المؤلفون: László G. Puskás, Bence Szalai, Vigneshwari Subramanian, Róbert Alföldi, Julio Saez-Rodriguez, Christian H. Holland

المصدر: Nucleic Acids Research
Nucleic acids research 47(19), 10010-10026 (2019). doi:10.1093/nar/gkz805

مصطلحات موضوعية: Cell Survival, Cell, Computational biology, Biology, Transcriptome, 03 medical and health sciences, 0302 clinical medicine, Cell Line, Tumor, Drug Discovery, Genetics, medicine, Humans, Gene Regulatory Networks, Viability assay, Gene, Transcription factor, Cell Proliferation, 030304 developmental biology, 0303 health sciences, Cell Death, Drug discovery, Gene Expression Profiling, Computational Biology, Phenotype, medicine.anatomical_structure, 030220 oncology & carcinogenesis, ddc:540, Functional genomics, Software

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50dfac359b8be053376ebc200ff25bd0
https://doi.org/10.1093/nar/gkz805

المؤلفون: Steven J. Kunnen, Marije Niemeijer, Giulia Callegaro, Laura I. Furlong, Jeffrey J. Sutherland, Janet Piñero Gonzalez, Wouter den Hollander, Panuwat Trairatphisan, Bob van de Water, Yue Webster, Emre Guney, James L. Stevens, Julio Saez-Rodriguez, Jennifer Mollon, Solène Grosdidier

المساهمون: Medical Informatics

المصدر: Archives of Toxicology, 95(12), 3745-3775. Springer-Verlag
Archives of Toxicology
Archives of Toxicology, 95(12), 3745-3775

مصطلحات موضوعية: PHH, Health, Toxicology and Mutagenesis, Datasets as Topic, Computational biology, Biology, Toxicology, Risk Assessment, Toxicogenetics, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Species Specificity, medicine, Animals, Humans, Gene Regulatory Networks, Gene, Transcription factor, Acetaminophen, 030304 developmental biology, 0303 health sciences, WGCNA, Gene Expression Profiling, Tunicamycin, Endoplasmic reticulum, General Medicine, Mechanism-based risk assessment, Endoplasmic Reticulum Stress, Rats, Oxidative Stress, In Vitro Systems, medicine.anatomical_structure, chemistry, Hepatocyte, Cyclosporine, Hepatocytes, Unfolded protein response, Gene co-expression network, DILI, Chemical and Drug Induced Liver Injury, Toxicogenomics, ER stress, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cae839152101c7c0d415360667759ecf
https://pure.eur.nl/en/publications/b57c4814-0350-4abf-9941-fb822553e7c6

المؤلفون: Emre Guney, van de Water B, Julio Saez-Rodriguez, Laura I. Furlong, Steven J. Kunnen, Mollon J, den Hollander W, Giulia Callegaro, Janet Piñero Gonzalez, Yue Webster, Panuwat Trairatphisan, James L. Stevens, Solène Grosdidier, Jeffrey J. Sutherland, Marije Niemeijer

مصطلحات موضوعية: Transcriptome, Human hepatocyte, Microarray, Mechanism based, Computational biology, Biology, Toxicogenomics, Risk assessment, Gene, Transcription factor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c1eb37b5fdb99fe44d4150d637b7f307
https://doi.org/10.1101/2021.05.17.444463

المؤلفون: Julio Saez-Rodriguez, Graham R. Bignell, Euan A. Stronach, Beiyuan Fu, Angela Matchan, Fiona M. Behan, Emanuel Gonçalves, Ruby Banerjee, Elisabeth Chen, Ultan McDermott, Gabriele Picco, Fengtang Yang, Kosuke Yusa, Luz Garcia Alonso, Cyril H. Benes, David J. Dow, Adam Butler, Elizabeth Anderson, Francesco Iorio, Mathew J. Garnett

المصدر: Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, BRD4, CRISPR-Cas systems, Carcinogenesis, Science, General Physics and Astronomy, Datasets as Topic, Antineoplastic Agents, 02 engineering and technology, Computational biology, Biology, medicine.disease_cause, General Biochemistry, Genetics and Molecular Biology, Article, Fusion gene, 03 medical and health sciences, Targeted therapies, Cell Line, Tumor, Neoplasms, ROS1, medicine, Biomarkers, Tumor, Cancer genomics, CRISPR, Humans, lcsh:Science, Gene, Early Detection of Cancer, Regulation of gene expression, Multidisciplinary, Sequence Analysis, RNA, Gene Expression Profiling, Cancer, High-Throughput Nucleotide Sequencing, Functional genomics, General Chemistry, Genomics, 021001 nanoscience & nanotechnology, medicine.disease, Gene Expression Regulation, Neoplastic, 030104 developmental biology, Drug Resistance, Neoplasm, Cancer cell, lcsh:Q, Gene Fusion, 0210 nano-technology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e59227420fb1fc4592cbf1bb8cb97b3
https://doaj.org/article/faee146ac94c4c129948d57be9f339e0

المؤلفون: Patricio Godoy, Sebastian Mueller, Stefan Hoehme, Cristina Cadenas, Reham Hassan, Jörg Reinders, Steven Dooley, Maiju Myllys, Rosemarie Marchan, Julio Saez-Rodriguez, Ahmed Ghallab, Thomas Longerich, Ute Hofmann, Abdel-latif Seddek, Ricardo O. Ramirez Flores, Christian H. Holland, Jan G. Hengstler, Karolina Edlund, Brigitte Begher-Tibbe, Christian Rupp, Christian Trautwein, Verena Keitel

المصدر: Hepatology Communications
Hepatology communications 6(1), 161-177 (2021). doi:10.1002/hep4.1797
Hepatology communications, 6(1):161-177
Hepatology Communications, Vol 6, Iss 1, Pp 161-177 (2022)

مصطلحات موضوعية: Cell type, Period (gene), Down-Regulation, CCL4, RC799-869, Biology, Chronic liver disease, Transcriptome, 03 medical and health sciences, Mice, 0302 clinical medicine, Species Specificity, medicine, Animals, Humans, Gene, 030304 developmental biology, 0303 health sciences, Hepatology, Liver cell, Gene Expression Profiling, Liver Diseases, Original Articles, Diseases of the digestive system. Gastroenterology, medicine.disease, Molecular biology, Up-Regulation, Disease Models, Animal, Chronic Disease, 030211 gastroenterology & hepatology, Original Article, Immunostaining

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fade2e12d0d1d7dfaac19c7d9b240a2

المؤلفون: Jovan, Tanevski, Thin, Nguyen, Buu, Truong, Nikos, Karaiskos, Mehmet Eren Ahsen, Xinyu, Zhang, Chang, Shu, Ke, Xu, Xiaoyu, Liang, Ying, Hu, Hoang VV Pham, Xiaomei, Li, Thuc, D Le, Adi, L Tarca, Gaurav, Bhatti, Roberto, Romero, Nestoras, Karathanasis, Phillipe, Loher, Yang, Chen, Zhengqing, Ouyang, Disheng, Mao, Yuping, Zhang, Maryam, Zand, Jianhua, Ruan, Christoph, Hafemeister, Peng, Qiu, Duc, Tran, Tin, Nguyen, Attila, Gabor, Thomas, Yu, Justin, Guinney, Enrico, Glaab, Roland, Krause, Peter, Banda, DREAM SCTC Consortium, Baruzzo, Giacomo, Cappellato, Marco, Zorzan, Irene, DEL FAVERO, Simone, Schenato, Luca, Vandin, Fabio, DI CAMILLO, Barbara, Shruti, Gupta, Ajay Kumar Verma, Shandar, Ahmad, Ronesh, Sharma, Edwin, Vans, Alok, Sharma, Ashwini, Patil, Alejandra, Carrea, Alonso, Andres M., Luis, Diambra, Vijay, Narsapuram, Vinay, Kaikala, Chaitanyam, Potnuru, Sunil, Kumar, Jiajie, Peng, Xiaoyu, Wang, Xuequn, Shang, Dani, Livne, Tom, Snir, Hagit, Philip, Alona, Zilberberg, Sol, Efroni, Hamid Reza Hassanzadeh, Reihaneh, Hassanzadeh, Ghazal, Jahanshahi, M-Mahdi, Naddaf-Sh, Drayer, Phillip M., Sadra, Naddaf-Sh, Marouen Ben Guebila, Changlin, Wan, Yuchen, Cao, Saber, Meamardoost, Nan Papili Gao, Rudiyanto, Gunawan, Gustavo, Stolovitzky, Nikolaus, Rajewsky, Julio, Saez-Rodriguez, Pablo, Meyer

المساهمون: Tanevski, Jovan, Nguyen, Thin, Truong, Buu, Karaiskos, Nikos, Pham, Hoang Vv, Xiaomei, Li, Le, Thuc D, Meyer, Pablo, Dream SCTC consortuim

المصدر: Life Science Alliance

مصطلحات موضوعية: Health, Toxicology and Mutagenesis, Cell, Plant Science, In situ hybridization, Computational biology, Biology, Biochemistry, Genetics and Molecular Biology (miscellaneous), Transcriptome, 03 medical and health sciences, Spatial reconstruction, 0302 clinical medicine, mental disorders, Databases, Genetic, medicine, Animals, Gene Regulatory Networks, Gene, Spatial analysis, Spatial organization, Research Articles, Zebrafish, 030304 developmental biology, 0303 health sciences, Spatial Analysis, Ecology, Sequence Analysis, RNA, Gene Expression Profiling, RNA-seq technologies, Computational Biology, Gene Expression Regulation, Developmental, Gene selection, medicine.anatomical_structure, Cardiovascular and Metabolic Diseases, Single-cell RNA-sequencing (scRNAseq), Drosophila, Single-Cell Analysis, 030217 neurology & neurosurgery, psychological phenomena and processes, Algorithms, gene selection, Research Article, Forecasting

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24f19c28fbdbe4c77371a58fd92e3a3b
http://edoc.mdc-berlin.de/19409/1/19409oa.pdf

المؤلفون: Julio Saez-Rodriguez, Bence Szalai

مصطلحات موضوعية: Biophysics, Computational biology, Biology, Biochemistry, Regulon, 03 medical and health sciences, Classical complement pathway, Structural Biology, Transcription (biology), Neoplasms, Gene expression, Genetics, Humans, Gene Regulatory Networks, Molecular Biology, Gene, Transcription factor, 030304 developmental biology, 0303 health sciences, Information value, 030302 biochemistry & molecular biology, Gene sets, Cell Biology, Pathway analysis, Expression data, Cancer gene, Pathway activity, Signal Transduction, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69820880927ada3f78f5619d4b9ad3c3
https://doi.org/10.1101/2020.07.30.228296

المؤلفون: Patrick Most, Jobst-Hendrik Schultz, Ricardo O. Ramirez Flores, Rebecca T. Levinson, Julio Saez-Rodriguez, Jan D. Lanzer, Florian Leuschner, Christian H. Holland

مصطلحات موضوعية: Transcriptome, Proteome, Human heart, End stage heart failure, Disease, Computational biology, Biology, Reprogramming, Gene, Transcription factor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78214aa4e1d6c9a8b19e582dc8bbdf22
https://doi.org/10.1101/2020.05.23.20110858

المؤلفون: Xiaoyu Song, Michał Warchoł, Gustavo Stolovitzky, Samuel H. Payne, Piotr Stępniak, Mi Yang, Seohui Bae, Heewon Lee, Jaewoo Kang, Francesca Petralia, Boris Reva, Emily S. Boja, Sunkyu Kim, Thomas Yu, Weiping Ma, Yuanfang Guan, Julio Saez-Rodriguez, Henry Rodriguez, David Fenyö, Anna Calinawan, Zhi Li, Eunji Heo, Bora Lee, Jan Kaczmarczyk, Pei Wang, Paul C. Boutros, Hongyang Li, Han Yu

المصدر: SSRN Electronic Journal.

مصطلحات موضوعية: Transcriptome, Proteome, Phosphorylation, Genomics, Computational biology, Biology, Proteogenomics, Proteomics, Genome, Gene

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::41b8557bc2deee544d0501d98f21977f
https://doi.org/10.2139/ssrn.3554086

المؤلفون: Dénes Türei, Luz Garcia-Alonso, Mahmoud M. Ibrahim, Julio Saez-Rodriguez, Christian H. Holland

المصدر: Genome research 29(8), 1363-1375 (2019). doi:10.1101/gr.240663.118

مصطلحات موضوعية: Resource, 0303 health sciences, In silico, Gene regulatory network, Promoter, Computational biology, Biology, Chromatin, 03 medical and health sciences, 0302 clinical medicine, Regulon, ddc:540, Genetics, Gene, Chromatin immunoprecipitation, Transcription factor, 030217 neurology & neurosurgery, Genetics (clinical), 030304 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba31c6bb7fe994b009b346cba7685e17