المؤلفون: Saunders GRB; Department of Psychology, University of Minnesota, Minneapolis, MN, USA., Wang X; Department of Public Health Sciences, Penn State College of Medicine, Hershey, PA, USA., Chen F; Department of Public Health Sciences, Penn State College of Medicine, Hershey, PA, USA., Jang SK; Department of Psychology, University of Minnesota, Minneapolis, MN, USA., Liu M; Department of Psychology, University of Minnesota, Minneapolis, MN, USA., Wang C; Department of Public Health Sciences, Penn State College of Medicine, Hershey, PA, USA., Gao S; Department of Public Health Sciences, Penn State College of Medicine, Hershey, PA, USA., Jiang Y; Department of Epidemiology & Population Health at Stanford University, Stanford, CA, USA., Khunsriraksakul C; Department of Public Health Sciences, Penn State College of Medicine, Hershey, PA, USA., Otto JM; Department of Psychology, University of Minnesota, Minneapolis, MN, USA., Addison C; Jackson Heart Study (JHS) Graduate Training and Education Center (GTEC), Department of Epidemiology and Biostatistics, School of Public Health, Jackson State University, Jackson, MS, USA., Akiyama M; Laboratory for Statistical and Translational Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.; Department of Ocular Pathology and Imaging Science, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan., Albert CM; Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.; Division of Preventive Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Aliev F; Department of Psychiatry, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, USA., Alonso A; Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA., Arnett DK; Dean's Office and Department of Epidemiology, College of Public Health, University of Kentucky, Lexington, KY, USA., Ashley-Koch AE; Department of Medicine and Duke Comprehensive Sickle Cell Center, Duke University School of Medicine, Durham, NC, USA.; Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, USA., Ashrani AA; 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deCODE Genetics/Amgen, Inc., Reykjavik, Iceland., Blangero J; Department of Human Genetics and South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX, USA., Bleecker ER; Department of Medicine, University of Arizona, Tucson, AZ, USA., Boardman JD; Institute of Behavioral Science, University of Colorado Boulder, Boulder, CO, USA., Boerwinkle E; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA., Boomsma DI; Netherlands Twin Register, Dept Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands., Boorgula MP; Division of Biomedical Informatics & Personalized Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Bowden DW; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, USA., Brody JA; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA., Cade BE; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA, USA.; Division of Sleep Medicine, Harvard Medical School, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA., Chasman DI; Division of Preventive Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Chavan S; Division of Biomedical Informatics & Personalized Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Chen YI; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Chen Z; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.; MRC Population Health Research Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK., Cheng I; Department of Epidemiology & Biostatistics, University of California, San Francisco, CA, USA.; UCSF Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA, USA., Cho MH; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Choquet H; Kaiser Permanente Northern California (KPNC), Division of Research, Oakland, CA, USA., Cole JW; Department of Neurology, Baltimore Veterans Affairs Medical Center, Baltimore, MD, USA.; Division of Vascular Neurology, Department of Neurology, University of Maryland School of Medicine, Baltimore, MD, USA., Cornelis MC; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Cucca F; University of Sassari, Sassari SS, Italy., Curran JE; Department of Human Genetics and South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX, USA., de Andrade M; Division of Clinical Trials and Biostatistics, Department of Quantitative Health Sciences, Mayo Clinic College of Medicine and Science, Rochester, MN, USA., Dick DM; Department of Psychiatry, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, USA., Docherty AR; Department of Psychiatry, University of Utah School of Medicine, Salt Lake City, UT, USA.; Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Virginia, USA.; Huntsman Mental Health Institute, Salt Lake City, UT, USA., Duggirala R; Department of Human Genetics and South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX, USA., Eaton CB; Department of Family Medicine, Brown University, Providence, RI, USA., Ehringer MA; Institute for Behavioral Genetics, University of Colorado Boulder, Boulder, CO, USA.; Department of Integrative Physiology, University of Colorado Boulder, Boulder, CO, USA., Esko T; Institute of Genomics, University of Tartu, Tartu, Estonia., Faul JD; 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Chan School of Public Health, Boston, MA, USA., Ma J; Population Sciences Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.; Division of Nutrition Epidemiology and Data Science, Friedman School of Nutrition Science and Policy, Tufts University, Boston, MA, USA., Mägi R; Department of Integrative Physiology, University of Colorado Boulder, Boulder, CO, USA., Manichaikul A; Center for Public Health Genomics, Department of Public Health Sciences, University of Virginia School of Medicine, Charlottesville, VA, USA., Martin NG; Genetic Epidemiology, QIMR Berghofer Medical Research Institute, Brisbane, Australia., Mathur R; GenOmics, Bioinformatics, and Translational Research Center, RTI International, Research Triangle Park, NC, USA., Matoba N; Laboratory for Statistical and Translational Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.; Department of Genetics, UNC Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., McArdle PF; Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA., McGue M; Department of Psychology, University of Minnesota, Minneapolis, MN, USA., McQueen MB; Department of Integrative Physiology, University of Colorado, Boulder, CO, USA., Medland SE; Psychiatric Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Australia., Metspalu A; Institute of Genomics, University of Tartu, Tartu, Estonia., Meyers DA; Department of Medicine, University of Arizona, Tucson, AZ, USA., Millwood IY; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.; MRC Population Health Research Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK., Mitchell BD; Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.; Geriatrics Research and Education Clinical Center, Baltimore Veterans Administration Medical Center, Baltimore, MD, USA., Mohlke KL; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Moll M; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Montasser ME; Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA., Morrison AC; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA., Mulas A; Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche (CNR), Monserrato, Italy., Nielsen JB; K.G. 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مؤلفون مشاركون: 23andMe Research Team, Biobank Japan Project

المصدر: Nature [Nature] 2022 Dec; Vol. 612 (7941), pp. 720-724. Date of Electronic Publication: 2022 Dec 07.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: Genetic Predisposition to Disease*/genetics , Genetic Variation*/genetics , Multifactorial Inheritance*/genetics , Tobacco Use*/genetics , Alcohol Drinking*/genetics , Internationality*, Humans ; Genome-Wide Association Study/methods ; Risk Factors ; Transcriptome ; Sample Size ; Genetic Loci/genetics ; Europe/ethnology

المؤلفون: Sarnowski C; Department of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA. Electronic address: chloesar@bu.edu., Leong A; Division of General Internal Medicine, Massachusetts General Hospital, Boston 02114, MA USA; Department of Medicine, Harvard Medical School, Boston, MA 02115, USA; Programs in Metabolism and Medical & Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA. Electronic address: ASLEONG@partners.org., Raffield LM; Department of Genetics, University of North Carolina, Chapel Hill, NC 27514, USA., Wu P; Department of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA., de Vries PS; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX 77030, USA., DiCorpo D; Department of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA., Guo X; Institute for Translational Genomics and Population Sciences, LABioMed and Department of Pediatrics at Harbor-UCLA Medical Center, Torrance, CA 90502, USA., Xu H; Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Liu Y; Department of Epidemiology & Prevention, Wake Forest School of Medicine, Winston-Salem, NC 27101, USA., Zheng X; Department of Biostatistics, University of Washington, Seattle, WA 98195, USA., Hu Y; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98108, USA., Brody JA; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA 98195, USA., Goodarzi MO; Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA., Hidalgo BA; University of Alabama at Birmingham, Department of Epidemiology, Birmingham, AL 35294, USA., Highland HM; Department of Epidemiology, UNC Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Jain D; Department of Biostatistics, University of Washington, Seattle, WA 98195, USA., Liu CT; Department of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA., Naik RP; Division of Hematology, Department of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA., O'Connell JR; University of Maryland School of Medicine, Baltimore, MD 21201, USA., Perry JA; University of Maryland School of Medicine, Baltimore, MD 21201, USA., Porneala BC; Division of General Internal Medicine, Massachusetts General Hospital, Boston 02114, MA USA., Selvin E; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA., Wessel J; Department of Epidemiology, Indiana University Fairbanks School of Public Health, Indianapolis, IN 46202, USA; Department of Medicine and Diabetes Translational Research Center, Indiana University School of Medicine, Indianapolis, IN 46202, USA., Psaty BM; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA 98195, USA; Kaiser Permanente Washington Health Research Institute, Seattle, WA 98101, USA; Departments of Epidemiology and Health Services, University of Washington, Seattle, WA 98195, USA., Curran JE; Department of Human Genetics and South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX 78520, USA., Peralta JM; Department of Human Genetics and South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX 78520, USA., Blangero J; Department of Human Genetics and South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX 78520, USA., Kooperberg C; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98108, USA., Mathias R; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA; GeneSTAR Research Program, Department of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA., Johnson AD; National Heart, Lung, and Blood Institute and Boston University's Framingham Heart Study, Framingham MA 01702, USA; Population Sciences Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20814, USA., Reiner AP; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98108, USA; Department of Epidemiology, University of Washington, Seattle, WA 98195, USA., Mitchell BD; Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA; Geriatrics Research and Education Clinical Center, Baltimore Veterans Administration Medical Center, Baltimore, MD 21201, USA., Cupples LA; Department of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA; National Heart, Lung, and Blood Institute and Boston University's Framingham Heart Study, Framingham MA 01702, USA., Vasan RS; National Heart, Lung, and Blood Institute and Boston University's Framingham Heart Study, Framingham MA 01702, USA; Section of Preventive Medicine and Epidemiology, Evans Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA; Whitaker Cardiovascular Institute and Cardiology Section, Evans Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA., Correa A; Departments of Medicine, Pediatrics, and Population Health Science, University of Mississippi Medical Center, Jackson, MS 39216, USA; The Jackson Heart Study, Jackson, MS 39213, USA., Morrison AC; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX 77030, USA., Boerwinkle E; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX 77030, USA; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA., Rotter JI; Institute for Translational Genomics and Population Sciences, LABioMed and Department of Pediatrics at Harbor-UCLA Medical Center, Torrance, CA 90502, USA., Rich SS; Center for Public Health Genomics, University of Virginia, Charlottesville, VA 22908, USA., Manning AK; Division of General Internal Medicine, Massachusetts General Hospital, Boston 02114, MA USA; Department of Medicine, Harvard Medical School, Boston, MA 02115, USA; Programs in Metabolism and Medical & Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Dupuis J; Department of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA; National Heart, Lung, and Blood Institute and Boston University's Framingham Heart Study, Framingham MA 01702, USA., Meigs JB; Division of General Internal Medicine, Massachusetts General Hospital, Boston 02114, MA USA; Department of Medicine, Harvard Medical School, Boston, MA 02115, USA; Programs in Metabolism and Medical & Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.

مؤلفون مشاركون: TOPMed Diabetes Working Group, TOPMed Hematology Working Group, TOPMed Hemostasis Working Group, National Heart, Lung, and Blood Institute TOPMed Consortium

المصدر: American journal of human genetics [Am J Hum Genet] 2019 Oct 03; Vol. 105 (4), pp. 706-718. Date of Electronic Publication: 2019 Sep 26.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 0370475 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1537-6605 (Electronic) Linking ISSN: 00029297 NLM ISO Abbreviation: Am J Hum Genet Subsets: MEDLINE

مواضيع طبية MeSH: Genetic Variation* , Precision Medicine*, Diabetes Mellitus/*diagnosis , Diabetes Mellitus/*genetics , Glycated Hemoglobin/*genetics , Population Groups/*genetics, Cohort Studies ; Female ; Humans ; Male ; Polymorphism, Single Nucleotide

المؤلفون: Wessel J; 1] Department of Epidemiology, Fairbanks School of Public Health, Indianapolis, Indiana 46202, USA [2] Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA., Chu AY; 1] Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts 02215, USA [2] National Heart, Lung, and Blood Institute (NHLBI) Framingham Heart Study, Framingham, Massachusetts 01702, USA., Willems SM; 1] Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam 3000 CE, The Netherlands [2] MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge CB2 0SL, UK., Wang S; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts 02118, USA., Yaghootkar H; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter EX1 2LU, UK., Brody JA; 1] Cardiovascular Health Research Unit, University of Washington, Seattle, Washington 98101, USA [2] Department of Medicine, University of Washington, Seattle, Washington 98195, USA., Dauriz M; 1] Massachusetts General Hospital, General Medicine Division, Boston, Massachusetts 02114, USA [2] Department of Medicine, Harvard Medical School, Boston, Massachusetts 02115, USA [3] Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Verona Medical School and Hospital Trust of Verona, Verona 37126, Italy., Hivert MF; 1] Harvard Pilgrim Health Care Institute, Department of Population Medicine, Harvard Medical School, Boston, Massachusetts 02215, USA [2] Division of Endocrinology and Metabolism, Department of Medicine, Université de Sherbrooke, Sherbrooke, Québec, Canada J1K 2R1 [3] Diabetes Unit, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA., Raghavan S; 1] Massachusetts General Hospital, General Medicine Division, Boston, Massachusetts 02114, USA [2] Department of Medicine, Harvard Medical School, Boston, Massachusetts 02115, USA., Lipovich L; 1] Center for Molecular Medicine and Genetics, Wayne State University, Detroit, Michigan 48201, USA [2] Department of Neurology, Wayne State University School of Medicine, Detroit, Michigan 48202, USA., Hidalgo B; Department of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama 35233, USA., Fox K; 1] Department of Medicine, University of Washington, Seattle, Washington 98195, USA [2] Department of Genome Sciences, University of Washington, Seattle, Washington 98195, USA., Huffman JE; 1] National Heart, Lung, and Blood Institute (NHLBI) Framingham Heart Study, Framingham, Massachusetts 01702, USA [2] MRC Human Genetics Unit, MRC IGMM, University of Edinburgh, Edinburgh, Scotland EH4 2XU, UK., An P; Division of Statistical Genomics and Department of Genetics, Washington University School of Medicine, St. Louis, Missouri 63108, USA., Lu Y; 1] The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA [2] The Genetics of Obesity and Related Metabolic Traits Program, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Rasmussen-Torvik LJ; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA., Grarup N; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen DK-2200, Denmark., Ehm MG; Quantitative Sciences, PCPS, GlaxoSmithKline, North Carolina 27709, USA., Li L; Quantitative Sciences, PCPS, GlaxoSmithKline, North Carolina 27709, USA., Baldridge AS; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA., Stančáková A; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio FI-70211, Finland., Abrol R; 1] Department of Medicine and Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California 90048, USA [2] Materials and Process Simulation Center, California Institute of Technology, Pasadena, California 91125, USA., Besse C; CEA, Institut de Génomique, Centre National de Génotypage, 2 Rue Gaston Crémieux, EVRY Cedex 91057, France., Boland A; CEA, Institut de Génomique, Centre National de Génotypage, 2 Rue Gaston Crémieux, EVRY Cedex 91057, France., Bork-Jensen J; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen DK-2200, Denmark., Fornage M; Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center, Houston, Texas 77030, USA., Freitag DF; 1] The Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK [2] Department of Public Health and Primary Care, Strangeways Research Laboratory, University of Cambridge, Cambridge CB1 8RN, UK., Garcia ME; Intramural Research Program, National Institute on Aging, Bethesda, Maryland 21224, USA., Guo X; Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California 90502, USA., Hara K; 1] The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA [2] The Genetics of Obesity and Related Metabolic Traits Program, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Isaacs A; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam 3000 CE, The Netherlands., Jakobsdottir J; Icelandic Heart Association, Holtasmari 1, Kopavogur IS-201, Iceland., Lange LA; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA., Layton JC; Indiana University, Fairbanks School of Public Health, Indianapolis, Indiana 46202, USA., Li M; Department of Epidemiology, Johns Hopkins University, Baltimore, Maryland 21205, USA., Hua Zhao J; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge CB2 0SL, UK., Meidtner K; Department of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal DE-14558, Germany., Morrison AC; Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston, Houston, Texas 77225, USA., Nalls MA; Laboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland 20892, USA., Peters MJ; 1] Department of Internal Medicine, Erasmus University Medical Center, Rotterdam 3000 CE, The Netherlands [2] The Netherlands Genomics Initiative-sponsored Netherlands Consortium for Healthy Aging (NGI-NCHA), Leiden/Rotterdam 2300 RC, The Netherlands., Sabater-Lleal M; Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm SE-171 77, Sweden., Schurmann C; 1] The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA [2] The Genetics of Obesity and Related Metabolic Traits Program, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Silveira A; Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm SE-171 77, Sweden., Smith AV; 1] Icelandic Heart Association, Holtasmari 1, Kopavogur IS-201, Iceland [2] University of Iceland, Reykjavik IS-101, Iceland., Southam L; 1] The Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK [2] Wellcome Trust Centre for Human Genetics, Oxford OX3 7BN, UK., Stoiber MH; Department of Genome Dynamics, Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA., Strawbridge RJ; Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm SE-171 77, Sweden., Taylor KD; Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California 90502, USA., Varga TV; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Skåne University Hospital, Malmö SE-205 02, Sweden., Allin KH; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen DK-2200, Denmark., Amin N; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam 3000 CE, The Netherlands., Aponte JL; Quantitative Sciences, PCPS, GlaxoSmithKline, North Carolina 27709, USA., Aung T; 1] Singapore Eye Research Institute, Singapore National Eye Centre, Singapore 168751, Singapore [2] Department of Ophthalmology, National University of Singapore and National University Health System, Singapore 119228, Singapore., Barbieri C; Division of Genetics and Cell Biology, San Raffaele Research Institute, Milano 20132, Italy., Bihlmeyer NA; 1] Predoctoral Training Program in Human Genetics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Maryland 21205, USA [2] McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA., Boehnke M; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan 48109, USA., Bombieri C; Section of Biology and Genetics, Department of Life and Reproduction Sciences, University of Verona, Verona 37100, Italy., Bowden DW; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, North Carolina 27157, USA., Burns SM; Diabetes Unit, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA., Chen Y; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts 02118, USA., Chen YD; Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California 90502, USA., Cheng CY; 1] Singapore Eye Research Institute, Singapore National Eye Centre, Singapore 168751, Singapore [2] Department of Ophthalmology, National University of Singapore and National University Health System, Singapore 119228, Singapore [3] Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore 119228, Singapore [4] Office of Clinical Sciences, Duke-NUS Graduate Medical School, National University of Singapore, Singapore 169857, Singapore., Correa A; Department of Medicine, University of Mississippi Medical Center, Jackson, Mississippi 39216, USA., Czajkowski J; Division of Statistical Genomics and Department of Genetics, Washington University School of Medicine, St. Louis, Missouri 63108, USA., Dehghan A; Department of Epidemiology, Erasmus University Medical Center, Rotterdam 3000 CE, The Netherlands., Ehret GB; 1] McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University, Baltimore, Maryland 21205, USA [2] Division of Cardiology, Geneva University Hospital Geneva 1211, Switzerland., Eiriksdottir G; Icelandic Heart Association, Holtasmari 1, Kopavogur IS-201, Iceland., Escher SA; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Skåne University Hospital, Malmö SE-205 02, Sweden., Farmaki AE; Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens 17671, Greece., Frånberg M; 1] Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm SE-171 77, Sweden [2] Department of Numerical Analysis and Computer Science, SciLifeLab, Stockholm University, Stockholm SE-106 91, Sweden., Gambaro G; Division of Nephrology, Department of Internal Medicine and Medical Specialties, Columbus-Gemelli University Hospital, Catholic University, Rome 00168, Italy., Giulianini F; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts 02215, USA., Goddard WA 3rd; Materials and Process Simulation Center, California Institute of Technology, Pasadena, California 91125, USA., Goel A; Department of Cardiovascular Medicine, The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., Gottesman O; The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Grove ML; Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston, Houston, Texas 77225, USA., Gustafsson S; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala SE-751 85, Sweden., Hai Y; Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California 90502, USA., Hallmans G; Department of Biobank Research, Umeå University, Umeå SE-901 87, Sweden., Heo J; Department of Biomedical Technology, Sangmyung University, Chungnam 330-720, Korea., Hoffmann P; 1] Institute of Human Genetics, Department of Genomics, Life &Brain Center, University of Bonn, Bonn DE-53127, Germany [2] Human Genomics Research Group, Division of Medical Genetics, University Hospital Basel Department of Biomedicine 4031, Basel, Switzerland [3] Institute of Neuroscience and Medicine (INM-1) Genomic Imaging Research Center Juelich, Juelich DE-52425, Germany., Ikram MK; 1] Singapore Eye Research Institute, Singapore National Eye Centre, Singapore 168751, Singapore [2] Office of Clinical Sciences, Duke-NUS Graduate Medical School, National University of Singapore, Singapore 169857, Singapore [3] Memory Aging &Cognition Centre (MACC), National University Health System, Singapore 117599, Singapore., Jensen RA; 1] Cardiovascular Health Research Unit, University of Washington, Seattle, Washington 98101, USA [2] Department of Medicine, University of Washington, Seattle, Washington 98195, USA., Jørgensen ME; Steno Diabetes Center, Gentofte DK-2820, Denmark., Jørgensen T; 1] Research Centre for Prevention and Health, Glostrup University Hospital, Glostrup DK-2600, Denmark [2] Faculty of Medicine, University of Aalborg, Aalborg DK-9220, Denmark., Karaleftheri M; Echinos Medical Centre, Echinos 67300, Greece., Khor CC; 1] Department of Ophthalmology, National University of Singapore and National University Health System, Singapore 119228, Singapore [2] Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore 119228, Singapore [3] Division of Human Genetics, Genome Institute of Singapore, Singapore 138672, Singapore., Kirkpatrick A; Materials and Process Simulation Center, California Institute of Technology, Pasadena, California 91125, USA., Kraja AT; Division of Statistical Genomics and Department of Genetics, Washington University School of Medicine, St. Louis, Missouri 63108, USA., Kuusisto J; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio FI-70211, Finland., Lange EM; 1] Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA [2] Department of Biostatistics, University of North Carolina, Chapel Hill, North Carolina 27599, USA., Lee IT; 1] Division of Endocrine and Metabolism, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung 407, Taiwan [2] School of Medicine, National Yang-Ming University, Taipei 112, Taiwan., Lee WJ; Department of Medical Research, Taichung Veterans General Hospital, Taichung 407, Taiwan., Leong A; 1] Massachusetts General Hospital, General Medicine Division, Boston, Massachusetts 02114, USA [2] Department of Medicine, Harvard Medical School, Boston, Massachusetts 02115, USA., Liao J; 1] Singapore Eye Research Institute, Singapore National Eye Centre, Singapore 168751, Singapore [2] Department of Ophthalmology, National University of Singapore and National University Health System, Singapore 119228, Singapore., Liu C; National Heart, Lung, and Blood Institute (NHLBI) Framingham Heart Study, Framingham, Massachusetts 01702, USA., Liu Y; Department of Epidemiology &Prevention, Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina 27106, USA., Lindgren CM; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., Linneberg A; 1] Research Centre for Prevention and Health, Glostrup University Hospital, Glostrup DK-2600, Denmark [2] Department of Clinical Experimental Research, Copenhagen University Hospital Glostrup, Glostrup DK-2600, Denmark [3] Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen DK-2200, Denmark., Malerba G; Section of Biology and Genetics, Department of Life and Reproduction Sciences, University of Verona, Verona 37100, Italy., Mamakou V; 1] National and Kapodistrian University of Athens, Faculty of Medicine, Athens 115 27, Greece [2] Dromokaiteio Psychiatric Hospital, Athens 124 61, Greece., Marouli E; Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens 17671, Greece., Maruthur NM; 1] Division of General Internal Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA [2] Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins University, Baltimore, Maryland 21205, USA., Matchan A; The Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK., McKean-Cowdin R; Department of Preventive Medicine, Keck School of Medicine of the University of Southern California, Los Angeles 90033, USA., McLeod O; Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm SE-171 77, Sweden., Metcalf GA; Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas 77030, USA., Mohlke KL; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA., Muzny DM; Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas 77030, USA., Ntalla I; 1] Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens 17671, Greece [2] University of Leicester, Leicester LE1 7RH, UK., Palmer ND; 1] Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, North Carolina 27157, USA [2] Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston-Salem, North Carolina 27106, USA., Pasko D; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter EX1 2LU, UK., Peter A; 1] Department of Internal Medicine, Division of Endocrinology, Metabolism, Pathobiochemistry and Clinical Chemistry and Institute of Diabetes Research and Metabolic Diseases, University of Tübingen, Tübingen DE-72076, Germany [2] German Center for Diabetes Research (DZD), Neuherberg DE-85764, Germany., Rayner NW; 1] The Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK [2] Wellcome Trust Centre for Human Genetics, Oxford OX3 7BN, UK [3] The Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford OX3 7LE, UK., Renström F; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Skåne University Hospital, Malmö SE-205 02, Sweden., Rice K; 1] Cardiovascular Health Research Unit, University of Washington, Seattle, Washington 98101, USA [2] Department of Biostatistics, University of Washington, Seattle, Washington 98195, USA., Sala CF; Division of Genetics and Cell Biology, San Raffaele Research Institute, Milano 20132, Italy., Sennblad B; 1] Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm SE-171 77, Sweden [2] Science for Life Laboratory, Karolinska Institutet, Stockholm SE-171 77, Sweden., Serafetinidis I; Department of Gastroenterology, Gennimatas General Hospital, Athens 11527, Greece., Smith JA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan 48109, USA., Soranzo N; 1] The Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK [2] Department of Hematology, Long Road, Cambridge CB2 0XY, UK., Speliotes EK; Department of Internal Medicine, Division of Gastroenterology and Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan 48109, USA., Stahl EA; Division of Psychiatric Genomics, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Stirrups K; 1] The Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK [2] William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London E1 4NS, UK., Tentolouris N; First Department of Propaedeutic and Internal Medicine, Athens University Medical School, Laiko General Hospital, Athens 11527, Greece., Thanopoulou A; Diabetes Centre, 2nd Department of Internal Medicine, National University of Athens, Hippokration General Hospital, Athens 11527, Greece., Torres M; Department of Preventive Medicine, Keck School of Medicine of the University of Southern California, Los Angeles 90033, USA., Traglia M; Division of Genetics and Cell Biology, San Raffaele Research Institute, Milano 20132, Italy., Tsafantakis E; Anogia Medical Centre, Anogia 740 51, Greece., Javad S; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge CB2 0SL, UK., Yanek LR; The GeneSTAR Research Program, Division of General Internal Medicine, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA., Zengini E; 1] Dromokaiteio Psychiatric Hospital, Athens 124 61, Greece [2] University of Sheffield, Sheffield S10 2TN, UK., Becker DM; The GeneSTAR Research Program, Division of General Internal Medicine, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA., Bis JC; 1] Cardiovascular Health Research Unit, University of Washington, Seattle, Washington 98101, USA [2] Department of Medicine, University of Washington, Seattle, Washington 98195, USA., Brown JB; 1] Department of Genome Dynamics, Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA [2] Department of Statistics, University of California at Berkeley, Berkeley, California 94720, USA., Cupples LA; 1] National Heart, Lung, and Blood Institute (NHLBI) Framingham Heart Study, Framingham, Massachusetts 01702, USA [2] Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts 02118, USA., Hansen T; 1] The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen DK-2200, Denmark [2] Faculty of Health Science, University of Copenhagen, Copenhagen 1165, Denmark., Ingelsson E; 1] Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala SE-751 85, Sweden [2] Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., Karter AJ; Division of Research, Kaiser Permanente, Northern California Region, Oakland, California 94612, USA., Lorenzo C; Department of Medicine, University of Texas Health Science Center, San Antonio, Texas 77030, USA., Mathias RA; The GeneSTAR Research Program, Division of General Internal Medicine, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA., Norris JM; Department of Epidemiology, Colorado School of Public Health, University of Colorado Denver, Aurora, Colorado 80204, USA., Peloso GM; 1] Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts 02142, USA [2] Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts 02114, USA., Sheu WH; 1] Division of Endocrine and Metabolism, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung 407, Taiwan [2] School of Medicine, National Yang-Ming University, Taipei 112, Taiwan [3] College of Medicine, National Defense Medical Center, Taipei 114, Taiwan., Toniolo D; Division of Genetics and Cell Biology, San Raffaele Research Institute, Milano 20132, Italy., Vaidya D; The GeneSTAR Research Program, Division of General Internal Medicine, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA., Varma R; Department of Preventive Medicine, Keck School of Medicine of the University of Southern California, Los Angeles 90033, USA., Wagenknecht LE; Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina 27106, USA., Boeing H; Department of Epidemiology, German Institute of Human Nutrition Potsdam Rehbrücke, Nuthetal DE-14558, Germany., Bottinger EP; The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Dedoussis G; Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens 17671, Greece., Deloukas P; 1] William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London E1 4NS, UK [2] Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK [3] Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, Jeddah 22254, Saudi Arabia., Ferrannini E; CNR Institute of Clinical Physiology, Pisa 73100, Italy., Franco OH; Department of Epidemiology, Erasmus University Medical Center, Rotterdam 3000 CE, The Netherlands., Franks PW; 1] Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Skåne University Hospital, Malmö SE-205 02, Sweden [2] Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA [3] Department of Public Health &Clinical Medicine, Umeå University, Umeå SE-901 87, Sweden., Gibbs RA; Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas 77030, USA., Gudnason V; 1] Icelandic Heart Association, Holtasmari 1, Kopavogur IS-201, Iceland [2] University of Iceland, Reykjavik IS-101, Iceland., Hamsten A; Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm SE-171 77, Sweden., Harris TB; Intramural Research Program, National Institute on Aging, Bethesda, Maryland 21224, USA., Hattersley AT; Genetics of Diabetes, University of Exeter Medical School, University of Exeter, Exeter EX1 2LU, UK., Hayward C; MRC Human Genetics Unit, MRC IGMM, University of Edinburgh, Edinburgh, Scotland EH4 2XU, UK., Hofman A; Department of Epidemiology, Erasmus University Medical Center, Rotterdam 3000 CE, The Netherlands., Jansson JH; 1] Department of Public Health &Clinical Medicine, Umeå University, Umeå SE-901 87, Sweden [2] Research Unit, Skellefteå SE-931 87, Sweden., Langenberg C; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge CB2 0SL, UK., Launer LJ; Intramural Research Program, National Institute on Aging, Bethesda, Maryland 21224, USA., Levy D; 1] Population Sciences Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892, USA [2] Framingham Heart Study, Framingham, Massachusetts 01702, USA., Oostra BA; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam 3000 CE, The Netherlands., O'Donnell CJ; 1] National Heart, Lung, and Blood Institute (NHLBI) Framingham Heart Study, Framingham, Massachusetts 01702, USA [2] Department of Medicine, Harvard Medical School, Boston, Massachusetts 02115, USA [3] Cardiology Division, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA., O'Rahilly S; University of Cambridge Metabolic Research Laboratories, MRC Metabolic Diseases Unit and NIHR Cambridge Biomedical Research Centre, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge CB2 1TN, UK., Padmanabhan S; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow G12 8TA, UK., Pankow JS; Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, Minnesota 55455, USA., Polasek O; Department of Public Health, Faculty of Medicine, University of Split, Split 21000, Croatia., Province MA; Division of Statistical Genomics and Department of Genetics, Washington University School of Medicine, St. Louis, Missouri 63108, USA., Rich SS; Center for Public Health Genomics, Department of Public Health Sciences, University of Virginia, Charlottesville, Virginia 22908, USA., Ridker PM; 1] Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts 02215, USA [2] Division of Cardiology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA., Rudan I; Centre for Population Health Sciences, Medical School, University of Edinburgh, Edinburgh, Scotland EH8 9YL, UK., Schulze MB; 1] Department of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal DE-14558, Germany [2] German Center for Diabetes Research (DZD), Neuherberg DE-85764, Germany., Smith BH; Medical Research Institute, University of Dundee, Dundee DD1 9SY, UK., Uitterlinden AG; 1] Department of Internal Medicine, Erasmus University Medical Center, Rotterdam 3000 CE, The Netherlands [2] Department of Epidemiology, Erasmus University Medical Center, Rotterdam 3000 CE, The Netherlands., Walker M; Institute of Cellular Medicine, Newcastle University, Newcastle-upon-Tyne NE1 7RU, UK., Watkins H; Department of Cardiovascular Medicine, The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., Wong TY; 1] Singapore Eye Research Institute, Singapore National Eye Centre, Singapore 168751, Singapore [2] Department of Ophthalmology, National University of Singapore and National University Health System, Singapore 119228, Singapore [3] Office of Clinical Sciences, Duke-NUS Graduate Medical School, National University of Singapore, Singapore 169857, Singapore., Zeggini E; The Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK., Laakso M; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio FI-70211, Finland., Borecki IB; Division of Statistical Genomics and Department of Genetics, Washington University School of Medicine, St. Louis, Missouri 63108, USA., Chasman DI; 1] Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts 02215, USA [2] Division of Genetics, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA., Pedersen O; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen DK-2200, Denmark., Psaty BM; 1] Cardiovascular Health Research Unit, University of Washington, Seattle, Washington 98101, USA [2] Department of Medicine, University of Washington, Seattle, Washington 98195, USA [3] Department of Epidemiology, University of Washington, Seattle, Washington 98195, USA [4] Department of Health Services, University of Washington, Seattle, Washington 98195, USA [5] Group Health Research Institute, Group Health Cooperative, Seattle, Washington 98195, USA., Tai ES; 1] Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore 119228, Singapore [2] Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore., van Duijn CM; 1] Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam 3000 CE, The Netherlands [2] Center for Medical Systems Biology, Leiden 2300, The Netherlands., Wareham NJ; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge CB2 0SL, UK., Waterworth DM; Genetics, PCPS, GlaxoSmithKline, Philadelphia, Pennsylvania 19104, USA., Boerwinkle E; 1] Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston, Houston, Texas 77225, USA [2] Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas 77030, USA., Kao WH; 1] Department of Epidemiology, Johns Hopkins University, Baltimore, Maryland 21205, USA [2] Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins University, Baltimore, Maryland 21205, USA [3] Department of Medicine, Johns Hopkins University, Baltimore, Maryland 21205, USA., Florez JC; 1] Department of Medicine, Harvard Medical School, Boston, Massachusetts 02115, USA [2] Diabetes Unit, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA [3] Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts 02142, USA [4] Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts 02114, USA., Loos RJ; 1] The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA [2] The Genetics of Obesity and Related Metabolic Traits Program, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA [3] The Mindich Child Health and Development Institute, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Wilson JG; Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, Mississippi 38677, USA., Frayling TM; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter EX1 2LU, UK., Siscovick DS; 1] New York Academy of Medicine, New York, New York 10029, USA [2] Cardiovascular Health Research Unit, Departments of Medicine and Epidemiology, University of Washington, Seattle, Washington 98195, USA., Dupuis J; 1] National Heart, Lung, and Blood Institute (NHLBI) Framingham Heart Study, Framingham, Massachusetts 01702, USA [2] Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts 02118, USA., Rotter JI; Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California 90502, USA., Meigs JB; 1] Massachusetts General Hospital, General Medicine Division, Boston, Massachusetts 02114, USA [2] Department of Medicine, Harvard Medical School, Boston, Massachusetts 02115, USA., Scott RA; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge CB2 0SL, UK., Goodarzi MO; 1] Department of Medicine and Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California 90048, USA [2] Division of Endocrinology, Diabetes and Metabolism, Cedars-Sinai Medical Center, Los Angeles, California 90048, USA.

مؤلفون مشاركون: EPIC-InterAct Consortium

المصدر: Nature communications [Nat Commun] 2015 Jan 29; Vol. 6, pp. 5897. Date of Electronic Publication: 2015 Jan 29.

نوع المنشور: Journal Article; Research Support, American Recovery and Reinvestment Act; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Genetic Predisposition to Disease* , Genetic Variation* , Mutation Rate* , Oligonucleotide Array Sequence Analysis*, Blood Glucose/*metabolism , Diabetes Mellitus, Type 2/*genetics , Exome/*genetics , Fasting/*blood, Black People/genetics ; Diabetes Mellitus, Type 2/blood ; Genetic Association Studies ; Genetic Loci ; Glucagon-Like Peptide-1 Receptor/genetics ; Glucose-6-Phosphatase/genetics ; Humans ; Insulin/blood ; Polymorphism, Single Nucleotide/genetics ; White People/genetics

المؤلفون: Dybul M; Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA. mdybul@nih.gov, Daucher M, Jensen MA, Hallahan CW, Chun TW, Belson M, Hidalgo B, Nickle DC, Yoder C, Metcalf JA, Davey RT, Ehler L, Kress-Rock D, Nies-Kraske E, Liu S, Mullins JI, Fauci AS

المصدر: Journal of virology [J Virol] 2003 Mar; Vol. 77 (5), pp. 3229-37.

نوع المنشور: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

بيانات الدورية: Publisher: American Society For Microbiology Country of Publication: United States NLM ID: 0113724 Publication Model: Print Cited Medium: Print ISSN: 0022-538X (Print) Linking ISSN: 0022538X NLM ISO Abbreviation: J Virol Subsets: MEDLINE

مواضيع طبية MeSH: Genetic Variation*, Antiretroviral Therapy, Highly Active/*methods , HIV Infections/*drug therapy , HIV-1/*genetics, Drug Administration Schedule ; Genes, env/genetics ; HIV Infections/virology ; HIV-1/classification ; HIV-1/drug effects ; Heteroduplex Analysis ; Humans ; RNA, Viral/blood ; Recurrence ; Sequence Analysis, DNA ; Viral Load

المؤلفون: Sarnowski, Chloé, Leong, Aaron, Raffield, Laura M, Wu, Peitao, de Vries, Paul S, DiCorpo, Daniel, Guo, Xiuqing, Xu, Huichun, Liu, Yongmei, Zheng, Xiuwen, Hu, Yao, Brody, Jennifer A, Goodarzi, Mark O, Hidalgo, Bertha A, Highland, Heather M, Jain, Deepti, Liu, Ching-Ti, Naik, Rakhi P, O'Connell, Jeffrey R, Perry, James A, Porneala, Bianca C, Selvin, Elizabeth, Wessel, Jennifer, Psaty, Bruce M, Curran, Joanne E, Peralta, Juan M, Blangero, John, Kooperberg, Charles, Mathias, Rasika, Johnson, Andrew D, Reiner, Alexander P, Mitchell, Braxton D, Cupples, L Adrienne, Vasan, Ramachandran S, Correa, Adolfo, Morrison, Alanna C, Boerwinkle, Eric, Rotter, Jerome I, Rich, Stephen S, Manning, Alisa K, Dupuis, Josée, Meigs, James B, TOPMed Diabetes Working Group, TOPMed Hematology Working Group, TOPMed Hemostasis Working Group, National Heart, Lung, and Blood Institute TOPMed Consortium

المصدر: American journal of human genetics, vol 105, iss 4

مصطلحات موضوعية: Male, multi-ancestry sample, whole-genome sequence association analyses, Medical and Health Sciences, TOPMed Diabetes Working Group, Cohort Studies, Population Groups, Clinical Research, Diabetes Mellitus, Genetics, Humans, Polymorphism, Precision Medicine, Lung, hemoglobin A1c, TOPMed Hematology Working Group, Metabolic and endocrine, Glycated Hemoglobin, Genetics & Heredity, Prevention, Diabetes, Genetic Variation, National Heart, Single Nucleotide, The Trans-Omics for Precision Medicine (TOPMed) program, Biological Sciences, TOPMed Hemostasis Working Group, Good Health and Well Being, and Blood Institute TOPMed Consortium, Female

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https://escholarship.org/uc/item/3f89c2nn

المؤلفون: de Vasconcellos, Jaira Ferreira, Abedalthagafi, Malak, Calo, Silvia, Dajani, Rana, Dlamini, Zodwa, Hidalgo, Bertha, Le Goff, Carine, Vasanthakumar, Aparna

المصدر: Frontiers in Genetics; 10/3/2022, Vol. 13, p1-2, 3p

مصطلحات موضوعية: WOMEN in science, GENOME-wide association studies, GENETIC variation

المؤلفون: Wessel, Jennifer, Chu, Audrey Y, Willems, Sara M, Wang, Shuai, Yaghootkar, Hanieh, Brody, Jennifer A, Dauriz, Marco, Hivert, Marie-France, Raghavan, Sridharan, Lipovich, Leonard, Hidalgo, Bertha, Fox, Keolu, Huffman, Jennifer E, An, Ping, Lu, Yingchang, Rasmussen-Torvik, Laura J, Grarup, Niels, Ehm, Margaret G, Li, Li, Baldridge, Abigail S, Stančáková, Alena, Abrol, Ravinder, Besse, Céline, Boland, Anne, Bork-Jensen, Jette, Fornage, Myriam, Freitag, Daniel F, Garcia, Melissa E, Guo, Xiuqing, Hara, Kazuo, Isaacs, Aaron, Jakobsdottir, Johanna, Lange, Leslie A, Layton, Jill C, Li, Man, Hua Zhao, Jing, Meidtner, Karina, Morrison, Alanna C, Nalls, Mike A, Peters, Marjolein J, Sabater-Lleal, Maria, Schurmann, Claudia, Silveira, Angela, Smith, Albert V, Southam, Lorraine, Stoiber, Marcus H, Strawbridge, Rona J, Taylor, Kent D, Varga, Tibor V, Allin, Kristine H, Amin, Najaf, Aponte, Jennifer L, Aung, Tin, Barbieri, Caterina, Bihlmeyer, Nathan A, Boehnke, Michael, Bombieri, Cristina, Bowden, Donald W, Burns, Sean M, Chen, Yuning, Chen, Yii-DerI, Cheng, Ching-Yu, Correa, Adolfo, Czajkowski, Jacek, Dehghan, Abbas, Ehret, Georg B, Eiriksdottir, Gudny, Escher, Stefan A, Farmaki, Aliki-Eleni, Frånberg, Mattias, Gambaro, Giovanni, Giulianini, Franco, Goddard, William A, Goel, Anuj, Gottesman, Omri, Grove, Megan L, Gustafsson, Stefan, Hai, Yang, Hallmans, Göran, Heo, Jiyoung, Hoffmann, Per, Ikram, Mohammad K, Jensen, Richard A, Jørgensen, Marit E, Jørgensen, Torben, Karaleftheri, Maria, Khor, Chiea C, Kirkpatrick, Andrea, Kraja, Aldi T, Kuusisto, Johanna, Lange, Ethan M, Lee, IT, Lee, Wen-Jane, Leong, Aaron, Liao, Jiemin, Liu, Chunyu, Liu, Yongmei, Lindgren, Cecilia M, Linneberg, Allan, Malerba, Giovanni

المصدر: Nature communications, vol 6, iss 1

مصطلحات موضوعية: Blood Glucose, European Continental Ancestry Group, Black People, Metabolic and Endocrine, White People, Glucagon-Like Peptide-1 Receptor, Mutation Rate, Clinical Research, Diabetes Mellitus, Genetics, Humans, Insulin, 2.1 Biological and endogenous factors, Genetic Predisposition to Disease, Exome, Aetiology, Polymorphism, Genetic Association Studies, Oligonucleotide Array Sequence Analysis, African Continental Ancestry Group, Nutrition, Prevention, Diabetes, Human Genome, Genetic Variation, Fasting, Single Nucleotide, Genetic Loci, Glucose-6-Phosphatase, EPIC-InterAct Consortium, Type 2

وصف الملف: application/pdf

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https://escholarship.org/uc/item/8rr9g67v