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المؤلفون: Pedro Luis Herrera, Negar Karimian, Patrick Gilon, Ya-Chi Huang, Marjan Slak Rupnik, Herbert Y. Gaisano, Zhong-Ping Feng
المصدر: Diabetes, Vol. 62, No 2 (2013) pp. 519-30
Diabetesمصطلحات موضوعية: Action Potentials/physiology, endocrine system diseases, Endocrinology, Diabetes and Metabolism, Hyperglycemia/blood/physiopathology, Action Potentials, Stimulation, Voltage-Gated Sodium Channels, Glucagon-Secreting Cells/pathology/physiology, Mice, 0302 clinical medicine, Exocytosis/physiology, ddc:576.5, Cells, Cultured, 0303 health sciences, Chemistry, Potassium channel, medicine.anatomical_structure, Diabetes Mellitus, Experimental/physiopathology, Potassium Channels, Voltage-Gated, Pancreas, medicine.drug, medicine.medical_specialty, Potassium Channels, Voltage-Gated/physiology, Glucagon/analysis/blood/secretion, 030209 endocrinology & metabolism, Glucagon, Exocytosis, Diabetes Mellitus, Experimental, Glucose Intolerance/physiopathology, 03 medical and health sciences, Diabetes Mellitus, Type 1/chemically induced/physiopathology, Diabetes mellitus, Internal medicine, Glucose Intolerance, Internal Medicine, medicine, Animals, 030304 developmental biology, Secretory Vesicles, Sodium channel, nutritional and metabolic diseases, Secretory Vesicles/physiology, medicine.disease, Streptozotocin, Electrophysiological Phenomena, Diabetes Mellitus, Type 1, Endocrinology, Islet Studies, Glucagon-Secreting Cells, Hyperglycemia, Voltage-Gated Sodium Channels/physiology, Hyperglucagonemia
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المؤلفون: Reinhard Jahn, Dirk Fasshauer
المصدر: Nature
Nature, vol. 490, no. 7419, pp. 201-207مصطلحات موضوعية: Vesicle fusion, Vesicle docking, Biology, Synaptic vesicle, Models, Biological, Exocytosis, Synaptotagmin 1, Article, Synaptotagmins, 03 medical and health sciences, 0302 clinical medicine, Animals, Calcium/metabolism, Exocytosis/physiology, Humans, Lipid Metabolism, SNARE Proteins/chemistry, SNARE Proteins/metabolism, Synaptic Vesicles/physiology, 030304 developmental biology, 0303 health sciences, Multidisciplinary, Munc-18, Synapsin, Cell biology, Calcium, Synaptic Vesicles, SNARE Proteins, 030217 neurology & neurosurgery
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfc690028bd6bd724305ed21d1f4e561
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المؤلفون: Iglesias José, Barg Sebastian, Vallois David, Lahiri Shawon, Roger Catherine, Yessoufou Akadiri, Pradevand Sylvain, McDonald Angela, Bonal Claire, Reimann Frank, Gribble Fiona, Debril Marie Bernard, Metzger Daniel, Chambon Pierre, Herrera Pedro, Rutter Guy A., Prentki Marc, Thorens Bernard, Wahli Walter
المصدر: The Journal of clinical investigation
Journal of Clinical Investigation, Vol. 122, No 11 (2012) pp. 4105-17
Journal of Clinical Investigationمصطلحات موضوعية: Male, medicine.medical_specialty, medicine.medical_treatment, Insulin-Secreting Cells/cytology/secretion, Golgi Apparatus, Adipose tissue, Biology, Filamentous actin, Exocytosis, 03 medical and health sciences, Mice, 0302 clinical medicine, Insulin resistance, Insulin-Secreting Cells, Internal medicine, Insulin Secretion, medicine, Hyperinsulinemia, Insulin, Animals, Exocytosis/physiology, ddc:576.5, Protein Kinase C/genetics/metabolism, PPAR delta, Glucose/genetics/metabolism, Golgi Apparatus/genetics/metabolism, PPAR-beta, Protein Kinase C, 030304 developmental biology, 0303 health sciences, PPAR delta/genetics/metabolism, Gene Expression Profiling, General Medicine, medicine.disease, Actin cytoskeleton, Insulin/genetics/secretion, Actins, Mice, Mutant Strains, PPAR-beta/genetics/metabolism, Glucose, medicine.anatomical_structure, Endocrinology, Actins/genetics/metabolism, 030220 oncology & carcinogenesis, Female, Pancreas, Research Article
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المساهمون: Universidad de Cantabria
المصدر: PLoS ONE, Vol 7, Iss 3, p e32282 (2012)
PLoS ONE, 2012, 7(3), e32282
UCrea Repositorio Abierto de la Universidad de Cantabria
Universidad de Cantabria (UC)
PloS one, 7 (3
PLoS ONEمصطلحات موضوعية: Anatomy and Physiology, Time Factors, medicine.medical_treatment, Enteroendocrine cell, Biochemistry, Mice, Endocrinology, Insulin, Multidisciplinary, Glucagon secretion, Animal Models, Glucagon -- secretion, medicine.anatomical_structure, Models, Animal, Medicine, Research Article, Computer Modeling, medicine.medical_specialty, Insulin -- metabolism, Science, chemistry.chemical_element, Endocrine System, Biology, Calcium, Glucagon, Exocytosis, Model Organisms, Internal medicine, medicine, Chimie, Animals, Secretion, Endocrine Physiology, Secretory Vesicles, Pancreatic islets, Computational Biology, Glucose -- metabolism, Secretory Vesicles -- metabolism, Glucagon-Secreting Cells -- metabolism, Kinetics, Glucose, chemistry, Glucagon-Secreting Cells, Computer Science, Exocytosis -- physiology, Calcium -- metabolism, Hormone
وصف الملف: 1 full-text file(s): application/pdf
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المصدر: The Journal of Cell Biology
Journal of Cell Biology, vol. 188, no. 3, pp. 401-413مصطلحات موضوعية: Vesicle fusion, Synaptosomal-Associated Protein 25, Physiology, Synaptobrevin, Biology, Models, Biological, Exocytosis, Article, R-SNARE Proteins, Mice, ddc:570, Animals, Calcium/metabolism, Exocytosis/physiology, Mice, Knockout, Qa-SNARE Proteins/genetics, Qa-SNARE Proteins/metabolism, R-SNARE Proteins/genetics, R-SNARE Proteins/metabolism, Rats, SNARE Proteins/genetics, SNARE Proteins/metabolism, Secretory Vesicles/genetics, Secretory Vesicles/metabolism, Synaptosomal-Associated Protein 25/genetics, Synaptosomal-Associated Protein 25/metabolism, Research Articles, Qa-SNARE Proteins, Secretory Vesicles, SNAP25, Munc-18, Cell Biology, Kiss-and-run fusion, Cell biology, Porosome, Calcium, ddc:620, SNARE Proteins, SNARE complex
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ef744d749eaa66b8abfffbf62db3c61
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المؤلفون: Yves Benoît Mattenberger, Kyu Sang Park, Piero Marchetti, Andreas Wiederkehr, Jean-Claude Martinou, Clare L. Kirkpatrick, Nicolas Demaurex, Claes B. Wollheim
المصدر: Journal of Biological Chemistry, Vol. 283, No 48 (2008) pp. 33347-56
مصطلحات موضوعية: Mitochondrion, ddc:616.07, Biochemistry, Mitochondrial apoptosis-induced channel, Membrane Fusion, Mitochondrial Membrane Transport Proteins, GTP Phosphohydrolases, Adenosine Triphosphate, Insulin-Secreting Cells, Insulin Secretion, MFN1, Exocytosis/physiology, Insulin, biology, Mitochondrial Proteins/genetics/metabolism, Membrane Proteins/genetics/metabolism, Insulin/genetics/secretion, Cell biology, Mitochondria, Metabolism and Bioenergetics, Insulin-Secreting Cells/cytology/metabolism, Mitochondrial fission, ATP–ADP translocase, Signal Transduction, Adenosine Triphosphate/genetics/metabolism, Exocytosis, Mitochondrial Proteins, Mitochondrial membrane transport protein, Cell Line, Tumor, Animals, Humans, Glucose/genetics/metabolism, Secretory Vesicles/genetics/metabolism, Membrane Transport Proteins/genetics/metabolism, Rats, Wistar, ddc:612, Molecular Biology, Mitochondria/genetics/metabolism, GTP Phosphohydrolases/genetics/metabolism, Signal Transduction/physiology, Secretory Vesicles, Membrane Proteins, Membrane Transport Proteins, Cell Biology, Rats, Cytosol, Glucose, Mitochondrial permeability transition pore, biology.protein, Membrane Fusion/physiology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a957684c2f41402177f10d43d1a4370
https://pubmed.ncbi.nlm.nih.gov/18832378 -
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المؤلفون: Benoit R. Gauthier, Claes B. Wollheim
المصدر: American Journal of Physiology. Endocrinology and Metabolism, Vol. 295, No 6 (2008) pp. E1279-86
مصطلحات موضوعية: medicine.medical_specialty, Calcium/metabolism, Insulin/metabolism, Physiology, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, chemistry.chemical_element, Biology, Calcium, Models, Biological, Synaptotagmin 1, Exocytosis, Synaptotagmins/metabolism/physiology, Synaptotagmins, Physiology (medical), Internal medicine, Insulin-Secreting Cells, medicine, Exocytosis/physiology, Animals, Humans, Insulin, Protein Isoforms, Protein Isoforms/metabolism/physiology, ddc:612, geography, geography.geographical_feature_category, Insulin-Secreting Cells/metabolism/physiology, Vesicle, Munc-18, Islet, Endocrinology, chemistry, Protein Binding
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65ebce12fc03141e300632feb9c03d16
https://pubmed.ncbi.nlm.nih.gov/18713958 -
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المصدر: Traffic, Vol. 9, No 5 (2008) pp. 813-32
مصطلحات موضوعية: Vesicle-Associated Membrane Protein 2, medicine.medical_treatment, Vesicular Transport Proteins, Syntaxin 1, Biochemistry, Serine, Structural Biology, Insulin-Secreting Cells, Exocytosis/physiology, Glucose/metabolism, Insulin, ddc:576.5, Munc18 Proteins/genetics/metabolism, Anti-Bacterial Agents/metabolism, Transfection, Synaptosomal-Associated Protein 25/metabolism, Cell biology, Anti-Bacterial Agents, Secretory Vesicles/chemistry/metabolism, Doxycycline, symbols, Insulin-Secreting Cells/cytology/metabolism, RNA Interference, medicine.medical_specialty, Insulin/metabolism, Synaptosomal-Associated Protein 25, Vesicular Transport Proteins/genetics/metabolism, Biology, Exocytosis, Cell Line, Syntaxin 1/metabolism, symbols.namesake, Munc18 Proteins, Internal medicine, Genetics, medicine, Autophagy, Animals, Humans, Protein kinase A, Molecular Biology, Vesicle-Associated Membrane Protein 2/metabolism, Secretory Vesicles, Vacuoles/metabolism, Doxycycline/metabolism, Munc-18, Cell Biology, Golgi apparatus, Rats, Endocrinology, Glucose, Vacuoles
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المؤلفون: Steve J. Charette, Pierre Cosson
المصدر: Traffic, Vol. 9, No 4 (2008) pp. 588-96
مصطلحات موضوعية: Lysosomes/chemistry/metabolism/ultrastructure, Adaptor Protein Complex 3, Endosome, Cellular differentiation, Biochemistry, Clathrin, Exocytosis, Dictyostelium discoideum, Structural Biology, Lysosome, Genetics, Lysosomal storage disease, medicine, Adaptor Protein Complex 3/genetics/metabolism, Animals, Exocytosis/physiology, Humans, Dictyostelium, Secretion, ddc:612, Molecular Biology, biology, Cell Biology, biology.organism_classification, medicine.disease, Actins, Cell biology, Protein Subunits, medicine.anatomical_structure, Phenotype, Actins/metabolism, biology.protein, Lysosomes, Dictyostelium/cytology/genetics/metabolism, Biogenesis, Protein Subunits/genetics/metabolism
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المؤلفون: Benoit R, Gauthier, Dominique L, Duhamel, Mariella, Iezzi, Sten, Theander, Frédéric, Saltel, Mitsunori, Fukuda, Bernhard, Wehrle-Haller, Claes B, Wollheim
المصدر: FASEB Journal, Vol. 22, No 1 (2008) pp. 194-206
مصطلحات موضوعية: Male, Calcium/metabolism, Rats Wistar, Insulin/metabolism, RNA Splicing, Exocytosis, Cell Line, Synaptotagmins/genetics/metabolism/physiology, Islets of Langerhans, Synaptotagmins, Insulin, Animals, Exocytosis/physiology, Glucose/metabolism, Rats, Wistar, ddc:612, Recombinant Proteins/genetics/metabolism, DNA Primers, Base Sequence, Reverse Transcriptase Polymerase Chain Reaction, Recombinant Proteins, Rats, Glucose, Calcium, Islets of Langerhans/metabolism
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