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1دورية أكاديمية
المؤلفون: Анастасия Владимировна Миронова, Юлия Олеговна Рождественская, Ирина Владимировна Болгова, Яна Вячеславовна Юнкина, Светлана Ивановна Елгина, Елена Владимировна Рудаева, Кира Борисовна Мозес, Яэль Центер, Наталья Степановна Черных
المصدر: Мать и дитя в Кузбассе, Vol 25, Iss 1, Pp 105-108 (2024)
مصطلحات موضوعية: тромбоцитопения, диагностика, лечение, прогноз, Pediatrics, RJ1-570, Gynecology and obstetrics, RG1-991
الوصف: Thrombocytopenia is a pathological condition characterized by a decrease in the number of platelets below 100 × 109/l. There are primary and secondary thrombocytopenia. However, the severity of thrombocytopenia is determined not by the number of platelets, but by the severity of hemorrhagic syndrome, which is manifested by the occurrence of petechiae, ecchymoses and bleeding from the microcirculatory bed. The article presents a retrospective analysis of the case histories of 128 patients with thrombocytopenia who were treated at the Kuzbass Clinical Hospital named after S.V. Belyaev for 9 years. With dynamic monitoring, timely medical care and adequate therapy, the prognosis for the life and health of patients with ITP is favorable.
وصف الملف: electronic resource
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2دورية أكاديمية
المؤلفون: Елена Николаевна Кравченко, Татьяна Николаевна Кудымова, Екатерина Владимировна Лисица, Инга Олеговна Ульянова
المصدر: Мать и дитя в Кузбассе, Vol 25, Iss 1, Pp 73-81 (2024)
مصطلحات موضوعية: интерферон-альфа 2b, лечение вирусных инфекций в гинекологии, профилактика осложнений и реабилитация, Pediatrics, RJ1-570, Gynecology and obstetrics, RG1-991
الوصف: The literature review presents data on the use of the drug Interferon-α2b in the treatment of viral and co-infections. The data presented show the benefit of immunostimulating drugs used to treat infections caused by viral etiology. The presented material indicates the high clinical effectiveness and safety of the drug containing Interferon-α2b with antioxidants for infections caused by the herpes simplex virus, human papillomavirus, cervicitis, anogenital warts and other diseases. It is reflected that the drug containing Interferon-α2b can be used in combination with other treatment methods: conservative, surgical and physiotherapeutic. The drug Interferon-α2b with antioxidants is used in adolescent and pediatric gynecology, in obstetric practice to prevent perinatal complications.
وصف الملف: electronic resource
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3دورية أكاديمية
المصدر: Мать и дитя в Кузбассе, Vol 24, Iss 2, Pp 71-77 (2023)
مصطلحات موضوعية: хронический аденоидит, дети, гипертрофия аденоидов, лечение аденоидита, ступенчатая терапия, Pediatrics, RJ1-570, Gynecology and obstetrics, RG1-991
الوصف: The article provides a review of the literature, considered the heterogeneity of chronic adenoiditis and approaches to treatment based on the allocation of clinical manifestations of various phenotypes, biological and genetic markers and endotypes, taking into account the etiology and pathophysiology of the disease. Selection of phenotypes and endotypes contributes to a better understanding of the essence of the disease and is advisable for developing an individual approach to therapy, since some variants of chronic adenoiditis and pharyngeal tonsil hypertrophy may be characterized by resistance to standard therapy. The article formulates theoretical prerequisites for changing the paradigm of treatment of chronic adenoiditis from anti-infective and/or anti-allergic to step therapy, depending on the response to the initial treatment.
وصف الملف: electronic resource
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4دورية أكاديمية
المؤلفون: Татьяна Николаевна Елкина, Ольга Александровна Грибанова, Наталья Игоревна Пирожкова, Маргарита Геннадьевна Лиханова, Анастасия Сергеевна Кузнецова
المصدر: Мать и дитя в Кузбассе, Vol 24, Iss 1, Pp 30-37 (2023)
مصطلحات موضوعية: новая коронавирусная инфекция covid-19, дети, амбулаторное лечение, Pediatrics, RJ1-570, Gynecology and obstetrics, RG1-991
الوصف: The aim of the research – the comparative characteristics of the course of the new coronavirus infection (COVID-19) in children in different periods of the pandemic. Materials and methods. The comparative retrospective analysis of outpatient records of children in Novosibirsk was carried out. The first group includes patients who had the new coronavirus infection in October-December 2021 (the fourth wave of the pandemic). The second group consisted of patients with a registered infection in January-March 2022 (the fifth wave of incidence). The nature and severity of clinical symptoms of COVID-19, the presence of bacterial complications, the amount of drug therapy at the outpatient stage as well as the need to prescribe antibacterial agents were analyzed. Statistical processing of the material was carried out using the SPSS software package (version 26.0). Results. The clinical picture of the fourth wave of COVID-19 was characterized by nasal congestion, mucous nature of the nasal secretion, dry cough, pharyngoscopic signs of tonsillitis, auscultatory symptoms of bronchitis, development of the bacterial complications (acute otitis media, acute rhinosinusitis), longer disease duration, need for more medications, including systemic antibiotics. For the fifth wave of COVID-19, hoarseness, serous nasal discharge, symptoms of pharyngitis, faster recovery, use of fewer symptomatic therapies were typical. Conclusion. It has been reliably proven that COVID-19 in different periods of increased morbidity has specific clinical course, which must be taken into account when determining the tactics of managing patients in the pediatric area.
وصف الملف: electronic resource
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5دورية أكاديمية
المؤلفون: Юлия Олеговна Рождественская, Анастасия Владимировна Миронова, Ирина Владимировна Болгова, Яна Вячеславовна Юнкина, Светлана Ивановна Елгина, Вадим Гельевич Мозес, Елена Владимировна Рудаева, Наталья Степановна Черных, Кира Борисовна Мозес, Яэль Центер
المصدر: Мать и дитя в Кузбассе, Vol 24, Iss 1, Pp 85-88 (2023)
مصطلحات موضوعية: гемофилия а, эмицизубам, лечение, Pediatrics, RJ1-570, Gynecology and obstetrics, RG1-991
الوصف: Hemophilia is a disease caused by hereditary deficiency of plasma coagulation factors VIII (FVIII) (hemophilia A) or IX (FIX) (hemophilia B) and characterized by hematomic bleeding. The main therapeutic measures in patients with hemophilia are aimed at replacing the deficient factor both during hemorrhagic manifestations and for preventive purposes. Due to frequent transfusions of blood products, approximately 30 % of patients with hemophilia A develop antibodies to factor VIII. Antibodies block the procoagulant activity of the injected factors VIII and IX, and this may cause the ineffectiveness of hemostatic therapy in the usually accepted volumes. In October 2018, a new drug Emicizumab was registered in the territory of the Russian Federation, which is a bispecific humanized monoclonal antibodies based on immunoglobulin G4, which bind activated factor IX with factor X to replenish the function of the missing activated factor VIII. The article presents the first case in Kuzbass of using Emizizumab in a child with an inhibitory form of hemophilia A.
وصف الملف: electronic resource
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6دورية أكاديمية
المصدر: Опухоли женской репродуктивной системы, Vol 18, Iss 3, Pp 24-28 (2022)
مصطلحات موضوعية: рак молочной железы, послеоперационная лучевая терапия, рак молочной железы у больных старше 65 лет, органосохраняющее лечение рака молочной железы, Gynecology and obstetrics, RG1-991
الوصف: Postoperative radiation therapy after breast-conserving surgery is a standard method of treating breast cancer, but recently the issue of its de-escalation in patients older than 65 due to concomitant pathology, lower life expectancy and possible development of post-radiation complications has been discussed. The results of some foreign studies prove the absence of a statistically significant difference in relapse-free and overall survival in patients with early breast cancer older than 65 years with relatively favorable clinical and morphological characteristics without postoperative radiation therapy. We analyzed the long-term oncological results in patients with breast cancer older than 65 years after breast-conserving surgery without postoperative radiation therapy. The results of the study showed that postoperative radiation therapy in patients over 65 years of age with stage IA pT1N0M0 breast cancer of luminal immunophenotype A does not improve long-term oncological indicators. Thus, the exclusion of postoperative radiation therapy from the treatment plan of this group of patients is oncologically safe and economically justified.
وصف الملف: electronic resource
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7دورية أكاديمية
المؤلفون: Николай Ильич Никитин, Виктория Флоритовна Аллаярова, Индира Венеровна Сахаутдинова, Никита Александрович Ишмуратов
المصدر: Мать и дитя в Кузбассе, Vol 23, Iss 4, Pp 61-64 (2022)
مصطلحات موضوعية: кисты яичников, фолликулярный резерв, биполярная энергия, репродуктивный потенциал, оперативное лечение, Pediatrics, RJ1-570, Gynecology and obstetrics, RG1-991
الوصف: Benign ovarian tumors – volumetric formations growing from the ovarian tissue, occur at any age, reduce the reproductive potential of a woman, serve as an indication for surgical treatment, since they have a high risk of malignancy. The aim is to conduct a comparative assessment of the methods of surgical treatment of benign ovarian cysts and their effect on the follicular reserve. Materials and methods. For a comparative assessment of the traumatic impact on the inner surface of the cyst capsule, depending on the chosen surgical method, 37 patients with a benign ovarian tumor with a diameter of 3.5 cm to 8 cm were randomly selected. The candidates were divided into two groups depending on the surgical method used. The age interval of the observed was 18-49 years. Results. Ultrasound examination revealed that the formations were represented by endometrioid cysts and smooth-walled serous cystadenomas with a distribution of 11 and 8 patients from group No. 1, respectively. These pathologies in group No. 2 were distributed among 10 and 8 women. Among the most common gynecological pathologies in control patients were noted: inflammatory diseases of the appendages, the vaginal part of the cervix. Hormone therapy was carried out for 3-4 months for ovarian cysts, and only 30% of patients had a partial temporary effect. Patients did not receive hormone therapy during the study period. During a bimanual examination, moderate pain in the area of the appendages in the presence of a benign ovarian tumor was indicated by 12 (63.1 %) patients of the 1st and 10 (55.5 %) patients of the 2nd group. Conclusion. The impact of bipolar energy on the cyst capsule allows you to save healthy tissue and volume of the ovary, thereby subsequently contributing to the preservation of the ovarian reserve.
وصف الملف: electronic resource
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8دورية أكاديمية
المؤلفون: Елена Александровна Сидорова, Светлана Викторовна Цигельник, Наталья Владимировна Солдатова, Светлана Ивановна Елгина, Вадим Гельевич Мозес, Елена Владимировна Рудаева, Кира Борисовна Мозес
المصدر: Мать и дитя в Кузбассе, Vol 23, Iss 4, Pp 86-90 (2022)
مصطلحات موضوعية: интерстициальные заболевания лёгких, недоношенные новорожденные, клиника, диагностика, лечение, Pediatrics, RJ1-570, Gynecology and obstetrics, RG1-991
الوصف: Interstitial lung diseases (ISL), synonyms: diffuse lung diseases, diffuse parenchymal lung diseases, are a heterogeneous group of diseases in which alveoli and perialveolar interstitium are primarily involved in the pathological process, which leads to a violation of gas exchange, restretive violations of lung ventilation function and diffuse interstitial changes detected by X-ray examination. ISL is a rare pathology. It is believed that their true frequency is very difficult to determine, since due to the complexity of diagnosis, many cases remain unrecognized. Currently, it is believed that interstitial lung diseases occur at any age, but in children, they manifest in at least half of cases in the neonatal period or at the age of two years of life. In children under the age of one year, 2/3 of cases are due to diseases mainly occurring in the neonatal period. Submitted to а clinical case of a premature newborn girl with ISL diagnosed at the age of 1 month 11 days is presented. This clinical case indicates that it is necessary to work out the mechanism of making a decision to include interstitial lung diseases in the differential diagnostic search at an earlier stage.
وصف الملف: electronic resource
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9دورية أكاديمية
المؤلفون: A. L. Chernyshova, L. A. Kolomiets, Yu. M. Trushchuk, O. S. Dil, V. I. Chernov, E. S. Marchenko, T. L. Chekalkin, V. A. Antipov, S. E. Krasilnikov
المصدر: Опухоли женской репродуктивной системы, Vol 18, Iss 2, Pp 77-85 (2022)
مصطلحات موضوعية: радикальная трахелэктомия, органосохраняющее лечение, лапароскопия, лапаротомия, транспозиция, репродуктивные результаты, качество жизни, рак шейки матки, Gynecology and obstetrics, RG1-991
الوصف: Cervical cancer occupies a leading position in the structure of oncogynecological pathology. Radical trachelectomy (RT) has entered the standards of treatment of invasive cervical cancer in patients of reproductive age. RT can be performed by transabdominal and laparoscopic approaches. The purpose of our study was a comparative assessment of the effectiveness and study of the quality of life in patients after RT. In total, 99 surgical interventions were performed using technologies developed at Oncology Research Institute, Tomsk National Research Medical Center of Russian Academy of Sciences. The features and results of treatment are described, including oncological efficacy, reproductive results (reproductive potential, peculiarities of the course of pregnancies and childbirth). The analysis of the study of the quality of life of patients after RT according to the criteria of modern questionnaires EORTC QlQC30 and QLQ-CX24.
وصف الملف: electronic resource
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10دورية أكاديمية
المؤلفون: A. L. Chernyshova, L. A. Kolomiets, Yu. M. Trushchuk, O. V. Shpileva, E. V. Denisov, I. V. Larionova, Zh. A. Startseva, V. I. Chernov, E. S. Marchenko, T. L. Chekalkin, V. A. Antipov, S. E. Krasilnikov
المصدر: Опухоли женской репродуктивной системы, Vol 17, Iss 3, Pp 128-133 (2021)
مصطلحات موضوعية: шейка матки, рак, хирургическое лечение, лучевая терапия, гипертермия, трахелэктомия, органосохраняющее лечение, Gynecology and obstetrics, RG1-991
الوصف: Currently, approaches to the choice of treatment tactics for cervical cancer have changed significantly. According to the recommendations of ESGO (2018), RUSSCO (2020), the use of a combination of surgical treatment and radiation therapy significantly increases the incidence of complications. Therefore, when planning the treatment of patients with IB1–IIA1, a combination of surgical treatment and radiation therapy should be avoided. The article presents an analysis of modern approaches to the treatment of initial, locally advanced and advanced cervical cancer. Modern approaches to organ-preserving treatment are considered, including the view from the point of view of expanding the indications for trachelectomy as part of combined treatment. The question of the expediency of using hyperthermia and indications for this type of treatment in combination with radiation therapy is considered. The author presents his own view of the problem as a whole and possible ways to solve this problem.
وصف الملف: electronic resource
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