المؤلفون: Jimenez SA; Department of Dermatology and Cutaneous Biology, Jefferson Institute of Molecular Medicine and Scleroderma Center, Thomas Jefferson University, Philadelphia 19107, USA., Piera-Velazquez S; Department of Dermatology and Cutaneous Biology, Jefferson Institute of Molecular Medicine and Scleroderma Center, Thomas Jefferson University, Philadelphia 19107, USA.

المصدر: Current rheumatology reviews [Curr Rheumatol Rev] 2024; Vol. 20 (4), pp. 388-404.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Bentham Science Publishers Country of Publication: United Arab Emirates NLM ID: 101261938 Publication Model: Print Cited Medium: Internet ISSN: 1875-6360 (Electronic) Linking ISSN: 15733971 NLM ISO Abbreviation: Curr Rheumatol Rev Subsets: MEDLINE

مواضيع طبية MeSH: Scleroderma, Systemic*/pathology , Cell Transdifferentiation* , Fibrosis*, Humans ; Myofibroblasts/pathology

المؤلفون: Wermuth PJ; Jefferson Institute of Molecular Medicine and Scleroderma Center, Thomas Jefferson University, Philadelphia, PA, 19107, USA. peter.wermuth@jefferson.edu., Mendoza FA; Jefferson Institute of Molecular Medicine and Scleroderma Center, Thomas Jefferson University, Philadelphia, PA, 19107, USA.; Division of Rheumatology, Department of Medicine, Thomas Jefferson University, Philadelphia, PA, 19107, USA., Jimenez SA; Jefferson Institute of Molecular Medicine and Scleroderma Center, Thomas Jefferson University, Philadelphia, PA, 19107, USA.

المصدر: Laboratory investigation; a journal of technical methods and pathology [Lab Invest] 2019 Apr; Vol. 99 (4), pp. 470-482. Date of Electronic Publication: 2018 Nov 23.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Elsevier Inc Country of Publication: United States NLM ID: 0376617 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1530-0307 (Electronic) Linking ISSN: 00236837 NLM ISO Abbreviation: Lab Invest Subsets: MEDLINE

مواضيع طبية MeSH: NADPH Oxidase 4*/genetics , NADPH Oxidase 4*/metabolism , Transforming Growth Factor beta1*/metabolism , Transforming Growth Factor beta1*/pharmacology, Fibrosis/*metabolism, Animals ; DNA Damage ; Gene Knockout Techniques ; Hydroxyproline ; Lung/chemistry ; Lung/pathology ; Mice ; Mice, Inbred C57BL ; Oxidative Stress/drug effects ; Oxidative Stress/genetics ; Scleroderma, Systemic ; Skin/chemistry ; Skin/pathology

المؤلفون: Wermuth PJ; Jefferson Institute of Molecular Medicine, Thomas Jefferson University, Philadelphia, PA, USA., Carney KR; Jefferson Institute of Molecular Medicine, Thomas Jefferson University, Philadelphia, PA, USA., Mendoza FA; Rheumatology Division, Department of Medicine, Thomas Jefferson University, Philadelphia, PA, USA., Piera-Velazquez S; Jefferson Institute of Molecular Medicine, Thomas Jefferson University, Philadelphia, PA, USA., Jimenez SA; Jefferson Institute of Molecular Medicine, Thomas Jefferson University, Philadelphia, PA, USA.

المصدر: Laboratory investigation; a journal of technical methods and pathology [Lab Invest] 2017 Jul; Vol. 97 (7), pp. 806-818. Date of Electronic Publication: 2017 Mar 27.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Elsevier Inc Country of Publication: United States NLM ID: 0376617 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1530-0307 (Electronic) Linking ISSN: 00236837 NLM ISO Abbreviation: Lab Invest Subsets: MEDLINE

مواضيع طبية MeSH: Endothelial Cells/*metabolism , Fibrosis/*metabolism , Signal Transduction/*physiology , Transforming Growth Factor beta/*metabolism, Animals ; Female ; Hydroxyproline ; Immunohistochemistry ; Lung/chemistry ; Male ; Mice ; Mice, Transgenic ; Microscopy, Confocal ; Organ Specificity ; Tamoxifen ; Transforming Growth Factor beta/genetics

المؤلفون: Rosenbloom J; The Joan and Joel Rosenbloom Center for Fibrotic Diseases and The Jefferson Institute of Molecular Medicine, Thomas Jefferson University, Philadelphia, PA, USA., Macarak E; The Joan and Joel Rosenbloom Center for Fibrotic Diseases and The Jefferson Institute of Molecular Medicine, Thomas Jefferson University, Philadelphia, PA, USA., Piera-Velazquez S; The Joan and Joel Rosenbloom Center for Fibrotic Diseases and The Jefferson Institute of Molecular Medicine, Thomas Jefferson University, Philadelphia, PA, USA., Jimenez SA; The Joan and Joel Rosenbloom Center for Fibrotic Diseases and The Jefferson Institute of Molecular Medicine, Thomas Jefferson University, Philadelphia, PA, USA. sergio.jimenez@jefferson.edu.

المصدر: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2017; Vol. 1627, pp. 1-23.

نوع المنشور: Journal Article; Review; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Humana Press Country of Publication: United States NLM ID: 9214969 Publication Model: Print Cited Medium: Internet ISSN: 1940-6029 (Electronic) Linking ISSN: 10643745 NLM ISO Abbreviation: Methods Mol Biol Subsets: MEDLINE

مواضيع طبية MeSH: Fibrosis/*etiology , Fibrosis/*metabolism, Animals ; Biomarkers ; Bone Morphogenetic Proteins/metabolism ; Disease Susceptibility ; Extracellular Matrix/metabolism ; Fibrosis/diagnosis ; Fibrosis/therapy ; Humans ; Hypoxia/genetics ; Hypoxia/metabolism ; Molecular Targeted Therapy ; Myofibroblasts/drug effects ; Myofibroblasts/metabolism ; Myofibroblasts/pathology ; Oxidative Stress ; Research ; Signal Transduction/drug effects ; Transforming Growth Factor beta/metabolism

المؤلفون: Rosenbloom J; Jefferson Institute of Molecular Medicine, USA; Department of Dermatology and Cutaneous Biology, Thomas Jefferson University, USA. Electronic address: JoelRosenbloom@verizon.net., Mendoza FA, Jimenez SA

المصدر: Biochimica et biophysica acta [Biochim Biophys Acta] 2013 Jul; Vol. 1832 (7), pp. 1088-103. Date of Electronic Publication: 2012 Dec 21.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Elsevier Pub. Co Country of Publication: Netherlands NLM ID: 0217513 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0006-3002 (Print) Linking ISSN: 00063002 NLM ISO Abbreviation: Biochim Biophys Acta Subsets: MEDLINE

مواضيع طبية MeSH: Fibrosis* , Myofibroblasts*, Cytokines/metabolism ; Humans ; Intercellular Signaling Peptides and Proteins/metabolism ; Kidney Diseases/metabolism

المؤلفون: Busquets J; Jefferson Institute of Molecular Medicine, Thomas Jefferson University, 233 S. 10th Street, Philadelphia, PA 19107-5541, USA., Del Galdo F, Kissin EY, Jimenez SA

المصدر: Rheumatology (Oxford, England) [Rheumatology (Oxford)] 2010 Jun; Vol. 49 (6), pp. 1069-75. Date of Electronic Publication: 2010 Mar 04.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 100883501 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1462-0332 (Electronic) Linking ISSN: 14620324 NLM ISO Abbreviation: Rheumatology (Oxford) Subsets: MEDLINE

مواضيع طبية MeSH: Fibrosis/*pathology , Immunosuppressive Agents/*therapeutic use , Microscopy, Confocal/*methods , Mycophenolic Acid/*analogs & derivatives , Scleroderma, Systemic/*pathology, Adult ; Biopsy ; Case-Control Studies ; Clinical Trials as Topic ; Collagen/metabolism ; Female ; Fibrosis/drug therapy ; Humans ; Male ; Middle Aged ; Mycophenolic Acid/therapeutic use ; Scleroderma, Systemic/drug therapy ; Skin/anatomy & histology ; Skin/metabolism ; Statistics as Topic

المؤلفون: Rosenbloom J; Jefferson Institute of Molecular Medicine, Thomas Jefferson University, 233 South 10th Street, Room 509, Bluemle Life Science Building, Philadelphia, PA 19107-5541, USA., Castro SV, Jimenez SA

المصدر: Annals of internal medicine [Ann Intern Med] 2010 Feb 02; Vol. 152 (3), pp. 159-66.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: American College of Physicians--American Society of Internal Medicine Country of Publication: United States NLM ID: 0372351 Publication Model: Print Cited Medium: Internet ISSN: 1539-3704 (Electronic) Linking ISSN: 00034819 NLM ISO Abbreviation: Ann Intern Med Subsets: MEDLINE

مواضيع طبية MeSH: Fibrosis/*drug therapy , Fibrosis/*etiology, Fibrosis/pathology ; Humans ; Lymphotoxin-alpha/physiology

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المؤلفون: Jimenez, Sergio A, Piera-Velazquez, Sonsoles

المصدر: Rheumatology; Mar2023, Vol. 62 Issue 3, p999-1008, 10p

مصطلحات موضوعية: DISEASE progression, ENDOTHELIAL cells, EXOSOMES, FIBROSIS, SYSTEMIC scleroderma, GENE expression, PHENOTYPES