المؤلفون: Mambetsariev I; Department of Medical Oncology and Therapeutics Research, City of Hope Comprehensive Cancer Center and Beckman Research Institute, 1500 E Duarte Rd, Duarte, CA, 91010-3000, USA., Vora L; Department of Diagnostic Radiology, City of Hope Comprehensive Cancer Center and Beckman Research Institute, Duarte, CA, 91010, USA., Yu KW; Department of Pharmacy Services, City of Hope Comprehensive Cancer Center and Beckman Research Institute, Duarte, CA, 91010, USA., Salgia R; Department of Medical Oncology and Therapeutics Research, City of Hope Comprehensive Cancer Center and Beckman Research Institute, 1500 E Duarte Rd, Duarte, CA, 91010-3000, USA. rsalgia@coh.org.

المصدر: BMC cancer [BMC Cancer] 2018 Mar 21; Vol. 18 (1), pp. 314. Date of Electronic Publication: 2018 Mar 21.

نوع المنشور: Case Reports; Journal Article

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407 (Electronic) Linking ISSN: 14712407 NLM ISO Abbreviation: BMC Cancer Subsets: MEDLINE

مواضيع طبية MeSH: Mutation*, ErbB Receptors/*genetics , Neoplasms/*diagnosis , Neoplasms/*genetics, Acrylamides ; Alleles ; Amino Acid Substitution ; Aniline Compounds ; Antineoplastic Agents/therapeutic use ; Biomarkers, Tumor ; Biopsy ; Carcinoma, Non-Small-Cell Lung/diagnosis ; Carcinoma, Non-Small-Cell Lung/drug therapy ; Carcinoma, Non-Small-Cell Lung/genetics ; Humans ; Liquid Biopsy ; Lung Neoplasms/diagnosis ; Lung Neoplasms/drug therapy ; Lung Neoplasms/genetics ; Magnetic Resonance Angiography ; Male ; Middle Aged ; Neoplasms/drug therapy ; Piperazines/therapeutic use ; Protein Kinase Inhibitors/therapeutic use ; Tomography, X-Ray Computed

المؤلفون: Brand TM; Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, 1111 Highland Avenue, Madison, WI 53705, USA., Iida M; Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, 1111 Highland Avenue, Madison, WI 53705, USA., Corrigan KL; Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, 1111 Highland Avenue, Madison, WI 53705, USA., Braverman CM; Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, 1111 Highland Avenue, Madison, WI 53705, USA., Coan JP; Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, 1111 Highland Avenue, Madison, WI 53705, USA., Flanigan BG; Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, 1111 Highland Avenue, Madison, WI 53705, USA., Stein AP; Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, 1111 Highland Avenue, Madison, WI 53705, USA., Salgia R; Department of Medical Oncology and Therapeutics Research, City of Hope Comprehensive Cancer Center, 1500 East Duarte Road, Duarte, CA 91010, USA., Rolff J; Experimental Pharmacology and Oncology Berlin-Buch GmbH, Robert-Roessle-Str. 10, 13125 Berlin, Germany., Kimple RJ; Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, 1111 Highland Avenue, Madison, WI 53705, USA., Wheeler DL; Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, 1111 Highland Avenue, Madison, WI 53705, USA. dlwheeler@wisc.edu.

المصدر: Science signaling [Sci Signal] 2017 Jan 03; Vol. 10 (460). Date of Electronic Publication: 2017 Jan 03.

نوع المنشور: Journal Article; Retracted Publication

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101465400 Publication Model: Electronic Cited Medium: Internet ISSN: 1937-9145 (Electronic) Linking ISSN: 19450877 NLM ISO Abbreviation: Sci Signal Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Non-Small-Cell Lung/*metabolism , Cell Nucleus/*metabolism , ErbB Receptors/*metabolism , Lung Neoplasms/*metabolism , Proto-Oncogene Proteins/*metabolism , Receptor Protein-Tyrosine Kinases/*metabolism, Active Transport, Cell Nucleus ; Animals ; Antineoplastic Agents/pharmacology ; Carcinoma, Non-Small-Cell Lung/genetics ; Carcinoma, Non-Small-Cell Lung/pathology ; Cell Line, Tumor ; Cetuximab/pharmacology ; Drug Resistance, Neoplasm ; ErbB Receptors/genetics ; Humans ; Immunoblotting ; Lung Neoplasms/genetics ; Lung Neoplasms/pathology ; Mice, Inbred NOD ; Mice, SCID ; Microscopy, Confocal ; Neuregulin-1/genetics ; Neuregulin-1/metabolism ; Proto-Oncogene Proteins/genetics ; RNA Interference ; Receptor Protein-Tyrosine Kinases/genetics ; Transplantation, Heterologous ; src-Family Kinases/genetics ; src-Family Kinases/metabolism ; Axl Receptor Tyrosine Kinase

المؤلفون: Shi P; Department of Respiratory and Critical Care Medicine, First Affiliated Hospital of Medical College of Xi'an Jiaotong University, Xi'an, Shaanxi, China; Department of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, GA, USA., Oh YT; Department of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, GA, USA., Zhang G; Department of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, GA, USA., Yao W; Department of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, GA, USA., Yue P; Department of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, GA, USA., Li Y; Department of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, GA, USA., Kanteti R; Department of Medicine, Section of Hematology/Oncology, University of Chicago, Chicago, IL, USA., Riehm J; Department of Medicine, Section of Hematology/Oncology, University of Chicago, Chicago, IL, USA., Salgia R; Department of Medical Oncology and Therapeutic Research, City of Hope, Duarte, CA, USA., Owonikoko TK; Department of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, GA, USA., Ramalingam SS; Department of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, GA, USA., Chen M; Department of Respiratory and Critical Care Medicine, First Affiliated Hospital of Medical College of Xi'an Jiaotong University, Xi'an, Shaanxi, China. Electronic address: chenmingwei@mail.xjtu.edu.cn., Sun SY; Department of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, GA, USA. Electronic address: ssun@emory.edu.

المصدر: Cancer letters [Cancer Lett] 2016 Oct 01; Vol. 380 (2), pp. 494-504. Date of Electronic Publication: 2016 Jul 19.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Ireland Country of Publication: Ireland NLM ID: 7600053 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7980 (Electronic) Linking ISSN: 03043835 NLM ISO Abbreviation: Cancer Lett Subsets: MEDLINE

مواضيع طبية MeSH: Drug Resistance, Neoplasm*/drug effects , Drug Resistance, Neoplasm*/genetics , Gene Amplification*, Antineoplastic Agents/*pharmacology , Antineoplastic Combined Chemotherapy Protocols/*pharmacology , Carcinoma, Non-Small-Cell Lung/*drug therapy , ErbB Receptors/*antagonists & inhibitors , Lung Neoplasms/*drug therapy , Protein Kinase Inhibitors/*pharmacology , Proto-Oncogene Proteins c-met/*genetics , Proto-Oncogene Proteins c-met/*metabolism, Acrylamides/pharmacology ; Aniline Compounds/pharmacology ; Animals ; Apoptosis/drug effects ; Carcinoma, Non-Small-Cell Lung/enzymology ; Carcinoma, Non-Small-Cell Lung/genetics ; Carcinoma, Non-Small-Cell Lung/pathology ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Crizotinib ; Dose-Response Relationship, Drug ; ErbB Receptors/genetics ; ErbB Receptors/metabolism ; Erlotinib Hydrochloride/pharmacology ; Female ; G1 Phase Cell Cycle Checkpoints/drug effects ; Gene Expression Regulation, Neoplastic ; Humans ; Lung Neoplasms/enzymology ; Lung Neoplasms/genetics ; Lung Neoplasms/pathology ; Mice, Nude ; Molecular Targeted Therapy ; Mutation ; Pyrazoles/pharmacology ; Pyridines/pharmacology ; Pyrimidines/pharmacology ; RNA Interference ; Signal Transduction/drug effects ; Time Factors ; Transfection ; Tumor Burden/drug effects ; Xenograft Model Antitumor Assays

المؤلفون: Iida M; Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin., Bahrar H; Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin. Radboud Department of Radiation Oncology, University Medical Centre Nijmegen, Nijmegen, the Netherlands., Brand TM; Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin., Pearson HE; Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin., Coan JP; Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin., Orbuch RA; Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin., Flanigan BG; Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin., Swick AD; Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin., Prabakaran PJ; Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin., Lantto J; Symphogen A/S, Ballerup, Denmark., Horak ID; Symphogen A/S, Ballerup, Denmark., Kragh M; Symphogen A/S, Ballerup, Denmark., Salgia R; City of Hope, Duarte, California., Kimple RJ; Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin., Wheeler DL; Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin. dlwheeler@wisc.edu.

المصدر: Molecular cancer therapeutics [Mol Cancer Ther] 2016 Sep; Vol. 15 (9), pp. 2175-86. Date of Electronic Publication: 2016 Jul 15.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Association for Cancer Research, Inc Country of Publication: United States NLM ID: 101132535 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-8514 (Electronic) Linking ISSN: 15357163 NLM ISO Abbreviation: Mol Cancer Ther Subsets: MEDLINE

مواضيع طبية MeSH: Drug Resistance, Neoplasm*, Antibodies, Monoclonal/*pharmacology , Antineoplastic Agents/*pharmacology , Cetuximab/*pharmacology , ErbB Receptors/*antagonists & inhibitors, Animals ; Carcinoma, Non-Small-Cell Lung ; Carcinoma, Squamous Cell ; Cell Cycle Checkpoints/drug effects ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Disease Models, Animal ; Female ; Head and Neck Neoplasms ; Humans ; Male ; Mice ; Protein Kinase Inhibitors/pharmacology ; Receptor, ErbB-2/antagonists & inhibitors ; Receptor, ErbB-3/antagonists & inhibitors ; Squamous Cell Carcinoma of Head and Neck ; Tumor Burden ; Xenograft Model Antitumor Assays

المؤلفون: Brand TM; Authors' Affiliations: Departments of Human Oncology and Pathology and Laboratory Medicine, University of Wisconsin School of Medicine and Public Health, Department of Medicine, University of Wisconsin Carbone Cancer Center, Madison, Wisconsin; and Division of Hematology/Oncology, Department of Medicine, University of Chicago, Chicago, Illinois., Iida M, Dunn EF, Luthar N, Kostopoulos KT, Corrigan KL, Wleklinski MJ, Yang D, Wisinski KB, Salgia R, Wheeler DL

المصدر: Molecular cancer therapeutics [Mol Cancer Ther] 2014 May; Vol. 13 (5), pp. 1356-68. Date of Electronic Publication: 2014 Mar 14.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: American Association for Cancer Research, Inc Country of Publication: United States NLM ID: 101132535 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-8514 (Electronic) Linking ISSN: 15357163 NLM ISO Abbreviation: Mol Cancer Ther Subsets: MEDLINE

مواضيع طبية MeSH: Cell Nucleus/*metabolism , ErbB Receptors/*metabolism , Triple Negative Breast Neoplasms/*metabolism, Animals ; Antibodies, Monoclonal, Humanized/pharmacology ; Antineoplastic Agents/pharmacology ; Cell Line, Tumor ; Cell Proliferation ; Cetuximab ; Disease Models, Animal ; Drug Resistance, Neoplasm/genetics ; ErbB Receptors/antagonists & inhibitors ; ErbB Receptors/genetics ; Female ; Gene Expression ; Humans ; Mice ; Protein Transport ; Signal Transduction/drug effects ; Triple Negative Breast Neoplasms/genetics ; Triple Negative Breast Neoplasms/pathology ; Xenograft Model Antitumor Assays ; src-Family Kinases/metabolism

المؤلفون: Traynor AM; Department of Medicine and Carbone Cancer Center, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA., Weigel TL, Oettel KR, Yang DT, Zhang C, Kim K, Salgia R, Iida M, Brand TM, Hoang T, Campbell TC, Hernan HR, Wheeler DL

المصدر: Lung cancer (Amsterdam, Netherlands) [Lung Cancer] 2013 Jul; Vol. 81 (1), pp. 138-41. Date of Electronic Publication: 2013 Apr 28.

نوع المنشور: Journal Article; Observational Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Scientific Publishers Country of Publication: Ireland NLM ID: 8800805 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-8332 (Electronic) Linking ISSN: 01695002 NLM ISO Abbreviation: Lung Cancer Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Non-Small-Cell Lung/*metabolism , Carcinoma, Non-Small-Cell Lung/*mortality , ErbB Receptors/*metabolism , Lung Neoplasms/*metabolism , Lung Neoplasms/*mortality, Adenocarcinoma/metabolism ; Adenocarcinoma/mortality ; Adenocarcinoma/pathology ; Adenocarcinoma/surgery ; Adult ; Aged ; Aged, 80 and over ; Biomarkers, Tumor/metabolism ; Carcinoma, Non-Small-Cell Lung/pathology ; Carcinoma, Non-Small-Cell Lung/surgery ; Carcinoma, Squamous Cell/metabolism ; Carcinoma, Squamous Cell/mortality ; Carcinoma, Squamous Cell/pathology ; Carcinoma, Squamous Cell/surgery ; Cell Nucleus/metabolism ; Disease-Free Survival ; Female ; Humans ; Lung Neoplasms/pathology ; Lung Neoplasms/surgery ; Male ; Middle Aged ; Predictive Value of Tests ; Retrospective Studies

المؤلفون: Pietanza MC; Department of Medicine, Thoracic Oncology Service, Division of Solid Tumor Oncology, Memorial Sloan-Kettering Cancer Center and Weill Medical College of Cornell University, New York, NY, USA. pietanzm@mskcc.org, Gadgeel SM, Dowlati A, Lynch TJ, Salgia R, Rowland KM Jr, Wertheim MS, Price KA, Riely GJ, Azzoli CG, Miller VA, Krug LM, Kris MG, Beumer JH, Tonda M, Mitchell B, Rizvi NA

المصدر: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer [J Thorac Oncol] 2012 May; Vol. 7 (5), pp. 856-65.

نوع المنشور: Clinical Trial, Phase II; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 101274235 Publication Model: Print Cited Medium: Internet ISSN: 1556-1380 (Electronic) Linking ISSN: 15560864 NLM ISO Abbreviation: J Thorac Oncol Subsets: MEDLINE

مواضيع طبية MeSH: Adenocarcinoma/*drug therapy , Azabicyclo Compounds/*therapeutic use , Carcinoma, Non-Small-Cell Lung/*drug therapy , ErbB Receptors/*antagonists & inhibitors , Lung Neoplasms/*drug therapy , Quinazolines/*therapeutic use , Receptor, ErbB-2/*antagonists & inhibitors, Adenocarcinoma/genetics ; Adenocarcinoma/mortality ; Adult ; Aged ; Aged, 80 and over ; Azabicyclo Compounds/pharmacokinetics ; Carcinoma, Non-Small-Cell Lung/genetics ; Carcinoma, Non-Small-Cell Lung/mortality ; Cohort Studies ; ErbB Receptors/genetics ; Female ; Humans ; Lung Neoplasms/genetics ; Lung Neoplasms/mortality ; Male ; Middle Aged ; Mutation/genetics ; Neoplasm Staging ; Prognosis ; Proto-Oncogene Proteins/genetics ; Proto-Oncogene Proteins p21(ras) ; Quinazolines/pharmacokinetics ; Survival Rate ; Tissue Distribution ; ras Proteins/genetics

المؤلفون: Liu W; Department of Medicine; Comprehensive Cancer Center, and Committee on Clinical Pharmacology and Pharmacogenomics, The University of Chicago, Chicago, Illinois, USA., He L, Ramírez J, Krishnaswamy S, Kanteti R, Wang YC, Salgia R, Ratain MJ

المصدر: Cancer research [Cancer Res] 2011 Apr 01; Vol. 71 (7), pp. 2423-7. Date of Electronic Publication: 2011 Feb 03.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Germ-Line Mutation*, Asian People/*genetics , Carcinoma, Non-Small-Cell Lung/*genetics , ErbB Receptors/*genetics , Lung Neoplasms/*genetics, Allelic Imbalance ; Carcinoma, Non-Small-Cell Lung/enzymology ; Carcinoma, Non-Small-Cell Lung/ethnology ; Case-Control Studies ; Exons ; Gene Deletion ; Genetic Predisposition to Disease ; Humans ; Lung Neoplasms/enzymology ; Lung Neoplasms/ethnology ; Polymorphism, Single Nucleotide ; Taiwan

المؤلفون: Tan YH; Department of Life Science, National Taiwan Normal University, Taipei, Taiwan., Krishnaswamy S, Nandi S, Kanteti R, Vora S, Onel K, Hasina R, Lo FY, El-Hashani E, Cervantes G, Robinson M, Hsu HS, Kales SC, Lipkowitz S, Karrison T, Sattler M, Vokes EE, Wang YC, Salgia R

المصدر: PloS one [PLoS One] 2010 Jan 29; Vol. 5 (1), pp. e8972. Date of Electronic Publication: 2010 Jan 29.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Electronic Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

مواضيع طبية MeSH: Mutation, Missense*, ErbB Receptors/*genetics , Lung Neoplasms/*genetics , Proto-Oncogene Proteins c-cbl/*genetics , Proto-Oncogene Proteins c-met/*genetics , Receptors, Growth Factor/*genetics, Base Sequence ; Blotting, Western ; Cell Line, Tumor ; Chromosomes, Human, Pair 11 ; DNA Primers ; Flow Cytometry ; Humans ; Loss of Heterozygosity ; Mutagenesis, Site-Directed ; Paraffin Embedding

المؤلفون: Ray M; Department of Medicine, The University of Chicago, Section of Hematology/Oncology and Cancer Center, Chicago, Illinois 60637, USA. mandira.ray@uchospitals.edu, Salgia R, Vokes EE

المصدر: The oncologist [Oncologist] 2009 Nov; Vol. 14 (11), pp. 1116-30. Date of Electronic Publication: 2009 Nov 05.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 9607837 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1549-490X (Electronic) Linking ISSN: 10837159 NLM ISO Abbreviation: Oncologist Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents/*therapeutic use , Carcinoma, Non-Small-Cell Lung/*drug therapy , ErbB Receptors/*antagonists & inhibitors , Lung Neoplasms/*drug therapy , Protein Kinase Inhibitors/*therapeutic use, Carcinoma, Non-Small-Cell Lung/pathology ; ErbB Receptors/metabolism ; Humans ; Lung Neoplasms/pathology