المؤلفون: Thorolfsdottir RB; deCODE genetics, Amgen, Reykjavik, Iceland., Jonsdottir AB; deCODE genetics, Amgen, Reykjavik, Iceland., Sveinbjornsson G; deCODE genetics, Amgen, Reykjavik, Iceland., Aegisdottir HM; deCODE genetics, Amgen, Reykjavik, Iceland., Oddsson A; deCODE genetics, Amgen, Reykjavik, Iceland., Stefansson OA; deCODE genetics, Amgen, Reykjavik, Iceland., Halldorsson GH; deCODE genetics, Amgen, Reykjavik, Iceland.; School of Engineering and Natural Sciences, University of Iceland, Reykjavik, Iceland., Saevarsdottir S; deCODE genetics, Amgen, Reykjavik, Iceland.; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland.; Department of Medicine, Landspitali, The National University Hospital of Iceland, Reykjavik, Iceland., Thorleifsson G; deCODE genetics, Amgen, Reykjavik, Iceland., Stefansdottir L; deCODE genetics, Amgen, Reykjavik, Iceland., Pedersen OB; Department of Clinical Immunology, Zealand University Hospital, Køge, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Sørensen E; Department of Clinical Immunology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark., Ghouse J; Department of Cardiology, The Heart Centre, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.; Laboratory for Molecular Cardiology, Department of Cardiology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark., Raja AA; Department of Cardiology, The Heart Centre, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark., Zheng C; Department of Cardiology, The Heart Centre, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark., Silajdzija E; Department of Cardiology, The Heart Centre, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark., Rand SA; Department of Cardiology, The Heart Centre, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.; Laboratory for Molecular Cardiology, Department of Cardiology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark., Erikstrup C; Department of Clinical Immunology, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark., Ullum H; Statens Serum Institut, Copenhagen, Denmark., Mikkelsen C; Department of Clinical Immunology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Science, University of Copenhagen, Copenhagen, Denmark., Banasik K; Department of Obstetrics and Gynaecology, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark.; Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Brunak S; Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Ivarsdottir EV; deCODE genetics, Amgen, Reykjavik, Iceland., Sigurdsson A; deCODE genetics, Amgen, Reykjavik, Iceland., Beyter D; deCODE genetics, Amgen, Reykjavik, Iceland., Sturluson A; deCODE genetics, Amgen, Reykjavik, Iceland., Einarsson H; deCODE genetics, Amgen, Reykjavik, Iceland.; School of Engineering and Natural Sciences, University of Iceland, Reykjavik, Iceland., Tragante V; deCODE genetics, Amgen, Reykjavik, Iceland., Helgason H; deCODE genetics, Amgen, Reykjavik, Iceland.; School of Engineering and Natural Sciences, University of Iceland, Reykjavik, Iceland., Lund SH; deCODE genetics, Amgen, Reykjavik, Iceland., Halldorsson BV; deCODE genetics, Amgen, Reykjavik, Iceland.; School of Technology, Reykjavik University, Reykjavik, Iceland., Sigurpalsdottir BD; deCODE genetics, Amgen, Reykjavik, Iceland.; School of Technology, Reykjavik University, Reykjavik, Iceland., Olafsson I; Department of Clinical Biochemistry, Landspitali, National University Hospital of Iceland, Reykjavik, Iceland., Arnar DO; deCODE genetics, Amgen, Reykjavik, Iceland.; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland.; Department of Medicine, Landspitali, The National University Hospital of Iceland, Reykjavik, Iceland., Thorgeirsson G; deCODE genetics, Amgen, Reykjavik, Iceland., Knowlton KU; Intermountain Medical Center, Intermountain Heart Institute, Salt Lake City, Utah.; School of Medicine, University of Utah, Salt Lake City., Nadauld LD; Precision Genomics, Intermountain Healthcare, Saint George, Utah.; School of Medicine, Stanford University, Stanford, California., Gretarsdottir S; deCODE genetics, Amgen, Reykjavik, Iceland., Helgadottir A; deCODE genetics, Amgen, Reykjavik, Iceland., Ostrowski SR; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Clinical Immunology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark., Gudbjartssson DF; deCODE genetics, Amgen, Reykjavik, Iceland.; School of Engineering and Natural Sciences, University of Iceland, Reykjavik, Iceland., Jonsdottir I; deCODE genetics, Amgen, Reykjavik, Iceland.; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland.; Department of Immunology, Landspitali, The National University Hospital of Iceland, Reykjavik, Iceland., Bundgaard H; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Cardiology, The Heart Centre, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark., Holm H; deCODE genetics, Amgen, Reykjavik, Iceland., Sulem P; deCODE genetics, Amgen, Reykjavik, Iceland., Stefansson K; deCODE genetics, Amgen, Reykjavik, Iceland.; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland.

مؤلفون مشاركون: Danish Blood Donor Study Genomic Consortium

المصدر: JAMA cardiology [JAMA Cardiol] 2024 Feb 01; Vol. 9 (2), pp. 165-172.

نوع المنشور: Journal Article; Comment

بيانات الدورية: Publisher: American Medical Association Country of Publication: United States NLM ID: 101676033 Publication Model: Print Cited Medium: Internet ISSN: 2380-6591 (Electronic) NLM ISO Abbreviation: JAMA Cardiol Subsets: MEDLINE

مواضيع طبية MeSH: Genome-Wide Association Study*, Humans ; Male ; Adolescent ; Female ; Genotype ; Phenotype ; Gene Frequency ; Finland

المؤلفون: Feng H; Program in Genetic Epidemiology and Statistical Genetics, Harvard T. H. Chan School of Public Health, Boston, Massachusetts.; Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, Massachusetts.; Department of Biostatistics, Harvard T. H. Chan School of Public Health, Boston, Massachusetts., Gusev A; Dana-Farber Cancer Institute, Boston, Massachusetts., Pasaniuc B; UCLA Path & Lab Med, Los Angeles, California., Wu L; Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii., Long J; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee., Abu-Full Z; Clalit National Cancer Control Center, Carmel Medical Center and Technion Faculty of Medicine, Haifa, Israel., Aittomäki K; Department of Clinical Genetics, Helsinki University Hospital, University of Helsinki, Helsinki, Finland., Andrulis IL; Fred A, Litwin Center for Cancer Genetics, Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada., Anton-Culver H; Department of Epidemiology, Genetic Epidemiology Research Institute, University of California Irvine, Irvine, California., Antoniou AC; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Arason A; Department of Pathology, Landspitali University Hospital, Reykjavik, Iceland.; BMC (Biomedical Centre), Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Arndt V; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany., Aronson KJ; Department of Public Health Sciences, and Cancer Research Institute, Queen's University, Kingston, Ontario, Canada., Arun BK; Department of Breast Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas., Asseryanis E; Department of OB/GYN and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria., Auer PL; Cancer Prevention Program, Fred Hutchinson Cancer Research Center, Seattle, Washington.; Zilber School of Public Health, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin., Azzollini J; Unit of Medical Genetics, Department of Medical Oncology and Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy., Balmaña J; High Risk and Cancer Prevention Group, Vall d'Hebron Institute of Oncology, Barcelona, Spain., Barkardottir RB; Department of Pathology, Landspitali University Hospital, Reykjavik, Iceland.; BMC (Biomedical Centre), Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Barnes DR; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Barrowdale D; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Beckmann MW; Department of Gynecology and Obstetrics, Comprehensive Cancer Center ER-EMN, University Hospital Erlangen, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany., Behrens S; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Benitez J; Centro de Investigaci-n en Red de Enfermedades Raras (CIBERER), Madrid, Spain.; Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain., Bermisheva M; Institute of Biochemistry and Genetics, Ufa Federal Research Centre of the Russian Academy of Sciences, Ufa, Russia., Białkowska K; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland., Blanco A; Centro de Investigaci-n en Red de Enfermedades Raras (CIBERER), Madrid, Spain.; Fundaci-n Pœblica Galega Medicina Xen-mica, Santiago De Compostela, Spain.; Instituto de Investigacion Sanitaria de Santiago de Compostela, Santiago de Compostela, Spain., Blomqvist C; Department of Oncology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland.; Department of Oncology, University Hospital, Karolinska Institute, Stockholm, Sweden., Boeckx B; VIB Center for Cancer Biology, VIB, Leuven, Belgium.; Laboratory for Translational Genetics, Department of Human Genetics, University of Leuven, Leuven, Belgium., Bogdanova NV; Department of Radiation Oncology, Hannover Medical School, Hannover, Germany.; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany.; NN Alexandrov Research Institute of Oncology and Medical Radiology, Minsk, Belarus., Bojesen SE; Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Bolla MK; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Bonanni B; Division of Cancer Prevention and Genetics, IEO, European Institute of Oncology IRCCS, Milan, Italy., Borg A; Department of Oncology, Lund University and Skåne University Hospital, Lund, Sweden., Brauch H; Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany.; iFIT-Cluster of Excellence, University of Tuebingen, Tuebingen, Germany.; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany., Brenner H; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.; Division of Preventive Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Heidelberg, Germany., Briceno I; Institute of Human Genetics, Pontificia Universidad Javeriana, Bogota, Colombia.; Medical Faculty, Universidad de La Sabana, Bogota, Colombia., Broeks A; Division of Molecular Pathology, The Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands., Brüning T; Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr University Bochum (IPA), Bochum, Germany., Burwinkel B; Molecular Epidemiology Group, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Molecular Biology of Breast Cancer, University Womens Clinic Heidelberg, University of Heidelberg, Heidelberg, Germany., Cai Q; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee., Caldés T; Medical Oncology Department, Hospital Cl'nico San Carlos, Instituto de Investigaci-n Sanitaria San Carlos (IdISSC), Centro Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain., Caligo MA; Section of Molecular Genetics, Dept, of Laboratory Medicine, University Hospital of Pisa, Pisa, Italy., Campbell I; Research Department, Peter MacCallum Cancer Center, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, Victoria, Australia., Canisius S; Division of Molecular Pathology, The Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.; Division of Molecular Carcinogenesis, The Netherlands Cancer Institute-Antoni van Leeuwenhoek hospital, Amsterdam, The Netherlands., Campa D; Genomic Epidemiology Group, German Cancer Research Center (DKFZ), Heidelberg, Germany., Carter BD; Behavioral and Epidemiology Research Group, American Cancer Society, Atlanta, Georgia., Carter J; Department of Gynaecological Oncology, Chris OÕBrien Lifehouse and The University of Sydney, Camperdown, New South Wales, Australia., Castelao JE; Oncology and Genetics Unit, Instituto de Investigacion Sanitaria Galicia Sur (IISGS), Xerencia de Xestion Integrada de Vigo-SERGAS, Vigo, Spain., Chang-Claude J; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Cancer Epidemiology Group, University Cancer Center Hamburg (UCCH), University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Chanock SJ; Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, Maryland., Christiansen H; Department of Radiation Oncology, Hannover Medical School, Hannover, Germany., Chung WK; Departments of Pediatrics and Medicine, Columbia University, New York, New York., Claes KBM; Centre for Medical Genetics, Ghent University, Gent, Belgium., Clarke CL; Westmead Institute for Medical Research, University of Sydney, Sydney, New South Wales, Australia., Couch FJ; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota., Cox A; Department of Oncology and Metabolism, Sheffield Institute for Nucleic Acids (SInFoNiA), University of Sheffield, Sheffield, UK., Cross SS; Academic Unit of Pathology, Department of Neuroscience, University of Sheffield, Sheffield, UK., Cybulski C; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland., Czene K; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Daly MB; Department of Clinical Genetics, Fox Chase Cancer Center, Philadelphia, Pennsylvania., de la Hoya M; Medical Oncology Department, Hospital Cl'nico San Carlos, Instituto de Investigaci-n Sanitaria San Carlos (IdISSC), Centro Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain., De Leeneer K; Centre for Medical Genetics, Ghent University, Gent, Belgium., Dennis J; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Devilee P; Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands.; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands., Diez O; Hereditary Cancer Genetics Group, Area of Clinical and Molecular Genetics, Vall dHebron Institute of Oncology (VHIO), University Hospital Vall d'Hebron, Barcelona, Spain.; Clinical and Molecular Genetics Area, University Hospital Vall dHebron, Barcelona, Spain., Domchek SM; Department of Medicine, Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania., Dörk T; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany., Dos-Santos-Silva I; Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK., Dunning AM; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Dwek M; Department of Biomedical Sciences, Faculty of Science and Technology, University of Westminster, London, UK., Eccles DM; Cancer Sciences Academic Unit, Faculty of Medicine, University of Southampton, Southampton, UK., Ejlertsen B; Department of Oncology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., Ellberg C; Department of Cancer Epidemiology, Clinical Sciences, Lund University, Lund, Sweden., Engel C; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany.; LIFE - Leipzig Research Centre for Civilization Diseases, University of Leipzig, Leipzig, Germany., Eriksson M; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Fasching PA; Department of Gynecology and Obstetrics, Comprehensive Cancer Center ER-EMN, University Hospital Erlangen, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany.; David Geffen School of Medicine, Department of Medicine Division of Hematology and Oncology, University of California at Los Angeles, Los Angeles, California., Fletcher O; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK., Flyger H; Department of Breast Surgery, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark., Fostira F; Molecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research 'Demokritosဩ, Athens, Greece., Friedman E; The Susanne Levy Gertner Oncogenetics Unit, Chaim Sheba Medical Center, Ramat Gan, Israel.; Sackler Faculty of Medicine, Tel Aviv University, Ramat Aviv, Israel., Fritschi L; School of Public Health, Curtin University, Perth, Western Australia, Australia., Frost D; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Gabrielson M; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Ganz PA; Schools of Medicine and Public Health, Division of Cancer Prevention & Control Research, Jonsson Comprehensive Cancer Centre, UCLA, Los Angeles, California., Gapstur SM; Behavioral and Epidemiology Research Group, American Cancer Society, Atlanta, Georgia., Garber J; Cancer Risk and Prevention Clinic, Dana-Farber Cancer Institute, Boston, Massachusetts., García-Closas M; Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.; Division of Genetics and Epidemiology, Institute of Cancer Research, London, UK.; Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Victoria, Australia., García-Sáenz JA; Medical Oncology Department, Hospital Cl'nico San Carlos, Instituto de Investigaci-n Sanitaria San Carlos (IdISSC), Centro Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain., Gaudet MM; Behavioral and Epidemiology Research Group, American Cancer Society, Atlanta, Georgia., Giles GG; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia.; Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia., Glendon G; Fred A, Litwin Center for Cancer Genetics, Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada., Godwin AK; Department of Pathology and Laboratory Medicine, Kansas University Medical Center, Kansas City, Kanas., Goldberg MS; Department of Medicine, McGill University, Montreal, Quebec, Canada.; Division of Clinical Epidemiology, Royal Victoria Hospital, McGill University, Montreal, Quebec, Canada., Goldgar DE; Department of Dermatology, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, Utah., González-Neira A; Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain., Greene MH; Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland., Gronwald J; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland., Guénel P; Cancer & Environment Group, Center for Research in Epidemiology and Population Health (CESP), INSERM, University Paris-Sud, University Paris-Saclay, Villejuif, France., Haiman CA; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California., Hall P; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.; Department of Oncology, Sšdersjukhuset, Stockholm, Sweden., Hamann U; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany., Hake C; City of Hope Clinical Cancer Genetics Community Research Network, Duarte, California., He W; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Heyworth J; School of Population and Global Health, The University of Western Australia, Perth, Western Australia, Australia., Hogervorst FBL; Family Cancer Clinic, The Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands., Hollestelle A; Department of Medical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute, Rotterdam, The Netherlands., Hooning MJ; Department of Medical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute, Rotterdam, The Netherlands., Hoover RN; Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, Maryland., Hopper JL; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia., Huang G; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany., Hulick PJ; Center for Medical Genetics, NorthShore University HealthSystem, Evanston, Illinois.; The University of Chicago Pritzker School of Medicine, Chicago, Illinois., Humphreys K; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Imyanitov EN; NN Petrov Institute of Oncology, St. Petersburg, Russia., Isaacs C; Lombardi Comprehensive Cancer Center, Georgetown University, Washington, District of Columbia., Jakimovska M; Research Centre for Genetic Engineering and Biotechnology 'Georgi D, Efremov', Macedonian Academy of Sciences and Arts, Skopje Republic of North Macedonia, North Macedonia., Jakubowska A; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.; Independent Laboratory of Molecular Biology and Genetic Diagnostics, Pomeranian Medical University, Szczecin, Poland., James P; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, Victoria, Australia.; Parkville Familial Cancer Centre, Peter MacCallum Cancer Center, Melbourne, Victoria, Australia., Janavicius R; State Research Institute Innovative Medicine Center, Vilnius, Lithuania., Jankowitz RC; Department of Medicine, Division of Hematology/Oncology, UPMC Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania., John EM; Department of Medicine, Division of Oncology, Stanford Cancer Institute, Stanford University School of Medicine, Stanford, California., Johnson N; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK., Joseph V; Clinical Genetics Research Lab, Department of Cancer Biology and Genetics, Memorial Sloan-Kettering Cancer Center, New York, New York., Jung A; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Karlan BY; David Geffen School of Medicine, Department of Obstetrics and Gynecology, University of California, Los Angeles, California., Khusnutdinova E; Institute of Biochemistry and Genetics, Ufa Federal Research Centre of the Russian Academy of Sciences, Ufa, Russia.; Department of Genetics and Fundamental Medicine, Bashkir State Medical University, Ufa, Russia., Kiiski JI; Department of Obstetrics and Gynecology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland., Konstantopoulou I; Molecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research 'Demokritosဩ, Athens, Greece., Kristensen VN; Department of Cancer Genetics, Institute for Cancer Research, Oslo University Hospital-Radiumhospitalet, Oslo, Norway.; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway., Laitman Y; The Susanne Levy Gertner Oncogenetics Unit, Chaim Sheba Medical Center, Ramat Gan, Israel., Lambrechts D; VIB Center for Cancer Biology, VIB, Leuven, Belgium.; Laboratory for Translational Genetics, Department of Human Genetics, University of Leuven, Leuven, Belgium., Lazaro C; Molecular Diagnostic Unit, Hereditary Cancer Program, ICO-IDIBELL (Bellvitge Biomedical Research Institute, Catalan Institute of Oncology), CIBERONC, Barcelona, Spain., Leroux D; Departement de Ge netique, CHU de Grenoble, Grenoble, France., Leslie G; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Lester J; David Geffen School of Medicine, Department of Obstetrics and Gynecology, University of California, Los Angeles, California., Lesueur F; Institut Curie, Paris, France.; Mines ParisTech, Fontainebleau, France.; Genetic Epidemiology of Cancer Team, Inserm U900, Paris, France., Lindor N; Department of Health Sciences Research, Mayo Clinic, Scottsdale, Arizona., Lindström S; Department of Epidemiology, University of Washington School of Public Health, Seattle, Washington.; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington., Lo WY; Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany.; iFIT-Cluster of Excellence, University of Tuebingen, Tuebingen, Germany., Loud JT; Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland., Lubiński J; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland., Makalic E; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia., Mannermaa A; Translational Cancer Research Area, University of Eastern Finland, Kuopio, Finland.; Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, Kuopio, Finland.; Imaging Center, Department of Clinical Pathology, Kuopio University Hospital, Kuopio, Finland., Manoochehri M; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany., Manoukian S; Unit of Medical Genetics, Department of Medical Oncology and Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy., Margolin S; Department of Oncology, Sšdersjukhuset, Stockholm, Sweden.; Department of Clinical Science and Education, Sšdersjukhuset, Karolinska Institutet, Stockholm, Sweden., Martens JWM; Department of Medical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute, Rotterdam, The Netherlands., Martinez ME; Moores Cancer Center, University of California San Diego, La Jolla, California.; Department of Family Medicine and Public Health, University of California San Diego, La Jolla, California., Matricardi L; Immunology and Molecular Oncology Unit, Veneto Institute of Oncology ÊIOV-IRCCS, Padua, Italy., Maurer T; Cancer Epidemiology Group, University Cancer Center Hamburg (UCCH), University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Mavroudis D; Department of Medical Oncology, University Hospital of Heraklion, Heraklion, Greece., McGuffog L; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Meindl A; Department of Gynecology and Obstetrics, Ludwig Maximilian University of Munich, Munich, Germany., Menon U; MRC Clinical Trials Unit at UCL, Institute of Clinical Trials & Methodology, University College London, London, UK., Michailidou K; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Department of Electron Microscopy/Molecular Pathology and The Cyprus School of Molecular Medicine, The Cyprus Institute of Neurology & Genetics, Nicosia, Cyprus., Kapoor PM; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Faculty of Medicine, University of Heidelberg, Heidelberg, Germany., Miller A; NRG Oncology, Statistics and Data Management Center, Roswell Park Cancer Institute, Buffalo, New York., Montagna M; Immunology and Molecular Oncology Unit, Veneto Institute of Oncology ÊIOV-IRCCS, Padua, Italy., Moreno F; Medical Oncology Department, Hospital Cl'nico San Carlos, Instituto de Investigaci-n Sanitaria San Carlos (IdISSC), Centro Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain., Moserle L; Immunology and Molecular Oncology Unit, Veneto Institute of Oncology ÊIOV-IRCCS, Padua, Italy., Mulligan AM; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.; Laboratory Medicine Program, University Health Network, Toronto, Ontario, Canada., Muranen TA; Department of Obstetrics and Gynecology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland., Nathanson KL; Department of Medicine, Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania., Neuhausen SL; Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, California., Nevanlinna H; Department of Obstetrics and Gynecology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland., Nevelsteen I; Leuven Multidisciplinary Breast Center, Department of Oncology, Leuven Cancer Institute, University Hospitals Leuven, Leuven, Belgium., Nielsen FC; Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., Nikitina-Zake L; Latvian Biomedical Research and Study Centre, Riga, Latvia., Offit K; Clinical Genetics Research Lab, Department of Cancer Biology and Genetics, Memorial Sloan-Kettering Cancer Center, New York, New York.; Clinical Genetics Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York., Olah E; Department of Molecular Genetics, National Institute of Oncology, Budapest, Hungary., Olopade OI; Center for Clinical Cancer Genetics, The University of Chicago, Chicago, Illinois., Olsson H; Department of Cancer Epidemiology, Clinical Sciences, Lund University, Lund, Sweden., Osorio A; Centro de Investigaci-n en Red de Enfermedades Raras (CIBERER), Madrid, Spain.; Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain., Papp J; Department of Molecular Genetics, National Institute of Oncology, Budapest, Hungary., Park-Simon TW; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany., Parsons MT; Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Pedersen IS; Section of Molecular Diagnostics, Clinical Biochemistry, Aalborg University Hospital, Aalborg, Denmark., Peixoto A; Department of Genetics, Portuguese Oncology Institute, Porto, Portugal., Peterlongo P; Genome Diagnostics Program, IFOM-The FIRC (Italian Foundation for Cancer Research) Institute of Molecular Oncology, Milan, Italy., Peto J; Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK., Pharoah PDP; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Phillips KA; Research Department, Peter MacCallum Cancer Center, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, Victoria, Australia.; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia.; Department of Medicine Oncology, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Plaseska-Karanfilska D; Research Centre for Genetic Engineering and Biotechnology 'Georgi D, Efremov', Macedonian Academy of Sciences and Arts, Skopje Republic of North Macedonia, North Macedonia., Poppe B; Centre for Medical Genetics, Ghent University, Gent, Belgium., Pradhan N; Clinical Genetics Research Lab, Department of Cancer Biology and Genetics, Memorial Sloan-Kettering Cancer Center, New York, New York., Prajzendanc K; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland., Presneau N; Department of Biomedical Sciences, Faculty of Science and Technology, University of Westminster, London, UK., Punie K; Leuven Multidisciplinary Breast Center, Department of Oncology, Leuven Cancer Institute, University Hospitals Leuven, Leuven, Belgium., Pylkäs K; Laboratory of Cancer Genetics and Tumor Biology, Cancer and Translational Medicine Research Unit, Biocenter Oulu, University of Oulu, Oulu, Finland.; Laboratory of Cancer Genetics and Tumor Biology, Northern Finland Laboratory Centre Oulu, Oulu, Finland., Radice P; Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Research, Fondazione IRCCS Istituto Nazionale dei Tumori (INT), Milan, Italy., Rantala J; 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Division of Molecular Medicine, Pathology North, John Hunter Hospital, Newcastle, New South Wales, Australia.; Discipline of Medical Genetics, School of Biomedical Sciences and Pharmacy, Faculty of Health, University of Newcastle, Callaghan, New South Wales, Australia.; Hunter Medical Research Institute, John Hunter Hospital, Newcastle, New South Wales, Australia., Sharma P; Department of Internal Medicine, Division of Medical Oncology, University of Kansas Medical Center, Westwood, Kanas., Shu XO; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee., Simard J; Genomics Center, Centre Hospitalier Universitaire de Quebec-Universite Laval, Research Center, Quebec City, Qubec, Canada., Singer CF; Department of OB/GYN and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria., Skytte AB; Department of Clinical Genetics, Aarhus University Hospital, Aarhus N, Denmark., Soucy P; Genomics Center, Centre Hospitalier Universitaire de Quebec-Universite Laval, Research Center, Quebec City, Qubec, Canada., Southey MC; Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, Victoria, Australia.; Department of Clinical Pathology, The University of Melbourne, Melbourne, Victoria, Australia., Spinelli JJ; Population Oncology, BC Cancer, Vancouver, British of Columbia, Canada.; School of Population and Public Health, University of British Columbia, Vancouver, British of Columbia, Canada., Spurdle AB; Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Stone J; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia.; The Curtin UWA Centre for Genetic Origins of Health and Disease, Curtin University and University of Western Australia, Perth, Western Australia, Australia., Swerdlow AJ; Division of Genetics and Epidemiology, Institute of Cancer Research, London, UK.; Division of Breast Cancer Research, The Institute of Cancer Research, London, UK., Tapper WJ; Faculty of Medicine, University of Southampton, Southampton, UK., Taylor JA; Epidemiology Branch, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, North Carolina.; Epigenetic and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, North Carolina., Teixeira MR; Department of Genetics, Portuguese Oncology Institute, Porto, Portugal.; Biomedical Sciences Institute (ICBAS), University of Porto, Porto, Portugal., Terry MB; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York., Teulé A; Genetic Counseling Unit, Hereditary Cancer Program, IDIBELL (Bellvitge Biomedical Research Institute), Catalan Institute of Oncology, CIBERONC, Barcelona, Spain., Thomassen M; Department of Clinical Genetics, Odense University Hospital, Odence C, Denmark., Thöne K; Cancer Epidemiology Group, University Cancer Center Hamburg (UCCH), University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Thull DL; Department of Medicine, Magee-Womens Hospital, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania., Tischkowitz M; Program in Cancer Genetics, Departments of Human Genetics and Oncology, McGill University, Montreal, Quebec, Canada.; Department of Medical Genetics, University of Cambridge, Cambridge, UK., Toland AE; Department of Cancer Biology and Genetics, The Ohio State University, Columbus, Ohio., Tollenaar RAEM; Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands., Torres D; Institute of Human Genetics, Pontificia Universidad Javeriana, Bogota, Colombia.; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany., Truong T; Cancer & Environment Group, Center for Research in Epidemiology and Population Health (CESP), INSERM, University Paris-Sud, University Paris-Saclay, Villejuif, France., Tung N; 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Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Wappenschmidt B; Center for Hereditary Breast and Ovarian Cancer, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany., Weinberg CR; Biostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, North Carolina., Weitzel JN; Clinical Cancer Genomics, City of Hope, Duarte, California., Wendt C; Department of Clinical Science and Education, Sšdersjukhuset, Karolinska Institutet, Stockholm, Sweden., Winqvist R; Laboratory of Cancer Genetics and Tumor Biology, Cancer and Translational Medicine Research Unit, Biocenter Oulu, University of Oulu, Oulu, Finland.; Laboratory of Cancer Genetics and Tumor Biology, Northern Finland Laboratory Centre Oulu, Oulu, Finland., Yang XR; 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مؤلفون مشاركون: GEMO Study Collaborators; Department of Tumour Biology, INSERM U830, Paris, France.; Institut Curie, Paris, France.; Mines ParisTech, Fontainebleau, France., EMBRACE Collaborators; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., GC-HBOC study Collaborators; Center for Hereditary Breast and Ovarian Cancer, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany., ABCTB Investigators; Australian Breast Cancer Tissue Bank, Westmead Institute for Medical Research, University of Sydney, Sydney, New South Wales, Australia., HEBON Investigators; The Hereditary Breast and Ovarian Cancer Research Group Netherlands (HEBON), Coordinating Center, The Netherlands Cancer Institute, Amsterdam, The Netherlands., BCFR Investigators; Department of Medicine, Division of Oncology, Stanford Cancer Institute, Stanford University School of Medicine, Stanford, California., OCGN Investigators; Ontario Cancer Genetics Network, Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada.

المصدر: Genetic epidemiology [Genet Epidemiol] 2020 Jul; Vol. 44 (5), pp. 442-468. Date of Electronic Publication: 2020 Mar 01.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8411723 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-2272 (Electronic) Linking ISSN: 07410395 NLM ISO Abbreviation: Genet Epidemiol Subsets: MEDLINE

مواضيع طبية MeSH: Genome-Wide Association Study*, Breast Neoplasms/*genetics , Receptors, Estrogen/*metabolism, Breast Neoplasms/metabolism ; Estrogens/metabolism ; Female ; Genetic Predisposition to Disease ; Genomics ; Humans ; Risk Assessment ; Transcriptome ; Vesicular Transport Proteins/genetics

المؤلفون: Fachal L; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Aschard H; Centre de Bioinformatique Biostatistique et Biologie Intégrative (C3BI), Institut Pasteur, Paris, France.; Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, MA, USA.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA., Beesley J; Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Barnes DR; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Allen J; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Kar S; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Pooley KA; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Dennis J; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Michailidou K; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Department of Electron Microscopy/Molecular Pathology and The Cyprus School of Molecular Medicine, The Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus., Turman C; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA., Soucy P; Genomics Center, Centre Hospitalier Universitaire de Québec, Université Laval Research Center, Québec City, Québec, Canada., Lemaçon A; Genomics Center, Centre Hospitalier Universitaire de Québec, Université Laval Research Center, Québec City, Québec, Canada., Lush M; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Tyrer JP; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Ghoussaini M; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Moradi Marjaneh M; Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.; UK Dementia Research Institute, Imperial College London, London, UK., Jiang X; Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, MA, USA., Agata S; Immunology and Molecular Oncology Unit, Veneto Institute of Oncology (IOV), IRCCS, Padua, Italy., Aittomäki K; Department of Clinical Genetics, Helsinki University Hospital, University of Helsinki, Helsinki, Finland., Alonso MR; Human Genotyping-CEGEN Unit, Human Cancer Genetic Program, Spanish National Cancer Research Centre, Madrid, Spain., Andrulis IL; Fred A. Litwin Center for Cancer Genetics, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada., Anton-Culver H; Department of Epidemiology, Genetic Epidemiology Research Institute, University of California, Irvine, Irvine, CA, USA., Antonenkova NN; N.N. Alexandrov Research Institute of Oncology and Medical Radiology, Minsk, Belarus., Arason A; Department of Pathology, Landspitali University Hospital, Reykjavik, Iceland.; BMC (Biomedical Centre), Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Arndt V; Division of Clinical Epidemiology and Aging Research (C070), German Cancer Research Center (DKFZ), Heidelberg, Germany., Aronson KJ; Department of Public Health Sciences and Cancer Research Institute, Queen's University, Kingston, Ontario, Canada., Arun BK; Department of Breast Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Auber B; Institute of Human Genetics, Hannover Medical School, Hannover, Germany., Auer PL; Cancer Prevention Program, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; Zilber School of Public Health, University of Wisconsin-Milwaukee, Milwaukee, WI, USA., Azzollini J; Unit of Medical Genetics, Department of Medical Oncology and Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy., Balmaña J; High Risk and Cancer Prevention Group, Vall Hebron Institute of Oncology, Barcelona, Spain.; Department of Medical Oncology, Vall Hebron University Hospital, Barcelona, Spain., Barkardottir RB; Department of Pathology, Landspitali University Hospital, Reykjavik, Iceland.; BMC (Biomedical Centre), Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Barrowdale D; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Beeghly-Fadiel A; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA., Benitez J; Centro de Investigación en Biomédica en Red de Enfermedades Raras (CIBERER), Madrid, Spain.; Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain., Bermisheva M; Institute of Biochemistry and Genetics, Ufa Federal Research Centre of the Russian Academy of Sciences, Ufa, Russia., Białkowska K; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland., Blanco AM; Cancer Genetics and Prevention Program, University of California, San Francisco, San Francisco, CA, USA., Blomqvist C; Department of Oncology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland.; Department of Oncology, Örebro University Hospital, Örebro, Sweden., Blot W; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA.; International Epidemiology Institute, Rockville, MD, USA., Bogdanova NV; N.N. Alexandrov Research Institute of Oncology and Medical Radiology, Minsk, Belarus.; Department of Radiation Oncology, Hannover Medical School, Hannover, Germany.; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany., Bojesen SE; Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Bolla MK; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Bonanni B; Division of Cancer Prevention and Genetics, European Institute of Oncology (IEO), IRCCS, Milan, Italy., Borg A; Department of Oncology, Lund University and Skåne University Hospital, Lund, Sweden., Bosse K; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany., Brauch H; Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany.; iFIT Cluster of Excellence, University of Tuebingen, Tuebingen, Germany.; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany., Brenner H; Division of Clinical Epidemiology and Aging Research (C070), German Cancer Research Center (DKFZ), Heidelberg, Germany.; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.; Division of Preventive Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Heidelberg, Germany., Briceno I; Institute of Human Genetics, Pontificia Universidad Javeriana, Bogota, Colombia.; Medical Faculty, Universidad de La Sabana, Bogota, Colombia., Brock IW; Sheffield Institute for Nucleic Acids (SInFoNiA), Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK., Brooks-Wilson A; Genome Sciences Centre, BC Cancer Agency, Vancouver, British Columbia, Canada.; Department of Biomedical Physiology and Kinesiology, Simon Fraser University, Burnaby, British Columbia, Canada., Brüning T; Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr University Bochum (IPA), Bochum, Germany., Burwinkel B; Molecular Epidemiology Group (C080), German Cancer Research Center (DKFZ), Heidelberg, Germany.; Molecular Biology of Breast Cancer, University Womens Clinic Heidelberg, University of Heidelberg, Heidelberg, Germany., Buys SS; Department of Medicine, Huntsman Cancer Institute, Salt Lake City, UT, USA., Cai Q; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA., Caldés T; Molecular Oncology Laboratory, CIBERONC, Hospital Clinico San Carlos, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Madrid, Spain., Caligo MA; SOD Genetica Molecolare, University Hospital, Pisa, Italy., Camp NJ; Department of Internal Medicine, Huntsman Cancer Institute, Salt Lake City, UT, USA., Campbell I; Research Department, Peter MacCallum Cancer Center, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, Victoria, Australia., Canzian F; Genomic Epidemiology Group, German Cancer Research Center (DKFZ), Heidelberg, Germany., Carroll JS; Cancer Research UK Cambridge Institute, Li Ka Shing Centre, University of Cambridge, Cambridge, UK., Carter BD; Behavioral and Epidemiology Research Group, American Cancer Society, Atlanta, GA, USA., Castelao JE; Oncology and Genetics Unit, Instituto de Investigacion Sanitaria Galicia Sur (IISGS), Xerencia de Xestion Integrada de Vigo-SERGAS, Vigo, Spain., Chiquette J; Axe Oncologie, Centre de Recherche, Centre Hospitalier Universitaire de Québec, Université Laval, Québec, Québec, Canada., Christiansen H; Department of Radiation Oncology, Hannover Medical School, Hannover, Germany., Chung WK; Departments of Pediatrics and Medicine, Columbia University, New York, NY, USA., Claes KBM; Centre for Medical Genetics, Ghent University, Ghent, Belgium., Clarke CL; Westmead Institute for Medical Research, University of Sydney, Sydney, New South Wales, Australia., Collée JM; Department of Clinical Genetics, Erasmus University Medical Center, Rotterdam, the Netherlands., Cornelissen S; Division of Molecular Pathology, Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands., Couch FJ; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA., Cox A; Sheffield Institute for Nucleic Acids (SInFoNiA), Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK., Cross SS; Academic Unit of Pathology, Department of Neuroscience, University of Sheffield, Sheffield, UK., Cybulski C; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland., Czene K; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Daly MB; Department of Clinical Genetics, Fox Chase Cancer Center, Philadelphia, PA, USA., de la Hoya M; Molecular Oncology Laboratory, CIBERONC, Hospital Clinico San Carlos, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Madrid, Spain., Devilee P; Department of Pathology, Leiden University Medical Center, Leiden, the Netherlands.; Department of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands., Diez O; Oncogenetics Group, Vall d'Hebron Institute of Oncology, Barcelona, Spain.; Clinical and Molecular Genetics Area, Vall Hebron University Hospital, Barcelona, Spain., Ding YC; Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, CA, USA., Dite GS; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia., Domchek SM; Basser Center for BRCA, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA., Dörk T; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany., Dos-Santos-Silva I; Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK., Droit A; Genomics Center, Centre Hospitalier Universitaire de Québec, Université Laval Research Center, Québec City, Québec, Canada.; Département de Médecine Moléculaire, Faculté de Médecine, Centre de Recherche, Centre Hospitalier Universitaire de Québec, Laval University, Québec City, Québec, Canada., Dubois S; Genomics Center, Centre Hospitalier Universitaire de Québec, Université Laval Research Center, Québec City, Québec, Canada., Dumont M; Genomics Center, Centre Hospitalier Universitaire de Québec, Université Laval Research Center, Québec City, Québec, Canada., Duran M; Cáncer Hereditario, Instituto de Biología y Genética Molecular (IBGM), Universidad de Valladolid Centro Superior de Investigaciones Científicas (UVA-CSIC), Valladolid, Spain., Durcan L; Southampton Clinical Trials Unit, Faculty of Medicine, University of Southampton, Southampton, UK.; Cancer Sciences Academic Unit, Faculty of Medicine, University of Southampton, Southampton, UK., Dwek M; School of Life Sciences, University of Westminster, London, UK., Eccles DM; Faculty of Medicine, University of Southampton, Southampton, UK., Engel C; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany., Eriksson M; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Evans DG; Division of Evolution and Genomic Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.; North West Genomics Laboratory Hub, Manchester Centre for Genomic Medicine, St Mary's Hospital, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK., Fasching PA; David Geffen School of Medicine, Department of Medicine, Division of Hematology and Oncology, University of California, Los Angeles, Los Angeles, CA, USA.; Department of Gynecology and Obstetrics, Comprehensive Cancer Center ER-EMN, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany., Fletcher O; Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK., Floris G; Leuven Multidisciplinary Breast Center, Department of Oncology, Leuven Cancer Institute, University Hospitals Leuven, Leuven, Belgium., Flyger H; Department of Breast Surgery, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark., Foretova L; Department of Cancer Epidemiology and Genetics, Masaryk Memorial Cancer Institute, Brno, Czech Republic., Foulkes WD; Program in Cancer Genetics, Departments of Human Genetics and Oncology, McGill University, Montréal, Québec, Canada., Friedman E; The Suzanne Levy-Gertner Oncogenetics Unit, Chaim Sheba Medical Center, Ramat Gan, Israel.; Sackler Faculty of Medicine, Tel Aviv University, Ramat Aviv, Israel., Fritschi L; School of Public Health, Curtin University, Perth, Western Australia, Australia., Frost D; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Gabrielson M; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Gago-Dominguez M; Genomic Medicine Group, Galician Foundation of Genomic Medicine, Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Complejo Hospitalario Universitario de Santiago, SERGAS, Santiago de Compostela, Spain.; Moores Cancer Center, University of California, San Diego, La Jolla, CA, USA., Gambino G; SOD Genetica Molecolare, University Hospital, Pisa, Italy., Ganz PA; Schools of Medicine and Public Health, Division of Cancer Prevention and Control Research, Jonsson Comprehensive Cancer Centre, University of California, Los Angeles, Los Angeles, CA, USA., Gapstur SM; Behavioral and Epidemiology Research Group, American Cancer Society, Atlanta, GA, USA., Garber J; Cancer Risk and Prevention Clinic, Dana-Farber Cancer Institute, Boston, MA, USA., García-Sáenz JA; Medical Oncology Department, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria San Carlos (IdISSC), Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain., Gaudet MM; Behavioral and Epidemiology Research Group, American Cancer Society, Atlanta, GA, USA., Georgoulias V; Department of Medical Oncology, University Hospital of Heraklion, Heraklion, Greece., Giles GG; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia.; Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Victoria, Australia.; Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Melbourne, Victoria, Australia., Glendon G; Fred A. Litwin Center for Cancer Genetics, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada., Godwin AK; Department of Pathology and Laboratory Medicine, Kansas University Medical Center, Kansas City, KS, USA., Goldberg MS; Department of Medicine, McGill University, Montréal, Québec, Canada.; Division of Clinical Epidemiology, Royal Victoria Hospital, McGill University, Montréal, Québec, Canada., Goldgar DE; Department of Dermatology, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, UT, USA., González-Neira A; Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain., Tibiletti MG; U.O. Anatomia Patologica Ospedale di Circolo, ASST Settelaghi, Varese, Italy., Greene MH; Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Grip M; Department of Surgery, Oulu University Hospital, University of Oulu, Oulu, Finland., Gronwald J; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland., Grundy A; Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CHUM), Université de Montréal, Montréal, Québec, Canada., Guénel P; Cancer and Environment Group, Center for Research in Epidemiology and Population Health (CESP), INSERM, University Paris-Sud, University Paris-Saclay, Paris, France., Hahnen E; Center for Hereditary Breast and Ovarian Cancer, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Center for Integrated Oncology (CIO), Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany., Haiman CA; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Håkansson N; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Hall P; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.; Department of Oncology, Södersjukhuset, Stockholm, Sweden., Hamann U; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany., Harrington PA; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Hartikainen JM; Translational Cancer Research Area, University of Eastern Finland, Kuopio, Finland.; Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, Kuopio, Finland.; Imaging Center, Department of Clinical Pathology, Kuopio University Hospital, Kuopio, Finland., Hartman M; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.; Department of Surgery, National University Health System, Singapore, Singapore., He W; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Healey CS; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Heemskerk-Gerritsen BAM; Department of Medical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute, Rotterdam, the Netherlands., Heyworth J; School of Population and Global Health, The University of Western Australia, Perth, Western Australia, Australia., Hillemanns P; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany., Hogervorst FBL; Family Cancer Clinic, The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands., Hollestelle A; Department of Medical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute, Rotterdam, the Netherlands., Hooning MJ; Department of Medical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute, Rotterdam, the Netherlands., Hopper JL; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia., Howell A; Division of Cancer Sciences, University of Manchester, Manchester, UK., Huang G; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany., Hulick PJ; Center for Medical Genetics, NorthShore University HealthSystem, Evanston, IL, USA.; The University of Chicago Pritzker School of Medicine, Chicago, IL, USA., Imyanitov EN; N.N. Petrov Institute of Oncology, St. Petersburg, Russia., Isaacs C; Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA., Iwasaki M; Division of Epidemiology, Center for Public Health Sciences, National Cancer Center, Tokyo, Japan., Jager A; Department of Medical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute, Rotterdam, the Netherlands., Jakimovska M; Research Centre for Genetic Engineering and Biotechnology 'Georgi D. Efremov', Macedonian Academy of Sciences and Arts, Skopje, Republic of North Macedonia., Jakubowska A; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.; Independent Laboratory of Molecular Biology and Genetic Diagnostics, Pomeranian Medical University, Szczecin, Poland., James PA; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, Victoria, Australia.; Parkville Familial Cancer Centre, Peter MacCallum Cancer Center, Melbourne, Victoria, Australia., Janavicius R; Hematology, Oncology and Transfusion Medicine Center, Department of Molecular and Regenerative Medicine, Vilnius University Hospital Santariskiu Clinics, Vilnius, Lithuania.; State Research Institute Centre for Innovative Medicine, Vilnius, Lithuania., Jankowitz RC; Department of Medicine, Division of Hematology/Oncology, UPMC Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., John EM; Department of Medicine, Division of Oncology, Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA, USA., Johnson N; Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK., Jones ME; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK., Jukkola-Vuorinen A; Department of Oncology, Tampere University Hospital, Tampere University and Tampere Cancer Center, Tampere, Finland., Jung A; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Kaaks R; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Kang D; Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea.; Department of Biomedical Sciences, Seoul National University Graduate School, Seoul, Korea.; Cancer Research Institute, Seoul National University, Seoul, Korea., Kapoor PM; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Faculty of Medicine, University of Heidelberg, Heidelberg, Germany., Karlan BY; David Geffen School of Medicine, Department of Obstetrics and Gynecology, University of California, Los Angeles, Los Angeles, CA, USA.; Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Keeman R; Division of Molecular Pathology, Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands., Kerin MJ; Surgery, School of Medicine, National University of Ireland, Galway, Ireland., Khusnutdinova E; Institute of Biochemistry and Genetics, Ufa Federal Research Centre of the Russian Academy of Sciences, Ufa, Russia.; Department of Genetics and Fundamental Medicine, Bashkir State Medical University, Ufa, Russia., Kiiski JI; Department of Obstetrics and Gynecology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland., Kirk J; Familial Cancer Service, Weatmead Hospital, Sydney, New South Wales, Australia., Kitahara CM; Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA., Ko YD; Department of Internal Medicine, Evangelische Kliniken Bonn, Johanniter Krankenhaus, Bonn, Germany., Konstantopoulou I; Molecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research 'Demokritos', Athens, Greece., Kosma VM; Translational Cancer Research Area, University of Eastern Finland, Kuopio, Finland.; Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, Kuopio, Finland.; Imaging Center, Department of Clinical Pathology, Kuopio University Hospital, Kuopio, Finland., Koutros S; Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Kubelka-Sabit K; Department of Histopathology and Cytology, Clinical Hospital 'Acibadem Sistina', Skopje, Republic of North Macedonia., Kwong A; Hong Kong Hereditary Breast Cancer Family Registry, Cancer Genetics Centre, Happy Valley, Hong Kong.; Department of Surgery, The University of Hong Kong, Pok Fu Lam, Hong Kong.; Department of Surgery, Hong Kong Sanatorium and Hospital, Happy Valley, Hong Kong., Kyriacou K; Department of Electron Microscopy/Molecular Pathology and The Cyprus School of Molecular Medicine, The Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus., Laitman Y; The Suzanne Levy-Gertner Oncogenetics Unit, Chaim Sheba Medical Center, Ramat Gan, Israel., Lambrechts D; VIB Center for Cancer Biology, VIB, Leuven, Belgium.; Laboratory for Translational Genetics, Department of Human Genetics, University of Leuven, Leuven, Belgium., Lee E; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Leslie G; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Lester J; David Geffen School of Medicine, Department of Obstetrics and Gynecology, University of California, Los Angeles, Los Angeles, CA, USA.; Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Lesueur F; Institut Curie, Paris, France.; Mines ParisTech, Paris, France.; Genetic Epidemiology of Cancer Team, INSERM U900, Paris, France., Lindblom A; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.; Department of Clinical Genetics, Karolinska University Hospital, Stockholm, Sweden., Lo WY; Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany., Long J; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA., Lophatananon A; Division of Population Health, Health Services Research and Primary Care, School of Health Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK., Loud JT; Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Lubiński J; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland., MacInnis RJ; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia.; Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Victoria, Australia., Maishman T; Southampton Clinical Trials Unit, Faculty of Medicine, University of Southampton, Southampton, UK.; Cancer Sciences Academic Unit, Faculty of Medicine, University of Southampton, Southampton, UK., Makalic E; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia., Mannermaa A; Translational Cancer Research Area, University of Eastern Finland, Kuopio, Finland.; Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, Kuopio, Finland.; Imaging Center, Department of Clinical Pathology, Kuopio University Hospital, Kuopio, Finland., Manoochehri M; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany., Manoukian S; Unit of Medical Genetics, Department of Medical Oncology and Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy., Margolin S; Department of Oncology, Södersjukhuset, Stockholm, Sweden.; Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden., Martinez ME; Moores Cancer Center, University of California, San Diego, La Jolla, CA, USA.; Department of Family Medicine and Public Health, University of California, San Diego, La Jolla, CA, USA., Matsuo K; Division of Cancer Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan.; Division of Cancer Epidemiology, Nagoya University Graduate School of Medicine, Nagoya, Japan., Maurer T; Cancer Epidemiology Group, University Cancer Center Hamburg (UCCH), University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Mavroudis D; Department of Medical Oncology, University Hospital of Heraklion, Heraklion, Greece., Mayes R; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., McGuffog L; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., McLean C; Anatomical Pathology, The Alfred Hospital, Melbourne, Victoria, Australia., Mebirouk N; Institut Curie, Paris, France.; Mines ParisTech, Paris, France.; Department of Tumour Biology, INSERM U830, Paris, France., Meindl A; Department of Gynecology and Obstetrics, University of Munich, Munich, Germany., Miller A; NRG Oncology, Statistics and Data Management Center, Roswell Park Cancer Institute, Buffalo, NY, USA., Miller N; Surgery, School of Medicine, National University of Ireland, Galway, Ireland., Montagna M; Immunology and Molecular Oncology Unit, Veneto Institute of Oncology (IOV), IRCCS, Padua, Italy., Moreno F; Medical Oncology Department, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria San Carlos (IdISSC), Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain., Muir K; Division of Population Health, Health Services Research and Primary Care, School of Health Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK., Mulligan AM; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.; Laboratory Medicine Program, University Health Network, Toronto, Ontario, Canada., Muñoz-Garzon VM; Radiation Oncology, Hospital Meixoeiro-XXI de Vigo, Vigo, Spain., Muranen TA; Department of Obstetrics and Gynecology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland., Narod SA; Women's College Research Institute, University of Toronto, Toronto, Ontario, Canada., Nassir R; Department of Pathology, School of Medicine, Umm Al-Qura University, Holy Makkah, Saudi Arabia., Nathanson KL; Basser Center for BRCA, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA., Neuhausen SL; Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, CA, USA., Nevanlinna H; Department of Obstetrics and Gynecology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland., Neven P; Leuven Multidisciplinary Breast Center, Department of Oncology, Leuven Cancer Institute, University Hospitals Leuven, Leuven, Belgium., Nielsen FC; Center for Genomic Medicine at Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., Nikitina-Zake L; Latvian Biomedical Research and Study Centre, Riga, Latvia., Norman A; Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA., Offit K; Clinical Genetics Research Laboratory, Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Clinical Genetics Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Olah E; Department of Molecular Genetics, National Institute of Oncology, Budapest, Hungary., Olopade OI; Center for Clinical Cancer Genetics, The University of Chicago, Chicago, IL, USA., Olsson H; Department of Cancer Epidemiology, Clinical Sciences, Lund University, Lund, Sweden., Orr N; Centre for Cancer Research and Cell Biology, Queen's University Belfast, Belfast, UK., Osorio A; Centro de Investigación en Biomédica en Red de Enfermedades Raras (CIBERER), Madrid, Spain.; Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain., Pankratz VS; University of New Mexico Health Sciences Center, University of New Mexico, Albuquerque, NM, USA., Papp J; Department of Molecular Genetics, National Institute of Oncology, Budapest, Hungary., Park SK; Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea.; Department of Biomedical Sciences, Seoul National University Graduate School, Seoul, Korea.; Cancer Research Institute, Seoul National University, Seoul, Korea., Park-Simon TW; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany., Parsons MT; Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Paul J; Cancer Research UK Clinical Trials Unit, Institute of Cancer Sciences, University of Glasgow, Glasgow, UK., Pedersen IS; Molecular Diagnostics, Aalborg University Hospital, Aalborg, Denmark.; Clinical Cancer Research Center, Aalborg University Hospital, Aalborg, Denmark.; Department of Clinical Medicine, Aalborg University, Aalborg, Denmark., Peissel B; Unit of Medical Genetics, Department of Medical Oncology and Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy., Peshkin B; Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA., Peterlongo P; Genome Diagnostics Program, IFOM-the FIRC (Italian Foundation for Cancer Research) Institute of Molecular Oncology, Milan, Italy., Peto J; Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK., Plaseska-Karanfilska D; Research Centre for Genetic Engineering and Biotechnology 'Georgi D. Efremov', Macedonian Academy of Sciences and Arts, Skopje, Republic of North Macedonia., Prajzendanc K; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland., Prentice R; Cancer Prevention Program, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Presneau N; School of Life Sciences, University of Westminster, London, UK., Prokofyeva D; Department of Genetics and Fundamental Medicine, Bashkir State Medical University, Ufa, Russia., Pujana MA; ProCURE, Catalan Institute of Oncology, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain., Pylkäs K; Laboratory of Cancer Genetics and Tumor Biology, Cancer and Translational Medicine Research Unit, Biocenter Oulu, University of Oulu, Oulu, Finland.; Laboratory of Cancer Genetics and Tumor Biology, Northern Finland Laboratory Centre Oulu, Oulu, Finland., Radice P; Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Research, Fondazione IRCCS Istituto Nazionale dei Tumori (INT), Milan, Italy., Ramus SJ; School of Women's and Children's Health, Faculty of Medicine, University of New South Wales, Sydney, New South Wales, Australia.; The Kinghorn Cancer Centre, Garvan Institute of Medical Research, Sydney, New South Wales, Australia., Rantala J; Clinical Genetics, Karolinska Institutet, Stockholm, Sweden., Rau-Murthy R; Clinical Genetics Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Rennert G; Clalit National Israeli Cancer Control Center, Carmel Medical Center and Technion Faculty of Medicine, Haifa, Israel., Risch HA; Chronic Disease Epidemiology, Yale School of Public Health, New Haven, CT, USA., Robson M; Clinical Genetics Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Romero A; Medical Oncology Department, Hospital Universitario Puerta de Hierro, Madrid, Spain., Rossing M; Center for Genomic Medicine at Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., Saloustros E; Department of Oncology, University Hospital of Larissa, Larissa, Greece., Sánchez-Herrero E; Medical Oncology Department, Hospital Universitario Puerta de Hierro, Madrid, Spain., Sandler DP; Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, USA., Santamariña M; Centro de Investigación en Biomédica en Red de Enfermedades Raras (CIBERER), Madrid, Spain.; Fundación Pública Galega de Medicina Xenómica, Santiago de Compostela, Spain.; Instituto de Investigación Sanitaria de Santiago de Compostela, Santiago de Compostela, Spain., Saunders C; School of Medicine, University of Western Australia, Perth, Western Australia, Australia., Sawyer EJ; Research Oncology, Guy's Hospital, King's College London, London, UK., Scheuner MT; Cancer Genetics and Prevention Program, University of California, San Francisco, San Francisco, CA, USA., Schmidt DF; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia.; Faculty of Information Technology, Monash University, Melbourne, Victoria, Australia., Schmutzler RK; Center for Hereditary Breast and Ovarian Cancer, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Center for Integrated Oncology (CIO), Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany., Schneeweiss A; Molecular Biology of Breast Cancer, University Womens Clinic Heidelberg, University of Heidelberg, Heidelberg, Germany.; National Center for Tumor Diseases, University Hospital and German Cancer Research Center, Heidelberg, Germany., Schoemaker MJ; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK., Schöttker B; Division of Clinical Epidemiology and Aging Research (C070), German Cancer Research Center (DKFZ), Heidelberg, Germany.; Network Aging Research, University of Heidelberg, Heidelberg, Germany., Schürmann P; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany., Scott C; Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA., Scott RJ; Division of Molecular Medicine, Pathology North, John Hunter Hospital, Newcastle, New South Wales, Australia.; Discipline of Medical Genetics, School of Biomedical Sciences and Pharmacy, Faculty of Health, University of Newcastle, Newcastle, New South Wales, Australia.; Hunter Medical Research Institute, John Hunter Hospital, Newcastle, New South Wales, Australia., Senter L; Clinical Cancer Genetics Program, Division of Human Genetics, Department of Internal Medicine, The Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA., Seynaeve CM; Department of Medical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute, Rotterdam, the Netherlands., Shah M; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Sharma P; Department of Internal Medicine, Division of Medical Oncology, University of Kansas Medical Center, Westwood, KS, USA., Shen CY; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.; School of Public Health, China Medical University, Taichung, Taiwan., Shu XO; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA., Singer CF; Department of Obstetrics and Gynecology and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria., Slavin TP; Clinical Cancer Genomics, City of Hope, Duarte, CA, USA., Smichkoska S; University Clinic of Radiotherapy and Oncology, Medical Faculty, Ss. Cyril and Methodius University in Skopje, Skopje, Republic of North Macedonia., Southey MC; Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Melbourne, Victoria, Australia.; Department of Clinical Pathology, The University of Melbourne, Melbourne, Victoria, Australia., Spinelli JJ; Population Oncology, BC Cancer, Vancouver, British Columbia, Canada.; School of Population and Public Health, University of British Columbia, Vancouver, British Columbia, Canada., Spurdle AB; Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Stone J; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia.; The Curtin UWA Centre for Genetic Origins of Health and Disease, Curtin University and University of Western Australia, Perth, Western Australia, Australia., Stoppa-Lyonnet D; Department of Tumour Biology, INSERM U830, Paris, France.; Service de Génétique, Institut Curie, Paris, France.; Université Paris Descartes, Paris, France., Sutter C; Institute of Human Genetics, University Hospital Heidelberg, Heidelberg, Germany., Swerdlow AJ; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK.; Division of Breast Cancer Research, The Institute of Cancer Research, London, UK., Tamimi RM; Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, MA, USA.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Tan YY; Department of Obstetrics and Gynecology, Medical University of Vienna, Vienna, Austria., Tapper WJ; Faculty of Medicine, University of Southampton, Southampton, UK., Taylor JA; Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, USA.; Epigenetic and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, USA., Teixeira MR; Department of Genetics, Portuguese Oncology Institute, Porto, Portugal.; Biomedical Sciences Institute (ICBAS), University of Porto, Porto, Portugal., Tengström M; Translational Cancer Research Area, University of Eastern Finland, Kuopio, Finland.; Cancer Center, Kuopio University Hospital, Kuopio, Finland.; Institute of Clinical Medicine, Oncology, University of Eastern Finland, Kuopio, Finland., Teo SH; Breast Cancer Research Programme, Cancer Research Malaysia, Kuala Lumpur, Malaysia.; Department of Surgery, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia., Terry MB; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA., Teulé A; Hereditary Cancer Program, ONCOBELL-IDIBELL-IDIBGI-IGTP, Catalan Institute of Oncology, CIBERONC, Barcelona, Spain., Thomassen M; Department of Clinical Genetics, Odense University Hospital, Odence, Denmark., Thull DL; Department of Medicine, Magee-Womens Hospital, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Tischkowitz M; Program in Cancer Genetics, Departments of Human Genetics and Oncology, McGill University, Montréal, Québec, Canada.; Department of Medical Genetics, University of Cambridge, Cambridge, UK., Toland AE; Department of Cancer Biology and Genetics, The Ohio State University, Columbus, OH, USA., Tollenaar RAEM; Department of Surgery, Leiden University Medical Center, Leiden, the Netherlands., Tomlinson I; Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UK.; Wellcome Trust Centre for Human Genetics and NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK., Torres D; Institute of Human Genetics, Pontificia Universidad Javeriana, Bogota, Colombia.; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany., Torres-Mejía G; Center for Population Health Research, National Institute of Public Health, Cuernavaca, Mexico., Troester MA; Department of Epidemiology, Gillings School of Global Public Health and UNC Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Truong T; Cancer and Environment Group, Center for Research in Epidemiology and Population Health (CESP), INSERM, University Paris-Sud, University Paris-Saclay, Paris, France., Tung N; Department of Medical Oncology, Beth Israel Deaconess Medical Center, Boston, MA, USA., Tzardi M; Department of Pathology, University Hospital of Heraklion, Heraklion, Greece., Ulmer HU; Frauenklinik der Stadtklinik Baden-Baden, Baden-Baden, Germany., Vachon CM; Department of Health Science Research, Division of Epidemiology, Mayo Clinic, Rochester, MN, USA., van Asperen CJ; Department of Clinical Genetics, Leiden University Medical Center, Leiden, the Netherlands., van der Kolk LE; Family Cancer Clinic, The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands., van Rensburg EJ; Department of Genetics, University of Pretoria, Pretoria, South Africa., Vega A; Fundación Pública Galega de Medicina Xenómica-SERGAS, Grupo de Medicina Xenómica-USC, CIBERER, IDIS, Santiago de Compostela, Spain., Viel A; Division of Functional Onco-genomics and Genetics, Centro di Riferimento Oncologico di Aviano (CRO), IRCCS, Aviano, Italy., Vijai J; Clinical Genetics Research Laboratory, Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Clinical Genetics Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Vogel MJ; Family Cancer Clinic, The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands., Wang Q; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Wappenschmidt B; Center for Hereditary Breast and Ovarian Cancer, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Center for Integrated Oncology (CIO), Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany., Weinberg CR; Biostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, USA., Weitzel JN; Clinical Cancer Genomics, City of Hope, Duarte, CA, USA., Wendt C; Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden., Wildiers H; Leuven Multidisciplinary Breast Center, Department of Oncology, Leuven Cancer Institute, University Hospitals Leuven, Leuven, Belgium., Winqvist R; Laboratory of Cancer Genetics and Tumor Biology, Cancer and Translational Medicine Research Unit, Biocenter Oulu, University of Oulu, Oulu, Finland.; Laboratory of Cancer Genetics and Tumor Biology, Northern Finland Laboratory Centre Oulu, Oulu, Finland., Wolk A; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.; Department of Surgical Sciences, Uppsala University, Uppsala, Sweden., Wu AH; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Yannoukakos D; Molecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research 'Demokritos', Athens, Greece., Zhang Y; Division of Clinical Epidemiology and Aging Research (C070), German Cancer Research Center (DKFZ), Heidelberg, Germany.; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany., Zheng W; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA., Hunter D; Nuffield Department of Population Health, University of Oxford, Oxford, UK., Pharoah PDP; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Chang-Claude J; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Cancer Epidemiology Group, University Cancer Center Hamburg (UCCH), University Medical Center Hamburg-Eppendorf, Hamburg, Germany., García-Closas M; Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.; Division of Genetics and Epidemiology, Institute of Cancer Research, London, UK., Schmidt MK; Division of Molecular Pathology, Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands.; Division of Psychosocial Research and Epidemiology, The Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands., Milne RL; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia.; Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Victoria, Australia.; Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Melbourne, Victoria, Australia., Kristensen VN; Department of Cancer Genetics, Institute for Cancer Research, Oslo University Hospital-Radiumhospitalet, Oslo, Norway.; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.; The Hereditary Breast and Ovarian Cancer Research Group Netherlands (HEBON) Coordinating Center, The Netherlands Cancer Institute, Amsterdam, the Netherlands.; Australian Breast Cancer Tissue Bank, Westmead Institute for Medical Research, University of Sydney, Sydney, New South Wales, Australia., French JD; Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Edwards SL; Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Antoniou AC; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Chenevix-Trench G; Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Simard J; Genomics Center, Centre Hospitalier Universitaire de Québec, Université Laval Research Center, Québec City, Québec, Canada., Easton DF; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Kraft P; Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, MA, USA. pkraft@hsph.harvard.edu.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA. pkraft@hsph.harvard.edu., Dunning AM; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK. amd24@medschl.cam.ac.uk.

مؤلفون مشاركون: GEMO Study Collaborators, EMBRACE Collaborators, KConFab Investigators, HEBON Investigators, ABCTB Investigators

المصدر: Nature genetics [Nat Genet] 2020 Jan; Vol. 52 (1), pp. 56-73. Date of Electronic Publication: 2020 Jan 07.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE

مواضيع طبية MeSH: Genetic Predisposition to Disease* , Genome-Wide Association Study* , Polymorphism, Single Nucleotide* , Quantitative Trait Loci*, Biomarkers, Tumor/*genetics , Breast Neoplasms/*genetics , Chromosome Mapping/*methods, Bayes Theorem ; Female ; Humans ; Linkage Disequilibrium ; Regulatory Sequences, Nucleic Acid ; Risk Factors

المؤلفون: Gudmundsson J; deCODE genetics/AMGEN, 101, Reykjavik, Iceland. julius.gudmundsson@decode.is., Sigurdsson JK; deCODE genetics/AMGEN, 101, Reykjavik, Iceland., Stefansdottir L; deCODE genetics/AMGEN, 101, Reykjavik, Iceland., Agnarsson BA; Landspitali-University Hospital, 101, Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, 101, Reykjavik, Iceland., Isaksson HJ; Landspitali-University Hospital, 101, Reykjavik, Iceland., Stefansson OA; deCODE genetics/AMGEN, 101, Reykjavik, Iceland., Gudjonsson SA; deCODE genetics/AMGEN, 101, Reykjavik, Iceland., Gudbjartsson DF; deCODE genetics/AMGEN, 101, Reykjavik, Iceland.; School of Engineering and Natural Sciences, University of Iceland, 101, Reykjavik, Iceland., Masson G; deCODE genetics/AMGEN, 101, Reykjavik, Iceland., Frigge ML; deCODE genetics/AMGEN, 101, Reykjavik, Iceland., Stacey SN; deCODE genetics/AMGEN, 101, Reykjavik, Iceland., Sulem P; deCODE genetics/AMGEN, 101, Reykjavik, Iceland., Halldorsson GH; deCODE genetics/AMGEN, 101, Reykjavik, Iceland., Tragante V; deCODE genetics/AMGEN, 101, Reykjavik, Iceland.; Department of Cardiology, Division Heart & Lungs, University Medical Center Utrecht, University of Utrecht, 3584 CX, Utrecht, The Netherlands., Holm H; deCODE genetics/AMGEN, 101, Reykjavik, Iceland., Eyjolfsson GI; The Clinical Laboratory in Mjodd, 109, Reykjavik, Iceland., Sigurdardottir O; Department of Clinical Biochemistry, Akureyri Hospital, 600, Akureyri, Iceland., Olafsson I; Landspitali-University Hospital, 101, Reykjavik, Iceland., Jonsson T; Landspitali-University Hospital, 101, Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, 101, Reykjavik, Iceland., Jonsson E; Landspitali-University Hospital, 101, Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, 101, Reykjavik, Iceland., Barkardottir RB; Laboratory of Cell Biology, Department of Pathology, Landspitali University Hospital, 101, Reykjavik, Iceland.; Biomedical Centre, Faculty of Medicine, University of Iceland, 101, Reykjavik, Iceland., Hilmarsson R; Landspitali-University Hospital, 101, Reykjavik, Iceland., Asselbergs FW; Department of Cardiology, Division Heart & Lungs, University Medical Center Utrecht, University of Utrecht, 3584 CX, Utrecht, The Netherlands.; Durrer Center for Cardiovascular Research, Netherlands Heart Institute, 3511 EP, Utrecht, The Netherlands.; Institute of Cardiovascular Science, Faculty of Population Health Sciences, University College London, London, WC1E 6BT, UK.; Farr Institute of Health Informatics Research and Institute of Health Informatics, University College London, London, NW1 2DA, UK., Geirsson G; Landspitali-University Hospital, 101, Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, 101, Reykjavik, Iceland., Thorsteinsdottir U; deCODE genetics/AMGEN, 101, Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, 101, Reykjavik, Iceland., Rafnar T; deCODE genetics/AMGEN, 101, Reykjavik, Iceland., Thorleifsson G; deCODE genetics/AMGEN, 101, Reykjavik, Iceland., Stefansson K; deCODE genetics/AMGEN, 101, Reykjavik, Iceland. kstefans@decode.is.; Faculty of Medicine, University of Iceland, 101, Reykjavik, Iceland. kstefans@decode.is.

المصدر: Nature communications [Nat Commun] 2018 Nov 08; Vol. 9 (1), pp. 4568. Date of Electronic Publication: 2018 Nov 08.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Genome-Wide Association Study*, Prostate-Specific Antigen/*blood , Prostatic Hyperplasia/*blood , Prostatic Hyperplasia/*genetics, Acetylation ; Aged ; Computational Biology ; Genetic Predisposition to Disease ; Histones/metabolism ; Humans ; Iceland ; Lower Urinary Tract Symptoms/blood ; Lower Urinary Tract Symptoms/genetics ; Lysine/metabolism ; Male ; Meta-Analysis as Topic ; Multifactorial Inheritance/genetics ; Mutation/genetics ; Phenotype ; Quantitative Trait Loci/genetics ; Risk Factors ; United Kingdom

المؤلفون: Lu Y; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee., Beeghly-Fadiel A; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee., Wu L; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee., Guo X; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee., Li B; Department of Molecular Physiology and Biophysics, Vanderbilt University Medical Center, Nashville, Tennessee., Schildkraut JM; Department of Public Health Sciences, University of Virginia, Charlottesville, Virginia., Im HK; Section of Genetic Medicine, Department of Medicine, University of Chicago, Chicago, Illinois., Chen YA; Department of Biostatistics, Moffitt Cancer Center, Tampa, Florida., Permuth JB; Department of Cancer Epidemiology, Moffitt Cancer Center, Tampa, Florida., Reid BM; Department of Cancer Epidemiology, Moffitt Cancer Center, Tampa, Florida., Teer JK; Department of Biostatistics, Moffitt Cancer Center, Tampa, Florida., Moysich KB; Division of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, New York., Andrulis IL; Fred A. Litwin Center for Cancer Genetics, Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada., Anton-Culver H; Department of Epidemiology, Genetic Epidemiology Research Institute, University of California Irvine, Irvine, California., Arun BK; Department of Breast Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas., Bandera EV; Cancer Prevention and Control Program, Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey., Barkardottir RB; Department of Pathology, Landspitali University Hospital, Reykjavik, Iceland.; BMC (Biomedical Centre), Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Barnes DR; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom., Benitez J; Human Cancer Genetics Program, Spanish National Cancer Research Centre, Madrid, Spain.; Centro de Investigación en Red de Enfermedades Raras (CIBERER), Valencia, Spain., Bjorge L; Department of Gynecology and Obstetrics, Haukeland University Horpital, Bergen, Norway.; Centre for Cancer Biomarkers, Department of Clinical Science, University of Bergen, Bergen, Norway., Brenton J; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, United Kingdom., Butzow R; Department of Pathology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Caldes T; Medical Oncology Department, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria San Carlos (IdISSC), Centro Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain., Caligo MA; Section of Genetic Oncology, Department of Laboratory Medicine, University and University Hospital of Pisa, Pisa, Italy., Campbell I; Peter MacCallum Cancer Center, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, Victoria, Australia.; Department of Pathology, The University of Melbourne, Melbourne, Victoria, Australia., Chang-Claude J; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Research Group Genetic Cancer Epidemiology, University Cancer Center Hamburg (UCCH), University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Claes KBM; Centre for Medical Genetics, Ghent University, Gent, Belgium., Couch FJ; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota., Cramer DW; Obstetrics and Gynecology Epidemiology Center, Brigham and Women's Hospital, Boston, Massachusetts.; Harvard T.H. Chan School of Public Health, Boston, Massachusetts., Daly MB; Department of Clinical Genetics, Fox Chase Cancer Center, Philadelphia, Pennsylvania., deFazio A; Centre for Cancer Research, The Westmead Institute for Medical Research, The University of Sydney, Sydney, New South Wales, Australia.; Department of Gynaecological Oncology, Westmead Hospital, Sydney, New South Wales, Australia., Dennis J; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom., Diez O; Oncogenetics Group, Clinical and Molecular Genetics Area, Vall d'Hebron Institute of Oncology (VHIO), University Hospital, Vall d'Hebron, Barcelona, Spain., Domchek SM; Department of Medicine, Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania., Dörk T; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany., Easton DF; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, United Kingdom., Eccles DM; Cancer Sciences Academic Unit, Faculty of Medicine, University of Southampton, Southampton, United Kingdom., Fasching PA; Department of Gynaecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, Erlangen, Germany.; David Geffen School of Medicine, Department of Medicine Division of Hematology and Oncology, University of California at Los Angeles, Los Angeles, California., Fortner RT; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Fountzilas G; Department of Medical Oncology, 'Papageorgiou' Hospital, Aristotle University of Thessaloniki School of Medicine, Thessaloniki, Greece., Friedman E; The Susanne Levy Gertner Oncogenetics Unit, Chaim Sheba Medical Center, Ramat Gan, Israel.; Sackler Faculty of Medicine, Tel Aviv University, Ramat Aviv, Israel., Ganz PA; Schools of Medicine and Public Health, Division of Cancer Prevention & Control Research, Jonsson Comprehensive Cancer Centre, UCLA, Los Angeles, California., Garber J; Cancer Risk and Prevention Clinic, Dana-Farber Cancer Institute, Boston, Massachusetts., Giles GG; Cancer Epidemiology & Intelligence Division, Cancer Council Victoria, Melbourne, Victoria, Australia.; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia.; Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia., Godwin AK; Department of Pathology and Laboratory Medicine, Kansas University Medical Center, Kansas City, Kansas., Goldgar DE; Department of Dermatology, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, Utah., Goodman MT; Cancer Prevention and Control, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California.; Community and Population Health Research Institute, Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California., Greene MH; Clinical Genetics Branch, DCEG, National Cancer Institute, Bethesda, Maryland., Gronwald J; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland., Hamann U; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany., Heitz F; Department of Gynecology and Gynecologic Oncology, Dr. Horst Schmidt Kliniken Wiesbaden, Wiesbaden, Germany.; Department of Gynecology and Gynecologic Oncology, Kliniken Essen-Mitte/Evang. Huyssens-Stiftung/Knappschaft GmbH, Essen, Germany., Hildebrandt MAT; Department of Epidemiology, University of Texas MD Anderson Cancer Center, Houston, Texas., Høgdall CK; Department of Gynecology, The Juliane Marie Centre, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark., Hollestelle A; Department of Medical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute, Rotterdam, The Netherlands., Hulick PJ; Center for Medical Genetics, NorthShore University HealthSystem, Evanston, Illinois.; The University of Chicago Pritzker School of Medicine, Chicago, Illinois., Huntsman DG; British Columbia's Ovarian Cancer Research (OVCARE) Program, Vancouver General Hospital, BC Cancer Agency and University of British Columbia, Vancouver, British Columbia, Canada.; Department of Molecular Oncology, BC Cancer Agency Research Centre, Vancouver, British Columbia, Canada.; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada., Imyanitov EN; N.N. Petrov Institute of Oncology, St. Petersburg, Russia., Isaacs C; Lombardi Comprehensive Cancer Center, Georgetown University, Washington, District of Columbia., Jakubowska A; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland., James P; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, Victoria, Australia.; Parkville Familial Cancer Centre, Peter MacCallum Cancer Center, Melbourne, Victoria, Australia., Karlan BY; Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California., Kelemen LE; Department of Public Health Sciences, Medical University of South Carolina, Charleston, South Carolina., Kiemeney LA; Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, The Netherlands., Kjaer SK; Department of Virus, Lifestyle and Genes, Danish Cancer Society Research Center, Copenhagen, Denmark.; Department of Gynaecology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark., Kwong A; Hong Kong Hereditary Breast Cancer Family Registry, Happy Valley, Hong Kong.; Department of Surgery, The University of Hong Kong, Pok Fu Lam, Hong Kong.; Department of Surgery, Hong Kong Sanatorium and Hospital, Happy Valley, Hong Kong., Le ND; Cancer Control Research, BC Cancer Agency, Vancouver, British Columbia, Canada., Leslie G; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom., Lesueur F; Genetic Epidemiology of Cancer team, Inserm U900, Paris, France.; Institut Curie, Paris, France.; PSL University, Paris, France.; Mines ParisTech, Fontainebleau, France., Levine DA; Gynecology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.; Gynecologic Oncology, Laura and Isaac Pearlmutter Cancer Center, NYU Langone Medical Center, New York, New York., Mattiello A; Dipertimento Di Medicina Clinica E Chirurgia, Federico II University, Naples, Italy., May T; Division of Gynecologic Oncology, University Health Network, Princess Margaret Hospital, Toronto, Ontario, Canada., McGuffog L; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom., McNeish IA; Institute of Cancer Sciences, University of Glasgow, Wolfson Wohl Cancer Research Centre, Glasgow, United Kingdom., Merritt MA; Cancer Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii.; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom., Modugno F; Ovarian Cancer Center of Excellence, Womens Cancer Research Program, Magee-Womens Research Institute and University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania.; Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania.; Division of Gynecologic Oncology, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania., Montagna M; Immunology and Molecular Oncology Unit, Veneto Institute of Oncology IOV - IRCCS, Padua, Italy., Neuhausen SL; Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, California., Nevanlinna H; Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Nielsen FC; Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., Nikitina-Zake L; Latvian Biomedical Research and Study Centre, Riga, Latvia., Nussbaum RL; Cancer Genetics and Prevention Program, University of California San Francisco, San Francisco, California., Offit K; Clinical Genetics Research Lab, Department of Cancer Biology and Genetics, Memorial Sloan-Kettering Cancer Center, New York, New York.; Clinical Genetics Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York., Olah E; Department of Molecular Genetics, National Institute of Oncology, Budapest, Hungary., Olopade OI; Center for Clinical Cancer Genetics, The University of Chicago, Chicago, Illinois., Olson SH; Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, New York., Olsson H; Department of Cancer Epidemiology, Clinical Sciences, Lund University, Lund, Sweden., Osorio A; Human Cancer Genetics Program, Spanish National Cancer Research Centre, Madrid, Spain.; Biomedical Network on Rare Diseases (CIBERER), Madrid, Spain., Park SK; Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea.; Department of Biomedical Sciences, Seoul National University Graduate School, Seoul, Korea.; Cancer Research Institute, Seoul National University, Seoul, Korea., Parsons MT; Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Peeters PHM; Julius Center for Health Sciences and Primary Care, UMC Utrecht, University Utrecht, Utrecht, The Netherlands., Pejovic T; Department of Obstetrics and Gynecology, Oregon Health & Science University, Portland, Oregon.; Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon., Peterlongo P; IFOM, the FIRC (Italian Foundation for Cancer Research) Institute of Molecular Oncology, Milan, Italy., Phelan CM; Department of Cancer Epidemiology, Moffitt Cancer Center, Tampa, Florida., Pujana MA; Catalan Institute of Oncology, ProCURE, Oncobell, Bellvitge Biomedical Research Institute (IDIBELL). Barcelona, Spain., Ramus SJ; School of Women's and Children's Health, University of NSW Sydney, Sydney, New South Wales, Australia.; The Kinghorn Cancer Centre, Garvan Institute of Medical Research, Sydney, New South Wales, Australia., Rennert G; Clalit National Cancer Control Center, Carmel Medical Center and Technion Faculty of Medicine, Haifa, Israel., Risch H; School of Public Health, Yale University, New Haven, Connecticut., Rodriguez GC; Division of Gynecologic Oncology, NorthShore University HealthSystem, University of Chicago, Evanston, Illinois., Rodríguez-Antona C; Hereditary Endocrine Cancer group, Spanish National Cancer Research Center (CNIO), Madrid, Spain., Romieu I; Nutrition and Metabolism Section, International Agency for Research on Cancer (IARC-WHO), Lyon, France., Rookus MA; Department of Epidemiology, The Netherlands Cancer Institute, Amsterdam, The Netherlands., Rossing MA; Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington.; Department of Epidemiology, University of Washington, Seattle, Washington., Rzepecka IK; Department of Pathology and Laboratory Diagnostics, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland., Sandler DP; Epidemiology Branch, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, Maryland., Schmutzler RK; Center for Hereditary Breast and Ovarian Cancer, University Hospital of Cologne, Cologne, Germany.; Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany., Setiawan VW; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California., Sharma P; Department of Medicine, University of Kansas Medical Center, Kansas City, Kansas., Sieh W; Department of Genetics and Genomic Sciences, Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, New York., Simard J; Genomics Center, Centre Hospitalier Universitaire de Québec Research Center, Laval University, Québec City, Québec, Canada., Singer CF; Dept of OB/GYN and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria., Song H; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, United Kingdom., Southey MC; Department of Pathology, The University of Melbourne, Melbourne, Victoria, Australia., Spurdle AB; Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Sutphen R; Epidemiology Center, College of Medicine, University of South Florida, Tampa, Florida., Swerdlow AJ; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, United Kingdom.; Division of Breast Cancer Research, The Institute of Cancer Research, London, United Kingdom., Teixeira MR; Department of Genetics, Portuguese Oncology Institute, Porto, Portugal.; Biomedical Sciences Institute (ICBAS), University of Porto, Porto, Portugal., Teo SH; Cancer Research Malaysia, Subang Jaya, Selangor, Malaysia.; Breast Cancer Research Unit, Cancer Research Institute, University Malaya Medical Centre, Kuala Lumpur, Malaysia., Thomassen M; Department of Clinical Genetics, Odense University Hospital, Odence C, Denmark., Tischkowitz M; Program in Cancer Genetics, Departments of Human Genetics and Oncology, McGill University, Montréal, Québec, Canada.; Department of Medical Genetics, Cambridge University, Cambridge, United Kingdom., Toland AE; Department of Cancer Biology and Genetics, Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio., Trichopoulou A; Hellenic Health Foundation, Athens, Greece.; WHO Collaborating Center for Nutrition and Health, Unit of Nutritional Epidemiology and Nutrition in Public Health, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School, Athens, Greece., Tung N; Department of Medical Oncology, Beth Israel Deaconess Medical Center, Boston, Massachusetts., Tworoger SS; Department of Cancer Epidemiology, Moffitt Cancer Center, Tampa, Florida.; Research Institute and Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts., van Rensburg EJ; Department of Genetics, University of Pretoria, Arcadia, South Africa., Vanderstichele A; Division of Gynecologic Oncology, Department of Obstetrics and Gynaecology and Leuven Cancer Institute, University Hospitals Leuven, Leuven, Belgium., Vega A; Fundación Pública Galega Medicina Xenómica, Santiago De Compostela, Spain., Edwards DV; Vanderbilt Epidemiology Center, Vanderbilt Genetics Institute, Department of Obstetrics and Gynecology, Vanderbilt University Medical Center, Nashville, Tennessee., Webb PM; Population Health Department, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Weitzel JN; Clinical Cancer Genetics, City of Hope, Duarte, California., Wentzensen N; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland., White E; Fred Hutchinson Cancer Research Center, Seattle, Washington.; Department of Epidemiology, University of Washington, Seattle, Washington., Wolk A; Department of Environmental Medicine, Division of Nutritional Epidemiology, Karolinska Institutet, Stockholm, Sweden., Wu AH; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California., Yannoukakos D; Molecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research 'Demokritos', Athens, Greece., Zorn KK; Magee-Womens Hospital, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania., Gayther SA; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California.; Center for Cancer Prevention and Translational Genomics, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California.; Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California., Antoniou AC; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom., Berchuck A; Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, North Carolina., Goode EL; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota., Chenevix-Trench G; Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Sellers TA; Department of Cancer Epidemiology, Moffitt Cancer Center, Tampa, Florida., Pharoah PDP; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, United Kingdom., Zheng W; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee., Long J; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee. jirong.long@vanderbilt.edu.

المصدر: Cancer research [Cancer Res] 2018 Sep 15; Vol. 78 (18), pp. 5419-5430. Date of Electronic Publication: 2018 Jul 27.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Genetic Predisposition to Disease* , Genome-Wide Association Study* , Transcriptome*, Carcinoma, Ovarian Epithelial/*genetics , Ovarian Neoplasms/*genetics, Carcinogenesis ; Cohort Studies ; Female ; Gene Expression Profiling ; Genotype ; Humans ; Polymorphism, Single Nucleotide ; Prognosis ; Quantitative Trait Loci ; Risk Factors

المؤلفون: Bjornsson T; deCODE genetics/Amgen, Inc., Sturlugata 8, Reykjavik, Iceland., Thorolfsdottir RB; deCODE genetics/Amgen, Inc., Sturlugata 8, Reykjavik, Iceland., Sveinbjornsson G; deCODE genetics/Amgen, Inc., Sturlugata 8, Reykjavik, Iceland., Sulem P; deCODE genetics/Amgen, Inc., Sturlugata 8, Reykjavik, Iceland., Norddahl GL; deCODE genetics/Amgen, Inc., Sturlugata 8, Reykjavik, Iceland., Helgadottir A; deCODE genetics/Amgen, Inc., Sturlugata 8, Reykjavik, Iceland., Gretarsdottir S; deCODE genetics/Amgen, Inc., Sturlugata 8, Reykjavik, Iceland., Magnusdottir A; deCODE genetics/Amgen, Inc., Sturlugata 8, Reykjavik, Iceland., Danielsen R; Department of Medicine, Landspitali-The National University Hospital of Iceland, Hringbraut, Reykjavik, Iceland., Sigurdsson EL; Department of Family Medicine, University of Iceland, Vatnsmyrarvegur 16, Reykjavik, Iceland.; Department of Development, Primary Health Care of the Capital Area, Alfabakki 16, Reykjavik, Iceland., Adalsteinsdottir B; Department of Cardiology, Haukeland University Hospital, Jonas Lies vei 83, Bergen, Norway.; Faculty of Medicine, University of Iceland, Vatnsmyrarvegur 16, Reykjavik, Iceland., Gunnarsson SI; Division of Cardiovascular Medicine, Department of Medicine, University of Wisconsin, 600 Highland Ave, Madison, WI, USA., Jonsdottir I; deCODE genetics/Amgen, Inc., Sturlugata 8, Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Vatnsmyrarvegur 16, Reykjavik, Iceland.; Department of Immunology, Landspitali-The National University Hospital of Iceland, Hringbraut, Reykjavik, Iceland., Arnar DO; deCODE genetics/Amgen, Inc., Sturlugata 8, Reykjavik, Iceland.; Department of Medicine, Landspitali-The National University Hospital of Iceland, Hringbraut, Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Vatnsmyrarvegur 16, Reykjavik, Iceland., Helgason H; Children's Hospital, Landspitali-The National University Hospital of Iceland, Hringbraut, Reykjavik, Iceland., Gudbjartsson T; Faculty of Medicine, University of Iceland, Vatnsmyrarvegur 16, Reykjavik, Iceland.; Department of Cardiothoracic Surgery, Landspitali-The National University Hospital of Iceland, Hringbraut, Reykjavik, Iceland., Gudbjartsson DF; deCODE genetics/Amgen, Inc., Sturlugata 8, Reykjavik, Iceland.; School of Engineering and Natural Sciences, University of Iceland, Hjardarhagi 4, Reykjavik, Iceland., Thorsteinsdottir U; deCODE genetics/Amgen, Inc., Sturlugata 8, Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Vatnsmyrarvegur 16, Reykjavik, Iceland., Holm H; deCODE genetics/Amgen, Inc., Sturlugata 8, Reykjavik, Iceland., Stefansson K; deCODE genetics/Amgen, Inc., Sturlugata 8, Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Vatnsmyrarvegur 16, Reykjavik, Iceland.

المصدر: European heart journal [Eur Heart J] 2018 Sep 07; Vol. 39 (34), pp. 3243-3249.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 8006263 Publication Model: Print Cited Medium: Internet ISSN: 1522-9645 (Electronic) Linking ISSN: 0195668X NLM ISO Abbreviation: Eur Heart J Subsets: MEDLINE

مواضيع طبية MeSH: Genetic Predisposition to Disease* , Genome-Wide Association Study* , Mutation, Missense*, Aortic Coarctation/*genetics , Cardiac Myosins/*genetics , DNA/*genetics , Myosin Heavy Chains/*genetics, Adolescent ; Adult ; Aortic Coarctation/metabolism ; Asymptomatic Diseases ; Cardiac Myosins/metabolism ; Child ; Child, Preschool ; DNA Mutational Analysis ; Female ; Humans ; Infant ; Infant, Newborn ; Male ; Myosin Heavy Chains/metabolism ; Pedigree ; Retrospective Studies ; Young Adult

المؤلفون: Couch FJ; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA.; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, USA., Kuchenbaecker KB; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK., Michailidou K; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK., Mendoza-Fandino GA; Cancer Epidemiology Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida 33612, USA., Nord S; Department of Genetics, Institute for Cancer Research, Oslo University Hospital, Radiumhospitalet, N-0310 Oslo, Norway., Lilyquist J; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, USA., Olswold C; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, USA., Hallberg E; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, USA., Agata S; Immunology and Molecular Oncology Unit, Istituto Oncologico Veneto IOV-IRCCS, 20133 Padua, Italy., Ahsan H; Department of Health Studies, The University of Chicago, Chicago, Illinois 60637, USA.; Comprehensive Cancer Center, The University of Chicago, Chicago, Illinois 60637, USA.; Departments of Medicine and Human Genetics, The University of Chicago, Chicago, Illinois 60637, USA., Aittomäki K; Department of Clinical Genetics, Helsinki University Central Hospital, 00029 Helsinki, Finland., Ambrosone C; Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, New York 14263, USA., Andrulis IL; Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada M5G 1X5.; Departments of Molecular Genetics and Laboratory Medicine and Pathobiology, University of Toronto, Ontario, Canada M5B 1W8., Anton-Culver H; Department of Epidemiology, University of California Irvine, Irvine, California, 92697, USA., Arndt V; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany., Arun BK; University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA., Arver B; Department of Oncology, Karolinska University Hospital, SE-17176 Stockholm, Sweden., Barile M; Division of Cancer Prevention and Genetics, Istituto Europeo di Oncologia, 20141 Milan, Italy., Barkardottir RB; Department of Pathology, Landspitali University Hospital and University of Iceland School of Medicine, 101 Reykjavik, Iceland., Barrowdale D; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK., Beckmann L; Institute for Quality and Efficiency in Health Care (IQWiG), 50670 Cologne, Germany., Beckmann MW; University Breast Center Franconia, Department of Gynecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, 91054 Erlangen, Germany., Benitez J; Human Genetics Group, Human Cancer Genetics Program, Spanish National Cancer Centre (CNIO), 28029 Madrid, Spain.; Genotyping Unit (CeGen), Human Cancer Genetics Program, Spanish National Cancer Centre (CNIO), 28029 Madrid, Spain.; Biomedical Network on Rare Diseases (CIBERER), 28029 Madrid, Spain., Blank SV; NYU Women's Cancer Program, New York University School of Medicine, New York, New York 10016, USA., Blomqvist C; Department of Oncology, University of Helsinki and Helsinki University Central Hospital, FI-00029 Helsinki, Finland., Bogdanova NV; Department of Radiation Oncology, Hannover Medical School, 30625 Hannover, Germany., Bojesen SE; Copenhagen General Population Study, Herlev Hospital, Copenhagen University Hospital, 2730 Herlev, Denmark., Bolla MK; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK., Bonanni B; Division of Cancer Prevention and Genetics, Istituto Europeo di Oncologia, 20141 Milan, Italy., Brauch H; Dr Margarete Fischer-Bosch-Institute of Clinical Pharmacology, 70376 Stuttgart, Germany.; University of Tübingen 72074 Tübingen, Germany., Brenner H; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.; Division of Preventive Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), 69120 Heidelberg, Germany., Burwinkel B; Department of Obstetrics and Gynecology, University of Heidelberg, 69120 Heidelberg, Germany., Buys SS; Department of Medicine, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City Utah 84112, USA., Caldes T; Molecular Oncology Laboratory, Hospital Clinico San Carlos, IdISSC, Madrid 28040, Spain., Caligo MA; Section of Genetic Oncology, Department of Laboratory Medicine, University and University Hospital of Pisa, I-56126 Pisa, Italy., Canzian F; Genomic Epidemiology Group, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany., Carpenter J; Australian Breast Cancer Tissue Bank, Westmead Millennium Institute, University of Sydney, Sydney, New South Wales 2145, Australia., Chang-Claude J; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany., Chanock SJ; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland 20850, USA., Chung WK; Departments of Pediatrics and Medicine, Columbia University, New York, New York 10032, USA., Claes KB; Center for Medical Genetics, Ghent University, 9000 Ghent, Belgium., Cox A; Sheffield Cancer Research Centre, Department of Oncology, University of Sheffield, Sheffield S10 2RX, UK., Cross SS; Academic Unit of Pathology, Department of Neuroscience, University of Sheffield, Sheffield S10 2HQ, UK., Cunningham JM; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA., Czene K; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, SE-17177 Stockholm, Sweden., Daly MB; Department of Clinical Genetics, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA., Damiola F; INSERM U1052, CNRS UMR5286, Université Lyon, Centre de Recherche en Cancérologie de Lyon, 69373 Lyon, France., Darabi H; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, SE-17177 Stockholm, Sweden., de la Hoya M; Molecular Oncology Laboratory, Hospital Clinico San Carlos, IdISSC, Madrid 28040, Spain., Devilee P; Department of Human Genetics and Department of Pathology, Leiden University Medical Center, Leiden 2333 ZC, The Netherlands., Diez O; Oncogenetics Group, University Hospital Vall d'Hebron, Vall d'Hebron Institute of Oncology (VHIO) and Universitat Autònoma de Barcelona, 08035 Barcelona, Spain., Ding YC; Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, California 91010, USA., Dolcetti R; Cancer Bioimmunotherapy Unit, CRO Aviano National Cancer Institute, 33081 Aviano , Italy., Domchek SM; Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Pennsylvania 19104, USA., Dorfling CM; Department of Genetics, University of Pretoria, Pretoria 0007, South Africa., Dos-Santos-Silva I; Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, WC1E 7HT, UK., Dumont M; Cancer Genomics Laboratory, Centre Hospitalier Universitaire de Québec and Laval University, Quebec City, Quebec, Canada G1V 4G2., Dunning AM; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge CB1 8RN, UK., Eccles DM; Faculty of Medicine, University of Southampton, University Hospital Southampton, Southampton, Hampshire SO16 6YD, UK., Ehrencrona H; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala SE-751 85, Sweden.; Department of Clinical Genetics, Lund University Hospital, SE-22185 Lund, Sweden., Ekici AB; Institute of Human Genetics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, 91054 Erlangen, Germany.; Comprehensive Cancer Center -EMN, 91054 Erlangen, Germany., Eliassen H; Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA., Ellis S; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK., Fasching PA; University Breast Center Franconia, Department of Gynecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, 91054 Erlangen, Germany., Figueroa J; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland 20850, USA., Flesch-Janys D; Department of Cancer Epidemiology/Clinical Cancer Registry and Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, 20246 Hamburg, Germany., Försti A; Division of Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.; Center for Primary Health Care Research, Lund University, SE-221 00 Malmö, Sweden., Fostira F; Molecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research 'Demokritos', Aghia Paraskevi Attikis, 15310 Athens, Greece., Foulkes WD; Program in Cancer Genetics, McGill University, Montreal, Quebec, Canada H3A 0G4., Friebel T; University of, Philadelphia, Pennsylvania 19104, USA., Friedman E; Susanne Levy Gertner Oncogenetics Unit, Sheba Medical Center, Tel-Hashomer 52621, Israel., Frost D; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK., Gabrielson M; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, SE-17177 Stockholm, Sweden., Gammon MD; Department of Epidemiology, University of, Chapel Hill, North Carolina 27599-7400, USA., Ganz PA; UCLA Schools of Medicine and Public Health, Division of Cancer Prevention and Control Research, Jonsson Comprehensive Cancer Center, Los Angeles, California 90095-6900, USA., Gapstur SM; Epidemiology Research Program, American Cancer Society, Atlanta, Georgia 30303, USA., Garber J; Cancer Risk and Prevention Clinic, Dana Farber Cancer Institute, Boston, Massachusetts 02215, USA., Gaudet MM; Epidemiology Research Program, American Cancer Society, Atlanta, Georgia 30303, USA., Gayther SA; Department of Biomedical Sciences, Cedars Sinai Medical Center, Los Angeles, California 90048, USA., Gerdes AM; Department of Clinical Genetics, Rigshospitalet, Copenhagen University Hospital, DK-2100 Copenhagen, Denmark., Ghoussaini M; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge CB1 8RN, UK., Giles GG; Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Victoria 3010, Australia., Glendon G; Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada M5G 1X5., Godwin AK; Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, Kansas, 66205, USA., Goldberg MS; Department of Medicine, McGill University, Montreal, Quebec, Canada H3G 2M1.; Division of Clinical Epidemiology, McGill University Health Centre, Royal Victoria Hospital, Montreal, Quebec, Canada H4A 3J1., Goldgar DE; Department of Dermatology, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, Utah 84132, USA., González-Neira A; Human Genotyping-CEGEN Unit, Human Cancer Genetics Program, Spanish National Cancer Research Centre (CNIO), 28029 Madrid, Spain., Greene MH; Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, Maryland 20850-9772, USA., Gronwald J; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland., Guénel P; Inserm (National Institute of Health and Medical Research), CESP (Center for Research in Epidemiology and Population Health), U1018, Environmental Epidemiology of Cancer, 70-115 Villejuif, France., Gunter M; Department of of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, SW7 2AZ, UK., Haeberle L; University Breast Center Franconia, Department of Gynecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, 91054 Erlangen, Germany., Haiman CA; Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California 90033, USA., Hamann U; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany., Hansen TV; Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital, DK-2100 Copenhagen, Denmark., Hart S; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, USA., Healey S; Department of Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Queensland 4029, Australia., Heikkinen T; Department of Obstetrics and Gynecology, University of Heidelberg, 69120 Heidelberg, Germany.; Helsinki University Central Hospital, FI-00029 Helsinki, Finland., Henderson BE; Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California 90033, USA., Herzog J; Clinical Cancer Genetics, for the City of Hope Clinical Cancer Genetics Community Research Network, Duarte, California 91010, USA., Hogervorst FB; Family Cancer Clinic, Netherlands Cancer Institute, Amsterdam 1000 BE, The Netherlands., Hollestelle A; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam 3008 AE, The Netherlands., Hooning MJ; Department of Medical Oncology, Family Cancer Clinic, Erasmus University Medical Center, Rotterdam 3008 AE, The Netherlands., Hoover RN; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland 20850, USA., Hopper JL; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria 3010, Australia., Humphreys K; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, SE-17177 Stockholm, Sweden., Hunter DJ; Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA., Huzarski T; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland., Imyanitov EN; N.N. Petrov Institute of Oncology, 197758 St Petersburg, Russia., Isaacs C; Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20007, USA., Jakubowska A; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland., James P; Familial Cancer Centre, Peter MacCallum Cancer Centre, Melbourne, Victoria 8006, Australia.; Department of Oncology, The University of Melbourne, Melbourne, Victoria 8006, Australia., Janavicius R; State Research Institute Centre for Innovative Medicine, LT-08661 Vilnius, Lithuania., Jensen UB; Department of Clinical Genetics, Aarhus University Hospital, 8200 Aarhus N, Denmark., John EM; Department of Epidemiology, Cancer Prevention Institute of California, Fremont, California 94538, USA., Jones M; Division of Genetics and Epidemiology, Institute of Cancer Research, Sutton SM2 5NG, UK., Kabisch M; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany., Kar S; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge CB1 8RN, UK., Karlan BY; Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California, 90048, USA., Khan S; Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, FI-00029 Helsinki, Finland., Khaw KT; Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Cambridge CB1 8RN, UK., Kibriya MG; Department of Health Studies, The University of Chicago, Chicago, Illinois 60637, USA., Knight JA; Prosserman Centre for Health Research, Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada M5G 1X5., Ko YD; Department of Internal Medicine, Evangelische Kliniken Bonn gGmbH, Johanniter Krankenhaus, 53113 Bonn, Germany., Konstantopoulou I; Molecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research 'Demokritos', Aghia Paraskevi Attikis, 15310 Athens, Greece., Kosma VM; School of Medicine, Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, FI-70211 Kuopio, Finland., Kristensen V; Department of Genetics, Institute for Cancer Research, Oslo University Hospital, Radiumhospitalet, N-0310 Oslo, Norway., Kwong A; The Hong Kong Hereditary Breast Cancer Family Registry, Cancer Genetics Center, Hong Kong Sanatorium and Hospital, Hong Kong.; Department of Surgery, The University of Hong Kong, Hong Kong, China., Laitman Y; Susanne Levy Gertner Oncogenetics Unit, Sheba Medical Center, Tel-Hashomer 52621, Israel., Lambrechts D; Vesalius Research Center, VIB, 3000 Leuven, Belgium., Lazaro C; Molecular Diagnostic Unit, Hereditary Cancer Program, IDIBELL-Catalan Institute of Oncology, 08908 Barcelona, Spain., Lee E; Department of Preventive Medicine, University of Southern California, Los Angeles, California 90032, USA., Le Marchand L; Cancer Epidemiology Program, University of Cancer Center, Honolulu, Hawaii 96813, USA., Lester J; Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California, 90048, USA., Lindblom A; Department of Molecular Medicine and Surgery, Karolinska Institutet, SE-17177 Stockholm, Sweden., Lindor N; Health Sciences Research, Mayo Clinic, Scotsdale, Arizona 85259, USA., Lindstrom S; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA.; Program in Genetic Epidemiology and Statistical Genetics, Harvard School of Public Health, Boston, Massachusetts 02115, USA., Liu J; Human Genetics Division, Genome Institute of Singapore, Singapore 138672, Singapore., Long J; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center and Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37203, USA., Lubinski J; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland., Mai PL; Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, Maryland 20850-9772, USA., Makalic E; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria 3010, Australia., Malone KE; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.; Department of Epidemiology, School of Public Health and Community Medicine, University of Washington, Seattle, Washington 98195, USA., Mannermaa A; School of Medicine, Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, FI-70211 Kuopio, Finland., Manoukian S; Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), 20133 Milan, Italy., Margolin S; Department of Oncology, Karolinska University Hospital, SE-17176 Stockholm, Sweden., Marme F; Department of Obstetrics and Gynecology, University of Heidelberg, 69120 Heidelberg, Germany., Martens JW; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam 3008 AE, The Netherlands., McGuffog L; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK., Meindl A; Department of Gynaecology and Obstetrics, Technical University of Munich, 81675 Munich, Germany., Miller A; NRG Oncology Statistics and Data Management Center, Roswell Park Cancer Institute, Buffalo, New York 14263, USA., Milne RL; Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Victoria 3010, Australia., Miron P; Department of Genomics and Genome Sciences, Case Western Reserve University Medical School, Cleveland, Ohio 44106, USA., Montagna M; Immunology and Molecular Oncology Unit, Istituto Oncologico Veneto IOV-IRCCS, 20133 Padua, Italy., Mazoyer S; INSERM U1052, CNRS UMR5286, Université Lyon, Centre de Recherche en Cancérologie de Lyon, 69373 Lyon, France., Mulligan AM; Laboratory Medicine Program, University Health Network, Toronto, Ontario, Canada M5B 1W8.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada M5B 1W8., Muranen TA; Department of Obstetrics and Gynecology, University of Heidelberg, 69120 Heidelberg, Germany.; Helsinki University Central Hospital, FI-00029 Helsinki, Finland., Nathanson KL; Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Pennsylvania 19104, USA., Neuhausen SL; Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, California 91010, USA., Nevanlinna H; Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, FI-00029 Helsinki, Finland., Nordestgaard BG; Copenhagen General Population Study, Herlev Hospital, Copenhagen University Hospital, 2730 Herlev, Denmark., Nussbaum RL; Invitae Corporation, San Francisco, California 94107, USA., Offit K; Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA., Olah E; Department of Molecular Genetics, National Institute of Oncology, H-1122 Budapest, Hungary., Olopade OI; Center for Clinical Cancer Genetics and Global Health, University of Chicago Medical Center, Chicago, Illinois 60637, USA., Olson JE; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, USA., Osorio A; Human Genetics Group, Human Cancer Genetics Program, Spanish National Cancer Centre (CNIO), 28029 Madrid, Spain., Park SK; Department of Preventive Medicine and Biomedical Science, Seoul National University College of Medicine and Cancer Research Institute, Seoul National University, 110-799 Seoul, Republic of Korea., Peeters PH; Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center, Utrecht 3508 GA, The Netherlands.; MRC-PHE Centre for Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London SW7 2AZ, UK., Peissel B; Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), 20133 Milan, Italy., Peterlongo P; IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, 20133 Milan, Italy., Peto J; Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, WC1E 7HT, UK., Phelan CM; Cancer Epidemiology Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida 33612, USA., Pilarski R; Divison of Human Genetics, Department of Internal Medicine, The Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio 43210, USA., Poppe B; Center for Medical Genetics, Ghent University, 9000 Ghent, Belgium., Pylkäs K; Laboratory of Cancer Genetics and Tumor Biology, Department of Clinical Chemistry and Biocenter Oulu, University of Oulu, NordLab Oulu/Oulu University Hospital, FI-90220 Oulu, Finland., Radice P; Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), 20133 Milan, Italy., Rahman N; Section of Cancer Genetics, Institute of Cancer Research, Sutton SM2 5NG, UK., Rantala J; Department of Clinical Genetics, Karolinska University Hospital, SE-17176 Stockholm, Sweden., Rappaport C; Department of Obstetrics and Gynecology, Comprehensive Cancer Center, Medical University of Vienna, A 1090 Vienna, Austria., Rennert G; Clalit National Israeli Cancer Control Center and Department of Community Medicine and Epidemiology, Carmel Medical Center and B. Rappaport Faculty of Medicine, Haifa 34362, Israel., Richardson A; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, 21205, USA., Robson M; Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA., Romieu I; International Agency for Research on Cancer, 69008 Lyon, France., Rudolph A; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany., Rutgers EJ; Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam 1006 BE, The Netherlands., Sanchez MJ; Escuela Andaluza de Salud Pública. Instituto de Investigación Biosanitaria ibs.GRANADA, Hospitales Universitarios de Granada/Universidad de Granada, 18014 Granada, Spain.; CIBER de Epidemiología y Salud Pública (CIBERESP), Spain., Santella RM; Department of Environmental Health Sciences, Columbia University, New York, New York, 10032, USA., Sawyer EJ; Research Oncology, Division of Cancer Studies, King's College London, Guy's Hospital, London SE1 9RT, UK., Schmidt DF; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria 3010, Australia., Schmidt MK; Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam 1006 BE, The Netherlands., Schmutzler RK; Center for Hereditary Breast and Ovarian Cancer, Medical Faculty, University Hospital Cologne, Cologne 50931, Germany.; Center for Integrated Oncology (CIO), Medical Faculty, University Hospital Cologne, 50931 Cologne, Germany.; Center for Molecular Medicine Cologne (CMMC), University of Cologne, 50931 Cologne, Germany., Schumacher F; Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California 90033, USA., Scott R; Division of Genetics, Hunter Area Pathology Service, John Hunter Hospital, Newcastle, New South Wales 2305, Australia., Senter L; Divison of Human Genetics, Department of Internal Medicine, The Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio 43210, USA., Sharma P; Department of Hematology and Oncology, University of Kansas Medical Center, Kansas City, Kansas 66205, USA., Simard J; Centre Hospitalier Universitaire de Québec Research Center, Laval University, Quebec City, Quebec, Canada G1V 4G2., Singer CF; Department of Obstetrics and Gynecology, Comprehensive Cancer Center, Medical University of Vienna, A 1090 Vienna, Austria., Sinilnikova OM; INSERM U1052, CNRS UMR5286, Université Lyon, Centre de Recherche en Cancérologie de Lyon, 69373 Lyon, France.; Unité Mixte de Génétique Constitutionnelle des Cancers Fréquents, Hospices Civils de Lyon-Centre Léon Bérard, 69373 Lyon, France., Soucy P; 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المصدر: Nature communications [Nat Commun] 2016 Apr 27; Vol. 7, pp. 11375. Date of Electronic Publication: 2016 Apr 27.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Breast Neoplasms/*genetics , Genetic Predisposition to Disease/*genetics , Genome-Wide Association Study/*methods , Receptors, Estrogen/*genetics, BRCA1 Protein/genetics ; Chromosomes, Human, Pair 2/genetics ; Cyclophilins/genetics ; Female ; Genotype ; Heterozygote ; Humans ; Mutation ; Polymorphism, Single Nucleotide ; Risk Factors ; tRNA Methyltransferases

المؤلفون: Kuchenbaecker KB; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Ramus SJ; Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California, USA., Tyrer J; Department of Oncology, University of Cambridge, Strangeways Research Laboratory, Cambridge, UK., Lee A; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Shen HC; Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California, USA., Beesley J; Cancer Division, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Lawrenson K; Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California, USA., McGuffog L; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Healey S; Cancer Division, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Lee JM; Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California, USA., Spindler TJ; Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California, USA., Lin YG; Department of Obstetrics and Gynecology, University of Southern California, Los Angeles, California, USA., Pejovic T; 1] Department of Obstetrics and Gynecology, Oregon Health and Science University, Portland, Oregon, USA. [2] Knight Cancer Institute, Portland, Oregon, USA., Bean Y; 1] Department of Obstetrics and Gynecology, Oregon Health and Science University, Portland, Oregon, USA. [2] Knight Cancer Institute, Portland, Oregon, USA., Li Q; Department of Medical Oncology, Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, Massachusetts, USA., Coetzee S; 1] Department of Genetics, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil. [2] Center for Cell-Based Therapy, Monte Alegre, Ribeirão Preto, Brazil. [3] Center for Integrative Systems Biology, Monte Alegre, Ribeirão Preto, Brazil., Hazelett D; 1] Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California, USA. 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[2] Community and Population Health Research Institute, Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California, USA., Shvetsov YB; Cancer Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii, USA., Runnebaum IB; Department of Gynecology, Jena University Hospital-Friedrich Schiller University, Jena, Germany., Dürst M; Department of Gynecology, Jena University Hospital-Friedrich Schiller University, Jena, Germany., Hillemanns P; Clinics of Obstetrics and Gynaecology, Hannover Medical School, Hannover, Germany., Dörk T; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany., Antonenkova N; Byelorussian Institute for Oncology and Medical Radiology Aleksandrov N.N., Minsk, Belarus., Bogdanova N; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany., Leminen A; Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland., Pelttari LM; Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland., Butzow R; 1] Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland. [2] Department of Pathology, Helsinki University Central Hospital, Helsinki, Finland., Modugno F; 1] Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA. [2] Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA. [3] Ovarian Cancer Center of Excellence, University of Pittsburgh, Pittsburgh, Pennsylvania, USA. [4] Women's Cancer Research Program, Magee-Women's Research Institute and University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, USA., Kelley JL; Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Edwards RP; 1] Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA. [2] Ovarian Cancer Center of Excellence, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Ness RB; University of Texas School of Public Health, Houston, Texas, USA., du Bois A; 1] Department of Gynecology and Gynecologic Oncology, Dr. Horst Schmidt Kliniken Wiesbaden, Wiesbaden, Germany. [2] Department of Gynecology and Gynecologic Oncology, Kliniken Essen-Mitte, Essen, Germany., Heitz F; 1] Department of Gynecology and Gynecologic Oncology, Dr. Horst Schmidt Kliniken Wiesbaden, Wiesbaden, Germany. [2] Department of Gynecology and Gynecologic Oncology, Kliniken Essen-Mitte, Essen, Germany., Schwaab I; Institut für Humangenetik Wiesbaden, Wiesbaden, Germany., Harter P; 1] Department of Gynecology and Gynecologic Oncology, Dr. Horst Schmidt Kliniken Wiesbaden, Wiesbaden, Germany. [2] Department of Gynecology and Gynecologic Oncology, Kliniken Essen-Mitte, Essen, Germany., Matsuo K; Department of Preventive Medicine, Kyushu University Faculty of Medical Sciences, Fukuoka, Japan., Hosono S; Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan., Orsulic S; Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA., Jensen A; Department of Virus, Lifestyle and Genes, Danish Cancer Society Research Center, Copenhagen, Denmark., Kjaer SK; 1] Department of Virus, Lifestyle and Genes, Danish Cancer Society Research Center, Copenhagen, Denmark. [2] Department of Gynecology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark., Hogdall E; 1] Department of Virus, Lifestyle and Genes, Danish Cancer Society Research Center, Copenhagen, Denmark. [2] Molecular Unit, Department of Pathology, Herlev Hospital, University of Copenhagen, Copenhagen, Denmark., Hasmad HN; Cancer Research Initiatives Foundation, Sime Darby Medical Centre, Subang Jaya, Malaysia., Azmi MA; Department of Obstetrics and Gynaecology, University Malaya Medical Centre, University Malaya, Kuala Lumpur, Malaysia., Teo SH; 1] Cancer Research Initiatives Foundation, Sime Darby Medical Centre, Subang Jaya, Malaysia. [2] University Malaya Cancer Research Institute, Faculty of Medicine, University Malaya Medical Centre, University Malaya, Kuala Lumpur, Malaysia., Woo YL; 1] Department of Obstetrics and Gynaecology, University Malaya Medical Centre, University Malaya, Kuala Lumpur, Malaysia. [2] University Malaya Cancer Research Institute, Faculty of Medicine, University Malaya Medical Centre, University Malaya, Kuala Lumpur, Malaysia., Fridley BL; Biostatistics and Informatics Shared Resource, University of Kansas Medical Center, Kansas City, Kansas, USA., Goode EL; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA., Cunningham JM; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA., Vierkant RA; Department of Health Science Research, Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, Minnesota, USA., Bruinsma F; Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Victoria, Australia., Giles GG; Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Victoria, Australia., Liang D; College of Pharmacy and Health Sciences, Texas Southern University, Houston, Texas, USA., Hildebrandt MA; Department of Epidemiology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Wu X; Department of Epidemiology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Levine DA; Gynecology Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York, USA., Bisogna M; Gynecology Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York, USA., Berchuck A; Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, North Carolina, USA., Iversen ES; Department of Statistical Science, Duke University, Durham, North Carolina, USA., Schildkraut JM; 1] Cancer Control and Population Sciences, Duke Cancer Institute, Durham, North Carolina, USA. [2] Department of Community and Family Medicine, Duke University Medical Center, Durham, North Carolina, USA., Concannon P; 1] Department of Pathology, Immunology and Laboratory Medicine, University of Florida, Gainesville, Florida, USA. [2] Genetics Institute, University of Florida, Gainesville, Florida, USA., Weber RP; Department of Community and Family Medicine, Duke University Medical Center, Durham, North Carolina, USA., Cramer DW; 1] Harvard School of Public Health, Boston, Massachusetts, USA. [2] Obstetrics and Gynecology Epidemiology Center, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA., Terry KL; 1] Harvard School of Public Health, Boston, Massachusetts, USA. [2] Obstetrics and Gynecology Epidemiology Center, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA., Poole EM; 1] Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA. [2] Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA., Tworoger SS; 1] Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA. [2] Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA., Bandera EV; Cancer Prevention and Control, Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey, USA., Orlow I; Department of Epidemiology and Biostatistics, Epidemiology Service, Memorial Sloan-Kettering Cancer Center, New York, New York, USA., Olson SH; Department of Epidemiology and Biostatistics, Epidemiology Service, Memorial Sloan-Kettering Cancer Center, New York, New York, USA., Krakstad C; 1] Centre for Cancer Biomarkers, Department of Clinical Medicine, University of Bergen, Bergen, Norway. [2] Department of Gynecology and Obstetrics, Haukeland University Hospital, Bergen, Norway., Salvesen HB; 1] Centre for Cancer Biomarkers, Department of Clinical Medicine, University of Bergen, Bergen, Norway. [2] Department of Gynecology and Obstetrics, Haukeland University Hospital, Bergen, Norway., Tangen IL; 1] Centre for Cancer Biomarkers, Department of Clinical Medicine, University of Bergen, Bergen, Norway. [2] Department of Gynecology and Obstetrics, Haukeland University Hospital, Bergen, Norway., Bjorge L; 1] Centre for Cancer Biomarkers, Department of Clinical Medicine, University of Bergen, Bergen, Norway. [2] Department of Gynecology and Obstetrics, Haukeland University Hospital, Bergen, Norway., van Altena AM; Department of Gynaecology, Radboud University Medical Centre, Nijmegen, the Netherlands., Aben KK; 1] Comprehensive Cancer Center The Netherlands, Utrecht, the Netherlands. [2] Department for Health Evidence, Radboud University Medical Centre, Nijmegen, the Netherlands., Kiemeney LA; 1] Department for Health Evidence, Radboud University Medical Centre, Nijmegen, the Netherlands. [2] Department of Urology, Radboud University Medical Centre, Nijmegen, the Netherlands., Massuger LF; Department of Gynaecology, Radboud University Medical Centre, Nijmegen, the Netherlands., Kellar M; 1] Department of Obstetrics and Gynecology, Oregon Health and Science University, Portland, Oregon, USA. [2] Knight Cancer Institute, Portland, Oregon, USA., Brooks-Wilson A; 1] Canada's Michael Smith Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, British Columbia, Canada. [2] Department of Biomedical Physiology and Kinesiology, Simon Fraser University, Burnaby, British Columbia, Canada., Kelemen LE; Department of Public Health Sciences, College of Medicine, Medical University of South Carolina, Charleston, South Carolina, USA., Cook LS; Division of Epidemiology and Biostatistics, Department of Internal Medicine, University of New Mexico, Albuquerque, New Mexico, USA., Le ND; Cancer Control Research, British Columbia Cancer Agency, Vancouver, British Columbia, Canada., Cybulski C; International Hereditary Cancer Center, Department of Genetics and Pathology, Clinic of Opthalmology, Pomeranian Medical University, Szczecin, Poland., Yang H; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA., Lissowska J; Department of Cancer Epidemiology and Prevention, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland., Brinton LA; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA., Wentzensen N; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA., Hogdall C; Department of Gynecology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark., Lundvall L; Department of Gynecology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark., Nedergaard L; Department of Pathology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark., Baker H; Department of Oncology, University of Cambridge, Strangeways Research Laboratory, Cambridge, UK., Song H; Department of Oncology, University of Cambridge, Strangeways Research Laboratory, Cambridge, UK., Eccles D; Wessex Clinical Genetics Service, Princess Anne Hospital, Southampton, UK., McNeish I; Institute of Cancer Sciences, University of Glasgow, Wolfson Wohl Cancer Research Centre, Beatson Institute for Cancer Research, Glasgow, UK., Paul J; Cancer Research UK Clinical Trials Unit, Glasgow, Beatson West of Scotland Cancer Centre, Glasgow, UK., Carty K; Cancer Research UK Clinical Trials Unit, Glasgow, Beatson West of Scotland Cancer Centre, Glasgow, UK., Siddiqui N; Department of Gynaecological Oncology, Glasgow Royal Infirmary, Glasgow, UK., Glasspool R; Cancer Research UK Clinical Trials Unit, Glasgow, Beatson West of Scotland Cancer Centre, Glasgow, UK., Whittemore AS; Department of Health Research and Policy-Epidemiology, Stanford University School of Medicine, Stanford, California, USA., Rothstein JH; Department of Health Research and Policy-Epidemiology, Stanford University School of Medicine, Stanford, California, USA., McGuire V; Department of Health Research and Policy-Epidemiology, Stanford University School of Medicine, Stanford, California, USA., Sieh W; Department of Health Research and Policy-Epidemiology, Stanford University School of Medicine, Stanford, California, USA., Ji BT; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA., Zheng W; Vanderbilt University School of Medicine, Nashville, Tennessee, USA., Shu XO; Vanderbilt University School of Medicine, Nashville, Tennessee, USA., Gao YT; Shanghai Cancer Institute, Shanghai, China., Rosen B; 1] Department of Obstetrics and Gynecology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada. [2] Department of Gynecologic-Oncology, Princess Margaret Hospital, Toronto, Ontario, Canada., Risch HA; Department of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, Connecticut, USA., McLaughlin JR; Prosserman Centre for Health Research, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada., Narod SA; Women's College Research Institute, University of Toronto, Toronto, Ontario, Canada., Monteiro AN; Department of Cancer Epidemiology, Moffitt Cancer Center, Tampa, Florida, USA., Chen A; Department of Biostatistics, Moffitt Cancer Center, Tampa, Florida, USA., Lin HY; Department of Biostatistics, Moffitt Cancer Center, Tampa, Florida, USA., Permuth-Wey J; Department of Cancer Epidemiology, Moffitt Cancer Center, Tampa, Florida, USA., Sellers TA; Department of Cancer Epidemiology, Moffitt Cancer Center, Tampa, Florida, USA., Tsai YY; Department of Cancer Epidemiology, Moffitt Cancer Center, Tampa, Florida, USA., Chen Z; Department of Biostatistics, Moffitt Cancer Center, Tampa, Florida, USA., Ziogas A; Department of Epidemiology, University of California-Irvine, Irvine, California, USA., Anton-Culver H; Department of Epidemiology, University of California-Irvine, Irvine, California, USA., Gentry-Maharaj A; Women's Cancer, University College London Elizabeth Garrett Anderson (EGA) Institute for Women's Health, London, UK., Menon U; Women's Cancer, University College London Elizabeth Garrett Anderson (EGA) Institute for Women's Health, London, UK., Harrington P; Department of Oncology, University of Cambridge, Strangeways Research Laboratory, Cambridge, UK., Lee AW; Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California, USA., Wu AH; Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California, USA., Pearce CL; Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California, USA., Coetzee G; 1] Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California, USA. [2] Department of Urology, University of Southern California, Los Angeles, California, USA., Pike MC; 1] Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California, USA. [2] Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, New York, USA., Dansonka-Mieszkowska A; Department of Pathology, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland., Timorek A; Department of Obstetrics, Gynecology and Oncology, 2nd Faculty of Medicine, Warsaw Medical University and Brodnowski Hospital, Warsaw, Poland., Rzepecka IK; Department of Pathology, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland., Kupryjanczyk J; Department of Pathology, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland., Freedman M; Department of Medical Oncology, Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, Massachusetts, USA., Noushmehr H; Department of Genetics, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil., Easton DF; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Offit K; Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York, USA., Couch FJ; 1] Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA. [2] Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA., Gayther S; Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California, USA., Pharoah PP; Department of Oncology, University of Cambridge, Strangeways Research Laboratory, Cambridge, UK., Antoniou AC; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Chenevix-Trench G; Cancer Division, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.

مؤلفون مشاركون: EMBRACE, GEMO Study Collaborators, Breast Cancer Family Registry, HEBON, KConFab Investigators, Australian Cancer Study (Ovarian Cancer Investigators), Australian Ovarian Cancer Study Group, Consortium of Investigators of Modifiers of BRCA1 and BRCA2

المصدر: Nature genetics [Nat Genet] 2015 Feb; Vol. 47 (2), pp. 164-71. Date of Electronic Publication: 2015 Jan 12.

نوع المنشور: Journal Article; Meta-Analysis; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE

مواضيع طبية MeSH: Genetic Predisposition to Disease* , Polymorphism, Single Nucleotide*, BRCA1 Protein/*genetics , BRCA2 Protein/*genetics , Genome-Wide Association Study/*methods , Neoplasms, Glandular and Epithelial/*genetics , Ovarian Neoplasms/*genetics, Adolescent ; Adult ; Alleles ; Carcinoma, Ovarian Epithelial ; Female ; Genes, Reporter ; Genotype ; Heterozygote ; Humans ; Mutation ; Quantitative Trait Loci ; Risk ; Young Adult

المؤلفون: Couch FJ; Department of Laboratory Medicine and Pathology, and Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA., Wang X, McGuffog L, Lee A, Olswold C, Kuchenbaecker KB, Soucy P, Fredericksen Z, Barrowdale D, Dennis J, Gaudet MM, Dicks E, Kosel M, Healey S, Sinilnikova OM, Lee A, Bacot F, Vincent D, Hogervorst FB, Peock S, Stoppa-Lyonnet D, Jakubowska A, Radice P, Schmutzler RK, Domchek SM, Piedmonte M, Singer CF, Friedman E, Thomassen M, Hansen TV, Neuhausen SL, Szabo CI, Blanco I, Greene MH, Karlan BY, Garber J, Phelan CM, Weitzel JN, Montagna M, Olah E, Andrulis IL, Godwin AK, Yannoukakos D, Goldgar DE, Caldes T, Nevanlinna H, Osorio A, Terry MB, Daly MB, van Rensburg EJ, Hamann U, Ramus SJ, Toland AE, Caligo MA, Olopade OI, Tung N, Claes K, Beattie MS, Southey MC, Imyanitov EN, Tischkowitz M, Janavicius R, John EM, Kwong A, Diez O, Balmaña J, Barkardottir RB, Arun BK, Rennert G, Teo SH, Ganz PA, Campbell I, van der Hout AH, van Deurzen CH, Seynaeve C, Gómez Garcia EB, van Leeuwen FE, Meijers-Heijboer HE, Gille JJ, Ausems MG, Blok MJ, Ligtenberg MJ, Rookus MA, Devilee P, Verhoef S, van Os TA, Wijnen JT, Frost D, Ellis S, Fineberg E, Platte R, Evans DG, Izatt L, Eeles RA, Adlard J, Eccles DM, Cook J, Brewer C, Douglas F, Hodgson S, Morrison PJ, Side LE, Donaldson A, Houghton C, Rogers MT, Dorkins H, Eason J, Gregory H, McCann E, Murray A, Calender A, Hardouin A, Berthet P, Delnatte C, Nogues C, Lasset C, Houdayer C, Leroux D, Rouleau E, Prieur F, Damiola F, Sobol H, Coupier I, Venat-Bouvet L, Castera L, Gauthier-Villars M, Léoné M, Pujol P, Mazoyer S, Bignon YJ, Złowocka-Perłowska E, Gronwald J, Lubinski J, Durda K, Jaworska K, Huzarski T, Spurdle AB, Viel A, Peissel B, Bonanni B, Melloni G, Ottini L, Papi L, Varesco L, Tibiletti MG, Peterlongo P, Volorio S, Manoukian S, Pensotti V, Arnold N, Engel C, Deissler H, Gadzicki D, Gehrig A, Kast K, Rhiem K, Meindl A, Niederacher D, Ditsch N, Plendl H, Preisler-Adams S, Engert S, Sutter C, Varon-Mateeva R, Wappenschmidt B, Weber BH, Arver B, Stenmark-Askmalm M, Loman N, Rosenquist R, Einbeigi Z, Nathanson KL, Rebbeck TR, Blank SV, Cohn DE, Rodriguez GC, Small L, Friedlander M, Bae-Jump VL, Fink-Retter A, Rappaport C, Gschwantler-Kaulich D, Pfeiler G, Tea MK, Lindor NM, Kaufman B, Shimon Paluch S, Laitman Y, Skytte AB, Gerdes AM, Pedersen IS, Moeller ST, Kruse TA, Jensen UB, Vijai J, Sarrel K, Robson M, Kauff N, Mulligan AM, Glendon G, Ozcelik H, Ejlertsen B, Nielsen FC, Jønson L, Andersen MK, Ding YC, Steele L, Foretova L, Teulé A, Lazaro C, Brunet J, Pujana MA, Mai PL, Loud JT, Walsh C, Lester J, Orsulic S, Narod SA, Herzog J, Sand SR, Tognazzo S, Agata S, Vaszko T, Weaver J, Stavropoulou AV, Buys SS, Romero A, de la Hoya M, Aittomäki K, Muranen TA, Duran M, Chung WK, Lasa A, Dorfling CM, Miron A, Benitez J, Senter L, Huo D, Chan SB, Sokolenko AP, Chiquette J, Tihomirova L, Friebel TM, Agnarsson BA, Lu KH, Lejbkowicz F, James PA, Hall P, Dunning AM, Tessier D, Cunningham J, Slager SL, Wang C, Hart S, Stevens K, Simard J, Pastinen T, Pankratz VS, Offit K, Easton DF, Chenevix-Trench G, Antoniou AC

مؤلفون مشاركون: kConFab Investigators, SWE-BRCA, Ontario Cancer Genetics Network, HEBON, EMBRACE, GEMO Study Collaborators, BCFR, CIMBA

المصدر: PLoS genetics [PLoS Genet] 2013; Vol. 9 (3), pp. e1003212. Date of Electronic Publication: 2013 Mar 27.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1553-7404 (Electronic) Linking ISSN: 15537390 NLM ISO Abbreviation: PLoS Genet Subsets: MEDLINE

مواضيع طبية MeSH: Genome-Wide Association Study*, BRCA1 Protein/*genetics , Breast Neoplasms/*genetics , Ovarian Neoplasms/*genetics, BRCA2 Protein/genetics ; Breast Neoplasms/pathology ; Female ; Genetic Predisposition to Disease ; Genotype ; Heterozygote ; Humans ; Middle Aged ; Mutation ; Ovarian Neoplasms/pathology ; Polymorphism, Single Nucleotide ; Prognosis ; Risk Factors

المؤلفون: Gaudet MM; Department of Epidemiology and Population Health and Department of Obstetrics and Gynecology and Women's Health, Albert Einstein College of Medicine, New York, New York, United States of America., Kirchhoff T, Green T, Vijai J, Korn JM, Guiducci C, Segrè AV, McGee K, McGuffog L, Kartsonaki C, Morrison J, Healey S, Sinilnikova OM, Stoppa-Lyonnet D, Mazoyer S, Gauthier-Villars M, Sobol H, Longy M, Frenay M, GEMO Study Collaborators, Hogervorst FB, Rookus MA, Collée JM, Hoogerbrugge N, van Roozendaal KE, Piedmonte M, Rubinstein W, Nerenstone S, Van Le L, Blank SV, Caldés T, de la Hoya M, Nevanlinna H, Aittomäki K, Lazaro C, Blanco I, Arason A, Johannsson OT, Barkardottir RB, Devilee P, Olopade OI, Neuhausen SL, Wang X, Fredericksen ZS, Peterlongo P, Manoukian S, Barile M, Viel A, Radice P, Phelan CM, Narod S, Rennert G, Lejbkowicz F, Flugelman A, Andrulis IL, Glendon G, Ozcelik H, Toland AE, Montagna M, D'Andrea E, Friedman E, Laitman Y, Borg A, Beattie M, Ramus SJ, Domchek SM, Nathanson KL, Rebbeck T, Spurdle AB, Chen X, Holland H, John EM, Hopper JL, Buys SS, Daly MB, Southey MC, Terry MB, Tung N, Overeem Hansen TV, Nielsen FC, Greene MH, Mai PL, Osorio A, Durán M, Andres R, Benítez J, Weitzel JN, Garber J, Hamann U, Peock S, Cook M, Oliver C, Frost D, Platte R, Evans DG, Lalloo F, Eeles R, Izatt L, Walker L, Eason J, Barwell J, Godwin AK, Schmutzler RK, Wappenschmidt B, Engert S, Arnold N, Gadzicki D, Dean M, Gold B, Klein RJ, Couch FJ, Chenevix-Trench G, Easton DF, Daly MJ, Antoniou AC, Altshuler DM, Offit K

مؤلفون مشاركون: HEBON Study Collaborators, OCGN, kConFab, EMBRACE

المصدر: PLoS genetics [PLoS Genet] 2010 Oct 28; Vol. 6 (10), pp. e1001183. Date of Electronic Publication: 2010 Oct 28.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: Electronic Cited Medium: Internet ISSN: 1553-7404 (Electronic) Linking ISSN: 15537390 NLM ISO Abbreviation: PLoS Genet Subsets: MEDLINE

مواضيع طبية MeSH: Polymorphism, Single Nucleotide*, BRCA2 Protein/*genetics , Breast Neoplasms/*genetics , Genome-Wide Association Study/*methods, Adult ; Chromosomes, Human, Pair 10 ; Chromosomes, Human, Pair 20 ; DNA-Binding Proteins/genetics ; Female ; Gene Frequency ; Genetic Predisposition to Disease/genetics ; Haplotypes ; Heterozygote ; Humans ; Linkage Disequilibrium ; Middle Aged ; Mutation ; Penetrance ; Receptor, Fibroblast Growth Factor, Type 2/genetics ; Risk Factors ; Transcription Factors/genetics ; White People/genetics