023 Dec 19.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society for Experimental NeuroTherapeutics Country of Publication: United States NLM ID: 101290381 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-7479 (Electronic) Linking ISSN: 18787479 NLM ISO Abbreviation: Neurotherapeutics Subsets: MEDLINE

مواضيع طبية MeSH: Cortical Spreading Depression* , Epilepsy* , Stroke*, Humans ; Potassium/pharmacology ; Multimodal Imaging

المؤلفون: Santos AC; Krembil Research Institute, University Health Network, Toronto, ON M5S 0T8, Canada.; Institute of Biomedical Engineering, University of Toronto, Toronto, ON M5S 1A1, Canada., Nader G; Krembil Research Institute, University Health Network, Toronto, ON M5S 0T8, Canada., El Soufi El Sabbagh D; Krembil Research Institute, University Health Network, Toronto, ON M5S 0T8, Canada.; Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON M5S 1A1, Canada., Urban K; Avicanna Inc., Toronto, ON M5G 1V2, Canada., Attisano L; Department of Biochemistry, University of Toronto, Toronto, ON M5S 1A1, Canada.; Donnelly Centre, University of Toronto, Toronto, ON M5S 1A1, Canada., Carlen PL; Krembil Research Institute, University Health Network, Toronto, ON M5S 0T8, Canada.; Institute of Biomedical Engineering, University of Toronto, Toronto, ON M5S 1A1, Canada.

المصدر: Cells [Cells] 2023 Jul 27; Vol. 12 (15). Date of Electronic Publication: 2023 Jul 27.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409 (Electronic) Linking ISSN: 20734409 NLM ISO Abbreviation: Cells Subsets: MEDLINE

مواضيع طبية MeSH: Glucose*/metabolism , Epilepsy*/drug therapy , Epilepsy*/metabolism, Humans ; Solute Carrier Family 12, Member 2/metabolism ; Brain/metabolism ; Organoids/metabolism

المؤلفون: Breton VL; Department of Physiology, Faculty of Medicine, University of Toronto, Toronto, Ontario M5S 1A8, Canada; Krembil Research Institute, Division of Fundamental Neurobiology, Toronto Western Hospital, Toronto, Ontario M5T 0S8, Canada. Electronic address: vanessa.breton@mail.utoronto.ca., Aquilino MS; Krembil Research Institute, Division of Fundamental Neurobiology, Toronto Western Hospital, Toronto, Ontario M5T 0S8, Canada; Institute of Biomedical Engineering, University of Toronto, Toronto, Ontario M5S 3G9, Canada. Electronic address: mark.aquilino@mail.utoronto.ca., Repudi S; The Concern Foundation Laboratories, The Lautenberg Center for Immunology and Cancer Research, Immunology and Cancer Research-IMRIC, Hebrew University-Hadassah Medical School, Jerusalem, Israel., Saleem A; Krembil Research Institute, Division of Fundamental Neurobiology, Toronto Western Hospital, Toronto, Ontario M5T 0S8, Canada; Institute of Biomedical Engineering, University of Toronto, Toronto, Ontario M5S 3G9, Canada., Mylvaganam S; Krembil Research Institute, Division of Fundamental Neurobiology, Toronto Western Hospital, Toronto, Ontario M5T 0S8, Canada., Abu-Swai S; The Concern Foundation Laboratories, The Lautenberg Center for Immunology and Cancer Research, Immunology and Cancer Research-IMRIC, Hebrew University-Hadassah Medical School, Jerusalem, Israel., Bardakjian BL; Institute of Biomedical Engineering, University of Toronto, Toronto, Ontario M5S 3G9, Canada; Edward S. Rogers Sr. Department of Electrical and Computer Engineering, University of Toronto, Toronto, Ontario M5S 3G4, Canada., Aqeilan RI; The Concern Foundation Laboratories, The Lautenberg Center for Immunology and Cancer Research, Immunology and Cancer Research-IMRIC, Hebrew University-Hadassah Medical School, Jerusalem, Israel., Carlen PL; Department of Physiology, Faculty of Medicine, University of Toronto, Toronto, Ontario M5S 1A8, Canada; Krembil Research Institute, Division of Fundamental Neurobiology, Toronto Western Hospital, Toronto, Ontario M5T 0S8, Canada; Institute of Biomedical Engineering, University of Toronto, Toronto, Ontario M5S 3G9, Canada; Department of Medicine (Neurology), University Health Network, Toronto, Ontario M5G 2C4, Canada.

المصدر: Neurobiology of disease [Neurobiol Dis] 2021 Dec; Vol. 160, pp. 105529. Date of Electronic Publication: 2021 Oct 09.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Academic Press Country of Publication: United States NLM ID: 9500169 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-953X (Electronic) Linking ISSN: 09699961 NLM ISO Abbreviation: Neurobiol Dis Subsets: MEDLINE

مواضيع طبية MeSH: Action Potentials/*physiology , Epilepsy/*physiopathology , Neocortex/*physiopathology , Pyramidal Cells/*physiology , WW Domain-Containing Oxidoreductase/*genetics, Animals ; Epilepsy/genetics ; Mice ; Mice, Knockout

المؤلفون: Repudi S; The Concern Foundation Laboratories, The Lautenberg Center for Immunology and Cancer Research, Immunology and Cancer Research-IMRIC, Hebrew University-Hadassah Medical School, Jerusalem, Israel., Steinberg DJ; The Concern Foundation Laboratories, The Lautenberg Center for Immunology and Cancer Research, Immunology and Cancer Research-IMRIC, Hebrew University-Hadassah Medical School, Jerusalem, Israel., Elazar N; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 76100, Israel., Breton VL; Krembil Research Institute, University Health Network, Toronto, Canada., Aquilino MS; Krembil Research Institute, University Health Network, Toronto, Canada., Saleem A; Krembil Research Institute, University Health Network, Toronto, Canada., Abu-Swai S; The Concern Foundation Laboratories, The Lautenberg Center for Immunology and Cancer Research, Immunology and Cancer Research-IMRIC, Hebrew University-Hadassah Medical School, Jerusalem, Israel., Vainshtein A; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 76100, Israel., Eshed-Eisenbach Y; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 76100, Israel., Vijayaragavan B; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 76100, Israel., Behar O; Department of Developmental Biology and Cancer Research-IMRIC, Hebrew University-Hadassah Medical School, Jerusalem, Israel., Hanna JJ; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel., Peles E; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 76100, Israel., Carlen PL; Krembil Research Institute, University Health Network, Toronto, Canada., Aqeilan RI; The Concern Foundation Laboratories, The Lautenberg Center for Immunology and Cancer Research, Immunology and Cancer Research-IMRIC, Hebrew University-Hadassah Medical School, Jerusalem, Israel.

المصدر: Brain : a journal of neurology [Brain] 2021 Nov 29; Vol. 144 (10), pp. 3061-3077.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 0372537 Publication Model: Print Cited Medium: Internet ISSN: 1460-2156 (Electronic) Linking ISSN: 00068950 NLM ISO Abbreviation: Brain Subsets: MEDLINE

مواضيع طبية MeSH: Gene Deletion*, Epilepsy/*genetics , Myelin Sheath/*genetics , Neurons/*physiology , WW Domain-Containing Oxidoreductase/*deficiency , WW Domain-Containing Oxidoreductase/*genetics, Animals ; Brain/pathology ; Coculture Techniques ; Epilepsy/pathology ; Humans ; Mice ; Mice, Knockout ; Mice, Transgenic ; Myelin Sheath/pathology ; Neurons/pathology ; Organoids ; WW Domain-Containing Oxidoreductase/antagonists & inhibitors

المؤلفون: Breton VL; Department of Physiology, Faculty of Medicine, University of Toronto, Toronto, Ontario M5S 1A8, Canada; Krembil Research Institute, Division of Fundamental Neurobiology, Toronto Western Hospital, Toronto, Ontario M5T 0S8, Canada. Electronic address: Vanessa.breton@mail.utoronto.ca., Dufour S; Krembil Research Institute, Division of Fundamental Neurobiology, Toronto Western Hospital, Toronto, Ontario M5T 0S8, Canada; National Optics Institute, Biophotonics, Quebec, Canada G1P 4S4., Chinvarun Y; Comprehensive Epilepsy Program and Neurology Unit, Phramongkutklao Hospital, Bangkok, Thailand., Del Campo JM; Department of Medicine (Neurology), University Health Network, Toronto, Ontario M5G 2C4, Canada., Bardakjian BL; Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario M5S 3G9, Canada; Edward S. Rogers Sr. Department of Electrical and Computer Engineering, University of Toronto, Toronto, Ontario M5S 3G4, Canada., Carlen PL; Department of Physiology, Faculty of Medicine, University of Toronto, Toronto, Ontario M5S 1A8, Canada; Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario M5S 3G9, Canada; Krembil Research Institute, Division of Fundamental Neurobiology, Toronto Western Hospital, Toronto, Ontario M5T 0S8, Canada; Department of Medicine (Neurology), University Health Network, Toronto, Ontario M5G 2C4, Canada.

المصدر: Neurobiology of disease [Neurobiol Dis] 2020 Dec; Vol. 146, pp. 105124. Date of Electronic Publication: 2020 Sep 30.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Academic Press Country of Publication: United States NLM ID: 9500169 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-953X (Electronic) Linking ISSN: 09699961 NLM ISO Abbreviation: Neurobiol Dis Subsets: MEDLINE

مواضيع طبية MeSH: Epilepsy/*metabolism , Excitatory Postsynaptic Potentials/*physiology , Glutamic Acid/*metabolism , Seizures/*metabolism , Synapses/*metabolism, Adult ; Animals ; Epilepsy/physiopathology ; Female ; Humans ; Male ; Mice, Inbred C57BL ; Neocortex/physiopathology ; Patch-Clamp Techniques/methods ; Seizures/physiopathology ; Synaptic Transmission/physiology ; Young Adult

المؤلفون: Aquilino MS; IBME, University of Toronto, 164 College Street, Rosebrugh Building, Room 407, Toronto, ON M5S 3G9, Canada.; Krembil Research Institute, University Health Network, 135 Nassau Street, Toronto, ON M5T 1M8, Canada., Whyte-Fagundes P; Department of Biology, York University, 4700 Keele Street, Toronto, ON M5S 3G9, Canada., Lukewich MK; Krembil Research Institute, University Health Network, 135 Nassau Street, Toronto, ON M5T 1M8, Canada., Zhang L; Krembil Research Institute, University Health Network, 135 Nassau Street, Toronto, ON M5T 1M8, Canada., Bardakjian BL; IBME, University of Toronto, 164 College Street, Rosebrugh Building, Room 407, Toronto, ON M5S 3G9, Canada., Zoidl GR; Department of Biology, York University, 4700 Keele Street, Toronto, ON M5S 3G9, Canada., Carlen PL; IBME, University of Toronto, 164 College Street, Rosebrugh Building, Room 407, Toronto, ON M5S 3G9, Canada.; Krembil Research Institute, University Health Network, 135 Nassau Street, Toronto, ON M5T 1M8, Canada.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2020 Oct 12; Vol. 21 (20). Date of Electronic Publication: 2020 Oct 12.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Phenotype*, Connexins/*deficiency , Epilepsy/*etiology , Epilepsy/*physiopathology , Nerve Tissue Proteins/*deficiency, Animals ; Brain Waves ; CA3 Region, Hippocampal/metabolism ; CA3 Region, Hippocampal/physiopathology ; Disease Models, Animal ; Electric Stimulation ; Female ; Genetic Association Studies ; Genetic Predisposition to Disease ; Kindling, Neurologic ; Mice ; Mice, Knockout ; Seizures

المؤلفون: Kalitzin S; Stichting Epilepsie Instellingen Nederland (SEIN) Heemstede and Zwolle, The Netherlands., Petkov G; Stichting Epilepsie Instellingen Nederland (SEIN) Heemstede and Zwolle, The Netherlands., Suffczynski P; Department of Biomedical Physics, Institute of Experimental Physics, University of Warsaw, 5 Pasteur St, Warsaw 02-093, Poland., Grigorovsky V; Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto M5S 3G9, Canada., Bardakjian BL; Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto M5S 3G9, Canada., Lopes da Silva F; Center of Neurosciences, Swammerdam Institute of Life Sciences, University of Amsterdam, P.O. Box 94215 1090, GE, The Netherlands., Carlen PL; Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto M5S 3G9, Canada; Krembil Research Institute, UHN, and Depts. of Medicine (Neurology), Physiology & IBBME, University of Toronto, Canada. Electronic address: peter.carlen@uhnresearch.ca.

المصدر: Neurobiology of disease [Neurobiol Dis] 2019 Oct; Vol. 130, pp. 104488. Date of Electronic Publication: 2019 Jun 07.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: Academic Press Country of Publication: United States NLM ID: 9500169 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-953X (Electronic) Linking ISSN: 09699961 NLM ISO Abbreviation: Neurobiol Dis Subsets: MEDLINE

مواضيع طبية MeSH: Models, Neurological*, Brain/*physiopathology , Epilepsy/*physiopathology , Nerve Net/*physiology, Animals ; Humans

المؤلفون: Aquilino MS; IBBME, University of Toronto, Rosebrugh Building, Room 407, 164 College St, Toronto, ON, M5S 3G9, Canada; Krembil Research Institute, University Health Network, 135 Nassau St, Toronto, ON, M5T 1M8, Canada. Electronic address: mark.aquilino@mail.utoronto.ca., Whyte-Fagundes P; York University, 4700 Keele St, Toronto, ON, M3J 1P3, Canada., Zoidl G; York University, 4700 Keele St, Toronto, ON, M3J 1P3, Canada; Krembil Research Institute, University Health Network, 135 Nassau St, Toronto, ON, M5T 1M8, Canada., Carlen PL; IBBME, University of Toronto, Rosebrugh Building, Room 407, 164 College St, Toronto, ON, M5S 3G9, Canada; Krembil Research Institute, University Health Network, 135 Nassau St, Toronto, ON, M5T 1M8, Canada.

المصدر: Neuroscience letters [Neurosci Lett] 2019 Mar 16; Vol. 695, pp. 71-75. Date of Electronic Publication: 2017 Sep 05.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: Elsevier Scientific Publishers Ireland Country of Publication: Ireland NLM ID: 7600130 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7972 (Electronic) Linking ISSN: 03043940 NLM ISO Abbreviation: Neurosci Lett Subsets: MEDLINE

مواضيع طبية MeSH: Connexins/*metabolism , Epilepsy/*metabolism , Nerve Tissue Proteins/*metabolism, Animals ; Humans ; Neurons/metabolism ; Receptors, Purinergic P2X7/metabolism

المؤلفون: Li C, Jacobs D, Hilton T, Campo MD, Chinvarun Y, Carlen PL, Bardakjian BL

المصدر: IEEE transactions on bio-medical engineering [IEEE Trans Biomed Eng] 2016 Dec; Vol. 63 (12), pp. 2607-2618.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Institute Of Electrical And Electronics Engineers Country of Publication: United States NLM ID: 0012737 Publication Model: Print Cited Medium: Internet ISSN: 1558-2531 (Electronic) Linking ISSN: 00189294 NLM ISO Abbreviation: IEEE Trans Biomed Eng Subsets: MEDLINE

مواضيع طبية MeSH: Brain Mapping/*methods , Electroencephalography/*methods , Epilepsy/*physiopathology , Scalp/*physiology, Adolescent ; Adult ; Brain/physiology ; Brain/physiopathology ; Female ; Humans ; Male ; Middle Aged ; Signal Processing, Computer-Assisted ; Young Adult

المؤلفون: Cotic M, Chinvarun Y, del Campo M, Carlen PL, Bardakjian BL

المصدر: IEEE transactions on bio-medical engineering [IEEE Trans Biomed Eng] 2016 Jan; Vol. 63 (1), pp. 76-85. Date of Electronic Publication: 2014 Dec 30.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Institute Of Electrical And Electronics Engineers Country of Publication: United States NLM ID: 0012737 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1558-2531 (Electronic) Linking ISSN: 00189294 NLM ISO Abbreviation: IEEE Trans Biomed Eng Subsets: MEDLINE

مواضيع طبية MeSH: Signal Processing, Computer-Assisted*, Electroencephalography/*methods , Epilepsy/*physiopathology, Adolescent ; Adult ; Algorithms ; Female ; Humans ; Male ; Middle Aged ; Young Adult