المؤلفون: Yusuke Kawashima, Shuichi Ohkubo, Hiroaki Ochiiwa, Naoko Hashimoto, Motoi Nishimura, Masataka Yokoyama, Guzhanuer Ailiken, Akitoshi Nakayama, Tomoaki Tanaka, Tomonori Haruma, Chihoko Yoshimura, Kazuyuki Yamagata, Hidekazu Nagano, Osamu Ohara, Kazutaka Murata, Keiji Ishida, Hiromi Muraoka

المصدر: Oncogene

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, NEDD8 Protein, Ubiquitin-Protein Ligases, CASP8 and FADD-Like Apoptosis Regulating Protein, Apoptosis, Article, CFLAR, Proto-Oncogene Proteins c-myc, Mice, 03 medical and health sciences, 0302 clinical medicine, Ubiquitin, Downregulation and upregulation, Cell Line, Tumor, hemic and lymphatic diseases, Genetics, Animals, Humans, Pyrroles, RNA-Seq, Enzyme Inhibitors, RNA, Small Interfering, Molecular Biology, Caspase, Haematological cancer, Caspase 8, biology, Myeloid leukemia, Xenograft Model Antitumor Assays, Cell biology, Leukemia, Myeloid, Acute, Pyrimidines, 030104 developmental biology, Proto-Oncogene Proteins c-bcl-2, 030220 oncology & carcinogenesis, biology.protein, Signal transduction, Chromatin immunoprecipitation, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe6fc711abd4a8709c668da5a91c6d63
https://doi.org/10.1038/s41388-020-01586-4

المؤلفون: Tomoaki Tanaka, Naoko Hashimoto

المصدر: Journal of human genetics. 62(2)

مصطلحات موضوعية: 0301 basic medicine, Untranslated region, Genetic Markers, medicine.medical_treatment, Type 2 diabetes, Biology, Bioinformatics, medicine.disease_cause, 03 medical and health sciences, Insulin-Secreting Cells, microRNA, Gene expression, Genetics, medicine, Diabetes Mellitus, Glucose homeostasis, Gene silencing, Humans, RNA, Messenger, Genetics (clinical), Insulin, medicine.disease, MicroRNAs, 030104 developmental biology, Gene Expression Regulation, Hyperglycemia, Cancer research, Insulin Resistance, Tumor Suppressor Protein p53, Carcinogenesis, Biomarkers, Genome-Wide Association Study

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d460ced74a7a7e0737ea1e3b7de2aed8
https://pubmed.ncbi.nlm.nih.gov/27928162

المؤلفون: Maki Koyanagi-Kimura, Ayumi Kanno, Yoshiaki Kido, Wataru Nishimura, Yuka Ihara, Kazuki Yasuda, Nobuya Inagaki, Kazuaki Nagashima, Shun-ichiro Asahara, Yukina Kawada, Yuki Shibutani, Hiroaki Etoh, Tomokazu Matsuda, Hiroshi Inoue, Alberto Bartolomé, Kyoko Teruyama, Tetsuya Hosooka, Yushi Hirota, Masato Kasuga, Michael J. Higgins, Susumu Seino, Michihiro Matsumoto, Naoko Hashimoto, Hiroyuki Inoue

مصطلحات موضوعية: Male, endocrine system diseases, Immunoblotting, Inheritance Patterns, Gene Expression, Locus (genetics), Biology, Epigenesis, Genetic, Genomic Imprinting, Insulin-Secreting Cells, Gene expression, Insulin Secretion, medicine, Animals, Insulin, Epigenetics, Allele, Gene, Cyclin-Dependent Kinase Inhibitor p57, Alleles, Genetics, Mice, Knockout, Multidisciplinary, KCNQ1OT1, urogenital system, Reverse Transcriptase Polymerase Chain Reaction, Pancreatic islets, Biological Sciences, Glucose Tolerance Test, Molecular biology, medicine.anatomical_structure, Glucose, KCNQ1 Potassium Channel, Mutation, Genomic imprinting

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3b5f2440f0d10794fc094e8edcd57ac
https://europepmc.org/articles/PMC4500236/

المؤلفون: Yoshito Fujimoto, Tetsuo Noda, Masato Kasuga, Yoshiaki Kido, Hitoshi Okamura, Tomokazu Matsuda, Yutaka Shigeyama, Pedro Luis Herrera, Akihiko Takeda, Naoko Hashimoto, Daisuke Tsuchihashi, Akihiko Nishizawa, Wataru Ogawa, Shun-ichiro Asahara, Tohru Uchida, Karen C. Arden

المصدر: Nature Genetics, Vol. 38, No 5 (2006) pp. 589-593

مصطلحات موضوعية: medicine.medical_specialty, medicine.medical_treatment, Islets of Langerhans/ enzymology/ pathology, FOXO1, Protein Serine-Threonine Kinases, Biology, Diabetes Mellitus, Experimental, 3-Phosphoinositide-Dependent Protein Kinases, Diabetes Mellitus, Experimental/enzymology/ genetics/pathology, Islets of Langerhans, Mice, Internal medicine, Insulin receptor substrate, Genetics, medicine, Animals, Glucose homeostasis, ddc:616, Mice, Knockout, geography, geography.geographical_feature_category, Insulin, Islet, Protein-Serine-Threonine Kinases/ genetics, medicine.anatomical_structure, Endocrinology, Signal transduction, Beta cell, Pancreas, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45c20c573f1d693c4793b918cac578a6
https://doi.org/10.1038/ng1774

المؤلفون: Yuko Fujiwara, Naoko Hashimoto, Toru Higashinakagawa, Hirokazu Fujimoto, Michihiko Ito, Takashi Takeuchi, Misae Yamanouchi, Toshiaki Noce

المصدر: Developmental Biology. 155:409-422

مصطلحات موضوعية: Male, Molecular Sequence Data, Restriction Mapping, Gene Expression, Biology, Nervous System, Mice, medicine, Animals, Amino Acid Sequence, Northern blot, Molecular Biology, In Situ Hybridization, Genetics, Zinc finger, Mice, Inbred ICR, Base Sequence, Neuroectoderm, Gonadal ridge, cDNA library, Embryogenesis, Neural crest, Zinc Fingers, DNA, Cell Biology, Blotting, Northern, Spermatozoa, Cell biology, DNA-Binding Proteins, Mice, Inbred C57BL, medicine.anatomical_structure, embryonic structures, Gene Deletion, Germ cell, Transcription Factors, Developmental Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6fb93c1c73e7a3128a8e2e9e04921b6
https://doi.org/10.1006/dbio.1993.1039

المؤلفون: Takanori Katsube, Manabu Takahisa, Atsushi Yamashita, Naoko Hashimoto, Yuka Sasaki, Shin Togashi, Ryu Ueda

المصدر: Genesgenetic systems. 76(2)

مصطلحات موضوعية: DNA, Complementary, Transcription, Genetic, Molecular Sequence Data, macromolecular substances, Exon, Genetics, Consensus sequence, Animals, Drosophila Proteins, Protein Isoforms, Cloning, Molecular, Molecular Biology, In Situ Hybridization, Genomic organization, Cloning, biology, Base Sequence, Models, Genetic, Reverse Transcriptase Polymerase Chain Reaction, Microfilament Proteins, Single-Strand Specific DNA and RNA Endonucleases, Intron, Chromosome, Chromosome Mapping, General Medicine, Exons, Introns, Blotting, Southern, biology.protein, Actin filament binding, Drosophila, Cortactin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0dd4852be2184c111f03abbd51a6173
https://pubmed.ncbi.nlm.nih.gov/11434460

المؤلفون: Megumi Fuchita, Yasuo Uchiyama, Yoshiaki Kido, Yutaka Shigeyama, Yuki Shibutani, Tetsutya Hosooka, Hiroshi Inoue, Tomokazu Matsuda, Ayumi Kanno, Tetsuo Noda, Masato Kasuga, Tomoko Mikami, Susumu Seino, Naoko Hashimoto, Shun-ichiro Asahara, Masato Koike, Michihiro Matsumoto, Maki Koyanagi

المصدر: PLoS ONE
PLoS ONE, Vol 6, Iss 8, p e23238 (2011)

مصطلحات موضوعية: Mitochondrial Diseases, medicine.medical_treatment, lcsh:Medicine, mTORC1, Mitochondrion, Biochemistry, Mice, RNA interference, Insulin-Secreting Cells, Insulin Secretion, Insulin, lcsh:Science, Gene knockdown, Multidisciplinary, TOR Serine-Threonine Kinases, Mitochondria, Insulin oscillation, Cell biology, Organ Specificity, Gene Knockdown Techniques, Research Article, congenital, hereditary, and neonatal diseases and abnormalities, medicine.medical_specialty, Mechanistic Target of Rapamycin Complex 1, Biology, Cell Line, Internal medicine, Tuberous Sclerosis Complex 2 Protein, Genetics, medicine, Animals, Insulinoma, Sirolimus, Tumor Suppressor Proteins, lcsh:R, Proteins, Human Genetics, medicine.disease, Insulin receptor, Glucose, Metabolism, Diabetes Mellitus and Deafness, Endocrinology, Mitochondrial biogenesis, Multiprotein Complexes, biology.protein, lcsh:Q, Gene expression, Gene Deletion

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef306198a30f7da4bde64729db5877ef
https://doi.org/10.1371/journal.pone.0023238