المؤلفون: Clark DW; Centre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, EH8 9AG, Scotland., Okada Y; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Osaka, 565-0871, Japan.; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, 230-0045, Japan.; Laboratory of Statistical Immunology, Immunology Frontier Research Center (WPI-IFReC), Osaka University, Suita, Osaka, 565-0871, Japan., Moore KHS; deCODE genetics/Amgen Inc., Reykjavik 101, Iceland., Mason D; Bradford Institute for Health Research, Bradford Teaching Hospitals NHS Trust, Bradford, BD96RJ, UK., Pirastu N; Centre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, EH8 9AG, Scotland., Gandin I; Research Unit, Area Science Park, Trieste, 34149, Italy.; Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy., Mattsson H; Unit of Public Health Solutions, National Institute for Health and Welfare, Helsinki, Finland.; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland., Barnes CLK; Centre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, EH8 9AG, Scotland., Lin K; Nuffield Department of Population Health, University of Oxford, Oxford, OX3 7LF, UK., Zhao JH; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, CB2 0QQ, UK.; Cardiovascular Epidemiology Unit, Department of Public health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK., Deelen P; Department of Genetics, University Medical Centre Groningen, University of Groningen, Groningen, the Netherlands, Groningen, Groningen, 9700 RB, The Netherlands., Rohde R; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, 27514, USA., Schurmann C; The Charles Bronfman Institute for Personalized Medicine, Ichan School of Medicine at Mount Sinai, New York, NY, 10029, USA., Guo X; Division of Genomic Outcomes, Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, California, 90502, USA., Giulianini F; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, 02215, USA., Zhang W; Department of Epidemiology and Biostatistics, Imperial College London, London, W2 1PG, UK.; Department of Cardiology, Ealing Hospital, Middlesex, Middlesex, UB1 3HW, UK., Medina-Gomez C; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, 3015 CN, Netherlands.; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015 CN, Netherlands.; The Generation R Study Group, Erasmus University Medical Center, Rotterdam, 3015 CN, The Netherlands., Karlsson R; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, 17177, Sweden., Bao Y; Institute for Social and Economic Research, University of Essex, Colchester, CO4 3SQ, UK., Bartz TM; Cardiovascular Health Research Unit, Departments of Biostatistics and Medicine, University of Washington, Seattle, WA, 98101, USA., Baumbach C; Research Unit of Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, 85764, Germany., Biino G; Institute of Molecular Genetics, National Research Council of Italy, Pavia, 27100, Italy., Bixley MJ; Department of Biochemistry, University of Otago, Dunedin, 9054, New Zealand., Brumat M; Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy., Chai JF; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore, 117549, Singapore., Corre T; Department of Computational Biology, University of Lausanne, Lausanne, 1011, Switzerland.; Center for Primary Care and Public Health (Unisanté), University of Lausanne, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, 1015, Switzerland., Cousminer DL; Division of Human Genetics, Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Dekker AM; Department of Neurology, Brain Centre Rudolf Magnus, University Medical Centre Utrecht, Utrecht University, Utrecht, 3584 CX, The Netherlands., Eccles DA; Genomics Research Centre, School of Biomedical Sciences, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, 4059, Australia.; Malaghan Institute of Medical Research, Wellington, 6242, New Zealand., van Eijk KR; Department of Neurology, Brain Centre Rudolf Magnus, University Medical Centre Utrecht, Utrecht University, Utrecht, 3584 CX, The Netherlands., Fuchsberger C; Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lübeck, Bolzano, 39100, Italy., Gao H; Department of Epidemiology and Biostatistics, Imperial College London, London, W2 1PG, UK.; MRC-PHE Centre for Environment and Health, Imperial College London, London, W2 1PG, UK., Germain M; INSERM UMR_S 1166, Sorbonne Universités, Paris, 75013, France.; ICAN Institute for Cardiometabolism and Nutrition, Paris, 75013, France., Gordon SD; QIMR Berghofer Institute of Medical Research, Brisbane, Australia., de Haan HG; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, 2333 ZA, The Netherlands., Harris SE; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, EH8 9JZ, UK.; Centre for Genomic & Experimental Medicine, Institute of Genetics & Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK., Hofer E; Clinical Division of Neurogeriatrics, Department of Neurology, Medical University of Graz, Graz, 8036, Austria.; Institute of Medical Informatics, Statistics and Documentation, Medical University of Graz, Graz, 8036, Austria., Huerta-Chagoya A; CONACyT, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico, 03940, México., Igartua C; Department of Human Genetics, University of Chicago, Chicago, IL, 60637, USA., Jansen IE; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, Amsterdam, 1081 HV, The Netherlands.; Alzheimer Center Department of Neurology, VU University Medical Center, Amsterdam Neuroscience, Amsterdam, 1081HV, The Netherlands., Jia Y; Division of Genomic Outcomes, Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, California, 90502, USA., Kacprowski T; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, 17475, Germany.; Chair of Experimental Bioinformatics, TUM School of Life Sciences Weihenstephan, Technical University of Munich, Freising-Weihenstephan, 85354, Germany., Karlsson T; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, 75108, Uppsala, Sweden., Kleber ME; Vth Department of Medicine (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim, Heidelberg University, Mannheim, 68167, Germany., Li SA; Cancer Genomics Research Laboratory, Leidos Biomedical Research, Inc., Frederick National Lab for Cancer Research, Frederick, MD, USA., Li-Gao R; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, 2333 ZA, The Netherlands., Mahajan A; Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK., Matsuda K; Department of Computational Biology and Medical Sciences, Graduate school of Frontier Sciences, The University of Tokyo, Tokyo, 108-8639, Japan., Meidtner K; Department of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany.; German Center for Diabetes Research (DZD), München-Neuherberg, Germany., Meng W; Medical Research Institute, Ninewells Hospital and School of Medicine, University of Dundee, Dundee, UK., Montasser ME; Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland, School of Medicine, Baltimore, MD, 21201, USA.; Program for Personalized and Genomic Medicine, Department of Medicine, University of Maryland, School of Medicine, Baltimore, MD, 21201, USA., van der Most PJ; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, 9700 RB, The Netherlands., Munz M; Institute for Cardiogenetics, University of Lübeck, Lübeck, 23562, Germany.; DZHK (German Research Centre for Cardiovascular Research), partner site Hamburg/Lübeck/Kiel, Lübeck, 23562, Germany.; University Heart Center Luebeck, Lübeck, 23562, Germany.; Charité - University Medicine Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute for Dental and Craniofacial Sciences, Department of Periodontology and Synoptic Dentistry, Berlin, Germany., Nutile T; Institute of Genetics and Biophysics A. Buzzati-Traverso - CNR, Naples, 80131, Italy., Palviainen T; Finnish Institute for Molecular Medicine, University of Helsinki, Helsinki, Finland., Prasad G; Genomics and Molecular Medicine Unit, CSIR-Institute of Genomics and Integrative Biology, New Delhi, 110020, India., Prasad RB; Department of Clinical Sciences, Diabetes and Endocrinology, Lund University Diabetes Centre, Lund University, Skåne University Hospital, Malmö, 20502, Sweden., Priyanka TDS; Genomic Research on Complex diseases (GRC Group), CSIR-Centre for Cellular and Molecular Biology, Hyderabad, Telangana, 500007, India., Rizzi F; ePhood Scientific Unit, ePhood SRL, Bresso (Milano), 20091, Italy.; Department of Health Sciences, University of Milano, Milano, 20139, Italy., Salvi E; Department of Health Sciences, University of Milano, Milano, 20139, Italy.; Neuroalgology Unit, IRCCS Foundation Carlo Besta Neurological Institute, Milano, 20133, Italy., Sapkota BR; Department of Pediatrics, College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, 73104, USA., Shriner D; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, 20892-5635, USA., Skotte L; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, DK-2300, Denmark., Smart MC; Institute for Social and Economic Research, University of Essex, Colchester, CO4 3SQ, UK., Smith AV; Icelandic Heart Association, Kopavogur, 201, Iceland.; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, 101, Iceland., van der Spek A; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015 CN, Netherlands., Spracklen CN; Department of Genetics, University of North Carolina, Chapel Hill, NC, 27599, USA., Strawbridge RJ; Institute of Health and Wellbeing, University of Glasgow, Glasgow, G12 8RZ, UK.; Cardiovascular Medicine Unit, Department of Medicine Solna, Centre for Molecular Medicine, Karolinska Institutet, Stockholm, 171 76, Sweden., Tajuddin SM; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Baltimore City, Maryland, 21224, USA., Trompet S; Department of Cardiology, Leiden University Medical Center, Leiden, 2300 RC, the Netherlands.; Section of Gerontology and Geriatrics, Department of Internal Medicine, Leiden University Medical Center, Leiden, 2300RC, the Netherlands., Turman C; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, 02115, USA.; Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, MA, 02115, USA., Verweij N; University of Groningen, University Medical Center Groningen, Department of Cardiology, Ther Netherlands, Groningen, 9713 GZ, the Netherlands., Viberti C; Italian Institute for Genomic Medicine (IIGM) and Dept. Medical Sciences, University of Turin, Italy, Turin, 10126, Italy., Wang L; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, Saint Louis, MO, 63110-1093, USA., Warren HR; NIHR Barts Cardiovascular Biomedical Research Centre, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK.; Department of Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK., Wootton RE; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, BS8 2BN, UK.; School of Psychological Science, University of Bristol, Bristol, BS8 1TU, UK., Yanek LR; Department of Medicine, GeneSTAR Research Program, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA., Yao J; Division of Genomic Outcomes, Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, California, 90502, USA., Yousri NA; Department of Genetic Medicine, Weill Cornell Medicine Qatar, Doha, Qatar.; Computer and Systems Engineering, Alexandria University, Alexandria, Egypt., Zhao W; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, 48109, USA., Adeyemo AA; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, 20892-5635, USA., Afaq S; Department of Epidemiology and Biostatistics, Imperial College London, London, W2 1PG, UK., Aguilar-Salinas CA; Departamento de Endocrinología y Metabolismo, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico, 14080, México.; Unidad de Investigacion de Enfermades Metabolicas, Tecnologico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Monterrey, N.L., 64710, México., Akiyama M; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, 230-0045, Japan.; Department of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Fukuoka, 812-8582, Japan., Albert ML; Immunobiology of Dendritic Cells, Institut Pasteur, Paris, 75015, France.; Inserm U1223, Paris, 75015, France.; Centre for Translational Research, Institut Pasteur, Paris, 75015, France.; Department of Cancer Immunology, Genentech Inc, San Francisco, California, 94080, USA., Allison MA; Division of Preventive Medicine, Department of Family Medicine and Public Health, UC San Diego School of Medicine, La Jolla, California, 92093, USA., Alver M; Estonian Genome Center, University of Tartu, University of Tartu, Tartu, 51010, Estonia., Aung T; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore, 169856, Singapore.; Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore, 169857, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore, 119228, SG, Singapore., Azizi F; Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, 19839-63113, Iran., Bentley AR; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, 20892-5635, USA., Boeing H; Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany., Boerwinkle E; Health Science Center at Houston, UTHealth School of Public Health, University of Texas, Houston, TX, 77030, USA., Borja JB; USC-Office of Population Studies Foundation, Inc., Department of Nutrition and Dietetics, Talamban, University of San Carlos, Cebu City, 6000, Cebu, Philippines., de Borst GJ; Department of Vascular Surgery, Division of Surgical Specialties, University Medical Center Utrecht, University of Utrecht, Utrecht, Utrecht, 3584 CX, Netherlands., Bottinger EP; The Charles Bronfman Institute for Personalized Medicine, Ichan School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Digital Health Center, Hasso Plattner Institute, Universität Potsdam, Potsdam, 14482, Germany., Broer L; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, 3015 CN, Netherlands., Campbell H; Centre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, EH8 9AG, Scotland., Chanock S; Division of Cancer Epidemiology & Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA., Chee ML; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore, 169856, Singapore., Chen G; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, 20892-5635, USA., Chen YI; Division of Genomic Outcomes, Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, California, 90502, USA., Chen Z; Nuffield Department of Population Health, University of Oxford, Oxford, OX3 7LF, UK., Chiu YF; Institute of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan, Taiwan., Cocca M; Institute for Maternal and Child Health - IRCCS Burlo Garofolo, Trieste, 34137, Italy., Collins FS; National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, 20892, USA., Concas MP; Institute for Maternal and Child Health - IRCCS Burlo Garofolo, Trieste, 34137, Italy., Corley J; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, EH8 9JZ, UK.; Department of Psychology, University of Edinburgh, 7 George Square, Edinburgh, EH8 9JZ, UK., Cugliari G; Italian Institute for Genomic Medicine (IIGM) and Dept. Medical Sciences, University of Turin, Italy, Turin, 10126, Italy., van Dam RM; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore, 117549, Singapore.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 119228, SG, Singapore.; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, 02115, USA., Damulina A; Clinical Division of Neurogeriatrics, Department of Neurology, Medical University of Graz, Graz, 8036, Austria., Daneshpour MS; Cellular and Molecular Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, 19839-63113, Iran., Day FR; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, CB2 0QQ, UK., Delgado GE; Vth Department of Medicine (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim, Heidelberg University, Mannheim, 68167, Germany., Dhana K; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015 CN, Netherlands.; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, 02115, USA.; Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois, USA., Doney ASF; MEMO Research, Molecular and Clinical Medicine, University of Dundee, Dundee, DD19SY, UK., Dörr M; Department of Internal Medicine B, University Medicine Greifswald, Greifswald, 17475, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, 17475, Germany., Doumatey AP; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, 20892-5635, USA., Dzimiri N; Department of Genetics, King Faisal Specialist Hospital and Research Center, Riyadh, KSA, 12713, Saudi Arabia., Ebenesersdóttir SS; deCODE genetics/Amgen Inc., Reykjavik 101, Iceland.; Department of Anthropology, University of Iceland, Reykjavik, 101, Iceland., Elliott J; Department of Epidemiology and Biostatistics, Imperial College London, London, W2 1PG, UK., Elliott P; Department of Epidemiology and Biostatistics, Imperial College London, London, W2 1PG, UK.; MRC-PHE Centre for Environment and Health, Imperial College London, London, W2 1PG, UK.; National Institute for Health Research Imperial Biomedical Research Centre, Imperial College Healthcare NHS Trust and Imperial College London, London, UK.; UK Dementia Research Institute (UK DRI) at Imperial College London, London, UK.; Health Data Research UK - London, London, England., Ewert R; Department of Internal Medicine B, University Medicine Greifswald, Greifswald, 17475, Germany., Felix JF; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015 CN, Netherlands.; The Generation R Study Group, Erasmus University Medical Center, Rotterdam, 3015 CN, The Netherlands.; Department of Pediatrics, Erasmus University Medical Center, Rotterdam, 3015CN, The Netherlands., Fischer K; Estonian Genome Center, University of Tartu, University of Tartu, Tartu, 51010, Estonia., Freedman BI; Section on Nephrology, Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC, 27101, US., Girotto G; Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy.; Medical Genetics, Institute for Maternal and Child Health - IRCCS Burlo Garofolo, Trieste, Italy., Goel A; Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, OX3 9DU, UK., Gögele M; Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lübeck, Bolzano, 39100, Italy., Goodarzi MO; Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, 90048, USA., Graff M; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, 27514, USA., Granot-Hershkovitz E; Braun School of Public Health, Hebrew University-Hadassah Medical Center, Jerusalem, Israel., Grodstein F; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, 02115, USA., Guarrera S; Italian Institute for Genomic Medicine (IIGM) and Dept. Medical Sciences, University of Turin, Italy, Turin, 10126, Italy., Gudbjartsson DF; deCODE genetics/Amgen Inc., Reykjavik 101, Iceland.; School of Engineering and Natural Sciences, University of Iceland, Reykjavik, 101, Iceland., Guity K; Cellular and Molecular Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, 19839-63113, Iran., Gunnarsson B; deCODE genetics/Amgen Inc., Reykjavik 101, Iceland., Guo Y; Chinese Academy of Medical Sciences, Beijing, 100730, China., Hagenaars SP; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, EH8 9JZ, UK.; Department of Psychology, University of Edinburgh, 7 George Square, Edinburgh, EH8 9JZ, UK.; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, SE5 8AF, UK., Haiman CA; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, 90089, USA., Halevy A; Braun School of Public Health, Hebrew University-Hadassah Medical Center, Jerusalem, Israel., Harris TB; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Baltimore City, Maryland, 21224, USA., Hedayati M; Cellular and Molecular Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, 19839-63113, Iran., van Heel DA; Blizard Institute, Queen Mary University of London, London, E1 2AT, UK., Hirata M; Laboratory of Genome Technology, Institute of Medical Science, The University of Tokyo, Tokyo, 108-8639, Japan., Höfer I; Laboratory of Clinical Chemistry and Hematology, Division Laboratories and Pharmacy, University Medical Center Utrecht, University of Utrecht, Utrecht, Utrecht, 3584 CX, Netherlands., Hsiung CA; Institute of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan, Taiwan., Huang J; Shanghai Institute of Hematology, State Key Laboratory Of Medical Genomics, Rui-jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China, 200025, China., Hung YJ; Division of Endocrine and Metabolism, Tri-Service General Hospital Songshan branch, Taipei, Taiwan, Taiwan.; School of Medicine, National Defense Medical Center, Taipei, Taiwan, Taiwan., Ikram MA; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015 CN, Netherlands., Jagadeesan A; deCODE genetics/Amgen Inc., Reykjavik 101, Iceland.; Department of Anthropology, University of Iceland, Reykjavik, 101, Iceland., Jousilahti P; Unit of Public Health Promotion, National Institute for Health and Welfare, Helsinki, Finland., Kamatani Y; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, 230-0045, Japan.; Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, 606-8507, Japan., Kanai M; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Osaka, 565-0871, Japan.; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, 230-0045, Japan.; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, 02115, USA., Kerrison ND; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, CB2 0QQ, UK., Kessler T; Deutsches Herzzentrum München, Klinik für Herz- und Kreislauferkrankungen, Technische Universität München, Munich, 80636, Germany., Khaw KT; Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB2 0SR, UK., Khor CC; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore, 169856, Singapore.; Human Genetics, Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore, Singapore, 138672, Singapore., de Kleijn DPV; Department of Vascular Surgery, Division of Surgical Specialties, University Medical Center Utrecht, University of Utrecht, Utrecht, Utrecht, 3584 CX, Netherlands., Koh WP; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore, 117549, Singapore.; Health Services and Systems Research, Duke-NUS Medical School, Singapore, Singapore, 169857., Kolcic I; Centre for Global Health, Faculty of Medicine, University of Split, Split, Croatia., Kraft P; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, 02115, USA., Krämer BK; Vth Department of Medicine (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim, Heidelberg University, Mannheim, 68167, Germany., Kutalik Z; Center for Primary Care and Public Health (Unisanté), University of Lausanne, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, 1015, Switzerland., Kuusisto J; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio, Finland.; Kuopio University Hospital, Kuopio, Finland., Langenberg C; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, CB2 0QQ, UK., Launer LJ; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Baltimore City, Maryland, 21224, USA., Lawlor DA; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, BS8 2BN, UK.; Bristol NIHR Biomedical Research Centre, Bristol, BS8 2BN, UK.; Population Health Science, Bristol Medical School, Bristol, BS8 2BY, UK., Lee IT; Division of Endocrinology and Metabolism, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan, Taiwan.; School of Medicine, National Yang-Ming University, Taipei, Taiwan, Taipei, 112, Taiwan.; School of Medicine, Chung Shan Medical University, Taichung, Taiwan, Taichung City, 402, Taiwan., Lee WJ; Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan, Taiwan., Lerch MM; Department of Internal Medicine A, University Medicine Greifswald, Greifswald, 17475, Germany., Li L; Department of Epidemiology and Biostatistics, Peking University Health Science Centre, Peking University, Beijing, 100191, China., Liu J; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 119228, SG, Singapore.; Human Genetics, Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore, Singapore, 138672, Singapore., Loh M; Department of Epidemiology and Biostatistics, Imperial College London, London, W2 1PG, UK.; Translational Laboratory in Genetic Medicine, Agency for Science, Technology and Research, Singapore (A*STAR), Singapore, 138648, Singapore.; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore, 117596, Singapore., London SJ; National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, Durham, NC, 27709, USA., Loomis S; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, 21205, USA., Lu Y; The Charles Bronfman Institute for Personalized Medicine, Ichan School of Medicine at Mount Sinai, New York, NY, 10029, USA., Luan J; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, CB2 0QQ, UK., Mägi R; Estonian Genome Center, University of Tartu, University of Tartu, Tartu, 51010, Estonia., Manichaikul AW; Center for Public Health Genomics, University of Virginia School of Medicine, Charlottesville, VA, 22908, USA., Manunta P; Genomics of Renal Diseases and Hypertension Unit, IRCCS San Raffaele Scientific Institute, Università Vita Salute San Raffaele, Milano, 20132, Italy., Másson G; deCODE genetics/Amgen Inc., Reykjavik 101, Iceland., Matoba N; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, 230-0045, Japan., Mei XW; Nuffield Department of Population Health, University of Oxford, Oxford, OX3 7LF, UK., Meisinger C; Helmholtz Zentrum München, Independent Research Group Clinical Epidemiology, Neuherberg, 85764, Germany., Meitinger T; Institute of Human Genetics, Helmholtz Zentrum Muenchen, Neuherberg, 85764, Germany.; Institute of Human Genetics, Technical University of Munich, Munich, 81675, Germany.; DZHK (German Center for Cardiovascular Research), partner site Munich Heart Alliance, Munich, 80802, Germany., Mezzavilla M; Medical Genetics, Institute for Maternal and Child Health - IRCCS Burlo Garofolo, Trieste, Italy., Milani L; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, 51010, Estonia., Millwood IY; Nuffield Department of Population Health, University of Oxford, Oxford, OX3 7LF, UK., Momozawa Y; Laboratory for Genotyping Development, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, 230-0045, Japan., Moore A; Division of Cancer Epidemiology & Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA., Morange PE; Laboratory of Haematology, La Timone Hospital, Marseille, France.; INSERM UMR_S 1263, Center for CardioVascular and Nutrition research (C2VN), Aix-Marseille University, Marseille, France., Moreno-Macías H; Departamento de Economía, Universidad Autónoma Metropolitana, Mexico, 09340, México., Mori TA; Medical School, The University of Western Australia, Perth, Western Australia/Australia, 6009, Australia., Morrison AC; The University of Texas Health Science Center at Houston, School of Public Health, Department of Epidemiology, Human Genetics and Environmental Sciences, Houston, Texas, 77030, USA., Muka T; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015 CN, Netherlands.; Institute of Social and Preventive Medicine (ISPM), University of Bern, Bern, Switzerland., Murakami Y; Division of Molecular Pathology, Institute of Medical Science, The University of Tokyo, Tokyo, 108-8639, Japan., Murray AD; The Institute of Medical Sciences, Aberdeen Biomedical Imaging Centre, University of Aberdeen, Aberdeen, AB25 2ZD, UK., de Mutsert R; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, 2333 ZA, The Netherlands., Mychaleckyj JC; Center for Public Health Genomics, University of Virginia School of Medicine, Charlottesville, VA, 22908, USA., Nalls MA; Laboratory of Neurogenetics, Bethesda, MD, 20892, USA.; Data Tecnica International LLC, Glen Echo, MD, 20812, USA., Nauck M; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, 17475, Germany.; Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, 17475, Germany., Neville MJ; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Headington, Oxford, OX3 7LJ, UK.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, UK., Nolte IM; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, 9700 RB, The Netherlands., Ong KK; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, CB2 0QQ, UK.; Department of Paediatrics, University of Cambridge School of Clinical Medicine, Cambridge, CB2 0QQ, UK., Orozco L; Instituto Nacional de Medicina Genómica, Mexico, 14610, México., Padmanabhan S; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, G12 8TA, UK., Pálsson G; deCODE genetics/Amgen Inc., Reykjavik 101, Iceland., Pankow JS; Division of Epidemiology & Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, 55454, USA., Pattaro C; Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lübeck, Bolzano, 39100, Italy., Pattie A; Department of Psychology, University of Edinburgh, 7 George Square, Edinburgh, EH8 9JZ, UK., Polasek O; Centre for Global Health, Faculty of Medicine, University of Split, Split, Croatia.; Gen-info Ltd, Zagreb, Croatia, Zagreb, Select a Province, 10000, Croatia., Poulter N; International Centre for Circulatory Health, Imperial College London, London, W2 1PG, UK.; Imperial Clinical Trials Unit, Imperial College London, London, London, W12 7TA, UK., Pramstaller PP; Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lübeck, Bolzano, 39100, Italy., Quintana-Murci L; Human Evolutionary Genetics Unit, Institut Pasteur, Paris, 75015, France.; Centre National de la Recherche Scientifique (CNRS) UMR2000, Paris, 75015, France.; Center of Bioinformatics, Biostatistics and Integrative Biology, Institut Pasteur, Paris, 75015, France., Räikkönen K; Department of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, University of Helsinki, Helsinki, 00014, Finland., Ralhan S; Hero Heart Institute and Dyanand Medical College and Hospital, Ludhiana, Punjab, India., Rao DC; Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri, USA., van Rheenen W; Department of Neurology, Brain Centre Rudolf Magnus, University Medical Centre Utrecht, Utrecht University, Utrecht, 3584 CX, The Netherlands., Rich SS; Center for Public Health Genomics, University of Virginia School of Medicine, Charlottesville, VA, 22908, USA., Ridker PM; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, 02215, USA.; Harvard Medical School, Boston, MA, 02115, USA., Rietveld CA; Department of Applied Economics, Erasmus School of Economics, Erasmus University Rotterdam, Rotterdam, 3062 PA, The Netherlands.; Erasmus University Rotterdam Institute for Behavior and Biology, Erasmus University Rotterdam, Rotterdam, 3062 PA, The Netherlands., Robino A; Institute for Maternal and Child Health - IRCCS Burlo Garofolo, Trieste, 34137, Italy., van Rooij FJA; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015 CN, Netherlands., Ruggiero D; Institute of Genetics and Biophysics A. Buzzati-Traverso - CNR, Naples, 80131, Italy.; IRCCS Neuromed, Pozzilli (IS), 86077, Italy., Saba Y; Gottfried Schatz Research Center (for Cell Signaling, Metabolism and Aging), Division of Molecular Biology and Biochemistry, Medical University of Graz, 8010, Graz, Austria., Sabanayagam C; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore, 169856, Singapore.; Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore, 169857, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore, 119228, SG, Singapore., Sabater-Lleal M; Cardiovascular Medicine Unit, Department of Medicine Solna, Centre for Molecular Medicine, Karolinska Institutet, Stockholm, 171 76, Sweden.; Unit of Genomics of Complex Diseases, Institut de Recerca Hospital de la Santa Creu i Sant Pau, IIB-Sant Pau, Barcelona, Spain., Sala CF; San Raffaele Research Institute, Milano, Italy., Salomaa V; Department of Public Health Solutions, National Institute for Health and Welfare, Helsinki, FI-00271, Finland., Sandow K; Division of Genomic Outcomes, Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, California, 90502, USA., Schmidt H; Gottfried Schatz Research Center (for Cell Signaling, Metabolism and Aging), Division of Molecular Biology and Biochemistry, Medical University of Graz, 8010, Graz, Austria., Scott LJ; Department of Biostatistics, and Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, 48109, USA., Scott WR; Department of Epidemiology and Biostatistics, Imperial College London, London, W2 1PG, UK., Sedaghati-Khayat B; Cellular and Molecular Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, 19839-63113, Iran., Sennblad B; Cardiovascular Medicine Unit, Department of Medicine Solna, Centre for Molecular Medicine, Karolinska Institutet, Stockholm, 171 76, Sweden.; Dept of Cell and Molecular Biology, National Bioinformatics Infrastructure Sweden, Science for Life Laboratory, Uppsala University, Uppsala, SE-752 37, Uppsala, Sweden., van Setten J; Department of Cardiology, Division Heart & Lungs, University Medical Center Utrecht, University of Utrecht, Utrecht, Utrecht, 3485 CX, Netherlands., Sever PJ; International Centre for Circulatory Health, Imperial College London, London, W2 1PG, UK., Sheu WH; School of Medicine, National Defense Medical Center, Taipei, Taiwan, Taiwan.; Division of Endocrinology and Metabolism, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan, Taiwan.; School of Medicine, National Yang-Ming University, Taipei, Taiwan, Taiwan.; Institute of Medical Technology, National Chung-Hsing University, Taichung, Taiwan, Taiwan., Shi Y; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore, 169856, Singapore., Shrestha S; Genomic Research on Complex diseases (GRC Group), CSIR-Centre for Cellular and Molecular Biology, Hyderabad, Telangana, 500007, India.; School of Basic and Applied Sciences, Dayananda Sagar University, Bangalore, Karnataka, 560078, India., Shukla SR; Diabetes Unit, KEM Hospital and Research Centre, Pune, Maharashtra, 411101, India.; Symbiosis Statistical Institute, Symbiosis International University, Pune, Maharashtra, 411007, India., Sigurdsson JK; deCODE genetics/Amgen Inc., Reykjavik 101, Iceland., Sikka TT; Estonian Genome Center, University of Tartu, University of Tartu, Tartu, 51010, Estonia., Singh JR; Panjab University, Chandigarh, India., Smith BH; Division of Population Health Sciences, Ninewells Hospital and Medical School, University of Dundee, Dundee, DD1 9SY, UK., Stančáková A; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio, Finland., Stanton A; RCSI Molecular & Cellular Therapeutics (MCT), Royal College of Surgeons in Ireland, RCSI Education & Research Centre, Beaumont Hospital, Dublin 9, Ireland., Starr JM; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, EH8 9JZ, UK.; Alzheimer Scotland Dementia Research Centre, University of Edinburgh, Edinburgh, EH8 9JZ, Scotland., Stefansdottir L; deCODE genetics/Amgen Inc., Reykjavik 101, Iceland., Straker L; School of Physiotherapy and Exercise Science, Faculty of Health Sciences, Curtin University, Perth, Western Australia/Australia, 6102, Australia., Sulem P; deCODE genetics/Amgen Inc., Reykjavik 101, Iceland., Sveinbjornsson G; deCODE genetics/Amgen Inc., Reykjavik 101, Iceland., Swertz MA; Department of Genetics, University Medical Centre Groningen, University of Groningen, Groningen, the Netherlands, Groningen, Groningen, 9700 RB, The Netherlands., Taylor AM; Department of Psychology, University of Edinburgh, 7 George Square, Edinburgh, EH8 9JZ, UK., Taylor KD; Division of Genomic Outcomes, Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, California, 90502, USA., Terzikhan N; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015 CN, Netherlands.; Department of Respiratory Medicine, Ghent University Hospital, Ghent, 9000, Belgium., Tham YC; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore, 169856, Singapore.; Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore, 169857, Singapore., Thorleifsson G; deCODE genetics/Amgen Inc., Reykjavik 101, Iceland., Thorsteinsdottir U; deCODE genetics/Amgen Inc., Reykjavik 101, Iceland.; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, 101, Iceland., Tillander A; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, 17177, Sweden., Tracy RP; Department of Pathology, University of Vermont, Colchester, VT, 05446, USA., Tusié-Luna T; Departamento de Medicina Genómica y Toxicología Ambiental, Instituto de Investigaciones Biomédicas, UNAM, Mexico, 04510, México.; Unidad De Biología Molecular y Medicina Genómica, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico, 14080, México., Tzoulaki I; Department of Epidemiology and Biostatistics, Imperial College London, London, W2 1PG, UK.; MRC-PHE Centre for Environment and Health, Imperial College London, London, W2 1PG, UK.; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, 45110, Greece., Vaccargiu S; Institute of Genetic and Biomedical Research - Support Unity, National Research Council of Italy, Rome, Italy., Vangipurapu J; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio, Finland., Veldink JH; Department of Neurology, Brain Centre Rudolf Magnus, University Medical Centre Utrecht, Utrecht University, Utrecht, 3584 CX, The Netherlands., Vitart V; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XU, Scotland., Völker U; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, 17475, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, 17475, Germany., Vuoksimaa E; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, FI-00014, Finland., Wakil SM; Department of Genetics, King Faisal Specialist Hospital and Research Center, Riyadh, KSA, 12713, Saudi Arabia., Waldenberger M; Research Unit of Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, 85764, Germany., Wander GS; Department of Cardiology, Hero DMC Heart Institute, Dayanand Medical College & Hospital, Ludhiana, Punjab, 141001, India., Wang YX; Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Science Key Lab, Beijing, China, 100005, China., Wareham NJ; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, CB2 0QQ, UK., Wild S; Centre for Population Health Sciences, Usher Institute of Population Health and Informatics, University of Edinburgh, Edinburgh, EH8 9AG, Scotland., Yajnik CS; Diabetes Unit, K.E.M. Hospital Research Centre, Pune, MAH, 411011, India., Yuan JM; Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Zeng L; Deutsches Herzzentrum München, Klinik für Herz- und Kreislauferkrankungen, Technische Universität München, Munich, 80636, Germany., Zhang L; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore, 169856, Singapore., Zhou J; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, 20892-5635, USA., Amin N; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015 CN, Netherlands., Asselbergs FW; Department of Cardiology, Division Heart & Lungs, University Medical Center Utrecht, University of Utrecht, Utrecht, Utrecht, 3584 CX, Netherlands.; Institute of Cardiovascular Science, Faculty of Population Health Sciences, University College London, London, WC1E 6DD, UK.; Durrer Center for Cardiovascular Research, Netherlands Heart Institute, Utrecht, Netherlands.; Farr Institute of Health Informatics Research and Institute of Health Informatics, University College London, London, UK., Bakker SJL; Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen, 9713GZ, The Netherlands., Becker DM; Department of Medicine, GeneSTAR Research Program, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA., Lehne B; Department of Epidemiology and Biostatistics, Imperial College London, London, W2 1PG, UK., Bennett DA; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, 60612, USA.; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, 60612, USA., van den Berg LH; Department of Neurology, Brain Centre Rudolf Magnus, University Medical Centre Utrecht, Utrecht University, Utrecht, 3584 CX, The Netherlands., Berndt SI; Division of Cancer Epidemiology & Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA., Bharadwaj D; Systems Genomics Laboratory, School of Biotechnology, Jawaharlal Nehru University, New Delhi, 110067, India., Bielak LF; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, 48109, USA., Bochud M; Center for Primary Care and Public Health (Unisanté), University of Lausanne, Lausanne, Switzerland., Boehnke M; Department of Biostatistics, and Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, 48109, USA., Bouchard C; Pennington Biomedical Research Center, Baton Rouge, Louisiane, 70808, USA., Bradfield JP; Center for Applied Genomics, Division of Human Genetics, Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.; Quantinuum Research LLC, San Diego, CA, 92101, USA., Brody JA; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, 98101, USA., Campbell A; Centre for Genomic & Experimental Medicine, Institute of Genetics & Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK., Carmi S; Braun School of Public Health, Hebrew University-Hadassah Medical Center, Jerusalem, Israel., Caulfield MJ; NIHR Barts Cardiovascular Biomedical Research Centre, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK.; Department of Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK., Cesarini D; Center for Experimental Social Science, Department of Economics, New York University, New York, New York, 10012, USA.; Research Institute for Industrial Economics (IFN), Stockholm, 102 15, Sweden., Chambers JC; Department of Epidemiology and Biostatistics, Imperial College London, London, W2 1PG, UK.; Department of Cardiology, Ealing Hospital, Middlesex, Middlesex, UB1 3HW, UK.; MRC-PHE Centre for Environment and Health, Imperial College London, London, W2 1PG, UK.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, 308232, Singapore.; Imperial College Healthcare NHS Trust, London, London, W12 0HS, UK., Chandak GR; Genomic Research on Complex diseases (GRC Group), CSIR-Centre for Cellular and Molecular Biology, Hyderabad, Telangana, 500007, India., Cheng CY; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore, 169856, Singapore.; Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore, 169857, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore, 119228, SG, Singapore., Ciullo M; Institute of Genetics and Biophysics A. Buzzati-Traverso - CNR, Naples, 80131, Italy.; IRCCS Neuromed, Pozzilli (IS), 86077, Italy., Cornelis M; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA., Cusi D; Department of Health Sciences, University of Milano, Milano, 20139, Italy.; Institute of Biomedical Technologies Milano, National Research Council of Italy (CNR), Segrate (Milano), 20090, Italy.; Bio4Dreams Scientific Unit, Bio4Dreams SRL, Bio4Dreams - business nursery for life sciences, Milano, 20121, Italy., Smith GD; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, BS8 2BN, UK.; Population Health Science, Bristol Medical School, Bristol, BS8 2BY, UK., Deary IJ; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, EH8 9JZ, UK.; Department of Psychology, University of Edinburgh, 7 George Square, Edinburgh, EH8 9JZ, UK., Dorajoo R; Human Genetics, Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore, Singapore, 138672, Singapore., van Duijn CM; Nuffield Department of Population Health, University of Oxford, Oxford, OX3 7LF, UK.; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015 CN, Netherlands., Ellinghaus D; Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, 24105, Kiel, Germany., Erdmann J; Institute for Cardiogenetics, University of Lübeck, Lübeck, 23562, Germany., Eriksson JG; Department of General Practice and Primary health Care, University of Helsinki, Tukholmankatu 8 B, Helsinki, 00014, Finland.; National Institute for Health and Welfare, Helsinki, Finland.; Unit of General Practice, Helsinki University Central Hospital, Helsinki, Finland.; Folkhälsan Research Centre, Helsinki, Finland.; Vasa Central Hospital, Vaasa, Finland., Evangelou E; Department of Epidemiology and Biostatistics, Imperial College London, London, W2 1PG, UK.; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, 45110, Greece., Evans MK; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Baltimore City, Maryland, 21224, USA., Faul JD; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, 48014, USA., Feenstra B; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, DK-2300, Denmark., Feitosa M; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, Saint Louis, MO, 63110-1093, USA., Foisy S; Montreal Heart Institute, Montreal, QC, Canada., Franke A; Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, 24105, Kiel, Germany., Friedlander Y; Braun School of Public Health, Hebrew University-Hadassah Medical Center, Jerusalem, Israel., Gasparini P; Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy.; Medical Genetics, Institute for Maternal and Child Health - IRCCS Burlo Garofolo, Trieste, Italy., Gieger C; Research Unit of Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, 85764, Germany.; German Center for Diabetes Research (DZD), München-Neuherberg, Germany., Gonzalez C; Centro de Estudios en Diabetes, Unidad de Investigacion en Diabetes y Riesgo Cardiovascular, Centro de Investigacion en Salud Poblacional, Instituto Nacional de Salud Publica, Cuernavaca, 01120, México., Goyette P; Montreal Heart Institute, Montreal, QC, Canada., Grant SFA; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.; Center for Applied Genomics, Division of Human Genetics, Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Griffiths LR; Genomics Research Centre, School of Biomedical Sciences, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, 4059, Australia., Groop L; Finnish Institute for Molecular Medicine, University of Helsinki, Helsinki, Finland.; Department of Clinical Sciences, Diabetes and Endocrinology, Lund University Diabetes Centre, Lund University, Skåne University Hospital, Malmö, 20502, Sweden., Gudnason V; Icelandic Heart Association, Kopavogur, 201, Iceland.; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, 101, Iceland., Gyllensten U; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, 75108, Uppsala, Sweden., Hakonarson H; Center for Applied Genomics, Division of Human Genetics, Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Hamsten A; Cardiovascular Medicine Unit, Department of Medicine Solna, Centre for Molecular Medicine, Stockholm, 171 76, Sweden., van der Harst P; University of Groningen, University Medical Center Groningen, Department of Cardiology, Ther Netherlands, Groningen, 9713 GZ, the Netherlands., Heng CK; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Khoo Teck Puat - National University Children's Medical Institute, National University Health System, Singapore, Singapore., Hicks AA; Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lübeck, Bolzano, 39100, Italy., Hochner H; Braun School of Public Health, Hebrew University-Hadassah Medical Center, Jerusalem, Israel., Huikuri H; Research Unit of Internal Medicine, Medical Research Center Oulu, University of Oulu and Oulu University Hospital, Oulu, 90014, Finland., Hunt SC; Department of Genetic Medicine, Weill Cornell Medicine Qatar, Doha, Qatar.; Division of Epidemiology, Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, Utah, 84108, USA., Jaddoe VWV; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015 CN, Netherlands.; The Generation R Study Group, Erasmus University Medical Center, Rotterdam, 3015 CN, The Netherlands.; Department of Pediatrics, Erasmus University Medical Center, Rotterdam, 3015CN, The Netherlands., De Jager PL; Center for Translational & Computational Neuroimmunology, Department of Neurology, Columbia University Medical Center, 650 West 168th street, PH19-311, Newyork, NY, 10032, USA.; Cell Circuits Program, Broad Institute, Cambridge, MA, 02142, USA., Johannesson M; Department of Economics, Stockholm School of Economics, Stockholm, SE-113 83, Sweden., Johansson Å; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, 75108, Uppsala, Sweden., Jonas JB; Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Science Key Lab, Beijing, China, 100005, China.; Department of Ophthalmology, Medical Faculty Mannheim of the Ruprecht-Karls-University of Heidelberg, Mannheim, 698167, Germany., Jukema JW; Department of Cardiology, Leiden University Medical Center, Leiden, 2300 RC, the Netherlands., Junttila J; Research Unit of Internal Medicine, Medical Research Center Oulu, University of Oulu and Oulu University Hospital, Oulu, 90014, Finland., Kaprio J; Finnish Institute for Molecular Medicine, University of Helsinki, Helsinki, Finland.; Department of Public Health, University of Helsinki, Helsinki, FI-00014, Finland., Kardia SLR; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, 48109, USA., Karpe F; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Headington, Oxford, OX3 7LJ, UK.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, Oxford, OX3 9DU, UK., Kumari M; Institute for Social and Economic Research, University of Essex, Colchester, CO4 3SQ, UK., Laakso M; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio, Finland.; Kuopio University Hospital, Kuopio, Finland., van der Laan SW; Laboratory of Clinical Chemistry and Hematology, Division Laboratories and Pharmacy, University Medical Center Utrecht, University of Utrecht, Utrecht, 3584 CX, Netherlands., Lahti J; Department of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, University of Helsinki, Helsinki, 00014, Finland.; Helsinki Collegium for Advanced Studies, University of Helsinki, University of Helsinki, Helsinki, 00014, Finland., Laudes M; University Hospital Schleswig-Holstein (UKSH), Campus Kiel, Kiel, 24105, Germany., Lea RA; Genomics Research Centre, School of Biomedical Sciences, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, 4059, Australia., Lieb W; Institute of Epidemiology and PopGen Biobank, University of Kiel, Kiel, Schleswig Holstein, 24105, Germany., Lumley T; Department of Statistics, University of Auckland, Auckland, New Zealand., Martin NG; QIMR Berghofer Institute of Medical Research, Brisbane, Australia., März W; Vth Department of Medicine (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim, Heidelberg University, Mannheim, 68167, Germany.; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria.; Synlab Academy, Synlab Holding Deutschland GmbH, Mannheim, Germany., Matullo G; Italian Institute for Genomic Medicine (IIGM) and Dept. Medical Sciences, University of Turin, Italy, Turin, 10126, Italy., McCarthy MI; Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Headington, Oxford, OX3 7LJ, UK.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, Oxford, OX3 9DU, UK., Medland SE; QIMR Berghofer Institute of Medical Research, Brisbane, Australia., Merriman TR; Department of Biochemistry, University of Otago, Dunedin, 9054, New Zealand., Metspalu A; Estonian Genome Center, University of Tartu, University of Tartu, Tartu, 51010, Estonia., Meyer BF; Department of Genetics, King Faisal Specialist Hospital and Research Centre, Riyadh, 11211, Saudi Arabia., Mohlke KL; Department of Genetics, University of North Carolina, Chapel Hill, NC, 27599, USA., Montgomery GW; QIMR Berghofer Institute of Medical Research, Brisbane, Australia.; Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, 4072, Australia., Mook-Kanamori D; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, 2333 ZA, The Netherlands.; Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, 2333 ZA, The Netherlands., Munroe PB; NIHR Barts Cardiovascular Biomedical Research Centre, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK.; Department of Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK., North KE; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, 27514, USA., Nyholt DR; QIMR Berghofer Institute of Medical Research, Brisbane, Australia.; School of Biomedical Sciences, Institute of Health and Biomedical Innovation, Queensland University of Technology, Kelvin Grove, QLD, 4059, Australia., O'connell JR; Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland, School of Medicine, Baltimore, MD, 21201, USA.; Program for Personalized and Genomic Medicine, Department of Medicine, University of Maryland, School of Medicine, Baltimore, MD, 21201, USA., Ober C; Department of Human Genetics, University of Chicago, Chicago, IL, 60637, USA., Oldehinkel AJ; Department of Psychiatry, Interdisciplinary Center Psychopathology and Emotion Regulation, University of Groningen, University Medical Center Groningen, Groningen, 9700 RB, The Netherlands., Palmas W; Department of Medicine, Columbia University Medical Center, New York, New York, USA., Palmer C; Pat Macpherson Centre for Pharmacogenetics and Pharmacogenomics, The School of Medicine, University of Dundee, Dundee, DD1 9SY, UK., Pasterkamp GG; Laboratory of Clinical Chemistry and Hematology, Division Laboratories and Pharmacy, University Medical Center Utrecht, University of Utrecht, Utrecht, Utrecht, 3584 CX, Netherlands., Patin E; Human Evolutionary Genetics Unit, Institut Pasteur, Paris, 75015, France.; Centre National de la Recherche Scientifique (CNRS) UMR2000, Paris, 75015, France.; 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المصدر: Nature communications [Nat Commun] 2019 Oct 31; Vol. 10 (1), pp. 4957. Date of Electronic Publication: 2019 Oct 31.

نوع المنشور: Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Cognition* , Consanguinity* , Health Status* , Risk-Taking*, Body Size/*genetics , Fertility/*genetics , Inbreeding Depression/*genetics, Alleles ; Haplotypes ; Homozygote ; Humans