المؤلفون: Rusnak DW; Translational Medicine, GlaxoSmithKline, King of Prussia, PA, USA. david.w.rusnak@gsk.com, Alligood KJ, Mullin RJ, Spehar GM, Arenas-Elliott C, Martin AM, Degenhardt Y, Rudolph SK, Haws TF Jr, Hudson-Curtis BL, Gilmer TM

المصدر: Cell proliferation [Cell Prolif] 2007 Aug; Vol. 40 (4), pp. 580-94.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Published for the Cell Kinetics Society, the European Study Group for Cell Proliferation, and the International Cell Cycle Society by Blackwell Scientific Publications Country of Publication: England NLM ID: 9105195 Publication Model: Print Cited Medium: Print ISSN: 0960-7722 (Print) Linking ISSN: 09607722 NLM ISO Abbreviation: Cell Prolif Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents/*pharmacology , ErbB Receptors/*metabolism , Protein Kinase Inhibitors/*pharmacology , Quinazolines/*pharmacology , Receptor, ErbB-2/*metabolism, Cell Line ; Cell Line, Transformed ; Cell Line, Tumor ; Humans ; Lapatinib ; Models, Statistical

المؤلفون: Rusnak DW; Department of Cancer Biology, GlaxoSmithKline, 5 Moore Drive, Research Triangle Park, NC 27709, USA., Lackey K, Affleck K, Wood ER, Alligood KJ, Rhodes N, Keith BR, Murray DM, Knight WB, Mullin RJ, Gilmer TM

المصدر: Molecular cancer therapeutics [Mol Cancer Ther] 2001 Dec; Vol. 1 (2), pp. 85-94.

نوع المنشور: Comparative Study; Journal Article

بيانات الدورية: Publisher: American Association for Cancer Research, Inc Country of Publication: United States NLM ID: 101132535 Publication Model: Print Cited Medium: Print ISSN: 1535-7163 (Print) Linking ISSN: 15357163 NLM ISO Abbreviation: Mol Cancer Ther Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents/*pharmacology , Cell Division/*drug effects , Enzyme Inhibitors/*pharmacology , ErbB Receptors/*antagonists & inhibitors , Furans/*pharmacology , Neoplasms, Experimental/*drug therapy , Quinazolines/*pharmacology , Receptor, ErbB-2/*antagonists & inhibitors, Animals ; Apoptosis ; Blotting, Western ; Cell Cycle/drug effects ; Epidermal Growth Factor/pharmacology ; ErbB Receptors/metabolism ; Female ; Fibroblasts/drug effects ; Humans ; Infant, Newborn ; Mice ; Mice, Nude ; Mice, SCID ; Neoplasms, Experimental/metabolism ; Neoplasms, Experimental/pathology ; Phosphorylation ; Precipitin Tests ; Receptor, ErbB-2/metabolism ; Signal Transduction/drug effects ; Skin/cytology ; Tumor Cells, Cultured/drug effects ; Tumor Cells, Cultured/metabolism ; Xenograft Model Antitumor Assays

المؤلفون: Rusnak DW; Department of Cancer Biology, GlaxoSmithKline, Research Triangle Park, North Carolina 27709, USA., Affleck K, Cockerill SG, Stubberfield C, Harris R, Page M, Smith KJ, Guntrip SB, Carter MC, Shaw RJ, Jowett A, Stables J, Topley P, Wood ER, Brignola PS, Kadwell SH, Reep BR, Mullin RJ, Alligood KJ, Keith BR, Crosby RM, Murray DM, Knight WB, Gilmer TM, Lackey K

المصدر: Cancer research [Cancer Res] 2001 Oct 01; Vol. 61 (19), pp. 7196-203.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print Cited Medium: Print ISSN: 0008-5472 (Print) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents/*pharmacology , Enzyme Inhibitors/*pharmacology , ErbB Receptors/*antagonists & inhibitors , Quinazolines/*pharmacology , Receptor, ErbB-2/*antagonists & inhibitors, Animals ; Cell Division/drug effects ; Drug Screening Assays, Antitumor ; Female ; Growth Inhibitors/pharmacology ; Humans ; Mice ; Mice, SCID ; Structure-Activity Relationship ; Tumor Cells, Cultured ; Xenograft Model Antitumor Assays

المؤلفون: Luttrell DK; Department of Cell Biology, Glaxo Research Institute, Research Triangle Park, NC 27709., Lee A, Lansing TJ, Crosby RM, Jung KD, Willard D, Luther M, Rodriguez M, Berman J, Gilmer TM

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 1994 Jan 04; Vol. 91 (1), pp. 83-7.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print Cited Medium: Print ISSN: 0027-8424 (Print) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: Breast Neoplasms/*metabolism , ErbB Receptors/*metabolism , Proto-Oncogene Proteins/*metabolism , Proto-Oncogene Proteins pp60(c-src)/*metabolism, Amino Acid Sequence ; Binding, Competitive ; Humans ; In Vitro Techniques ; Molecular Sequence Data ; Phosphopeptides/metabolism ; Protein Binding ; Receptor Protein-Tyrosine Kinases/metabolism ; Receptor, ErbB-2 ; Signal Transduction ; Tumor Cells, Cultured