المؤلفون: Johannes Beckers, Fabian J. Theis, Wolfgang Enard, Maren Büttner, Christoph Ziegenhain, Heiko Lickert, Fien M. Verhamme, Lena Oppenländer, Anika Böttcher, Sophie Tritschler, Oliver Eickelberg, Michael Sterr, Andrea C. Schamberger, Alexandra Aliluev, Martin Irmler, Steffen Sass, Ingo Burtscher

المصدر: Nat. Cell Biol. 23, 23-31 (2021)

مصطلحات موضوعية: inorganic chemicals, Male, Paneth Cells, Lineage (genetic), Enteroendocrine Cells, Enteroendocrine cell, Biology, digestive system, Receptors, G-Protein-Coupled, Mice, 03 medical and health sciences, 0302 clinical medicine, Single-cell analysis, Cell polarity, medicine, Animals, Cell Lineage, Cell Self Renewal, Intestinal Mucosa, beta Catenin, 030304 developmental biology, Mice, Knockout, 0303 health sciences, Gene Expression Profiling, Stem Cells, Wnt signaling pathway, LGR5, Cell Polarity, Cell Biology, Cell biology, Mice, Inbred C57BL, Wnt Proteins, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Paneth cell, Female, Single-Cell Analysis, Stem cell

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b15847ba51c5ee6f9baf2b0a1d5082f
https://doi.org/10.1038/s41556-020-00617-2

المؤلفون: Morgane Le Rolle, Anne-Amandine Chassot, Pam Siggers, Filippo Massa, Marie-Christine Chaboissier, Bon-Kyoung Koo, Andreas Schedl, Hans Clevers, Agnès Loubat, Laurent Turchi, Andy Greenfield

المساهمون: Institut de Biologie Valrose (IBV), Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS), Institut Necker Enfants-Malades (INEM - UM 111 (UMR 8253 / U1151)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), MRC Harwell Institute [UK], Hubrecht Institute [Utrecht, Netherlands], University Medical Center [Utrecht]-Royal Netherlands Academy of Arts and Sciences (KNAW), Université Nice Sophia Antipolis (1965 - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Côte d'Azur (UCA), ANR-20-CE14-0022,ARDIGERM,Acide rétinoïque dans la différenciation des cellules germinales et la méiose(2020), ANR-13-BSV2-0017,ARGONADS,Acide rétinoique et devenir des cellules germinales(2013), ANR-11-LABX-0028,SIGNALIFE,Réseau d'Innovation sur les Voies de Signalisation en Sciences de la Vie(2011), Chaboissier, Marie-Christine, Acide rétinoïque dans la différenciation des cellules germinales et la méiose - - ARDIGERM2020 - ANR-20-CE14-0022 - AAPG2020 - VALID, Blanc 2013 - Acide rétinoique et devenir des cellules germinales - - ARGONADS2013 - ANR-13-BSV2-0017 - Blanc 2013 - VALID, Centres d'excellences - Réseau d'Innovation sur les Voies de Signalisation en Sciences de la Vie - - SIGNALIFE2011 - ANR-11-LABX-0028 - LABX - VALID, Hubrecht Institute for Developmental Biology and Stem Cell Research, Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), CHASSOT, Anne Amandine

المصدر: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2021, 118 (30), pp.e2023376118. ⟨10.1073/pnas.2023376118⟩
Proceedings of the National Academy of Sciences of the United States of America, 2021, 118 (30), pp.e2023376118. ⟨10.1073/pnas.2023376118⟩
Proceedings of the National Academy of Sciences of the United States of America, 118(30). National Academy of Sciences

مصطلحات موضوعية: Male, Pluripotent Stem Cells, germ cells, beta Catenin/genetics, Pluripotency & Differentiation, [SDV]Life Sciences [q-bio], Biology, Inbred C57BL, 03 medical and health sciences, Mice, 0302 clinical medicine, Meiosis, Primordial germ cell, medicine, Animals, Germ Cells/cytology, Wnt Proteins/genetics, Gametogenesis, beta Catenin, 030304 developmental biology, 0303 health sciences, Multidisciplinary, Wnt signaling pathway, Cell Differentiation, Pluripotent Stem Cells/cytology, WNT/β-catenin, differentiation, Cell cycle, Biological Sciences, POU5F1/OCT4, Embryonic stem cell, Cell biology, Sexual reproduction, [SDV] Life Sciences [q-bio], Mice, Inbred C57BL, Wnt Proteins, medicine.anatomical_structure, Female, ovary, Signal transduction, Octamer Transcription Factor-3, 030217 neurology & neurosurgery, Germ cell, Octamer Transcription Factor-3/genetics, Developmental Biology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32b8b5f82de617033f1b5409e3c126ab
https://hal.archives-ouvertes.fr/hal-03357217/document

المؤلفون: Pirjo Nummela, Colin Nixon, William C. Clark, Ella Gilchrist, Simon J. Leedham, Michael C. Hodder, Nalle Pentinmikko, Arafath Kaja Najumudeen, Nathalie Sphyris, E. Yvonne Jones, Jean-Paul Vincent, Hans Clevers, Nicky J. Willis, Alexander Raven, Kristina Kirschner, Dustin J. Flanagan, Paul V. Fish, Emma Minnee, Pekka Katajisto, Ville Hietakangas, Owen J. Sansom, Christine Perret, Lynn McGarry, Nadia Nasreddin, Rachel A. Ridgway, Ann C. Williams, Kathryn Gilroy, Kalle Luopajärvi, Sandra Scharaw, Béatrice Romagnolo, Marianne Lähde, Ari Ristimäki, Johanna Englund, Anna Taylor Webb, Kari Alitalo, Ann Hedley

المساهمون: Hubrecht Institute for Developmental Biology and Stem Cell Research, Institute of Biotechnology (-2009), University of Helsinki, CAN-PRO - Translational Cancer Medicine Program, Centre of Excellence in Stem Cell Metabolism, Helsinki Institute of Life Science HiLIFE, Institute of Biotechnology, Juha Klefström / Principal Investigator, Research Programs Unit, Department of Pathology, Doctoral Programme in Biomedicine, ATG - Applied Tumor Genomics, Doctoral Programme in Integrative Life Science, HUSLAB, Kari Alitalo / Principal Investigator, Molecular and Integrative Biosciences Research Programme, Biosciences, Nutrient sensing laboratory

المصدر: Nature, 594(7863), 430-435. Nature Publishing Group
Flanagan, D J, Williams, A C, Katajisto, P K, Sampson, O J & al., E 2021, ' NOTUM from Apc-mutant cells biases clonal competition to initiate cancer ', Nature, vol. 594, pp. 430–435 (2021) . https://doi.org/10.1038/s41586-021-03525-z

مصطلحات موضوعية: 0301 basic medicine, Male, HOMEOSTASIS, Cell, medicine.disease_cause, Cell Transformation, Inbred C57BL, Ligands, BETA-CATENIN, ACTIVATION, PATHWAY, Mice, 0302 clinical medicine, Conditioned, INTESTINE, Stem Cells/cytology, Wnt Signaling Pathway, Cell Competition/genetics, Esterases/antagonists & inhibitors, Mutation, Multidisciplinary, biology, Stem Cells, Cell Transformation, Neoplastic/genetics, Wnt signaling pathway, Esterases, Cell Differentiation, Neoplastic/genetics, Cell biology, Organoids, POLYPOSIS, medicine.anatomical_structure, Cell Transformation, Neoplastic, 030220 oncology & carcinogenesis, Disease Progression, Organoids/cytology, Female, Stem cell, Colorectal Neoplasms, STEM-CELLS, BONE-FORMATION, Adenoma, Beta-catenin, Genes, APC, 3122 Cancers, Crypt, Adenomatous Polyposis Coli Protein, WNT, 03 medical and health sciences, Cancer stem cell, Wnt Proteins/metabolism, medicine, Animals, Humans, Adenomatous Polyposis Coli Protein/genetics, Cell Proliferation, Adenoma/genetics, Colorectal Neoplasms/genetics, Notum, Culture Media, APC, Wnt Proteins, Mice, Inbred C57BL, 030104 developmental biology, Genes, Cell Competition, Culture Media, Conditioned, biology.protein, 1182 Biochemistry, cell and molecular biology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5733edf6d5fc44fd62aea7978eb694e
https://pure.knaw.nl/portal/en/publications/69a3582f-fc29-4f40-bc5f-17ba7825a11a

المؤلفون: Gill Holdsworth, Hollie Allison, Laoise M. McNamara

المصدر: BMC Molecular and Cell Biology, Vol 21, Iss 1, Pp 1-15 (2020)
BMC Molecular and Cell Biology

مصطلحات موضوعية: 0301 basic medicine, Osteoclastogenesis, Oscillatory fluid flow, Cathepsin K, Mice, chemistry.chemical_compound, 0302 clinical medicine, Osteogenesis, biology, lcsh:Cytology, Intracellular Signaling Peptides and Proteins, Up-Regulation, Resorption, medicine.anatomical_structure, RANKL, Osteocyte, Female, Signal Transduction, Research Article, musculoskeletal diseases, medicine.medical_specialty, Cell signaling, medicine.drug_class, Sclerostin antibody, 030209 endocrinology & metabolism, Osteocytes, Bone resorption, CCN Intercellular Signaling Proteins, Mechanobiology, 03 medical and health sciences, Osteoclast, Proto-Oncogene Proteins, Internal medicine, medicine, Animals, Bone Resorption, lcsh:QH573-671, Molecular Biology, Adaptor Proteins, Signal Transducing, NFATC Transcription Factors, RANK Ligand, Osteoprotegerin, Membrane Proteins, Estrogen deficiency, Estrogens, Cell Biology, Antibodies, Neutralizing, Chemokine CXCL12, Coculture Techniques, Mice, Inbred C57BL, Wnt Proteins, 030104 developmental biology, Endocrinology, Gene Expression Regulation, chemistry, Estrogen, Culture Media, Conditioned, biology.protein, Sclerostin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88196f8d32cc423202c9fffd3f78c148
http://link.springer.com/article/10.1186/s12860-020-00322-w

المؤلفون: Yurun Zhang, Tiancheng Fang, Vivian Y. Chang, Martina Roos, Lia Signaevskaia, Heather A. Himburg, Paulina K. Lin, Amara Pang, Mindy M. Kim, Joshua P. Sasine, Christina M. Termini, Orel Tabibi, Avradip Chatterjee, Michelle Li, Ramachandran Murali, John P. Chute, Nicollette J Setiawan

المصدر: Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)

مصطلحات موضوعية: Male, Science, General Physics and Astronomy, Apoptosis, Bone Marrow Cells, General Biochemistry, Genetics and Molecular Biology, Article, Stress signalling, Mice, Bone Marrow, Neuropilin 1, medicine, Animals, Regeneration, Multidisciplinary, Chemistry, Regeneration (biology), Haematopoietic stem cells, Wnt signaling pathway, Hematopoietic stem cell, Cyclin-Dependent Kinase 5, Semaphorin-3A, General Chemistry, Hematopoietic Stem Cells, Cardiovascular biology, Neuropilin-1, Cell biology, Stem-cell research, Endothelial stem cell, Mice, Inbred C57BL, Wnt Proteins, Haematopoiesis, medicine.anatomical_structure, Female, Bone marrow, Stem cell, Transcriptome, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e062fda3492e51b9c9ca50666fe28924
http://europepmc.org/articles/PMC8635308

المؤلفون: Mahir Mohiuddin, Shannon E. Anderson, Woojin M. Han, Andrés J. García, Young C. Jang

المصدر: Acta Biomater

مصطلحات موضوعية: Male, Satellite Cells, Skeletal Muscle, Duchenne muscular dystrophy, Green Fluorescent Proteins, Muscle Fibers, Skeletal, 0206 medical engineering, Biomedical Engineering, macromolecular substances, 02 engineering and technology, Biochemistry, Regenerative medicine, Article, Cell Line, Polyethylene Glycols, Maleimides, Biomaterials, Mice, Cell Movement, Animals, Humans, Regeneration, Medicine, Muscle, Skeletal, Molecular Biology, Crosses, Genetic, Cell Proliferation, business.industry, Regeneration (biology), Skeletal muscle, Hydrogels, Cell migration, General Medicine, 021001 nanoscience & nanotechnology, medicine.disease, 020601 biomedical engineering, Recombinant Proteins, Cell biology, Mice, Inbred C57BL, Wnt Proteins, Transplantation, medicine.anatomical_structure, Self-healing hydrogels, Female, Stem cell, 0210 nano-technology, business, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8462319682f53c025de699fa9f57f73
https://doi.org/10.1016/j.actbio.2019.06.025

المؤلفون: Phillip C. Wong, Diana Wiesner, Francesco Roselli, Tobias M. Boeckers, Deniz Yilmazer-Hanke, Barbara Commisso, Linyun Tang, Albert C. Ludolph, Jochen H. Weishaupt, Najwa Ouali Alami, Luc Dupuis, David Bayer, Bernd Baumann, Thomas Wirth

المساهمون: University of Ulm (UUlm), German Research Center for Neurodegenerative Diseases - Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Mécanismes Centraux et Périphériques de la Neurodégénérescence, Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM), Johns Hopkins University School of Medicine [Baltimore], Dieterle, Stéphane

المصدر: Life science alliance 3(11), e201900571 (2020). doi:10.26508/lsa.201900571
Life Science Alliance
Life Science Alliance, Life Science Alliance LLC, 2020, 3 (11), pp.e201900571. ⟨10.26508/lsa.201900571⟩
Life Science Alliance, 2020, 3 (11), pp.e201900571. ⟨10.26508/lsa.201900571⟩

مصطلحات موضوعية: 0301 basic medicine, Male, [SDV]Life Sciences [q-bio], Health, Toxicology and Mutagenesis, blood supply [Spine], Plant Science, metabolism [Spine], MESH: Spinal Cord, Pathogenesis, blood [Amyotrophic Lateral Sclerosis], Mice, Superoxide Dismutase-1, 0302 clinical medicine, TANK-binding kinase 1, MESH: Animals, Amyotrophic lateral sclerosis, MESH: Amyotrophic Lateral Sclerosis, MESH: Superoxide Dismutase, Research Articles, MESH: Superoxide Dismutase-1, Motor Neurons, metabolism [Superoxide Dismutase-1], Ecology, metabolism [Astrocytes], Chemistry, Chemogenetics, Cell biology, genetics [Superoxide Dismutase-1], [SDV] Life Sciences [q-bio], MESH: Wnt Proteins, WNT5A, medicine.anatomical_structure, Spinal Cord, Disease Progression, MESH: Disease Progression, Female, MESH: Spine, MESH: Motor Neurons, physiology [Motor Neurons], Research Article, metabolism [Spinal Cord], Cord, MESH: Mice, Transgenic, metabolism [Superoxide Dismutase], Mice, Transgenic, Biochemistry, Genetics and Molecular Biology (miscellaneous), Wnt-5a Protein, 03 medical and health sciences, metabolism [Wnt Proteins], MESH: Mice, Inbred C57BL, ddc:570, medicine, Animals, Humans, MESH: Mice, MESH: Humans, Superoxide Dismutase, metabolism [Amyotrophic Lateral Sclerosis], Amyotrophic Lateral Sclerosis, metabolism [Motor Neurons], physiology [Astrocytes], medicine.disease, Spinal cord, MESH: Wnt-5a Protein, Spine, MESH: Male, Wnt Proteins, MESH: Astrocytes, Mice, Inbred C57BL, Disease Models, Animal, 030104 developmental biology, WNT7A, Astrocytes, MESH: Disease Models, Animal, MESH: Female, metabolism [Wnt-5a Protein], 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93218dfe1100975b7bc1fb24ea761df4
https://pub.dzne.de/record/164314

المؤلفون: Zhong-Fa Lu, Lijuan Zhou, Jing Jing, Lijuan Yu, Han Wang, Xian-Jie Wu

المصدر: Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Scientific Reports

مصطلحات موضوعية: 0301 basic medicine, Adult, Male, Adolescent, Lymphoid Enhancer-Binding Factor 1, Cell, lcsh:Medicine, Outer root sheath, Article, 03 medical and health sciences, Mice, Young Adult, Cornus, Downregulation and upregulation, Proto-Oncogene Proteins, medicine, Loose Anagen Hair Syndrome, Animals, Humans, Glycosides, lcsh:Science, Wnt Signaling Pathway, Cells, Cultured, beta Catenin, Cell Proliferation, Multidisciplinary, integumentary system, Chemistry, lcsh:R, Wnt signaling pathway, Alopecia, Middle Aged, medicine.disease, In vitro, Cell biology, Mice, Inbred C57BL, Wnt Proteins, 030104 developmental biology, medicine.anatomical_structure, Hair loss, DKK1, Intercellular Signaling Peptides and Proteins, Female, lcsh:Q, Signal transduction, Hair Follicle, Hair

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc56d7aadcf4f24e2d2ceda364521b79
http://link.springer.com/article/10.1038/s41598-018-32138-2

المؤلفون: Bo Huang, Yi Fang, Ning Wang, Yabo Zhou, Haizeng Zhang, Tianzhen Zhang, Yuying Liu, Ke Tang, Huafeng Zhang, Nannan Zhou, Mengyu Liu, Jiadi Lv, Cong Li, Jiping Li, Jing Xie, Qiang Zhu, Xiaohan Liu, Yaoping Liu, Feiran Cheng, Longfei Ma, Zhenfeng Wang, Jingwei Ma

المصدر: The EMBO Journal

مصطلحات موضوعية: Carcinogenesis, Cell, Mice, SCID, Regenerative Medicine, Metastasis, Mice, 0302 clinical medicine, Mice, Inbred NOD, AC133 Antigen, Cancer, Mice, Inbred BALB C, 0303 health sciences, education.field_of_study, General Neuroscience, Wnt signaling pathway, Articles, Up-Regulation, DNA-Binding Proteins, medicine.anatomical_structure, MCF-7 Cells, Neoplastic Stem Cells, Female, Population, Biology, Article, General Biochemistry, Genetics and Molecular Biology, stemness, 03 medical and health sciences, Side population, Downregulation and upregulation, Cancer stem cell, Cell Line, Tumor, medicine, metastasis, Animals, Humans, BCL9L, microfluidic sorting, education, Molecular Biology, soft tumor cells, 030304 developmental biology, General Immunology and Microbiology, Aldehyde Dehydrogenase, medicine.disease, Mice, Inbred C57BL, Wnt Proteins, Cancer cell, Cancer research, Cell Adhesion, Polarity & Cytoskeleton, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b2770cd0668a3bb6ca5f2e96cc20bb0
https://doi.org/10.15252/embj.2020106123

المؤلفون: Lyse A. Norian, Selene Meza-Perez, Angelina I. Londono, Rebecca C. Arend, Carly Bess Scalise, Jaclyn A. Wall, William J. Turbitt, Ashwini A. Katre, Troy D. Randall

المصدر: Gynecol Oncol

مصطلحات موضوعية: 0301 basic medicine, T cell, CD8-Positive T-Lymphocytes, Article, 03 medical and health sciences, Mice, 0302 clinical medicine, Immune system, Lymphocytes, Tumor-Infiltrating, Cell Line, Tumor, Antineoplastic Combined Chemotherapy Protocols, medicine, Tumor Microenvironment, Animals, Enzyme Inhibitors, Immune Checkpoint Inhibitors, Wnt Signaling Pathway, beta Catenin, Mice, Knockout, Ovarian Neoplasms, Tumor microenvironment, business.industry, Wnt signaling pathway, Obstetrics and Gynecology, Membrane Proteins, Drug Synergism, medicine.disease, Immune checkpoint, Mice, Inbred C57BL, Wnt Proteins, 030104 developmental biology, medicine.anatomical_structure, Oncology, Tumor progression, 030220 oncology & carcinogenesis, Cancer research, Intercellular Signaling Peptides and Proteins, Female, Ovarian cancer, business, CD8, Acyltransferases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae1efcfd1d4fa3c182077b88951a4d86
https://pubmed.ncbi.nlm.nih.gov/33168307