المؤلفون: Guggino WB; Departments of Medicine and Physiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Yanda MK; Departments of Medicine and Physiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Cebotaru CV; Departments of Medicine and Physiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Cebotaru L; Departments of Medicine and Physiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

المصدر: Human gene therapy [Hum Gene Ther] 2020 Sep; Vol. 31 (17-18), pp. 1010-1023.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: M.A. Liebert Country of Publication: United States NLM ID: 9008950 Publication Model: Print Cited Medium: Internet ISSN: 1557-7422 (Electronic) Linking ISSN: 10430342 NLM ISO Abbreviation: Hum Gene Ther Subsets: MEDLINE

مواضيع طبية MeSH: Transduction, Genetic*, Cystic Fibrosis/*therapy , Cystic Fibrosis Transmembrane Conductance Regulator/*genetics , Dependovirus/*genetics , Genetic Vectors/*administration & dosage , Lung/*metabolism, Animals ; Cystic Fibrosis/genetics ; Cystic Fibrosis/immunology ; Dose-Response Relationship, Drug ; Gene Transfer Techniques ; Genetic Therapy ; Genetic Vectors/genetics ; Genome, Viral ; Humans ; Lung/immunology ; Lung/pathology ; Macaca mulatta

المؤلفون: Schuster BS; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; Center for Nanomedicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Kim AJ; Center for Nanomedicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; Current address: Departments of Neurosurgery and Pharmaceutical Sciences, University of Maryland, Baltimore, Baltimore, Maryland, USA., Kays JC; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; Center for Nanomedicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Kanzawa MM; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; Center for Nanomedicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Guggino WB; Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Boyle MP; Division of Pulmonary and Critical Care Medicine, Johns Hopkins Adult Cystic Fibrosis Program, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Rowe SM; Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA., Muzyczka N; Department of Molecular Genetics and Microbiology, and Powell Gene Therapy Center, University of Florida College of Medicine, Gainesville, Florida, USA., Suk JS; Center for Nanomedicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Hanes J; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; Center for Nanomedicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; Institute for NanoBioTechnology, Johns Hopkins University, Baltimore, Maryland, USA. Electronic address: hanes@jhmi.edu.

المصدر: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2014 Aug; Vol. 22 (8), pp. 1484-1493. Date of Electronic Publication: 2014 May 29.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 100890581 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-0024 (Electronic) Linking ISSN: 15250016 NLM ISO Abbreviation: Mol Ther Subsets: MEDLINE

مواضيع طبية MeSH: Cystic Fibrosis/*virology , Dependovirus/*physiology , Genetic Vectors/*therapeutic use , Sputum/*virology, Acetylcysteine/pharmacology ; Cell Line ; Cystic Fibrosis/therapy ; Dependovirus/classification ; Dependovirus/genetics ; Genetic Therapy ; HEK293 Cells ; Humans ; Microscopy, Electron, Scanning ; Sputum/drug effects

المؤلفون: Lassance RM; Laboratory of Cellular and Molecular Physiology, University of Rio de Janeiro, Centro de Ciências da Saúde, Ilha do Fundão, 21949-900 Rio de Janeiro, Brazil., Pássaro CP, Martini SV, Castiglione RC, Gutierrez TM, Abreu SC, Antunes MA, Xisto DG, Cebotaru L, Petrs-Silva H, Zin WA, Guggino WB, Linden R, Rocco PR, Morales MM

المصدر: Respiratory physiology & neurobiology [Respir Physiol Neurobiol] 2008 Jan 01; Vol. 160 (1), pp. 91-8. Date of Electronic Publication: 2007 Sep 14.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 101140022 Publication Model: Print-Electronic Cited Medium: Print ISSN: 1569-9048 (Print) Linking ISSN: 15699048 NLM ISO Abbreviation: Respir Physiol Neurobiol Subsets: MEDLINE

مواضيع طبية MeSH: Dependovirus/*genetics , Genetic Therapy/*adverse effects , Genetic Vectors/*adverse effects , Lung/*physiology, Animals ; Apoptosis/drug effects ; Bronchodilator Agents/pharmacology ; Green Fluorescent Proteins/genetics ; Immunohistochemistry ; Lung/pathology ; Methacholine Chloride/pharmacology ; Mice ; Mice, Inbred BALB C ; RNA/genetics ; RNA/isolation & purification ; RNA, Messenger/biosynthesis ; RNA, Messenger/genetics ; Respiratory Mechanics/physiology ; Reverse Transcriptase Polymerase Chain Reaction

المؤلفون: Fischer AC; Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Smith CI, Cebotaru L, Zhang X, Askin FB, Wright J, Guggino SE, Adams RJ, Flotte T, Guggino WB

المصدر: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2007 Apr; Vol. 15 (4), pp. 756-63. Date of Electronic Publication: 2007 Feb 13.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 100890581 Publication Model: Print-Electronic Cited Medium: Print ISSN: 1525-0016 (Print) Linking ISSN: 15250016 NLM ISO Abbreviation: Mol Ther Subsets: MEDLINE

مواضيع طبية MeSH: Genetic Vectors*, Cystic Fibrosis Transmembrane Conductance Regulator/*genetics , Dependovirus/*genetics, Animals ; Base Sequence ; Cystic Fibrosis/genetics ; Cystic Fibrosis/therapy ; DNA Primers/genetics ; Dependovirus/classification ; Gene Expression ; Genetic Therapy/methods ; Green Fluorescent Proteins/genetics ; Macaca mulatta ; Peptide Fragments/genetics ; Recombinant Proteins/genetics ; Transfection

المؤلفون: Sirninger J; Powell Gene Therapy Center, UF Genetics Institute, Department of Pediatrics and Molecular Genetics and Microbiology, University of Florida College of Medicine, Gainesville, FL 32619-0296, USA., Muller C, Braag S, Tang Q, Yue H, Detrisac C, Ferkol T, Guggino WB, Flotte TR

المصدر: Human gene therapy [Hum Gene Ther] 2004 Sep; Vol. 15 (9), pp. 832-41.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

بيانات الدورية: Publisher: M.A. Liebert Country of Publication: United States NLM ID: 9008950 Publication Model: Print Cited Medium: Print ISSN: 1043-0342 (Print) Linking ISSN: 10430342 NLM ISO Abbreviation: Hum Gene Ther Subsets: MEDLINE

مواضيع طبية MeSH: Genetic Vectors*, Cystic Fibrosis/*therapy , Cystic Fibrosis Transmembrane Conductance Regulator/*genetics , Dependovirus/*genetics, Actins/genetics ; Animals ; Chloride Channels/drug effects ; Cloning, Molecular ; Cystic Fibrosis/genetics ; DNA, Recombinant/therapeutic use ; Dependovirus/metabolism ; Gene Expression ; Genetic Therapy ; Luciferases/analysis ; Luciferases/genetics ; Mice ; Pneumonia/microbiology ; Pneumonia/pathology ; Promoter Regions, Genetic ; Pseudomonas aeruginosa/pathogenicity ; Weight Loss

المؤلفون: Fischer AC; Department of Physiology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA., Beck SE, Smith CI, Laube BL, Askin FB, Guggino SE, Adams RJ, Flotte TR, Guggino WB

المصدر: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2003 Dec; Vol. 8 (6), pp. 918-26.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 100890581 Publication Model: Print Cited Medium: Print ISSN: 1525-0016 (Print) Linking ISSN: 15250016 NLM ISO Abbreviation: Mol Ther Subsets: MEDLINE

مواضيع طبية MeSH: Dependovirus* , Genetic Therapy* , Genetic Vectors*/administration & dosage, Aerosols/*administration & dosage, Animals ; Bronchi/metabolism ; Epithelium/metabolism ; Genes, Reporter ; Lung/pathology ; Macaca mulatta ; Time Factors ; Transgenes

المؤلفون: Flotte TR; Department of Pediatrics and Powell Gene Therapy Center, University of Florida, Gainesville, FL 32610-0296, USA. flotttr@peds.ufl.edu, Zeitlin PL, Reynolds TC, Heald AE, Pedersen P, Beck S, Conrad CK, Brass-Ernst L, Humphries M, Sullivan K, Wetzel R, Taylor G, Carter BJ, Guggino WB

المصدر: Human gene therapy [Hum Gene Ther] 2003 Jul 20; Vol. 14 (11), pp. 1079-88.

نوع المنشور: Clinical Trial; Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

بيانات الدورية: Publisher: M.A. Liebert Country of Publication: United States NLM ID: 9008950 Publication Model: Print Cited Medium: Print ISSN: 1043-0342 (Print) Linking ISSN: 10430342 NLM ISO Abbreviation: Hum Gene Ther Subsets: MEDLINE

مواضيع طبية MeSH: Cystic Fibrosis/*therapy , Cystic Fibrosis Transmembrane Conductance Regulator/*genetics , Dependovirus/*genetics , Genetic Vectors/*toxicity, Administration, Intranasal ; Adolescent ; Adult ; Antibodies, Viral/blood ; Bronchi ; Cystic Fibrosis/diagnosis ; Cystic Fibrosis/immunology ; DNA, Recombinant/genetics ; DNA, Viral/analysis ; Dependovirus/immunology ; Enzyme-Linked Immunosorbent Assay ; Genetic Vectors/administration & dosage ; Humans ; Interleukins/biosynthesis ; Male ; Viremia/diagnosis ; Virus Shedding

المؤلفون: Beck SE; Eudowood Division of Pediatric Respitarory Sciences and Departments of Pediatrics, and Physiology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA., Laube BL, Barberena CI, Fischer AC, Adams RJ, Chesnut K, Flotte TR, Guggino WB

المصدر: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2002 Oct; Vol. 6 (4), pp. 546-54.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 100890581 Publication Model: Print Cited Medium: Print ISSN: 1525-0016 (Print) Linking ISSN: 15250016 NLM ISO Abbreviation: Mol Ther Subsets: MEDLINE

مواضيع طبية MeSH: Dependovirus*, Genetic Vectors/*administration & dosage , Lung/*metabolism, Administration, Inhalation ; Animals ; DNA, Complementary/metabolism ; Genes, Reporter/genetics ; Genes, Reporter/physiology ; Genetic Vectors/genetics ; Macaca mulatta ; RNA, Messenger/metabolism

المؤلفون: Flotte, Terence R., Afione, Sandra A., Conrad, Carol, McGarth, Sharon A., Solow, Rikki, Oka, Hidemi, Zeitlin, Pamela L., Guggino, William B., Carter, Barrie J.

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 1993 Nov . 90(22), 10613-10617.

URL الوصول: https://www.jstor.org/stable/2363277

المؤلفون: Guggino, William B., Cebotaru, Liudmila

مصطلحات موضوعية: Cystic Fibrosis, Genetic Vectors, Animals, Cystic Fibrosis Transmembrane Conductance Regulator, Humans, Genetic Therapy, Dependovirus, Promoter Regions, Genetic, Article, Trans-Splicing

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::f5efd7f83f2aaa85ef3f1e959a3a6c8b
https://europepmc.org/articles/PMC5858933/