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المؤلفون: Abigail Camenisch, Isabella R. Blum, Stefanie A.T. Mitchell, Meng-Han Wu, Christopher M. Cox, Matthew T Ollerton, Pawel R. Kiela, Marco Padilla-Rodriguez, Vanessa Figliuolo da Paz, John Muller, Curtis A. Thorne, Jean M. Wilson, Samina Momtaz
المصدر: Dev Biol
مصطلحات موضوعية: Male, Endosome, Endocytic cycle, Crypt, Endosomes, Biology, Stem cell marker, Article, Mice, Lysosome, medicine, Animals, Intestinal Mucosa, Wnt Signaling Pathway, Molecular Biology, Cell Proliferation, Glycoproteins, Mice, Knockout, Microfilament Proteins, Wnt signaling pathway, LGR5, Cell Differentiation, Cell Biology, Intestinal epithelium, Cell biology, Intestines, Wnt Proteins, Enterocytes, medicine.anatomical_structure, Female, Developmental Biology
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المؤلفون: Yuanhong Xu, Zhongbo Zhang, Chenghai Zhao
المصدر: Cancer Medicine
Cancer Medicine, Vol 10, Iss 10, Pp 3332-3345 (2021)مصطلحات موضوعية: 0301 basic medicine, Male, Cancer Research, Cell, pancreatic cancer, Deoxycytidine, 0302 clinical medicine, ATP Binding Cassette Transporter, Subfamily G, Member 2, RC254-282, beta Catenin, Original Research, Cancer Biology, Gene knockdown, biology, Chemistry, CD24, Wnt signaling pathway, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, chemoresistance, Middle Aged, Up-Regulation, Gene Expression Regulation, Neoplastic, medicine.anatomical_structure, Hyaluronan Receptors, Oncology, 030220 oncology & carcinogenesis, Neoplastic Stem Cells, Female, Stem cell, 03 medical and health sciences, stemness, Downregulation and upregulation, Pancreatic cancer, Cell Line, Tumor, medicine, Humans, Radiology, Nuclear Medicine and imaging, Cell Proliferation, Fzd7/Wnt7b, CD44, CD24 Antigen, medicine.disease, Gemcitabine, Frizzled Receptors, Pancreatic Neoplasms, Wnt Proteins, 030104 developmental biology, Drug Resistance, Neoplasm, biology.protein, Cancer research, sense organs
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المؤلفون: Johannes Beckers, Fabian J. Theis, Wolfgang Enard, Maren Büttner, Christoph Ziegenhain, Heiko Lickert, Fien M. Verhamme, Lena Oppenländer, Anika Böttcher, Sophie Tritschler, Oliver Eickelberg, Michael Sterr, Andrea C. Schamberger, Alexandra Aliluev, Martin Irmler, Steffen Sass, Ingo Burtscher
المصدر: Nat. Cell Biol. 23, 23-31 (2021)
مصطلحات موضوعية: inorganic chemicals, Male, Paneth Cells, Lineage (genetic), Enteroendocrine Cells, Enteroendocrine cell, Biology, digestive system, Receptors, G-Protein-Coupled, Mice, 03 medical and health sciences, 0302 clinical medicine, Single-cell analysis, Cell polarity, medicine, Animals, Cell Lineage, Cell Self Renewal, Intestinal Mucosa, beta Catenin, 030304 developmental biology, Mice, Knockout, 0303 health sciences, Gene Expression Profiling, Stem Cells, Wnt signaling pathway, LGR5, Cell Polarity, Cell Biology, Cell biology, Mice, Inbred C57BL, Wnt Proteins, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Paneth cell, Female, Single-Cell Analysis, Stem cell
وصف الملف: application/pdf
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المؤلفون: Morgane Le Rolle, Anne-Amandine Chassot, Pam Siggers, Filippo Massa, Marie-Christine Chaboissier, Bon-Kyoung Koo, Andreas Schedl, Hans Clevers, Agnès Loubat, Laurent Turchi, Andy Greenfield
المساهمون: Institut de Biologie Valrose (IBV), Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS), Institut Necker Enfants-Malades (INEM - UM 111 (UMR 8253 / U1151)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), MRC Harwell Institute [UK], Hubrecht Institute [Utrecht, Netherlands], University Medical Center [Utrecht]-Royal Netherlands Academy of Arts and Sciences (KNAW), Université Nice Sophia Antipolis (1965 - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Côte d'Azur (UCA), ANR-20-CE14-0022,ARDIGERM,Acide rétinoïque dans la différenciation des cellules germinales et la méiose(2020), ANR-13-BSV2-0017,ARGONADS,Acide rétinoique et devenir des cellules germinales(2013), ANR-11-LABX-0028,SIGNALIFE,Réseau d'Innovation sur les Voies de Signalisation en Sciences de la Vie(2011), Chaboissier, Marie-Christine, Acide rétinoïque dans la différenciation des cellules germinales et la méiose - - ARDIGERM2020 - ANR-20-CE14-0022 - AAPG2020 - VALID, Blanc 2013 - Acide rétinoique et devenir des cellules germinales - - ARGONADS2013 - ANR-13-BSV2-0017 - Blanc 2013 - VALID, Centres d'excellences - Réseau d'Innovation sur les Voies de Signalisation en Sciences de la Vie - - SIGNALIFE2011 - ANR-11-LABX-0028 - LABX - VALID, Hubrecht Institute for Developmental Biology and Stem Cell Research, Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), CHASSOT, Anne Amandine
المصدر: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2021, 118 (30), pp.e2023376118. ⟨10.1073/pnas.2023376118⟩
Proceedings of the National Academy of Sciences of the United States of America, 2021, 118 (30), pp.e2023376118. ⟨10.1073/pnas.2023376118⟩
Proceedings of the National Academy of Sciences of the United States of America, 118(30). National Academy of Sciencesمصطلحات موضوعية: Male, Pluripotent Stem Cells, germ cells, beta Catenin/genetics, Pluripotency & Differentiation, [SDV]Life Sciences [q-bio], Biology, Inbred C57BL, 03 medical and health sciences, Mice, 0302 clinical medicine, Meiosis, Primordial germ cell, medicine, Animals, Germ Cells/cytology, Wnt Proteins/genetics, Gametogenesis, beta Catenin, 030304 developmental biology, 0303 health sciences, Multidisciplinary, Wnt signaling pathway, Cell Differentiation, Pluripotent Stem Cells/cytology, WNT/β-catenin, differentiation, Cell cycle, Biological Sciences, POU5F1/OCT4, Embryonic stem cell, Cell biology, Sexual reproduction, [SDV] Life Sciences [q-bio], Mice, Inbred C57BL, Wnt Proteins, medicine.anatomical_structure, Female, ovary, Signal transduction, Octamer Transcription Factor-3, 030217 neurology & neurosurgery, Germ cell, Octamer Transcription Factor-3/genetics, Developmental Biology
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32b8b5f82de617033f1b5409e3c126ab
https://hal.archives-ouvertes.fr/hal-03357217/document -
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المؤلفون: Pirjo Nummela, Colin Nixon, William C. Clark, Ella Gilchrist, Simon J. Leedham, Michael C. Hodder, Nalle Pentinmikko, Arafath Kaja Najumudeen, Nathalie Sphyris, E. Yvonne Jones, Jean-Paul Vincent, Hans Clevers, Nicky J. Willis, Alexander Raven, Kristina Kirschner, Dustin J. Flanagan, Paul V. Fish, Emma Minnee, Pekka Katajisto, Ville Hietakangas, Owen J. Sansom, Christine Perret, Lynn McGarry, Nadia Nasreddin, Rachel A. Ridgway, Ann C. Williams, Kathryn Gilroy, Kalle Luopajärvi, Sandra Scharaw, Béatrice Romagnolo, Marianne Lähde, Ari Ristimäki, Johanna Englund, Anna Taylor Webb, Kari Alitalo, Ann Hedley
المساهمون: Hubrecht Institute for Developmental Biology and Stem Cell Research, Institute of Biotechnology (-2009), University of Helsinki, CAN-PRO - Translational Cancer Medicine Program, Centre of Excellence in Stem Cell Metabolism, Helsinki Institute of Life Science HiLIFE, Institute of Biotechnology, Juha Klefström / Principal Investigator, Research Programs Unit, Department of Pathology, Doctoral Programme in Biomedicine, ATG - Applied Tumor Genomics, Doctoral Programme in Integrative Life Science, HUSLAB, Kari Alitalo / Principal Investigator, Molecular and Integrative Biosciences Research Programme, Biosciences, Nutrient sensing laboratory
المصدر: Nature, 594(7863), 430-435. Nature Publishing Group
Flanagan, D J, Williams, A C, Katajisto, P K, Sampson, O J & al., E 2021, ' NOTUM from Apc-mutant cells biases clonal competition to initiate cancer ', Nature, vol. 594, pp. 430–435 (2021) . https://doi.org/10.1038/s41586-021-03525-zمصطلحات موضوعية: 0301 basic medicine, Male, HOMEOSTASIS, Cell, medicine.disease_cause, Cell Transformation, Inbred C57BL, Ligands, BETA-CATENIN, ACTIVATION, PATHWAY, Mice, 0302 clinical medicine, Conditioned, INTESTINE, Stem Cells/cytology, Wnt Signaling Pathway, Cell Competition/genetics, Esterases/antagonists & inhibitors, Mutation, Multidisciplinary, biology, Stem Cells, Cell Transformation, Neoplastic/genetics, Wnt signaling pathway, Esterases, Cell Differentiation, Neoplastic/genetics, Cell biology, Organoids, POLYPOSIS, medicine.anatomical_structure, Cell Transformation, Neoplastic, 030220 oncology & carcinogenesis, Disease Progression, Organoids/cytology, Female, Stem cell, Colorectal Neoplasms, STEM-CELLS, BONE-FORMATION, Adenoma, Beta-catenin, Genes, APC, 3122 Cancers, Crypt, Adenomatous Polyposis Coli Protein, WNT, 03 medical and health sciences, Cancer stem cell, Wnt Proteins/metabolism, medicine, Animals, Humans, Adenomatous Polyposis Coli Protein/genetics, Cell Proliferation, Adenoma/genetics, Colorectal Neoplasms/genetics, Notum, Culture Media, APC, Wnt Proteins, Mice, Inbred C57BL, 030104 developmental biology, Genes, Cell Competition, Culture Media, Conditioned, biology.protein, 1182 Biochemistry, cell and molecular biology
وصف الملف: application/pdf
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المؤلفون: Chenyao Li, Xinxin Chen, Guang Chen, Tao Liu
المصدر: Oncology Reports
مصطلحات موضوعية: Male, Cancer Research, Cell, Metastasis, Cell Movement, Cell Line, Tumor, Proto-Oncogene Proteins, medicine, Humans, papillary thyroid cancer, MTT assay, Thyroid Neoplasms, Cell Proliferation, Gene knockdown, Oncogene, lncRNA HOTAIRM1, Chemistry, Articles, General Medicine, Transfection, Middle Aged, Cell cycle, medicine.disease, Molecular medicine, Gene Expression Regulation, Neoplastic, Survival Rate, Wnt Proteins, MicroRNAs, miR-148a, medicine.anatomical_structure, Oncology, Lymphatic Metastasis, Cancer research, Female, Wnt10b, Signal Transduction
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المؤلفون: Gul Guner Akdogan, Duygu Harmanci, Merih Birlik, Ayse Kocak
المصدر: International Journal of Rheumatic Diseases. 23:1558-1567
مصطلحات موضوعية: Adult, Male, Pathology, medicine.medical_specialty, Disease, Scleroderma, Pathogenesis, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Rheumatology, Scleroderma, Limited, Fibrosis, medicine, Humans, 030212 general & internal medicine, skin and connective tissue diseases, Wnt Signaling Pathway, Aged, Aged, 80 and over, 030203 arthritis & rheumatology, Autoimmune disease, Kidney, Lung, integumentary system, business.industry, Wnt signaling pathway, Middle Aged, Prognosis, medicine.disease, Wnt Proteins, medicine.anatomical_structure, Case-Control Studies, Scleroderma, Diffuse, Disease Progression, Female, business
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المؤلفون: Wenlan Liu, Lilong Lin, Zhen-Ni Guo, Song Ta, Peng Zhang, Junlei Chang, Qingquan Gu, Feng-E Li, Zhihuan Li, Xianfang Rong, Yi Yang, Hang Jin, Chenqing Zheng, Yuan Zhang
المصدر: CNS Neuroscience & Therapeutics
مصطلحات موضوعية: blood‐brain barrier, signaling pathway, Male, 0301 basic medicine, FZD4, medicine.medical_treatment, single‐nucleotide polymorphism, Pharmacology, Blood–brain barrier, Polymorphism, Single Nucleotide, Brain Ischemia, Receptors, G-Protein-Coupled, 03 medical and health sciences, 0302 clinical medicine, Fibrinolytic Agents, Physiology (medical), ischemic stroke, medicine, Humans, Thrombolytic Therapy, Pharmacology (medical), Stroke, Aged, Cerebral Hemorrhage, Intracerebral hemorrhage, business.industry, Wnt signaling pathway, Genetic Variation, Original Articles, Thrombolysis, Middle Aged, medicine.disease, intracerebral hemorrhage, Wnt Proteins, Psychiatry and Mental health, 030104 developmental biology, medicine.anatomical_structure, WNT7A, Original Article, Administration, Intravenous, Female, Signal transduction, business, 030217 neurology & neurosurgery
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المؤلفون: Yurun Zhang, Tiancheng Fang, Vivian Y. Chang, Martina Roos, Lia Signaevskaia, Heather A. Himburg, Paulina K. Lin, Amara Pang, Mindy M. Kim, Joshua P. Sasine, Christina M. Termini, Orel Tabibi, Avradip Chatterjee, Michelle Li, Ramachandran Murali, John P. Chute, Nicollette J Setiawan
المصدر: Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)مصطلحات موضوعية: Male, Science, General Physics and Astronomy, Apoptosis, Bone Marrow Cells, General Biochemistry, Genetics and Molecular Biology, Article, Stress signalling, Mice, Bone Marrow, Neuropilin 1, medicine, Animals, Regeneration, Multidisciplinary, Chemistry, Regeneration (biology), Haematopoietic stem cells, Wnt signaling pathway, Hematopoietic stem cell, Cyclin-Dependent Kinase 5, Semaphorin-3A, General Chemistry, Hematopoietic Stem Cells, Cardiovascular biology, Neuropilin-1, Cell biology, Stem-cell research, Endothelial stem cell, Mice, Inbred C57BL, Wnt Proteins, Haematopoiesis, medicine.anatomical_structure, Female, Bone marrow, Stem cell, Transcriptome, Signal Transduction
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المؤلفون: Zhenrui Li, Anuradha Roy, Xiazhen Yu, Linhao Ruan, Xi C. He, Prashant Deshmukh, G. Sitta Sittampalam, Alan S. Gamis, Melinda Broward, Xiuling Lu, Jacqelyn Nemechek, Pengxu Qian, John M. Perry, Robin Ryan, Linheng Li, Andrea Moran, Fang Tao, Keith J. August, Mark Hembree, Thanh Huyen Tran, Zhiquan He, Rajeswari M. Kasi, Meng Zhao, Aparna Venkatraman, Dong Xu, Erin M. Guest, Debra Dukes, Chi Thanh Nguyen, Shiyuan Chen, Jennifer Pace, Scott Weir, Sheng Ding, Andrew K. Godwin, Ariel Paulson, Tara L. Lin, Kealan Schroeder
المصدر: Nat Cell Biol
مصطلحات موضوعية: Male, Myeloid, Apoptosis, Biology, medicine.disease_cause, Article, Mice, Phosphatidylinositol 3-Kinases, 03 medical and health sciences, 0302 clinical medicine, Immune system, Tumor Cells, Cultured, medicine, Animals, Humans, Doxorubicin, Progenitor cell, beta Catenin, Cell Proliferation, 030304 developmental biology, Mice, Knockout, 0303 health sciences, Antibiotics, Antineoplastic, PTEN Phosphohydrolase, Wnt signaling pathway, Cell Biology, Xenograft Model Antitumor Assays, Cell biology, Wnt Proteins, Leukemia, Myeloid, Acute, medicine.anatomical_structure, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Catenin, Neoplastic Stem Cells, Female, Stem cell, Carcinogenesis, Proto-Oncogene Proteins c-akt, medicine.drug