المؤلفون: Nielsen JB; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI 48109, USA; Department of Human Genetics, University of Michigan, Ann Arbor, MI 48109, USA., Fritsche LG; HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger 7600, Norway; Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health, Norwegian University of Science and Technology, Trondheim 7491, Norway., Zhou W; Department of Human Genetics, University of Michigan, Ann Arbor, MI 48109, USA; Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA., Teslovich TM; Regeneron Genetics Center, Tarrytown, NY 10591, USA., Holmen OL; HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger 7600, Norway; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health, Norwegian University of Science and Technology, Trondheim 7491, Norway; Department of Cardiology, St. Olav's University Hospital, Trondheim 7030, Norway., Gustafsson S; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala 75237, Sweden., Gabrielsen ME; HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger 7600, Norway; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health, Norwegian University of Science and Technology, Trondheim 7491, Norway., Schmidt EM; Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA., Beaumont R; Royal Devon & Exeter NHS Foundation Trust and University of Exeter Barrack Road Exeter, Exeter EX2 5WD, UK., Wolford BN; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI 48109, USA; Department of Human Genetics, University of Michigan, Ann Arbor, MI 48109, USA., Lin M; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI 48109, USA; Department of Human Genetics, University of Michigan, Ann Arbor, MI 48109, USA., Brummett CM; Department of Anesthesiology, University of Michigan, Ann Arbor, MI 48109, USA., Preuss MH; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Refsgaard L; Laboratory for Molecular Cardiology, Department of Cardiology, Rigshospitalet, University of Copenhagen, Copenhagen 2100, Denmark., Bottinger EP; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Mindich Child Health Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Graham SE; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI 48109, USA., Surakka I; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI 48109, USA., Chu Y; HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger 7600, Norway; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health, Norwegian University of Science and Technology, Trondheim 7491, Norway., Skogholt AH; HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger 7600, Norway; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health, Norwegian University of Science and Technology, Trondheim 7491, Norway., Dalen H; Department of Cardiology, St. Olav's University Hospital, Trondheim 7030, Norway; Department of Medicine, Levanger Hospital, Nord-Trøndelag Hospital Trust, Levanger 7600, Norway; Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim 7491, Norway., Boyle AP; Department of Human Genetics, University of Michigan, Ann Arbor, MI 48109, USA; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA., Oral H; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI 48109, USA., Herron TJ; Department of Internal Medicine, Center for Arrhythmia Research, University of Michigan, Ann Arbor, MI 48109, USA., Kitzman J; Department of Human Genetics, University of Michigan, Ann Arbor, MI 48109, USA., Jalife J; Department of Internal Medicine, Center for Arrhythmia Research, University of Michigan, Ann Arbor, MI 48109, USA; Fundacion Centro Nacional de Investigaciones Cardiovasculares, Madrid 28029, Spain., Svendsen JH; Laboratory for Molecular Cardiology, Department of Cardiology, Rigshospitalet, University of Copenhagen, Copenhagen 2100, Denmark; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen 2200, Denmark., Olesen MS; Laboratory for Molecular Cardiology, Department of Cardiology, Rigshospitalet, University of Copenhagen, Copenhagen 2100, Denmark; Department of Biomedicine, University of Copenhagen, Copenhagen 2200, Denmark., Njølstad I; Department of Community Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø 9019, Norway., Løchen ML; Department of Community Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø 9019, Norway., Baras A; Regeneron Genetics Center, Tarrytown, NY 10591, USA., Gottesman O; Regeneron Genetics Center, Tarrytown, NY 10591, USA., Marcketta A; Regeneron Genetics Center, Tarrytown, NY 10591, USA., O'Dushlaine C; Regeneron Genetics Center, Tarrytown, NY 10591, USA., Ritchie MD; Geisinger Health System, Danville, PA 17822, USA., Wilsgaard T; Department of Community Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø 9019, Norway., Loos RJF; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Frayling TM; Royal Devon & Exeter NHS Foundation Trust and University of Exeter Barrack Road Exeter, Exeter EX2 5WD, UK., Boehnke M; Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health, Norwegian University of Science and Technology, Trondheim 7491, Norway., Ingelsson E; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala 75237, Sweden; Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA., Carey DJ; Geisinger Health System, Danville, PA 17822, USA., Dewey FE; Regeneron Genetics Center, Tarrytown, NY 10591, USA., Kang HM; Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA., Abecasis GR; Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health, Norwegian University of Science and Technology, Trondheim 7491, Norway., Hveem K; HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger 7600, Norway; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health, Norwegian University of Science and Technology, Trondheim 7491, Norway; Department of Medicine, Levanger Hospital, Nord-Trøndelag Hospital Trust, Levanger 7600, Norway. Electronic address: kristian.hveem@ntnu.no., Willer CJ; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI 48109, USA; Department of Human Genetics, University of Michigan, Ann Arbor, MI 48109, USA; Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health, Norwegian University of Science and Technology, Trondheim 7491, Norway; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address: cristen@umich.edu.

المصدر: American journal of human genetics [Am J Hum Genet] 2018 Jan 04; Vol. 102 (1), pp. 103-115. Date of Electronic Publication: 2017 Dec 28.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 0370475 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1537-6605 (Electronic) Linking ISSN: 00029297 NLM ISO Abbreviation: Am J Hum Genet Subsets: MEDLINE

مواضيع طبية MeSH: Genetic Loci* , Genetic Predisposition to Disease* , Genome-Wide Association Study*, Atrial Fibrillation/*genetics , Heart/*embryology , Regulatory Sequences, Nucleic Acid/*genetics, Humans ; Inheritance Patterns/genetics ; Multifactorial Inheritance/genetics ; Organ Specificity/genetics ; Physical Chromosome Mapping ; Quantitative Trait Loci/genetics ; Reproducibility of Results ; Risk Factors

المؤلفون: Tsoi LC; Department of Dermatology, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA.; Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan 48109, USA.; Department of Computational Medicine &Bioinformatics, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA., Stuart PE; Department of Dermatology, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA., Tian C; 23andMe, Inc., Mountain View, California 94041, USA., Gudjonsson JE; Department of Dermatology, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA., Das S; Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan 48109, USA., Zawistowski M; Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan 48109, USA., Ellinghaus E; Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel 24105, Germany., Barker JN; St John's Institute of Dermatology, Division of Genetics and Molecular Medicine, Faculty of Life Sciences and Medicine, King's College London, London SE1 9RT, UK., Chandran V; Department of Medicine, Division of Rheumatology, University of Toronto, Toronto, Ontario, Canada M5S 1A8.; Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Research Institute, University of Toronto, Toronto, Ontario, Canada M5T 2S8., Dand N; St John's Institute of Dermatology, Division of Genetics and Molecular Medicine, Faculty of Life Sciences and Medicine, King's College London, London SE1 9RT, UK., Duffin KC; Department of Dermatology, University of Utah, Salt Lake City, Utah 84132, USA., Enerbäck C; Department of Dermatology, Linköping University, Linköping SE-581 83, Sweden., Esko T; Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA., Franke A; Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel 24105, Germany., Gladman DD; Department of Medicine, Division of Rheumatology, University of Toronto, Toronto, Ontario, Canada M5S 1A8.; Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Research Institute, University of Toronto, Toronto, Ontario, Canada M5T 2S8., Hoffmann P; Institute of Human Genetics, University of Bonn, Bonn 53127, Germany.; Division of Medical Genetics, Department of Biomedicine, University of Basel, Basel 4031, Switzerland., Kingo K; Dermatology Clinic, Tartu University Hospital, Department of Dermatology and Venereology, University of Tartu, Tartu 50417, Estonia., Kõks S; Department of Pathophysiology, Centre of Translational Medicine and Centre for Translational Genomics, University of Tartu, Tartu 50411, Estonia.; Department of Reproductive Biology, Estonian University of Life Sciences, Tartu 51006, Estonia., Krueger GG; Department of Dermatology, University of Utah, Salt Lake City, Utah 84132, USA., Lim HW; Department of Dermatology, Henry Ford Hospital, Detroit, Michigan 48202, USA., Metspalu A; Estonian Genome Center, University of Tartu, Tartu 51010, Estonia., Mrowietz U; Department of Dermatology, University Medical Center Schleswig-Holstein, Campus Kiel, Kiel 24105, Germany., Mucha S; Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel 24105, Germany., Rahman P; Memorial University, St. John's, Newfoundland, Newfoundland and Labrador, Canada A1B 3X9., Reis A; Institute of Human Genetics, FAU Erlangen-Nürnberg, Erlangen 91054, Germany., Tejasvi T; Department of Dermatology, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA.; Ann Arbor Veterans Affairs Hospital, Ann Arbor, Michigan 48105, USA., Trembath R; Department of Medical and Molecular Genetics, King's College London, London WC2R 2LS, UK., Voorhees JJ; Department of Dermatology, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA., Weidinger S; Department of Dermatology, University Medical Center Schleswig-Holstein, Campus Kiel, Kiel 24105, Germany., Weichenthal M; Department of Dermatology, University Medical Center Schleswig-Holstein, Campus Kiel, Kiel 24105, Germany., Wen X; Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan 48109, USA., Eriksson N; 23andMe, Inc., Mountain View, California 94041, USA., Kang HM; Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan 48109, USA., Hinds DA; 23andMe, Inc., Mountain View, California 94041, USA., Nair RP; Department of Dermatology, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA., Abecasis GR; Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan 48109, USA., Elder JT; Department of Dermatology, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA.; Ann Arbor Veterans Affairs Hospital, Ann Arbor, Michigan 48105, USA.

المصدر: Nature communications [Nat Commun] 2017 May 24; Vol. 8, pp. 15382. Date of Electronic Publication: 2017 May 24.

نوع المنشور: Journal Article; Meta-Analysis; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Genetic Predisposition to Disease* , Genome-Wide Association Study*, Genetic Loci/*genetics , Psoriasis/*genetics , White People/*genetics, Age of Onset ; Gene Regulatory Networks/genetics ; Gene Regulatory Networks/immunology ; Humans ; Interferons/immunology ; Interferons/metabolism ; NF-kappa B/immunology ; NF-kappa B/metabolism ; Polymorphism, Single Nucleotide ; Protein Interaction Maps/genetics ; Protein Interaction Maps/immunology ; Psoriasis/immunology ; Signal Transduction/genetics ; Signal Transduction/immunology ; T-Lymphocytes/immunology ; T-Lymphocytes/metabolism

المؤلفون: van der Harst P; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands; Durrer Center for Cardiovascular Research, Netherlands Heart Institute, Utrecht, the Netherlands. Electronic address: p.van.der.harst@umcg.nl., van Setten J; Department of Medical Genetics, University Medical Center Utrecht, Utrecht, the Netherlands; Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands., Verweij N; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Vogler G; Development, Aging and Regeneration, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California., Franke L; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Maurano MT; Department of Genome Sciences, University of Washington, Seattle, Washington; Department of Medicine, Division of Oncology, University of Washington, Seattle, Washington; Department of Pathology, New York University Langone Medical Center, New York, New York; Institute for Systems Genetics, New York University Langone Medical Center, New York, New York., Wang X; Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts., Mateo Leach I; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Eijgelsheim M; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, the Netherlands., Sotoodehnia N; Division of Cardiology, Cardiovascular Health Research Unit, University of Washington, Seattle, Washington., Hayward C; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland., Sorice R; Institute of Genetics and Biophysics A. Buzzati-Traverso, Naples, Italy., Meirelles O; Laboratory of Genetics, National Institute on Aging, Baltimore, Maryland., Lyytikäinen LP; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland; Department of Clinical Chemistry, University of Tampere School of Medicine, Tampere, Finland., Polašek O; Centre for Global Health Research, The Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland; Department of Public Health, Faculty of Medicine, University of Split, Split, Croatia., Tanaka T; Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland., Arking DE; Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland., Ulivi S; Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo,' Trieste, Italy., Trompet S; Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands; Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, the Netherlands., Müller-Nurasyid M; Department of Medicine I, University Hospital Munich, Campus Grosshadern, Ludwig-Maximilians-University, Munich, Germany; Institute of Medical Informatics, Biometry and Epidemiology, Genetic Epidemiology, Ludwig-Maximilians-Universität, Munich, Germany; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany., Smith AV; Icelandic Heart Association, Kópavogur, Iceland; University of Iceland, Reykjavik, Iceland., Dörr M; Department of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany; DZHK partner site, Greifswald, Germany., Kerr KF; Department of Biostatistics, University of Washington, Seattle, Washington., Magnani JW; Section of Cardiovascular Medicine, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts., Del Greco M F; Center for Biomedicine, European Academy of Bozen/Bolzano (EURAC), Bolzano, Italy (Affiliated Institute of the University of Lübeck, Lübeck, Germany)., Zhang W; Department of Epidemiology and Biostatistics, Imperial College London, London, United Kingdom; Ealing Hospital NHS Trust, Middlesex, United Kingdom., Nolte IM; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Silva CT; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands; Doctoral Program in Biomedical Sciences, Universidad del Rosario, Bogotá, Colombia; Department of Genetics (GENIUROS), Escuela de Medicina y Ciencias de la salud, Universidad del Rosario, Bogotá, Colombia., Padmanabhan S; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, United Kingdom., Tragante V; Department of Medical Genetics, University Medical Center Utrecht, Utrecht, the Netherlands; Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands., Esko T; Estonian Genome Center, University of Tartu, Tartu, Estonia; Division of Endocrinology and Center for Basic and Translational Obesity Research, Children's Hospital Boston, Boston, Massachusetts., Abecasis GR; Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan., Adriaens ME; Department of Experimental Cardiology, University of Amsterdam, Academic Medical Center, Amsterdam, the Netherlands; Maastricht Centre for Systems Biology, Maastricht University, Maastricht, the Netherlands., Andersen K; University of Iceland, Reykjavik, Iceland; Landspitali University Hospital, Reykjavik, Iceland., Barnett P; Department of Anatomy, Embryology and Physiology, University of Amsterdam, Academic Medical Center, Amsterdam, the Netherlands., Bis JC; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington., Bodmer R; Development, Aging and Regeneration, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California., Buckley BM; Department of Pharmacology and Therapeutics, University College Cork, Cork, Ireland., Campbell H; Centre for Global Health Research, The Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland., Cannon MV; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Chakravarti A; Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland., Chen LY; Department of Medicine, Cardiovascular Division, University of Minnesota, Minneapolis, Minnesota., Delitala A; Istituto di Ricerca Genetica e Biomedica, CNR, Monserrato, Cagliari, Italy., Devereux RB; Department of Medicine, Division of Cardiology, Weill Cornell Medicine, New York, New York., Doevendans PA; Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands., Dominiczak AF; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, United Kingdom., Ferrucci L; Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland., Ford I; Robertson Center for Biostatistics, University of Glasgow, Glasgow, United Kingdom., Gieger C; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Harris TB; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Bethesda, Maryland., Haugen E; Department of Genome Sciences, University of Washington, Seattle, Washington., Heinig M; Cardiovascular and Metabolic Diseases, Max-Delbrück-Center for Molecular Medicine (MDC), Berlin, Germany; Department of Computational Biology, Max Planck Institute for Molecular Genetics, Berlin, Germany; Institute of Computational Biology, Helmholtz Zentrum München, Neuherberg, Germany., Hernandez DG; Laboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland., Hillege HL; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Hirschhorn JN; Division of Endocrinology and Center for Basic and Translational Obesity Research, Children's Hospital Boston, Boston, Massachusetts; Medical and Population Genetics Program, Broad Institute, Cambridge, Massachusetts; Department of Genetics, Harvard Medical School, Boston, Massachusetts., Hofman A; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, the Netherlands., Hubner N; Cardiovascular and Metabolic Diseases, Max-Delbrück-Center for Molecular Medicine (MDC), Berlin, Germany; DZHK partner site, Berlin, Germany., Hwang SJ; Population Sciences Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland., Iorio A; Cardiovascular Department and Postgraduate School of Cardiovascular Disease, University of Trieste, Trieste, Italy., Kähönen M; Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland; Department of Clinical Physiology, University of Tampere School of Medicine, Tampere, Finland., Kellis M; Computer Science and Artificial Intelligence Lab, Massachusetts Institute of Technology, Cambridge, Massachusetts; Broad Institute, Cambridge, Massachusetts., Kolcic I; Department of Public Health, Faculty of Medicine, University of Split, Split, Croatia., Kooner IK; Ealing Hospital NHS Trust, Middlesex, United Kingdom., Kooner JS; Ealing Hospital NHS Trust, Middlesex, United Kingdom; National Heart and Lung Institute, Imperial College London, London, United Kingdom., Kors JA; Department of Medical Informatics, Erasmus Medical Center, Rotterdam, the Netherlands., Lakatta EG; Laboratory of Cardiovascular Science, National Institute on Aging, Baltimore, Maryland., Lage K; Broad Institute, Cambridge, Massachusetts; Department of Surgery, Massachusetts General Hospital, Boston, Massachusetts; Harvard Medical School, Harvard University, Boston, Massachusetts., Launer LJ; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Bethesda, Maryland., Levy D; Center for Population Studies, National Heart, Lung, and Blood Institute, National Institute of Health, Bethesda, Maryland., Lundby A; Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Macfarlane PW; Electrocardiology Section, Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, United Kingdom., May D; Department of Family Medicine, Clalit Health Services, and The Hebrew University-Hadassah Medical School, Jerusalem, Israel., Meitinger T; DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany; Institute of Human Genetics, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; Institute of Human Genetics, Technische Universität München, Munich, Germany., Metspalu A; Estonian Genome Center, University of Tartu, Tartu, Estonia., Nappo S; Institute of Genetics and Biophysics A. Buzzati-Traverso, Naples, Italy., Naitza S; Istituto di Ricerca Genetica e Biomedica, CNR, Monserrato, Cagliari, Italy., Neph S; Department of Genome Sciences, University of Washington, Seattle, Washington., Nord AS; Genomics Division, Lawrence Berkeley National Laboratory, Berkeley, California; Center for Neuroscience, Departments of Neurobiology, Physiology, and Behavior and Psychiatry and Behavioral Sciences, University of California, Davis, California., Nutile T; Institute of Genetics and Biophysics A. Buzzati-Traverso, Naples, Italy., Okin PM; Department of Medicine, Division of Cardiology, Weill Cornell Medicine, New York, New York., Olsen JV; Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Oostra BA; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands., Penninger JM; Institute of Molecular Biotechnology of the Austrian Academy of Sciences, Vienna, Austria., Pennacchio LA; Genomics Division, Lawrence Berkeley National Laboratory, Berkeley, California; DOE Joint Genome Institute, Walnut Creek, California., Pers TH; Division of Endocrinology and Center for Basic and Translational Obesity Research, Children's Hospital Boston, Boston, Massachusetts; Medical and Population Genetics Program, Broad Institute, Cambridge, Massachusetts; Novo Nordisk Foundation Centre for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark., Perz S; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; Institute for Biological and Medical Imaging, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Peters A; DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Pinto YM; Department of Experimental Cardiology, University of Amsterdam, Academic Medical Center, Amsterdam, the Netherlands., Pfeufer A; Center for Biomedicine, European Academy of Bozen/Bolzano (EURAC), Bolzano, Italy (Affiliated Institute of the University of Lübeck, Lübeck, Germany); Department of Bioinformatics and Systems Biology IBIS, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Pilia MG; Istituto di Ricerca Genetica e Biomedica, CNR, Monserrato, Cagliari, Italy., Pramstaller PP; Center for Biomedicine, European Academy of Bozen/Bolzano (EURAC), Bolzano, Italy (Affiliated Institute of the University of Lübeck, Lübeck, Germany); Department of Neurology, General Central Hospital, Bolzano, Italy; Department of Neurology, University of Lübeck, Lübeck, Germany., Prins BP; Cardiogenetics Lab, Human Genetics Research Centre, St. George's University of London, London, United Kingdom., Raitakari OT; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland., Raychaudhuri S; Division of Genetics, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts., Rice KM; Department of Biostatistics, University of Washington, Seattle, Washington., Rossin EJ; Harvard Medical School, Harvard University, Boston, Massachusetts; Analytical and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts., Rotter JI; Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute and Department of Pediatrics and Medicine, Harbor-UCLA Medical Center, Torrance, California., Schafer S; Cardiovascular and Metabolic Diseases, Max-Delbrück-Center for Molecular Medicine (MDC), Berlin, Germany; DZHK partner site, Berlin, Germany; National Heart Research Institute Singapore, National Heart Centre Singapore, Singapore., Schlessinger D; Laboratory of Genetics, National Institute on Aging, Baltimore, Maryland., Schmidt CO; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany., Sehmi J; Ealing Hospital NHS Trust, Middlesex, United Kingdom; National Heart and Lung Institute, Imperial College London, London, United Kingdom., Silljé HHW; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Sinagra G; Cardiovascular Department and Postgraduate School of Cardiovascular Disease, University of Trieste, Trieste, Italy., Sinner MF; Department of Medicine I, University Hospital Munich, Campus Grosshadern, Ludwig-Maximilians-University, Munich, Germany., Slowikowski K; Bioinformatics and Integrative Genomics, Harvard University, Cambridge, Massachusetts., Soliman EZ; Epidemiological Cardiology Research Center, Wake Forest School of Medicine, Winston Salem, North Carolina., Spector TD; Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom., Spiering W; Department of Vascular Medicine, University Medical Center Utrecht, Utrecht, the Netherlands., Stamatoyannopoulos JA; Department of Genome Sciences, University of Washington, Seattle, Washington., Stolk RP; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Strauch K; Institute of Medical Informatics, Biometry and Epidemiology, Genetic Epidemiology, Ludwig-Maximilians-Universität, Munich, Germany; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Tan ST; Ealing Hospital NHS Trust, Middlesex, United Kingdom; National Heart and Lung Institute, Imperial College London, London, United Kingdom., Tarasov KV; Laboratory of Cardiovascular Science, National Institute on Aging, Baltimore, Maryland., Trinh B; Development, Aging and Regeneration, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California., Uitterlinden AG; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, the Netherlands., van den Boogaard M; Department of Anatomy, Embryology and Physiology, University of Amsterdam, Academic Medical Center, Amsterdam, the Netherlands., van Duijn CM; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands., van Gilst WH; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Viikari JS; Division of Medicine, Turku University Hospital, Turku, Finland; Department of Medicine, University of Turku, Turku, Finland., Visscher PM; Queensland Brain Institute, University of Queensland, St. Lucia, Australia; University of Queensland Diamantina Institute, Translational Research Institute, Woolloongabba, Australia., Vitart V; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland., Völker U; DZHK partner site, Greifswald, Germany; Department of Functional Genomics, Interfaculty Institute of Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany., Waldenberger M; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Weichenberger CX; Center for Biomedicine, European Academy of Bozen/Bolzano (EURAC), Bolzano, Italy (Affiliated Institute of the University of Lübeck, Lübeck, Germany)., Westra HJ; Medical and Population Genetics Program, Broad Institute, Cambridge, Massachusetts; Divisions of Genetics and Rheumatology, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts; Partners Center for Personalized Genetic Medicine, Boston, Massachusetts., Wijmenga C; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Wolffenbuttel BH; Department of Endocrinology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Yang J; Queensland Brain Institute, University of Queensland, St. Lucia, Australia., Bezzina CR; Department of Experimental Cardiology, University of Amsterdam, Academic Medical Center, Amsterdam, the Netherlands., Munroe PB; Clinical Pharmacology and Barts and The London Genome Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom; National Institute for Health Research Biomedical Research Unit, Barts and the London School of Medicine, Queen Mary University of London, London, United Kingdom., Snieder H; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Wright AF; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland., Rudan I; Centre for Global Health Research, The Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland., Boyer LA; Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts., Asselbergs FW; Durrer Center for Cardiovascular Research, Netherlands Heart Institute, Utrecht, the Netherlands; Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands; Institute of Cardiovascular Science, Faculty of Population Health Sciences, University College London, London, United Kingdom., van Veldhuisen DJ; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Stricker BH; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, the Netherlands., Psaty BM; Departments of Medicine, Epidemiology, and Health Services, Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; Group Health Research Institute, Group Health Cooperative, Seattle, Washington., Ciullo M; Institute of Genetics and Biophysics A. Buzzati-Traverso, Naples, Italy; IRCCS Neuromed, Isernia, Italy., Sanna S; Istituto di Ricerca Genetica e Biomedica, CNR, Monserrato, Cagliari, Italy., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland; Department of Clinical Chemistry, University of Tampere School of Medicine, Tampere, Finland., Wilson JF; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland; Centre for Global Health Research, The Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland., Bandinelli S; Geriatric Unit, Azienda Sanitaria Firenze, Florence, Italy., Alonso A; Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia., Gasparini P; Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo,' Trieste, Italy; University of Trieste, Trieste, Italy; Sidra Medical and Research Center, Doha, Qatar., Jukema JW; Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands; Netherlands Heart Institute, Utrecht, the Netherlands., Kääb S; Department of Medicine I, University Hospital Munich, Campus Grosshadern, Ludwig-Maximilians-University, Munich, Germany; DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany., Gudnason V; Icelandic Heart Association, Kópavogur, Iceland; University of Iceland, Reykjavik, Iceland., Felix SB; Department of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany; DZHK partner site, Greifswald, Germany., Heckbert SR; Group Health Research Institute, Group Health Cooperative, Seattle, Washington; Department of Epidemiology, University of Washington, Seattle, Washington., de Boer RA; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Newton-Cheh C; Medical and Population Genetics Program, Broad Institute, Cambridge, Massachusetts; Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts; Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts., Hicks AA; Center for Biomedicine, European Academy of Bozen/Bolzano (EURAC), Bolzano, Italy (Affiliated Institute of the University of Lübeck, Lübeck, Germany)., Chambers JC; Department of Epidemiology and Biostatistics, Imperial College London, London, United Kingdom; Ealing Hospital NHS Trust, Middlesex, United Kingdom., Jamshidi Y; Cardiogenetics Lab, Human Genetics Research Centre, St. George's University of London, London, United Kingdom., Visel A; Genomics Division, Lawrence Berkeley National Laboratory, Berkeley, California; DOE Joint Genome Institute, Walnut Creek, California; School of Natural Sciences, University of California, Merced, California., Christoffels VM; Department of Anatomy, Embryology and Physiology, University of Amsterdam, Academic Medical Center, Amsterdam, the Netherlands., Isaacs A; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands; CARIM School for Cardiovascular Diseases, Maastricht Centre for Systems Biology, Department of Biochemistry, Maastricht University, Maastricht, the Netherlands., Samani NJ; Department of Cardiovascular Sciences, University of Leicester, BHF Cardiovascular Research Centre, Glenfield Hospital, Leicester, United Kingdom; National Institute for Health Research, Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester, United Kingdom., de Bakker PIW; Department of Medical Genetics, University Medical Center Utrecht, Utrecht, the Netherlands; Department of Epidemiology, University Medical Center Utrecht, Utrecht, the Netherlands.

المصدر: Journal of the American College of Cardiology [J Am Coll Cardiol] 2016 Sep 27; Vol. 68 (13), pp. 1435-1448.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Biomedical Country of Publication: United States NLM ID: 8301365 Publication Model: Print Cited Medium: Internet ISSN: 1558-3597 (Electronic) Linking ISSN: 07351097 NLM ISO Abbreviation: J Am Coll Cardiol Subsets: MEDLINE

مواضيع طبية MeSH: Genetic Loci* , Genome-Wide Association Study*, Cardiomegaly/*genetics, Animals ; Humans

المؤلفون: Stuart PE; Department of Dermatology, University of Michigan Medical School, Ann Arbor, MI 48109, USA., Nair RP; Department of Dermatology, University of Michigan Medical School, Ann Arbor, MI 48109, USA., Tsoi LC; Department of Dermatology, University of Michigan Medical School, Ann Arbor, MI 48109, USA; Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA., Tejasvi T; Department of Dermatology, University of Michigan Medical School, Ann Arbor, MI 48109, USA; Ann Arbor Veterans Affairs Hospital, Ann Arbor, MI 48105, USA., Das S; Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA., Kang HM; Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA., Ellinghaus E; Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, 24105 Kiel, Germany., Chandran V; Department of Medicine, Division of Rheumatology, University of Toronto, Toronto, ON M5T 2S8, Canada; Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Research Institute, University of Toronto, Toronto, ON M5T 2S8, Canada., Callis-Duffin K; Department of Dermatology, University of Utah, Salt Lake City, UT 84132, USA., Ike R; Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI 48109, USA., Li Y; Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA., Wen X; Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA., Enerbäck C; Department of Clinical and Experimental Medicine, Division of Cell Biology and Dermatology, Linköping University, 581 83 Linköping, Sweden., Gudjonsson JE; Department of Dermatology, University of Michigan Medical School, Ann Arbor, MI 48109, USA., Kõks S; Department of Pathophysiology, Centre of Translational Medicine and Centre for Translational Genomics, University of Tartu, 50411 Tartu, Estonia; Department of Reproductive Biology, Estonian University of Life Sciences, 51014 Tartu, Estonia., Kingo K; Dermatology Clinic, Tartu University Hospital, Department of Dermatology and Venereology, University of Tartu, 50417 Tartu, Estonia., Esko T; Estonian Genome Center, University of Tartu, 51010 Tartu, Estonia., Mrowietz U; Department of Dermatology, University Medical Center Schleswig-Holstein, Campus Kiel, 24105 Kiel, Germany., Reis A; Institute of Human Genetics, University of Erlangen-Nuremberg, 91054 Erlangen, Germany., Wichmann HE; Institute of Epidemiology I, Helmholtz Zentrum Munich, German Research Center for Environmental Health, 85764 Neuherberg, Germany; Institute of Medical Informatics, Biometry and Epidemiology, Ludwig-Maximilians-University, 81377 Munich, Germany; Institute of Medical Statistics and Epidemiology, Technical University Munich, 80333 Munich, Germany., Gieger C; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, 85764 Neuherberg, Germany; Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, 85764 Neuherberg, Germany., Hoffmann P; Institute of Human Genetics, University of Bonn, 53127 Bonn, Germany; Department of Genomics, Life & Brain Center, University of Bonn, 53127 Bonn, Germany., Nöthen MM; Institute of Human Genetics, University of Bonn, 53127 Bonn, Germany; Department of Genomics, Life & Brain Center, University of Bonn, 53127 Bonn, Germany., Winkelmann J; Neurologische Klinik and Poliklinik, Klinikum rechts der Isar, Technische Universität München, 80333 Munich, Germany; Institute of Neurogenomics, Helmholtz Zentrum Munchen, German Research Center for Environmental Health, 85764 Neuherberg, Germany., Kunz M; Department of Dermatology, Venereology and Allergology, University of Leipzig, 04103 Leipzig, Germany., Moreta EG; Saint Paul Rheumatology, Eagan, MN 55121, USA., Mease PJ; Seattle Rheumatology Associates, 601 Broadway, Suite 600, Seattle, WA 98122, USA., Ritchlin CT; Allergy, Immunology, and Rheumatology Division, University of Rochester Medical Center, Rochester, NY 14623, USA., Bowcock AM; National Heart and Lung Institute, Imperial College, London SW7 2AZ, UK., Krueger GG; Department of Dermatology, University of Utah, Salt Lake City, UT 84132, USA., Lim HW; Department of Dermatology, Henry Ford Hospital, Detroit, MI 48202, USA., Weidinger S; Department of Dermatology, University Medical Center Schleswig-Holstein, Campus Kiel, 24105 Kiel, Germany., Weichenthal M; Department of Dermatology, University Medical Center Schleswig-Holstein, Campus Kiel, 24105 Kiel, Germany., Voorhees JJ; Department of Dermatology, University of Michigan Medical School, Ann Arbor, MI 48109, USA., Rahman P; Memorial University, St. John's, NL A1C 5B8, Canada., Gregersen PK; The Feinstein Institute for Medical Research, North Shore-Long Island Jewish Health System, Manhasset, NY 11030, USA., Franke A; Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, 24105 Kiel, Germany., Gladman DD; Department of Medicine, Division of Rheumatology, University of Toronto, Toronto, ON M5T 2S8, Canada; Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Research Institute, University of Toronto, Toronto, ON M5T 2S8, Canada., Abecasis GR; Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA., Elder JT; Department of Dermatology, University of Michigan Medical School, Ann Arbor, MI 48109, USA; Ann Arbor Veterans Affairs Hospital, Ann Arbor, MI 48105, USA. Electronic address: jelder@umich.edu.

المصدر: American journal of human genetics [Am J Hum Genet] 2015 Dec 03; Vol. 97 (6), pp. 816-36. Date of Electronic Publication: 2015 Nov 28.

نوع المنشور: Journal Article; Meta-Analysis; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 0370475 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1537-6605 (Electronic) Linking ISSN: 00029297 NLM ISO Abbreviation: Am J Hum Genet Subsets: MEDLINE

مواضيع طبية MeSH: Genetic Loci* , Genetic Predisposition to Disease* , Polymorphism, Single Nucleotide*, Arthritis, Psoriatic/*genetics , Psoriasis/*genetics, Adolescent ; Adult ; Arthritis, Psoriatic/pathology ; Bayes Theorem ; Case-Control Studies ; Cornified Envelope Proline-Rich Proteins/genetics ; DNA-Binding Proteins/genetics ; Female ; Genome-Wide Association Study ; HLA-C Antigens/genetics ; Humans ; Intracellular Signaling Peptides and Proteins/genetics ; Linkage Disequilibrium ; Male ; Nuclear Proteins/genetics ; Psoriasis/pathology ; Receptors, Interleukin/genetics ; Tumor Necrosis Factor Receptor Superfamily, Member 9/genetics ; Tumor Necrosis Factor alpha-Induced Protein 3

المؤلفون: Gaulton KJ; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Department of Genetics, Stanford University, Stanford, California, USA., Ferreira T; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Lee Y; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA., Raimondo A; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK., Mägi R; Estonian Genome Center, University of Tartu, Tartu, Estonia., Reschen ME; Centre for Cellular and Molecular Physiology, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Mahajan A; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Locke A; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA., Rayner NW; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK.; Wellcome Trust Sanger Institute, Hinxton, UK., Robertson N; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK., Scott RA; Medical Research Council (MRC) Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, UK., Prokopenko I; Genomics of Common Disease, Imperial College London, London, UK., Scott LJ; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA., Green T; Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA., Sparso T; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Thuillier D; Lille Institute of Biology, European Genomics Institute of Diabetes, Lille, France., Yengo L; Lille Institute of Biology, European Genomics Institute of Diabetes, Lille, France., Grallert H; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research, Neuherberg, Germany., Wahl S; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research, Neuherberg, Germany., Frånberg M; Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.; Science for Life Laboratory, Stockholm, Sweden.; Department for Numerical Analysis and Computer Science, Stockholm University, Stockholm, Sweden., Strawbridge RJ; Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden., Kestler H; Leibniz Institute for Age Research, Fritz Lipmann Institute, Jena, Germany.; Medical Systems Biology, Ulm University, Ulm, Germany., Chheda H; Finnish Institute for Molecular Medicine (FIMM), Helsinki, Finland., Eisele L; Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, Essen, Germany., Gustafsson S; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Steinthorsdottir V; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland., Thorleifsson G; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland., Qi L; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA.; Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA.; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.; Department of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, New Orleans, Louisiana, USA., Karssen LC; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands., van Leeuwen EM; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands., Willems SM; Medical Research Council (MRC) Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, UK.; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands., Li M; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA., Chen H; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA.; Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts, USA., Fuchsberger C; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA., Kwan P; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA., Ma C; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA., Linderman M; Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Lu Y; Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Thomsen SK; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK., Rundle JK; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK., Beer NL; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK., van de Bunt M; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK., Chalisey A; Centre for Cellular and Molecular Physiology, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Kang HM; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA., Voight BF; Department of Pharmacology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Abecasis GR; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA., Almgren P; Lund University Diabetes Centre, Department of Clinical Science Malmo, Scania University Hospital, Lund University, Malmo, Sweden., Baldassarre D; Centro Cardiologico Monzino, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Milan, Italy.; Dipartimento di Scienze Farmacologiche e Biomolecolari, Università di Milano, Milan, Italy., Balkau B; INSERM Centre de Recherche Epidémiologie et Santé des Populations (CESP) U1018, Villejuif, France.; University Paris Sud 11, UMRS 1018, Villejuif, France., Benediktsson R; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.; Landspitali University Hospital, Reykjavik, Iceland., Blüher M; Integrated Treatment and Research (IFB) Center for Adiposity Diseases, University of Leipzig, Leipzig, Germany.; Department of Medicine, University of Leipzig, Leipzig, Germany., Boeing H; German Institute of Human Nutrition, Potsdam-Rehbruecke, Germany., Bonnycastle LL; National Human Genome Research Institute, US National Institutes of Health, Bethesda, Maryland, USA., Bottinger EP; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Burtt NP; Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA., Carey J; Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA., Charpentier G; Endocrinology-Diabetology Unit, Corbeil-Essonnes Hospital, Corbeil-Essonnes, France., Chines PS; National Human Genome Research Institute, US National Institutes of Health, Bethesda, Maryland, USA., Cornelis MC; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA., Couper DJ; Collaborative Studies Coordinating Center, Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Crenshaw AT; Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA., van Dam RM; Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA.; Saw Swee Hock School of Public Health, National University of Singapore, Singapore., Doney AS; Diabetes Research Centre, Biomedical Research Institute, University of Dundee, Ninewells Hospital, Dundee, UK.; Pharmacogenomics Centre, Biomedical Research Institute, University of Dundee, Ninewells Hospital, Dundee, UK., Dorkhan M; Lund University Diabetes Centre, Department of Clinical Science Malmo, Novo Nordisk Scandinavia, Malmo, Sweden., Edkins S; Wellcome Trust Sanger Institute, Hinxton, UK., Eriksson JG; Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland.; Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland.; Unit of General Practice, Helsinki University General Hospital, Helsinki, Finland.; Folkhalsan Research Center, Helsinki, Finland., Esko T; Estonian Genome Center, University of Tartu, Tartu, Estonia.; Division of Endocrinology, Children's Hospital, Boston, Massachusetts, USA.; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA., Eury E; CNRS UMR 8199, Institute of Biology and Lille 2 University, Pasteur Institute, Lille, France., Fadista J; Lund University Diabetes Centre, Department of Clinical Science Malmo, Scania University Hospital, Lund University, Malmo, Sweden., Flannick J; Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA., Fontanillas P; Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA., Fox C; National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, Massachusetts, USA.; Division of Endocrinology and Metabolism, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA., Franks PW; Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA.; Lund University Diabetes Centre, Department of Clinical Science Malmo, Scania University Hospital, Lund University, Malmo, Sweden.; Department of Clinical Sciences, Lund University, Malmo, Sweden.; Department of Public Health and Clinical Medicine, Umea University, Umea, Sweden., Gertow K; Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden., Gieger C; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Gigante B; Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Gottesman O; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Grant GB; Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA., Grarup N; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Groves CJ; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK., Hassinen M; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland., Have CT; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Herder C; Institute for Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich Heine University Dusseldorf, Dusseldorf, Germany.; German Center for Diabetes Research, partner site Dusseldorf, Dusseldorf, Germany., Holmen OL; Nord-Trøndelag Health Study (HUNT) Research Center, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger, Norway., Hreidarsson AB; Landspitali University Hospital, Reykjavik, Iceland., Humphries SE; Cardiovascular Genetics, British Heart Foundation (BHF) Laboratories, Institute of Cardiovascular Sciences, University College London, London, UK., Hunter DJ; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA.; Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA.; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.; Program in Genetic Epidemiology and Statistical Genetics, Harvard School of Public Health, Boston, Massachusetts, USA., Jackson AU; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA., Jonsson A; Lund University Diabetes Centre, Department of Clinical Science Malmo, Scania University Hospital, Lund University, Malmo, Sweden., Jørgensen ME; Steno Diabetes Center, Gentofte, Denmark., Jørgensen T; Research Centre for Prevention and Health, Capital Region of Denmark, Copenhagen, Denmark.; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Faculty of Medicine, University of Aalborg, Aalborg, Denmark., Kao WH; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA., Kerrison ND; Medical Research Council (MRC) Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, UK., Kinnunen L; Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland., Klopp N; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Hannover Unified Biobank, Hannover Medical School, Hannover, Germany., Kong A; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland., Kovacs P; Integrated Treatment and Research (IFB) Center for Adiposity Diseases, University of Leipzig, Leipzig, Germany.; Department of Medicine, University of Leipzig, Leipzig, Germany., Kraft P; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA.; Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts, USA.; Program in Genetic Epidemiology and Statistical Genetics, Harvard School of Public Health, Boston, Massachusetts, USA., Kravic J; Lund University Diabetes Centre, Department of Clinical Science Malmo, Scania University Hospital, Lund University, Malmo, Sweden., Langford C; Wellcome Trust Sanger Institute, Hinxton, UK., Leander K; Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Liang L; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA.; Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts, USA., Lichtner P; Institute of Human Genetics, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Lindgren CM; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA., Lindholm E; Lund University Diabetes Centre, Department of Clinical Science Malmo, Scania University Hospital, Lund University, Malmo, Sweden., Linneberg A; Research Centre for Prevention and Health, Capital Region of Denmark, Copenhagen, Denmark.; Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Liu CT; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA., Lobbens S; CNRS UMR 8199, Institute of Biology and Lille 2 University, Pasteur Institute, Lille, France., Luan J; Medical Research Council (MRC) Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, UK., Lyssenko V; Lund University Diabetes Centre, Department of Clinical Science Malmo, Scania University Hospital, Lund University, Malmo, Sweden.; Steno Diabetes Center, Gentofte, Denmark., Männistö S; Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland., McLeod O; Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden., Meyer J; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Mihailov E; Estonian Genome Center, University of Tartu, Tartu, Estonia., Mirza G; Biomedical Research Centre Genomics Core Facility, Guy's and St Thomas' National Health Service (NHS) Foundation Trust, Guy's &St Thomas' Hospital, London, UK., Mühleisen TW; Institute of Human Genetics, University of Bonn, Bonn, Germany.; Department of Genomics, Life and Brain Center, University of Bonn, Bonn, Germany.; Institute of Neuroscience and Medicine (INM-1), Research Centre Jülich, Jülich, Germany., Müller-Nurasyid M; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Department of Medicine I, University Hospital Grosshadern, Ludwig Maximilians Universität, Munich, Germany.; Institute of Medical Informatics, Biometry and Epidemiology, Chair of Genetic Epidemiology, Ludwig Maximilians Universität, Neuherberg, Germany.; DZHK (German Center for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany., Navarro C; Department of Epidemiology, Murcia Regional Health Council, Instituto Murciano de Investigación Biosanitaria Virgen de la Arrixaca (IMIB-Arrixaca), Murcia, Spain.; Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.; Department of Health and Social Sciences, Universidad de Murcia, Murcia, Spain., Nöthen MM; Institute of Human Genetics, University of Bonn, Bonn, Germany.; Department of Genomics, Life and Brain Center, University of Bonn, Bonn, Germany., Oskolkov NN; Lund University Diabetes Centre, Department of Clinical Science Malmo, Scania University Hospital, Lund University, Malmo, Sweden., Owen KR; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK.; Oxford National Institute for Health Research Biomedical Research Centre, Churchill Hospital, Oxford, UK., Palli D; Cancer Research and Prevention Institute (ISPO), Florence, Italy., Pechlivanis S; Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, Essen, Germany., Peltonen L; Wellcome Trust Sanger Institute, Hinxton, UK.; Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA.; Finnish Institute for Molecular Medicine (FIMM), Helsinki, Finland.; Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland., Perry JR; Medical Research Council (MRC) Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, UK., Platou CG; Nord-Trøndelag Health Study (HUNT) Research Center, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger, Norway.; Department of Internal Medicine, Levanger Hospital, Nord-Trondelag Health Trust, Levanger, Norway., Roden M; Institute for Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich Heine University Dusseldorf, Dusseldorf, Germany.; German Center for Diabetes Research, partner site Dusseldorf, Dusseldorf, Germany.; Department of Endocrinology and Diabetology, University Hospital Dusseldorf, Dusseldorf, Germany., Ruderfer D; Division of Psychiatric Genomics, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Rybin D; Boston University Data Coordinating Center, Boston, Massachusetts, USA., van der Schouw YT; University Medical Center Utrecht, Utrecht, the Netherlands., Sennblad B; Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.; Science for Life Laboratory, Stockholm, Sweden., Sigurðsson G; Landspitali University Hospital, Reykjavik, Iceland.; Icelandic Heart Association, Kopavogur, Iceland., Stančáková A; Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Steinbach G; Department of Clinical Chemistry and Central Laboratory, University of Ulm, Ulm, Germany., Storm P; Lund University Diabetes Centre, Department of Clinical Science Malmo, Scania University Hospital, Lund University, Malmo, Sweden., Strauch K; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Medical Informatics, Biometry and Epidemiology, Chair of Genetic Epidemiology, Ludwig Maximilians Universität, Neuherberg, Germany., Stringham HM; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA., Sun Q; Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA.; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA., Thorand B; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research, Neuherberg, Germany., Tikkanen E; Finnish Institute for Molecular Medicine (FIMM), Helsinki, Finland.; Department of Public Health, Hjelt Institute, University of Helsinki, Helsinki, Finland., Tonjes A; Integrated Treatment and Research (IFB) Center for Adiposity Diseases, University of Leipzig, Leipzig, Germany.; Department of Medicine, University of Leipzig, Leipzig, Germany., Trakalo J; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Tremoli E; Centro Cardiologico Monzino, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Milan, Italy.; Dipartimento di Scienze Farmacologiche e Biomolecolari, Università di Milano, Milan, Italy., Tuomi T; Finnish Institute for Molecular Medicine (FIMM), Helsinki, Finland.; Folkhalsan Research Center, Helsinki, Finland.; Department of Endocrinology, Abdominal Center, Helsinki University Hospital, Helsinki, Finland.; Research Program for Diabetes and Obesity, University of Helsinki, Helsinki, Finland., Wennauer R; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands., Wiltshire S; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Wood AR; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, UK., Zeggini E; Wellcome Trust Sanger Institute, Hinxton, UK., Dunham I; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Hinxton, UK., Birney E; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Hinxton, UK., Pasquali L; Division of Endocrinology, Germans Trias i Pujol University Hospital and Research Institute, Badalona, Spain.; Josep Carreras Leukaemia Research Institute, Badalona, Spain.; CIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Barcelona, Spain., Ferrer J; Department of Medicine, Imperial College London, London, UK.; Institut d'Investigacions Biomèdiques August Pi i Sunyer, Centre Esther Koplowitz, Barcelona, Spain., Loos RJ; Medical Research Council (MRC) Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, UK.; Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Dupuis J; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA.; National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, Massachusetts, USA., Florez JC; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA.; Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA.; Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA.; Diabetes Research Center, Diabetes Unit, Massachusetts General Hospital, Boston, Massachusetts, USA., Boerwinkle E; Human Genetics Center, University of Texas Health Science Center at Houston, Houston, Texas, USA.; Human Genome Sequencing Center at Baylor College of Medicine, Houston, Texas, USA., Pankow JS; Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, Minnesota, USA., van Duijn C; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands.; Netherlands Genomics Initiative, Netherlands Consortium for Healthy Ageing and Center for Medical Systems Biology, Rotterdam, the Netherlands., Sijbrands E; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands., Meigs JB; Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA.; General Medicine Division, Massachusetts General Hospital, Boston, Massachusetts, USA., Hu FB; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA.; Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA.; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA., Thorsteinsdottir U; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Stefansson K; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Lakka TA; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.; Institute of Biomedicine/Physiology, University of Eastern Finland, Kuopio, Finland.; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland., Rauramaa R; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland., Stumvoll M; Integrated Treatment and Research (IFB) Center for Adiposity Diseases, University of Leipzig, Leipzig, Germany.; Department of Medicine, University of Leipzig, Leipzig, Germany., Pedersen NL; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Lind L; Department of Medical Sciences, Uppsala University Hospital, Uppsala, Sweden., Keinanen-Kiukaanniemi SM; Faculty of Medicine, Institute of Health Sciences, University of Oulu, Oulu, Finland.; Unit of General Practice, Oulu University Hospital, Oulu, Finland., Korpi-Hyövälti E; South Ostrobothnia Central Hospital, Seinajoki, Finland., Saaristo TE; Finnish Diabetes Association, Tampere, Finland.; Pirkanmaa District Hospital, Tampere, Finland., Saltevo J; Department of Medicine, Central Finland Central Hospital, Jyvasklya, Finland., Kuusisto J; Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Laakso M; Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Metspalu A; Estonian Genome Center, University of Tartu, Tartu, Estonia.; Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia., Erbel R; Clinic of Cardiology, West German Heart Centre, University Hospital of Essen, University Duisdurg-Essen, Essen, Germany., Jöcke KH; Institute of Biomedicine/Physiology, University of Eastern Finland, Kuopio, Finland., Moebus S; Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, Essen, Germany., Ripatti S; Wellcome Trust Sanger Institute, Hinxton, UK.; Finnish Institute for Molecular Medicine (FIMM), Helsinki, Finland.; Department of Public Health, Hjelt Institute, University of Helsinki, Helsinki, Finland.; Public Health Genomics Unit, National Institute for Health and Welfare, Helsinki, Finland., Salomaa V; Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland., Ingelsson E; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Boehm BO; Division of Endocrinology and Diabetes, Department of Internal Medicine, University Medical Centre Ulm, Ulm, Germany.; Lee Kong Chian School of Medicine, Imperial College London and Nanyang Technological University, Singapore., Bergman RN; Diabetes and Obesity Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA., Collins FS; National Human Genome Research Institute, US National Institutes of Health, Bethesda, Maryland, USA., Mohlke KL; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Koistinen H; Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland.; Division of Endocrinology, Department of Medicine, Helsinki University Central Hospital, Helsinki, Finland.; Minerva Foundation Institute for Medical Research, Helsinki, Finland., Tuomilehto J; Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland.; Instituto de Investigación Sanitaria del Hospital Universitario La Paz, Madrid, Spain.; Centre for Vascular Prevention, Danube University Krems, Krems, Austria.; Diabetes Research Group, King Abdulaziz University, Jeddah, Saudi Arabia., Hveem K; Nord-Trøndelag Health Study (HUNT) Research Center, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger, Norway., Njølstad I; Department of Community Medicine, Faculty of Health Sciences, University of Tromso, Tromso, Norway., Deloukas P; Wellcome Trust Sanger Institute, Hinxton, UK.; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Donnelly PJ; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Department of Statistics, University of Oxford, Oxford, UK., Frayling TM; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, UK., Hattersley AT; Institute of Biomedical and Clinical Science, University of Exeter Medical School, Exeter, UK., de Faire U; Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Hamsten A; Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden., Illig T; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Hannover Unified Biobank, Hannover Medical School, Hannover, Germany., Peters A; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research, Neuherberg, Germany.; DZHK (German Center for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany., Cauchi S; Lille Institute of Biology, European Genomics Institute of Diabetes, Lille, France., Sladek R; Montreal Diabetes Research Center, Centre de Recherche du Centre Hospitalier de l'Université de Montréal, Montreal, Quebec, Canada.; McGill University and Génome Québec Innovation Centre, Montreal, Quebec, Canada., Froguel P; Genomics of Common Disease, Imperial College London, London, UK.; Lille Institute of Biology, European Genomics Institute of Diabetes, Lille, France.; CNRS UMR 8199, Institute of Biology and Lille 2 University, Pasteur Institute, Lille, France., Hansen T; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark., Pedersen O; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Morris AD; Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Palmer CN; Diabetes Research Centre, Biomedical Research Institute, University of Dundee, Ninewells Hospital, Dundee, UK.; Pharmacogenomics Centre, Biomedical Research Institute, University of Dundee, Ninewells Hospital, Dundee, UK., Kathiresan S; Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA.; Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA.; Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA., Melander O; Lund University Diabetes Centre, Department of Clinical Science Malmo, Scania University Hospital, Lund University, Malmo, Sweden., Nilsson PM; Lund University Diabetes Centre, Department of Clinical Science Malmo, Scania University Hospital, Lund University, Malmo, Sweden., Groop LC; Finnish Institute for Molecular Medicine (FIMM), Helsinki, Finland.; Lund University Diabetes Centre, Department of Clinical Science Malmo, Scania University Hospital, Lund University, Malmo, Sweden., Barroso I; Wellcome Trust Sanger Institute, Hinxton, UK.; University of Cambridge Metabolic Research Laboratories, Wellcome Trust-MRC Institute of Metabolic Science, Cambridge, UK.; National Institute for Health Research Cambridge Biomedical Research Centre, Cambridge, UK., Langenberg C; Medical Research Council (MRC) Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, UK., Wareham NJ; Medical Research Council (MRC) Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, UK., O'Callaghan CA; Centre for Cellular and Molecular Physiology, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Gloyn AL; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK.; Oxford National Institute for Health Research Biomedical Research Centre, Churchill Hospital, Oxford, UK., Altshuler D; Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA.; Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA.; Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA.; Diabetes Research Center, Diabetes Unit, Massachusetts General Hospital, Boston, Massachusetts, USA.; Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA.; Department of Molecular Biology, Harvard Medical School, Boston, Massachusetts, USA., Boehnke M; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA., Teslovich TM; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA., McCarthy MI; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK.; Oxford National Institute for Health Research Biomedical Research Centre, Churchill Hospital, Oxford, UK., Morris AP; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Estonian Genome Center, University of Tartu, Tartu, Estonia.; Department of Biostatistics, University of Liverpool, Liverpool, UK.; Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, UK.

مؤلفون مشاركون: DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium

المصدر: Nature genetics [Nat Genet] 2015 Dec; Vol. 47 (12), pp. 1415-25. Date of Electronic Publication: 2015 Nov 09.

نوع المنشور: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE

مواضيع طبية MeSH: Chromosome Mapping* , Genetic Loci* , Genetic Predisposition to Disease*, Diabetes Mellitus, Type 2/*genetics , Hepatocyte Nuclear Factor 3-beta/*genetics , Polymorphism, Single Nucleotide/*genetics , Receptor, Melatonin, MT2/*genetics, Binding Sites ; Case-Control Studies ; Chromatin Immunoprecipitation ; Gene Expression Regulation ; Genome-Wide Association Study ; Genomics ; Hepatocyte Nuclear Factor 3-beta/metabolism ; Humans ; Islets of Langerhans/metabolism ; Islets of Langerhans/pathology ; Liver/metabolism ; Liver/pathology ; Molecular Sequence Annotation ; Receptor, Melatonin, MT2/metabolism

المؤلفون: Fritsche LG; Institute of Human Genetics, University of Regensburg, Regensburg, Germany., Chen W, Schu M, Yaspan BL, Yu Y, Thorleifsson G, Zack DJ, Arakawa S, Cipriani V, Ripke S, Igo RP Jr, Buitendijk GH, Sim X, Weeks DE, Guymer RH, Merriam JE, Francis PJ, Hannum G, Agarwal A, Armbrecht AM, Audo I, Aung T, Barile GR, Benchaboune M, Bird AC, Bishop PN, Branham KE, Brooks M, Brucker AJ, Cade WH, Cain MS, Campochiaro PA, Chan CC, Cheng CY, Chew EY, Chin KA, Chowers I, Clayton DG, Cojocaru R, Conley YP, Cornes BK, Daly MJ, Dhillon B, Edwards AO, Evangelou E, Fagerness J, Ferreyra HA, Friedman JS, Geirsdottir A, George RJ, Gieger C, Gupta N, Hagstrom SA, Harding SP, Haritoglou C, Heckenlively JR, Holz FG, Hughes G, Ioannidis JP, Ishibashi T, Joseph P, Jun G, Kamatani Y, Katsanis N, N Keilhauer C, Khan JC, Kim IK, Kiyohara Y, Klein BE, Klein R, Kovach JL, Kozak I, Lee CJ, Lee KE, Lichtner P, Lotery AJ, Meitinger T, Mitchell P, Mohand-Saïd S, Moore AT, Morgan DJ, Morrison MA, Myers CE, Naj AC, Nakamura Y, Okada Y, Orlin A, Ortube MC, Othman MI, Pappas C, Park KH, Pauer GJ, Peachey NS, Poch O, Priya RR, Reynolds R, Richardson AJ, Ripp R, Rudolph G, Ryu E, Sahel JA, Schaumberg DA, Scholl HP, Schwartz SG, Scott WK, Shahid H, Sigurdsson H, Silvestri G, Sivakumaran TA, Smith RT, Sobrin L, Souied EH, Stambolian DE, Stefansson H, Sturgill-Short GM, Takahashi A, Tosakulwong N, Truitt BJ, Tsironi EE, Uitterlinden AG, van Duijn CM, Vijaya L, Vingerling JR, Vithana EN, Webster AR, Wichmann HE, Winkler TW, Wong TY, Wright AF, Zelenika D, Zhang M, Zhao L, Zhang K, Klein ML, Hageman GS, Lathrop GM, Stefansson K, Allikmets R, Baird PN, Gorin MB, Wang JJ, Klaver CC, Seddon JM, Pericak-Vance MA, Iyengar SK, Yates JR, Swaroop A, Weber BH, Kubo M, Deangelis MM, Léveillard T, Thorsteinsdottir U, Haines JL, Farrer LA, Heid IM, Abecasis GR

مؤلفون مشاركون: AMD Gene Consortium

المصدر: Nature genetics [Nat Genet] 2013 Apr; Vol. 45 (4), pp. 433-9, 439e1-2. Date of Electronic Publication: 2013 Mar 03.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE

مواضيع طبية MeSH: Biomarkers/*metabolism , Genetic Loci/*genetics , Macular Degeneration/*genetics , Polymorphism, Single Nucleotide/*genetics, Case-Control Studies ; Female ; Genetic Predisposition to Disease ; Genome-Wide Association Study ; Humans ; Male ; Meta-Analysis as Topic ; Risk Factors

المؤلفون: Ellinghaus D; Institute of Clinical Molecular Biology, Christian-Albrechts-University, 24105 Kiel, Germany., Ellinghaus E, Nair RP, Stuart PE, Esko T, Metspalu A, Debrus S, Raelson JV, Tejasvi T, Belouchi M, West SL, Barker JN, Kõks S, Kingo K, Balschun T, Palmieri O, Annese V, Gieger C, Wichmann HE, Kabesch M, Trembath RC, Mathew CG, Abecasis GR, Weidinger S, Nikolaus S, Schreiber S, Elder JT, Weichenthal M, Nothnagel M, Franke A

المصدر: American journal of human genetics [Am J Hum Genet] 2012 Apr 06; Vol. 90 (4), pp. 636-47.

نوع المنشور: Journal Article; Meta-Analysis

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 0370475 Publication Model: Print Cited Medium: Internet ISSN: 1537-6605 (Electronic) Linking ISSN: 00029297 NLM ISO Abbreviation: Am J Hum Genet Subsets: MEDLINE

مواضيع طبية MeSH: Genetic Loci*, Crohn Disease/*genetics , Genetic Predisposition to Disease/*genetics , Psoriasis/*genetics, Exons/genetics ; Female ; Gene Expression/genetics ; Genome-Wide Association Study ; Humans ; Male ; Polymorphism, Single Nucleotide/genetics ; Quantitative Trait Loci/genetics

المؤلفون: Johnson T; Clinical Pharmacology and Barts and The London Genome Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London, UK. t.johnson@qmul.ac.uk, Gaunt TR, Newhouse SJ, Padmanabhan S, Tomaszewski M, Kumari M, Morris RW, Tzoulaki I, O'Brien ET, Poulter NR, Sever P, Shields DC, Thom S, Wannamethee SG, Whincup PH, Brown MJ, Connell JM, Dobson RJ, Howard PJ, Mein CA, Onipinla A, Shaw-Hawkins S, Zhang Y, Davey Smith G, Day IN, Lawlor DA, Goodall AH, Fowkes FG, Abecasis GR, Elliott P, Gateva V, Braund PS, Burton PR, Nelson CP, Tobin MD, van der Harst P, Glorioso N, Neuvrith H, Salvi E, Staessen JA, Stucchi A, Devos N, Jeunemaitre X, Plouin PF, Tichet J, Juhanson P, Org E, Putku M, Sõber S, Veldre G, Viigimaa M, Levinsson A, Rosengren A, Thelle DS, Hastie CE, Hedner T, Lee WK, Melander O, Wahlstrand B, Hardy R, Wong A, Cooper JA, Palmen J, Chen L, Stewart AF, Wells GA, Westra HJ, Wolfs MG, Clarke R, Franzosi MG, Goel A, Hamsten A, Lathrop M, Peden JF, Seedorf U, Watkins H, Ouwehand WH, Sambrook J, Stephens J, Casas JP, Drenos F, Holmes MV, Kivimaki M, Shah S, Shah T, Talmud PJ, Whittaker J, Wallace C, Delles C, Laan M, Kuh D, Humphries SE, Nyberg F, Cusi D, Roberts R, Newton-Cheh C, Franke L, Stanton AV, Dominiczak AF, Farrall M, Hingorani AD, Samani NJ, Caulfield MJ, Munroe PB

مؤلفون مشاركون: Cardiogenics Consortium, Global BPgen Consortium

المصدر: American journal of human genetics [Am J Hum Genet] 2011 Dec 09; Vol. 89 (6), pp. 688-700. Date of Electronic Publication: 2011 Nov 17.

نوع المنشور: Journal Article; Meta-Analysis; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 0370475 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1537-6605 (Electronic) Linking ISSN: 00029297 NLM ISO Abbreviation: Am J Hum Genet Subsets: MEDLINE

مواضيع طبية MeSH: Genetic Loci* , Oligonucleotide Array Sequence Analysis*, Hypertension/*genetics, Adult ; Aged ; Blood Pressure/genetics ; Case-Control Studies ; Female ; Gene Expression Profiling ; Gene Frequency ; Genome-Wide Association Study ; Haplotypes ; Humans ; Linkage Disequilibrium ; Male ; Methylenetetrahydrofolate Reductase (NADPH2)/genetics ; Middle Aged ; Plasma Membrane Calcium-Transporting ATPases/genetics ; Polymorphism, Single Nucleotide ; Receptors, Atrial Natriuretic Factor/genetics ; Sequence Analysis, DNA

المؤلفون: Sanna S; Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche (CNR), Monserrato, Italy. serena.sanna@inn.cnr.it, Li B, Mulas A, Sidore C, Kang HM, Jackson AU, Piras MG, Usala G, Maninchedda G, Sassu A, Serra F, Palmas MA, Wood WH 3rd, Njølstad I, Laakso M, Hveem K, Tuomilehto J, Lakka TA, Rauramaa R, Boehnke M, Cucca F, Uda M, Schlessinger D, Nagaraja R, Abecasis GR

المصدر: PLoS genetics [PLoS Genet] 2011 Jul; Vol. 7 (7), pp. e1002198. Date of Electronic Publication: 2011 Jul 28.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1553-7404 (Electronic) Linking ISSN: 15537390 NLM ISO Abbreviation: PLoS Genet Subsets: MEDLINE

مواضيع طبية MeSH: Chromosome Mapping* , Genetic Variation*, Cholesterol, LDL/*genetics , Genetic Loci/*genetics, Genetic Predisposition to Disease ; Genome-Wide Association Study ; Humans ; Italy ; Polymorphism, Single Nucleotide/genetics ; White People/genetics

المؤلفون: Lango Allen H; Genetics of Complex Traits, Peninsula College of Medicine and Dentistry, University of Exeter, Exeter EX1 2LU, UK., Estrada K, Lettre G, Berndt SI, Weedon MN, Rivadeneira F, Willer CJ, Jackson AU, Vedantam S, Raychaudhuri S, Ferreira T, Wood AR, Weyant RJ, Segrè AV, Speliotes EK, Wheeler E, Soranzo N, Park JH, Yang J, Gudbjartsson D, Heard-Costa NL, Randall JC, Qi L, Vernon Smith A, Mägi R, Pastinen T, Liang L, Heid IM, Luan J, Thorleifsson G, Winkler TW, Goddard ME, Sin Lo K, Palmer C, Workalemahu T, Aulchenko YS, Johansson A, Zillikens MC, Feitosa MF, Esko T, Johnson T, Ketkar S, Kraft P, Mangino M, Prokopenko I, Absher D, Albrecht E, Ernst F, Glazer NL, Hayward C, Hottenga JJ, Jacobs KB, Knowles JW, Kutalik Z, Monda KL, Polasek O, Preuss M, Rayner NW, Robertson NR, Steinthorsdottir V, Tyrer JP, Voight BF, Wiklund F, Xu J, Zhao JH, Nyholt DR, Pellikka N, Perola M, Perry JR, Surakka I, Tammesoo ML, Altmaier EL, Amin N, Aspelund T, Bhangale T, Boucher G, Chasman DI, Chen C, Coin L, Cooper MN, Dixon AL, Gibson Q, Grundberg E, Hao K, Juhani Junttila M, Kaplan LM, Kettunen J, König IR, Kwan T, Lawrence RW, Levinson DF, Lorentzon M, McKnight B, Morris AP, Müller M, Suh Ngwa J, Purcell S, Rafelt S, Salem RM, Salvi E, Sanna S, Shi J, Sovio U, Thompson JR, Turchin MC, Vandenput L, Verlaan DJ, Vitart V, White CC, Ziegler A, Almgren P, Balmforth AJ, Campbell H, Citterio L, De Grandi A, Dominiczak A, Duan J, Elliott P, Elosua R, Eriksson JG, Freimer NB, Geus EJ, Glorioso N, Haiqing S, Hartikainen AL, Havulinna AS, Hicks AA, Hui J, Igl W, Illig T, Jula A, Kajantie E, Kilpeläinen TO, Koiranen M, Kolcic I, Koskinen S, Kovacs P, Laitinen J, Liu J, Lokki ML, Marusic A, Maschio A, Meitinger T, Mulas A, Paré G, Parker AN, Peden JF, Petersmann A, Pichler I, Pietiläinen KH, Pouta A, Ridderstråle M, Rotter JI, Sambrook JG, Sanders AR, Schmidt CO, Sinisalo J, Smit JH, Stringham HM, Bragi Walters G, Widen E, Wild SH, Willemsen G, Zagato L, Zgaga L, Zitting P, Alavere H, Farrall M, McArdle WL, Nelis M, Peters MJ, Ripatti S, van Meurs JB, Aben KK, Ardlie KG, Beckmann JS, Beilby JP, Bergman RN, Bergmann S, Collins FS, Cusi D, den Heijer M, Eiriksdottir G, Gejman PV, Hall AS, Hamsten A, Huikuri HV, Iribarren C, Kähönen M, Kaprio J, Kathiresan S, Kiemeney L, Kocher T, Launer LJ, Lehtimäki T, Melander O, Mosley TH Jr, Musk AW, Nieminen MS, O'Donnell CJ, Ohlsson C, Oostra B, Palmer LJ, Raitakari O, Ridker PM, Rioux JD, Rissanen A, Rivolta C, Schunkert H, Shuldiner AR, Siscovick DS, Stumvoll M, Tönjes A, Tuomilehto J, van Ommen GJ, Viikari J, Heath AC, Martin NG, Montgomery GW, Province MA, Kayser M, Arnold AM, Atwood LD, Boerwinkle E, Chanock SJ, Deloukas P, Gieger C, Grönberg H, Hall P, Hattersley AT, Hengstenberg C, Hoffman W, Lathrop GM, Salomaa V, Schreiber S, Uda M, Waterworth D, Wright AF, Assimes TL, Barroso I, Hofman A, Mohlke KL, Boomsma DI, Caulfield MJ, Cupples LA, Erdmann J, Fox CS, Gudnason V, Gyllensten U, Harris TB, Hayes RB, Jarvelin MR, Mooser V, Munroe PB, Ouwehand WH, Penninx BW, Pramstaller PP, Quertermous T, Rudan I, Samani NJ, Spector TD, Völzke H, Watkins H, Wilson JF, Groop LC, Haritunians T, Hu FB, Kaplan RC, Metspalu A, North KE, Schlessinger D, Wareham NJ, Hunter DJ, O'Connell JR, Strachan DP, Wichmann HE, Borecki IB, van Duijn CM, Schadt EE, Thorsteinsdottir U, Peltonen L, Uitterlinden AG, Visscher PM, Chatterjee N, Loos RJ, Boehnke M, McCarthy MI, Ingelsson E, Lindgren CM, Abecasis GR, Stefansson K, Frayling TM, Hirschhorn JN

المصدر: Nature [Nature] 2010 Oct 14; Vol. 467 (7317), pp. 832-8. Date of Electronic Publication: 2010 Sep 29.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: Body Height/*genetics , Genetic Loci/*genetics , Genome, Human/*genetics , Metabolic Networks and Pathways/*genetics , Polymorphism, Single Nucleotide/*genetics, Chromosomes, Human, Pair 3/genetics ; Genetic Predisposition to Disease/genetics ; Genome-Wide Association Study ; Humans ; Multifactorial Inheritance/genetics ; Phenotype