المؤلفون: Pajic M; Division of Molecular Oncology, The Netherlands Cancer Institute, Amsterdam, the Netherlands.; The Kinghorn Cancer Centre, The Garvan Institute of Medical Research, Sydney, Australia.; St Vincent's Clinical School, Faculty of Medicine, University of New South Wales, New South Wales, Australia., Blatter S; Institute of Animal Pathology, Vetsuisse Faculty, University of Bern, Bern, Switzerland., Guyader C; Division of Molecular Oncology, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Gonggrijp M; Division of Molecular Oncology, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Kersbergen A; Division of Molecular Oncology, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Küçükosmanoğlu A; Division of Molecular Oncology, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Sol W; Division of Molecular Oncology, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Drost R; Division of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Jonkers J; Division of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Borst P; Division of Molecular Oncology, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Rottenberg S; Institute of Animal Pathology, Vetsuisse Faculty, University of Bern, Bern, Switzerland. sven.rottenberg@vetsuisse.unibe.ch.; Division of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam, the Netherlands.

المصدر: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2017 Nov 15; Vol. 23 (22), pp. 7020-7033. Date of Electronic Publication: 2017 Aug 18.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: The Association Country of Publication: United States NLM ID: 9502500 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Genes, BRCA1*, Antineoplastic Agents, Alkylating/*pharmacology , Breast Neoplasms/*genetics , Drug Resistance, Neoplasm/*genetics , Resting Phase, Cell Cycle/*drug effects , Resting Phase, Cell Cycle/*genetics, Animals ; Breast Neoplasms/drug therapy ; Breast Neoplasms/mortality ; Breast Neoplasms/pathology ; Cisplatin/pharmacology ; Disease Models, Animal ; Dose-Response Relationship, Drug ; Female ; Genes, p53 ; Humans ; Mice ; Mice, Knockout ; Nimustine/pharmacology

المؤلفون: Gong C; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital Campus, London, UK.; Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China., Fujino K; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital Campus, London, UK.; Department of Obstetrics & Gynecology, Faculty of Medicine, Juntendo University, Bunkyoku, Tokyo, Japan., Monteiro LJ; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital Campus, London, UK., Gomes AR; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital Campus, London, UK., Drost R; Division of Molecular Pathology and Cancer Genomics Centre Netherlands, The Netherlands Cancer Institute, Amsterdam, The Netherlands., Davidson-Smith H; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, UK., Takeda S; Department of Obstetrics & Gynecology, Faculty of Medicine, Juntendo University, Bunkyoku, Tokyo, Japan., Khoo US; Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China., Jonkers J; Division of Molecular Pathology and Cancer Genomics Centre Netherlands, The Netherlands Cancer Institute, Amsterdam, The Netherlands., Sproul D; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, UK., Lam EW; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital Campus, London, UK.

المصدر: Oncogene [Oncogene] 2015 Sep 24; Vol. 34 (39), pp. 5012-24. Date of Electronic Publication: 2014 Dec 22.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5594 (Electronic) Linking ISSN: 09509232 NLM ISO Abbreviation: Oncogene Subsets: MEDLINE

مواضيع طبية MeSH: DNA Methylation* , Gene Silencing* , Genes, BRCA1* , Promoter Regions, Genetic*, Breast Neoplasms/*genetics , Chromatin/*genetics , Hepatocyte Nuclear Factor 3-alpha/*genetics, Animals ; Breast Neoplasms/pathology ; Cell Line, Tumor ; DNA (Cytosine-5-)-Methyltransferases/metabolism ; Enhancer of Zeste Homolog 2 Protein ; Female ; Gene Knockdown Techniques ; Humans ; Mice ; Polycomb Repressive Complex 2/metabolism ; DNA Methyltransferase 3B

المؤلفون: Bouwman P; 1Division of Molecular Pathology and Cancer Genomics Centre and 2Department of Pathology, The Netherlands Cancer Institute Amsterdam, The Netherlands; and 3TaconicArtemis GmbH, Cologne, Germany., van der Gulden H, van der Heijden I, Drost R, Klijn CN, Prasetyanti P, Pieterse M, Wientjens E, Seibler J, Hogervorst FB, Jonkers J

المصدر: Cancer discovery [Cancer Discov] 2013 Oct; Vol. 3 (10), pp. 1142-55. Date of Electronic Publication: 2013 Jul 18.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101561693 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2159-8290 (Electronic) Linking ISSN: 21598274 NLM ISO Abbreviation: Cancer Discov Subsets: MEDLINE

مواضيع طبية MeSH: Genes, BRCA1* , Genetic Complementation Test* , Mutation, Missense*, BRCA1 Protein/*genetics , Breast Neoplasms/*genetics , High-Throughput Screening Assays/*methods , Ovarian Neoplasms/*genetics, Amino Acid Sequence ; Animals ; Antineoplastic Agents/pharmacology ; BRCA1 Protein/chemistry ; Cell Proliferation ; Cisplatin/pharmacology ; DNA Repair ; Drug Screening Assays, Antitumor ; Embryonic Stem Cells/physiology ; Female ; Genetic Variation ; Homologous Recombination ; Humans ; Mice ; Mice, Knockout ; Molecular Sequence Data ; Mutagenesis, Site-Directed ; Phthalazines/pharmacology ; Piperazines/pharmacology ; Poly(ADP-ribose) Polymerase Inhibitors ; RING Finger Domains

المؤلفون: Drost RM; Division of Molecular Biology, The Netherlands Cancer Institute, Plesmanlaan 121, Amsterdam 1066 CX, The Netherlands., Jonkers J

المصدر: British journal of cancer [Br J Cancer] 2009 Nov 17; Vol. 101 (10), pp. 1651-7. Date of Electronic Publication: 2009 Sep 29.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: Nature Publishing Group on behalf of Cancer Research UK Country of Publication: England NLM ID: 0370635 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-1827 (Electronic) Linking ISSN: 00070920 NLM ISO Abbreviation: Br J Cancer Subsets: MEDLINE

مواضيع طبية MeSH: Disease Models, Animal* , Genes, BRCA1*, Breast Neoplasms/*genetics , Mammary Neoplasms, Experimental/*genetics, Animals ; Female ; Humans ; Mice ; Mice, Knockout

المؤلفون: Puppe J; Molecular Genetics and Cancer Genomics Centre, Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands. Julianpuppe@gmx.de, Drost R, Liu X, Joosse SA, Evers B, Cornelissen-Steijger P, Nederlof P, Yu Q, Jonkers J, van Lohuizen M, Pietersen AM

المصدر: Breast cancer research : BCR [Breast Cancer Res] 2009; Vol. 11 (4), pp. R63. Date of Electronic Publication: 2009 Aug 26.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 100927353 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1465-542X (Electronic) Linking ISSN: 14655411 NLM ISO Abbreviation: Breast Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Genes, BRCA1*, Adenosine/*analogs & derivatives , BRCA1 Protein/*deficiency , Breast Neoplasms/*genetics , Histone-Lysine N-Methyltransferase/*physiology, Adenosine/pharmacology ; Animals ; BRCA1 Protein/genetics ; BRCA1 Protein/physiology ; Breast Neoplasms/pathology ; Cell Line, Tumor/drug effects ; Cell Line, Tumor/metabolism ; DNA Repair/genetics ; Drug Delivery Systems ; Enhancer of Zeste Homolog 2 Protein ; Female ; Gene Knockdown Techniques ; Histone-Lysine N-Methyltransferase/antagonists & inhibitors ; Histone-Lysine N-Methyltransferase/biosynthesis ; Histone-Lysine N-Methyltransferase/genetics ; Humans ; Mice ; Mutation ; Polycomb Repressive Complex 2 ; RNA, Messenger/biosynthesis ; RNA, Neoplasm/biosynthesis ; RNA, Small Interfering/pharmacology ; Recombinant Fusion Proteins/physiology