المؤلفون: Garcia-Pavia P; From Hospital Universitario Puerta de Hierro Majadahonda, IDIPHISA, CIBERCV, and Centro Nacional de Investigaciones Cardiovasculares, Madrid, and Universidad Francisco de Vitoria, Pozuelo de Alarcón - all in Spain (P.G.-P.); the Department of Cardiology, University Hospital Heidelberg, Heidelberg (F.S.), and Cardiovascular Center Darmstadt, Darmstadt (A.V.K.) - both in Germany; the Department of Cardiology, University of Rennes, Centre Hospitalier Universitaire (CHU) de Rennes, INSERM, LTSI-UMR 1099, Rennes (E.D.), Service de Cardiologie, CHU de Toulouse-Hôpital Rangueil, Toulouse (O.L.), and the Cardiology Department and French National Reference Center for Cardiac Amyloidosis, Hôpitaux Universitaires Henri Mondor, Assistance Publique-Hôpitaux de Paris, and Institut Mondor de Recherche Biomédicale, INSERM, Université Paris Est Créteil, Créteil (T.D.) - all in France; the Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands (P.M.); Alexion-AstraZeneca Rare Disease, Boston (M.F.M.); and Neurimmune (A.M., R.J.A.F., J.G., R.M.N., C.H., P.C.K.) and the Institute for Regenerative Medicine (R.M.N., C.H.) and the Center for Molecular Cardiology (P.C.K.), University of Zurich - all in Schlieren, Switzerland., Aus dem Siepen F; From Hospital Universitario Puerta de Hierro Majadahonda, IDIPHISA, CIBERCV, and Centro Nacional de Investigaciones Cardiovasculares, Madrid, and Universidad Francisco de Vitoria, Pozuelo de Alarcón - all in Spain (P.G.-P.); the Department of Cardiology, University Hospital Heidelberg, Heidelberg (F.S.), and Cardiovascular Center Darmstadt, Darmstadt (A.V.K.) - both in Germany; the Department of Cardiology, University of Rennes, Centre Hospitalier Universitaire (CHU) de Rennes, INSERM, LTSI-UMR 1099, Rennes (E.D.), Service de Cardiologie, CHU de Toulouse-Hôpital Rangueil, Toulouse (O.L.), and the Cardiology Department and French National Reference Center for Cardiac Amyloidosis, Hôpitaux Universitaires Henri Mondor, Assistance Publique-Hôpitaux de Paris, and Institut Mondor de Recherche Biomédicale, INSERM, Université Paris Est Créteil, Créteil (T.D.) - all in France; the Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands (P.M.); Alexion-AstraZeneca Rare Disease, Boston (M.F.M.); and Neurimmune (A.M., R.J.A.F., J.G., R.M.N., C.H., P.C.K.) and the Institute for Regenerative Medicine (R.M.N., C.H.) and the Center for Molecular Cardiology (P.C.K.), University of Zurich - all in Schlieren, Switzerland., Donal E; From Hospital Universitario Puerta de Hierro Majadahonda, IDIPHISA, CIBERCV, and Centro Nacional de Investigaciones Cardiovasculares, Madrid, and Universidad Francisco de Vitoria, Pozuelo de Alarcón - all in Spain (P.G.-P.); the Department of Cardiology, University Hospital Heidelberg, Heidelberg (F.S.), and Cardiovascular Center Darmstadt, Darmstadt (A.V.K.) - both in Germany; the Department of Cardiology, University of Rennes, Centre Hospitalier Universitaire (CHU) de Rennes, INSERM, LTSI-UMR 1099, Rennes (E.D.), Service de Cardiologie, CHU de Toulouse-Hôpital Rangueil, Toulouse (O.L.), and the Cardiology Department and French National Reference Center for Cardiac Amyloidosis, Hôpitaux Universitaires Henri Mondor, Assistance Publique-Hôpitaux de Paris, and Institut Mondor de Recherche Biomédicale, INSERM, Université Paris Est Créteil, Créteil (T.D.) - all in France; the Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands (P.M.); Alexion-AstraZeneca Rare Disease, Boston (M.F.M.); and Neurimmune (A.M., R.J.A.F., J.G., R.M.N., C.H., P.C.K.) and the Institute for Regenerative Medicine (R.M.N., C.H.) and the Center for Molecular Cardiology (P.C.K.), University of Zurich - all in Schlieren, Switzerland., Lairez O; From Hospital Universitario Puerta de Hierro Majadahonda, IDIPHISA, CIBERCV, and Centro Nacional de Investigaciones Cardiovasculares, Madrid, and Universidad Francisco de Vitoria, Pozuelo de Alarcón - all in Spain (P.G.-P.); the Department of Cardiology, University Hospital Heidelberg, Heidelberg (F.S.), and Cardiovascular Center Darmstadt, Darmstadt (A.V.K.) - both in Germany; the Department of Cardiology, University of Rennes, Centre Hospitalier Universitaire (CHU) de Rennes, INSERM, LTSI-UMR 1099, Rennes (E.D.), Service de Cardiologie, CHU de Toulouse-Hôpital Rangueil, Toulouse (O.L.), and the Cardiology Department and French National Reference Center for Cardiac Amyloidosis, Hôpitaux Universitaires Henri Mondor, Assistance Publique-Hôpitaux de Paris, and Institut Mondor de Recherche Biomédicale, INSERM, Université Paris Est Créteil, Créteil (T.D.) - all in France; the Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands (P.M.); Alexion-AstraZeneca Rare Disease, Boston (M.F.M.); and Neurimmune (A.M., R.J.A.F., J.G., R.M.N., C.H., P.C.K.) and the Institute for Regenerative Medicine (R.M.N., C.H.) and the Center for Molecular Cardiology (P.C.K.), University of Zurich - all in Schlieren, Switzerland., van der Meer P; From Hospital Universitario Puerta de Hierro Majadahonda, IDIPHISA, CIBERCV, and Centro Nacional de Investigaciones Cardiovasculares, Madrid, and Universidad Francisco de Vitoria, Pozuelo de Alarcón - all in Spain (P.G.-P.); the Department of Cardiology, University Hospital Heidelberg, Heidelberg (F.S.), and Cardiovascular Center Darmstadt, Darmstadt (A.V.K.) - both in Germany; the Department of Cardiology, University of Rennes, Centre Hospitalier Universitaire (CHU) de Rennes, INSERM, LTSI-UMR 1099, Rennes (E.D.), Service de Cardiologie, CHU de Toulouse-Hôpital Rangueil, Toulouse (O.L.), and the Cardiology Department and French National Reference Center for Cardiac Amyloidosis, Hôpitaux Universitaires Henri Mondor, Assistance Publique-Hôpitaux de Paris, and Institut Mondor de Recherche Biomédicale, INSERM, Université Paris Est Créteil, Créteil (T.D.) - all in France; the Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands (P.M.); Alexion-AstraZeneca Rare Disease, Boston (M.F.M.); and Neurimmune (A.M., R.J.A.F., J.G., R.M.N., C.H., P.C.K.) and the Institute for Regenerative Medicine (R.M.N., C.H.) and the Center for Molecular Cardiology (P.C.K.), University of Zurich - all in Schlieren, Switzerland., Kristen AV; From Hospital Universitario Puerta de Hierro Majadahonda, IDIPHISA, CIBERCV, and Centro Nacional de Investigaciones Cardiovasculares, Madrid, and Universidad Francisco de Vitoria, Pozuelo de Alarcón - all in Spain (P.G.-P.); the Department of Cardiology, University Hospital Heidelberg, Heidelberg (F.S.), and Cardiovascular Center Darmstadt, Darmstadt (A.V.K.) - both in Germany; the Department of Cardiology, University of Rennes, Centre Hospitalier Universitaire (CHU) de Rennes, INSERM, LTSI-UMR 1099, Rennes (E.D.), Service de Cardiologie, CHU de Toulouse-Hôpital Rangueil, Toulouse (O.L.), and the Cardiology Department and French National Reference Center for Cardiac Amyloidosis, Hôpitaux Universitaires Henri Mondor, Assistance Publique-Hôpitaux de Paris, and Institut Mondor de Recherche Biomédicale, INSERM, Université Paris Est Créteil, Créteil (T.D.) - all in France; the Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands (P.M.); Alexion-AstraZeneca Rare Disease, Boston (M.F.M.); and Neurimmune (A.M., R.J.A.F., J.G., R.M.N., C.H., P.C.K.) and the Institute for Regenerative Medicine (R.M.N., C.H.) and the Center for Molecular Cardiology (P.C.K.), University of Zurich - all in Schlieren, Switzerland., Mercuri MF; From Hospital Universitario Puerta de Hierro Majadahonda, IDIPHISA, CIBERCV, and Centro Nacional de Investigaciones Cardiovasculares, Madrid, and Universidad Francisco de Vitoria, Pozuelo de Alarcón - all in Spain (P.G.-P.); the Department of Cardiology, University Hospital Heidelberg, Heidelberg (F.S.), and Cardiovascular Center Darmstadt, Darmstadt (A.V.K.) - both in Germany; the Department of Cardiology, University of Rennes, Centre Hospitalier Universitaire (CHU) de Rennes, INSERM, LTSI-UMR 1099, Rennes (E.D.), Service de Cardiologie, CHU de Toulouse-Hôpital Rangueil, Toulouse (O.L.), and the Cardiology Department and French National Reference Center for Cardiac Amyloidosis, Hôpitaux Universitaires Henri Mondor, Assistance Publique-Hôpitaux de Paris, and Institut Mondor de Recherche Biomédicale, INSERM, Université Paris Est Créteil, Créteil (T.D.) - all in France; the Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands (P.M.); Alexion-AstraZeneca Rare Disease, Boston (M.F.M.); and Neurimmune (A.M., R.J.A.F., J.G., R.M.N., C.H., P.C.K.) and the Institute for Regenerative Medicine (R.M.N., C.H.) and the Center for Molecular Cardiology (P.C.K.), University of Zurich - all in Schlieren, Switzerland., Michalon A; From Hospital Universitario Puerta de Hierro Majadahonda, IDIPHISA, CIBERCV, and Centro Nacional de Investigaciones Cardiovasculares, Madrid, and Universidad Francisco de Vitoria, Pozuelo de Alarcón - all in Spain (P.G.-P.); the Department of Cardiology, University Hospital Heidelberg, Heidelberg (F.S.), and Cardiovascular Center Darmstadt, Darmstadt (A.V.K.) - both in Germany; the Department of Cardiology, University of Rennes, Centre Hospitalier Universitaire (CHU) de Rennes, INSERM, LTSI-UMR 1099, Rennes (E.D.), Service de Cardiologie, CHU de Toulouse-Hôpital Rangueil, Toulouse (O.L.), and the Cardiology Department and French National Reference Center for Cardiac Amyloidosis, Hôpitaux Universitaires Henri Mondor, Assistance Publique-Hôpitaux de Paris, and Institut Mondor de Recherche Biomédicale, INSERM, Université Paris Est Créteil, Créteil (T.D.) - all in France; the Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands (P.M.); Alexion-AstraZeneca Rare Disease, Boston (M.F.M.); and Neurimmune (A.M., R.J.A.F., J.G., R.M.N., C.H., P.C.K.) and the Institute for Regenerative Medicine (R.M.N., C.H.) and the Center for Molecular Cardiology (P.C.K.), University of Zurich - all in Schlieren, Switzerland., Frost RJA; From Hospital Universitario Puerta de Hierro Majadahonda, IDIPHISA, CIBERCV, and Centro Nacional de Investigaciones Cardiovasculares, Madrid, and Universidad Francisco de Vitoria, Pozuelo de Alarcón - all in Spain (P.G.-P.); the Department of Cardiology, University Hospital Heidelberg, Heidelberg (F.S.), and Cardiovascular Center Darmstadt, Darmstadt (A.V.K.) - both in Germany; the Department of Cardiology, University of Rennes, Centre Hospitalier Universitaire (CHU) de Rennes, INSERM, LTSI-UMR 1099, Rennes (E.D.), Service de Cardiologie, CHU de Toulouse-Hôpital Rangueil, Toulouse (O.L.), and the Cardiology Department and French National Reference Center for Cardiac Amyloidosis, Hôpitaux Universitaires Henri Mondor, Assistance Publique-Hôpitaux de Paris, and Institut Mondor de Recherche Biomédicale, INSERM, Université Paris Est Créteil, Créteil (T.D.) - all in France; the Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands (P.M.); Alexion-AstraZeneca Rare Disease, Boston (M.F.M.); and Neurimmune (A.M., R.J.A.F., J.G., R.M.N., C.H., P.C.K.) and the Institute for Regenerative Medicine (R.M.N., C.H.) and the Center for Molecular Cardiology (P.C.K.), University of Zurich - all in Schlieren, Switzerland., Grimm J; From Hospital Universitario Puerta de Hierro Majadahonda, IDIPHISA, CIBERCV, and Centro Nacional de Investigaciones Cardiovasculares, Madrid, and Universidad Francisco de Vitoria, Pozuelo de Alarcón - all in Spain (P.G.-P.); the Department of Cardiology, University Hospital Heidelberg, Heidelberg (F.S.), and Cardiovascular Center Darmstadt, Darmstadt (A.V.K.) - both in Germany; the Department of Cardiology, University of Rennes, Centre Hospitalier Universitaire (CHU) de Rennes, INSERM, LTSI-UMR 1099, Rennes (E.D.), Service de Cardiologie, CHU de Toulouse-Hôpital Rangueil, Toulouse (O.L.), and the Cardiology Department and French National Reference Center for Cardiac Amyloidosis, Hôpitaux Universitaires Henri Mondor, Assistance Publique-Hôpitaux de Paris, and Institut Mondor de Recherche Biomédicale, INSERM, Université Paris Est Créteil, Créteil (T.D.) - all in France; the Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands (P.M.); Alexion-AstraZeneca Rare Disease, Boston (M.F.M.); and Neurimmune (A.M., R.J.A.F., J.G., R.M.N., C.H., P.C.K.) and the Institute for Regenerative Medicine (R.M.N., C.H.) and the Center for Molecular Cardiology (P.C.K.), University of Zurich - all in Schlieren, Switzerland., Nitsch RM; From Hospital Universitario Puerta de Hierro Majadahonda, IDIPHISA, CIBERCV, and Centro Nacional de Investigaciones Cardiovasculares, Madrid, and Universidad Francisco de Vitoria, Pozuelo de Alarcón - all in Spain (P.G.-P.); the Department of Cardiology, University Hospital Heidelberg, Heidelberg (F.S.), and Cardiovascular Center Darmstadt, Darmstadt (A.V.K.) - both in Germany; the Department of Cardiology, University of Rennes, Centre Hospitalier Universitaire (CHU) de Rennes, INSERM, LTSI-UMR 1099, Rennes (E.D.), Service de Cardiologie, CHU de Toulouse-Hôpital Rangueil, Toulouse (O.L.), and the Cardiology Department and French National Reference Center for Cardiac Amyloidosis, Hôpitaux Universitaires Henri Mondor, Assistance Publique-Hôpitaux de Paris, and Institut Mondor de Recherche Biomédicale, INSERM, Université Paris Est Créteil, Créteil (T.D.) - all in France; the Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands (P.M.); Alexion-AstraZeneca Rare Disease, Boston (M.F.M.); and Neurimmune (A.M., R.J.A.F., J.G., R.M.N., C.H., P.C.K.) and the Institute for Regenerative Medicine (R.M.N., C.H.) and the Center for Molecular Cardiology (P.C.K.), University of Zurich - all in Schlieren, Switzerland., Hock C; From Hospital Universitario Puerta de Hierro Majadahonda, IDIPHISA, CIBERCV, and Centro Nacional de Investigaciones Cardiovasculares, Madrid, and Universidad Francisco de Vitoria, Pozuelo de Alarcón - all in Spain (P.G.-P.); the Department of Cardiology, University Hospital Heidelberg, Heidelberg (F.S.), and Cardiovascular Center Darmstadt, Darmstadt (A.V.K.) - both in Germany; the Department of Cardiology, University of Rennes, Centre Hospitalier Universitaire (CHU) de Rennes, INSERM, LTSI-UMR 1099, Rennes (E.D.), Service de Cardiologie, CHU de Toulouse-Hôpital Rangueil, Toulouse (O.L.), and the Cardiology Department and French National Reference Center for Cardiac Amyloidosis, Hôpitaux Universitaires Henri Mondor, Assistance Publique-Hôpitaux de Paris, and Institut Mondor de Recherche Biomédicale, INSERM, Université Paris Est Créteil, Créteil (T.D.) - all in France; the Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands (P.M.); Alexion-AstraZeneca Rare Disease, Boston (M.F.M.); and Neurimmune (A.M., R.J.A.F., J.G., R.M.N., C.H., P.C.K.) and the Institute for Regenerative Medicine (R.M.N., C.H.) and the Center for Molecular Cardiology (P.C.K.), University of Zurich - all in Schlieren, Switzerland., Kahr PC; From Hospital Universitario Puerta de Hierro Majadahonda, IDIPHISA, CIBERCV, and Centro Nacional de Investigaciones Cardiovasculares, Madrid, and Universidad Francisco de Vitoria, Pozuelo de Alarcón - all in Spain (P.G.-P.); the Department of Cardiology, University Hospital Heidelberg, Heidelberg (F.S.), and Cardiovascular Center Darmstadt, Darmstadt (A.V.K.) - both in Germany; the Department of Cardiology, University of Rennes, Centre Hospitalier Universitaire (CHU) de Rennes, INSERM, LTSI-UMR 1099, Rennes (E.D.), Service de Cardiologie, CHU de Toulouse-Hôpital Rangueil, Toulouse (O.L.), and the Cardiology Department and French National Reference Center for Cardiac Amyloidosis, Hôpitaux Universitaires Henri Mondor, Assistance Publique-Hôpitaux de Paris, and Institut Mondor de Recherche Biomédicale, INSERM, Université Paris Est Créteil, Créteil (T.D.) - all in France; the Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands (P.M.); Alexion-AstraZeneca Rare Disease, Boston (M.F.M.); and Neurimmune (A.M., R.J.A.F., J.G., R.M.N., C.H., P.C.K.) and the Institute for Regenerative Medicine (R.M.N., C.H.) and the Center for Molecular Cardiology (P.C.K.), University of Zurich - all in Schlieren, Switzerland., Damy T; From Hospital Universitario Puerta de Hierro Majadahonda, IDIPHISA, CIBERCV, and Centro Nacional de Investigaciones Cardiovasculares, Madrid, and Universidad Francisco de Vitoria, Pozuelo de Alarcón - all in Spain (P.G.-P.); the Department of Cardiology, University Hospital Heidelberg, Heidelberg (F.S.), and Cardiovascular Center Darmstadt, Darmstadt (A.V.K.) - both in Germany; the Department of Cardiology, University of Rennes, Centre Hospitalier Universitaire (CHU) de Rennes, INSERM, LTSI-UMR 1099, Rennes (E.D.), Service de Cardiologie, CHU de Toulouse-Hôpital Rangueil, Toulouse (O.L.), and the Cardiology Department and French National Reference Center for Cardiac Amyloidosis, Hôpitaux Universitaires Henri Mondor, Assistance Publique-Hôpitaux de Paris, and Institut Mondor de Recherche Biomédicale, INSERM, Université Paris Est Créteil, Créteil (T.D.) - all in France; the Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands (P.M.); Alexion-AstraZeneca Rare Disease, Boston (M.F.M.); and Neurimmune (A.M., R.J.A.F., J.G., R.M.N., C.H., P.C.K.) and the Institute for Regenerative Medicine (R.M.N., C.H.) and the Center for Molecular Cardiology (P.C.K.), University of Zurich - all in Schlieren, Switzerland.

المصدر: The New England journal of medicine [N Engl J Med] 2023 Jul 20; Vol. 389 (3), pp. 239-250. Date of Electronic Publication: 2023 May 20.

نوع المنشور: Clinical Trial, Phase I; Randomized Controlled Trial; Journal Article

بيانات الدورية: Publisher: Massachusetts Medical Society Country of Publication: United States NLM ID: 0255562 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1533-4406 (Electronic) Linking ISSN: 00284793 NLM ISO Abbreviation: N Engl J Med Subsets: MEDLINE

مواضيع طبية MeSH: Amyloid Neuropathies, Familial*/diagnostic imaging , Amyloid Neuropathies, Familial*/drug therapy , Amyloid Neuropathies, Familial*/complications , Antibodies*/administration & dosage , Antibodies*/adverse effects , Antibodies*/pharmacology , Antibodies*/therapeutic use , Cardiomyopathies*/diagnostic imaging , Cardiomyopathies*/drug therapy , Cardiomyopathies*/etiology , Heart Failure*/diagnostic imaging , Heart Failure*/drug therapy , Heart Failure*/etiology , Recombinant Proteins*/administration & dosage , Recombinant Proteins*/adverse effects , Recombinant Proteins*/pharmacokinetics , Recombinant Proteins*/therapeutic use, Humans ; Magnetic Resonance Imaging ; Prealbumin ; Double-Blind Method ; Chronic Disease ; Infusions, Intravenous

SCR Disease Name: Amyloidosis, Hereditary, Transthyretin-Related

المؤلفون: Dorbala S; Cardiac Amyloidosis Program, Cardiovascular Imaging Programs, Departments of Medicine and Radiology, Harvard Medical School, Brigham and Women's Hospital, Boston, Massachusetts., Ando Y; Department of Neurology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan., Bokhari S; Columbia University Medical Center, New York Presbyterian Hospital, Columbia University, New York, New York., Dispenzieri A; Division of Hematology, Division of Cardiovascular Diseases, Department of Radiology, Division of Nuclear Medicine, Department of Medicine, Mayo Clinic, Rochester, Minnesota., Falk RH; Cardiac Amyloidosis Program, Cardiovascular Imaging Programs, Departments of Medicine and Radiology, Harvard Medical School, Brigham and Women's Hospital, Boston, Massachusetts., Ferrari VA; Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Fontana M; Division of Medicine, National Amyloidosis Centre, University College London, London, UK., Gheysens O; University Hospitals Leuven, Nuclear Medicine and Molecular Imaging, Leuven, Belgium., Gillmore JD; Division of Medicine, National Amyloidosis Centre, University College London, London, UK., Glaudemans AWJM; Department of Nuclear Medicine and Molecular Imaging, Medical Imaging Center, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Hanna MA; Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, Ohio., Hazenberg BPC; Department of Rheumatology & Clinical Immunology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Kristen AV; Department of Cardiology, University of Heidelberg, Heidelberg, Germany., Kwong RY; Cardiac Amyloidosis Program, Cardiovascular Imaging Programs, Departments of Medicine and Radiology, Harvard Medical School, Brigham and Women's Hospital, Boston, Massachusetts., Maurer MS; Columbia University Medical Center, New York Presbyterian Hospital, Columbia University, New York, New York., Merlini G; Foundation Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo, Amyloidosis Research and Treatment Center, Pavia, Italy; Department of Molecular Medicine, University of Pavia, Pavia, Italy., Miller EJ; Cardiovascular Medicine, Yale University School of Medicine, New Haven, Connecticut., Moon JC; Division of Medicine, National Amyloidosis Centre, University College London, London, UK., Murthy VL; Frankel Cardiovascular Center, Michigan Medicine, Ann Arbor, Michigan., Quarta CC; Division of Medicine, National Amyloidosis Centre, University College London, London, UK., Rapezzi C; Cardiology Unit, Department of Experimental, Diagnostic and Specialty Medicine, Alma Mater-University of Bologna, Bologna, Italy., Ruberg FL; Department of Medicine, Amyloidosis Center and Section of Cardiovascular Medicine, Boston Medical Center, Boston University School of Medicine, Boston, Massachusetts., Shah SJ; Feinberg School of Medicine, Northwestern University, Chicago, Illinois., Slart RHJA; Department of Nuclear Medicine and Molecular Imaging, Medical Imaging Center, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Verberne HJ; Department of Radiology and Nuclear Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands., Bourque JM; Departments of Medicine and Radiology, Cardiovascular Imaging Center, University of Virginia, Charlottesville, Virginia. Electronic address: JMB8T@hscmail.mcc.virginia.edu.

المصدر: Journal of cardiac failure [J Card Fail] 2022 Jul; Vol. 28 (7), pp. e1-e4. Date of Electronic Publication: 2021 Jul 01.

نوع المنشور: Journal Article; Published Erratum

بيانات الدورية: Publisher: Churchill Livingstone Country of Publication: United States NLM ID: 9442138 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-8414 (Electronic) Linking ISSN: 10719164 NLM ISO Abbreviation: J Card Fail Subsets: MEDLINE

مواضيع طبية MeSH: Amyloidosis*/diagnostic imaging , Amyloidosis*/therapy , Heart Failure*, American Heart Association ; Consensus ; Humans ; Multimodal Imaging/methods ; United States

المؤلفون: Caponetti AG; Department of Experimental, Diagnostic, and Specialty Medicine, University of Bologna, Italy., Rapezzi C; Cardiological Center, University of Ferrara, Ferrara, Italy; Maria Cecilia Hospital, GVM Care and Research, Cotignola, Emilia-Romagna, Italy. Electronic address: Claudio.rapezzi@unibo.it., Gagliardi C; Department of Experimental, Diagnostic, and Specialty Medicine, University of Bologna, Italy., Milandri A; Department of Cardiology, Bentivoglio Hospital, Bentivoglio, Bologna, Italy., Dispenzieri A; Division of Hematology, Mayo Clinic, Rochester, Minnesota, USA., Kristen AV; Department of Cardiology, Angiology, Respiratory Medicine, Medical University of Heidelberg, Heidelberg, Germany., Wixner J; Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden., Maurer MS; Columbia University College of Physicians and Surgeons, New York, New York, USA., Garcia-Pavia P; Department of Cardiology, Hospital Universitario Puerta de Hierro Majadahonda, Centro de Investigación Biomédica en Red Enfermedades Cardiovasculares, Madrid, Spain; Universidad Francisco de Vitoria, Pozuelo de Alarcon, Madrid, Spain., Tournev I; Clinic of Nervous Diseases, University Hospital Aleksandrovska, Sofia, Bulgaria; Department of Neurology, Medical University, Sofia, Bulgaria; Department of Cognitive Science and Psychology, New Bulgarian University, Sofia, Bulgaria., Planté-Bordeneuve V; Department of Neurology- Amyloid Network-University Hospital Henri Mondor-Assistance Publique Hopitaux de Paris, IMRB INSERM U955 Team 10 'Biology of the Neuro-Muscular System', Créteil, France., Chapman D; Pfizer, New York, New York, USA., Amass L; Pfizer, New York, New York, USA.

مؤلفون مشاركون: THAOS Investigators

المصدر: JACC. Heart failure [JACC Heart Fail] 2021 Oct; Vol. 9 (10), pp. 736-746. Date of Electronic Publication: 2021 Aug 11.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 101598241 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-1787 (Electronic) Linking ISSN: 22131779 NLM ISO Abbreviation: JACC Heart Fail Subsets: MEDLINE

مواضيع طبية MeSH: Amyloid Neuropathies, Familial*/complications , Amyloid Neuropathies, Familial*/epidemiology , Amyloid Neuropathies, Familial*/genetics , Heart Failure*, Female ; Humans ; Male ; Prealbumin/genetics ; Surveys and Questionnaires

SCR Disease Name: Amyloidosis, Hereditary, Transthyretin-Related

المؤلفون: Garcia-Pavia P; Heart Failure and Inherited Cardiac Diseases Unit, Department of Cardiology, Hospital Universitario Puerta de Hierro Majadahonda, CIBERCV, Madrid, Spain.; Universidad Francisco de Vitoria (UFV), Pozuelo de Alarcon, Spain.; European Reference Network for Rare, Low Prevalence and Complex Diseases of the Heart-ERN GUARD-Heart., Rapezzi C; Cardiologic Centre, University of Ferrara, Ferrara, Italy.; Maria Cecilia Hospital, GVM Care & Research, Cotignola, Italy., Adler Y; Leviev Heart Centre, Chaim Sheba Medical Centre (affiliated to Tel Aviv University), Ramat Gan, Israel., Arad M; Heart Failure Institute, Leviev Heart Centre, Sheba Hospital and Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel., Basso C; European Reference Network for Rare, Low Prevalence and Complex Diseases of the Heart-ERN GUARD-Heart.; Cardiovascular Pathology Unit, University Hospital, and Department of Cardiac, Thoracic and Vascular Sciences and Public Health, University of Padua, Padua, Italy., Brucato A; Department of Biomedical and Clinical Sciences, University of Milan, Fatebenefratelli Hospital, Milan, Italy., Burazor I; Belgrade University School of Medicine, Cardiology, Institute for Rehabilitation, Belgrade, Serbia., Caforio ALP; European Reference Network for Rare, Low Prevalence and Complex Diseases of the Heart-ERN GUARD-Heart.; Cardiology, Department of Cardiac, Thoracic and Vascular Sciences and Public Health, University of Padua, Padua, Italy., Damy T; French Referral Centre for Cardiac Amyloidosis, Amyloidosis Mondor Network, GRC Amyloid Research Institute, CHU Henri Mondor, Créteil, France., Eriksson U; GZO - Zurich Regional Health Centre, Wetzikon & Cardioimmunology, Centre for Molecular Cardiology, University of Zurich, Zurich, Switzerland., Fontana M; National Amyloidosis Centre, Division of Medicine, University College London, Royal Free Hospital, London, UK., Gillmore JD; National Amyloidosis Centre, Division of Medicine, University College London, Royal Free Hospital, London, UK., Gonzalez-Lopez E; Heart Failure and Inherited Cardiac Diseases Unit, Department of Cardiology, Hospital Universitario Puerta de Hierro Majadahonda, CIBERCV, Madrid, Spain.; European Reference Network for Rare, Low Prevalence and Complex Diseases of the Heart-ERN GUARD-Heart., Grogan M; Cardiac Amyloid Clinic, Division of Circulatory Failure, Department of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, USA., Heymans S; Department of Cardiology, Maastricht University, CARIM School for Cardiovascular Diseases, Maastricht, The Netherlands.; Centre for Molecular and Vascular Biology, KU Leuven, Leuven, Belgium.; ICIN-Netherlands Heart Institute, Holland Heart House, Utrecht, The Netherlands., Imazio M; University Cardiology, Cardiovascular and Thoracic Department, AOU Città della Salute e della Scienza di Torino, Turin, Italy., Kindermann I; Department of Internal Medicine III (Cardiology, Angiology and Intensive Care), Saarland University Medical Centre, Saarland University, Homburg, Germany., Kristen AV; Department of Cardiology, University of Heidelberg, Heidelberg, Germany.; Cardiovascular Centre Darmstadt, Heidelberg, Germany., Maurer MS; Cardiac Amyloidosis Program, Centre for Advanced Cardiac Care, Columbia University Irving Medical Centre, New York Presbyterian Hospital, New York, NY, USA., Merlini G; Amyloidosis Research and Treatment Centre, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.; Department of Molecular Medicine, University of Pavia, Pavia, Italy., Pantazis A; Cardiomyopathy Service, Royal Brompton Hospital, London, UK., Pankuweit S; Department of Cardiology, Philipps-University Marburg, Marburg, Germany., Rigopoulos AG; Mid-German Heart Centre, Department of Internal Medicine III, Division of Cardiology, Angiology and Intensive Medical Care, University Hospital Halle, Martin-Luther-University Halle-Wittenberg, Halle (Saale), Germany., Linhart A; 2nd Department of Medicine, Department of Cardiovascular Medicine, First Faculty of Medicine, Charles University, General University Hospital, Prague, Czech Republic.

المصدر: European journal of heart failure [Eur J Heart Fail] 2021 Apr; Vol. 23 (4), pp. 512-526. Date of Electronic Publication: 2021 Apr 07.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley Country of Publication: England NLM ID: 100887595 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0844 (Electronic) Linking ISSN: 13889842 NLM ISO Abbreviation: Eur J Heart Fail Subsets: MEDLINE

مواضيع طبية MeSH: Amyloidosis* , Cardiology* , Cardiomyopathies* , Heart Diseases* , Heart Failure*, Humans ; Myocardium

المؤلفون: Arenja N; Department of Cardiology, Angiology and Pneumology, University of Heidelberg, Im Neuenheimer Feld 410, Heidelberg 69120, Germany.; Department of Cardiology, Solothurner Spitäler AG, Kantonsspital Olten, Switzerland., Fritz T; Department of Cardiology, Angiology and Pneumology, University of Heidelberg, Im Neuenheimer Feld 410, Heidelberg 69120, Germany., Andre F; Department of Cardiology, Angiology and Pneumology, University of Heidelberg, Im Neuenheimer Feld 410, Heidelberg 69120, Germany., Riffel JH; Department of Cardiology, Angiology and Pneumology, University of Heidelberg, Im Neuenheimer Feld 410, Heidelberg 69120, Germany., Aus dem Siepen F; Department of Cardiology, Angiology and Pneumology, University of Heidelberg, Im Neuenheimer Feld 410, Heidelberg 69120, Germany., Ochs M; Department of Cardiology, Angiology and Pneumology, University of Heidelberg, Im Neuenheimer Feld 410, Heidelberg 69120, Germany., Paffhausen J; Department of Cardiology, Angiology and Pneumology, University of Heidelberg, Im Neuenheimer Feld 410, Heidelberg 69120, Germany., Hegenbart U; Department of Hematology, University of Heidelberg, Im Neuenheimer Feld 410, Heidelberg 69120, Germany., Schönland S; Department of Hematology, University of Heidelberg, Im Neuenheimer Feld 410, Heidelberg 69120, Germany., Müller-Hennessen M; Department of Cardiology, Angiology and Pneumology, University of Heidelberg, Im Neuenheimer Feld 410, Heidelberg 69120, Germany., Giannitsis E; Department of Cardiology, Angiology and Pneumology, University of Heidelberg, Im Neuenheimer Feld 410, Heidelberg 69120, Germany., Kristen AV; Department of Cardiology, Angiology and Pneumology, University of Heidelberg, Im Neuenheimer Feld 410, Heidelberg 69120, Germany., Katus HA; Department of Cardiology, Angiology and Pneumology, University of Heidelberg, Im Neuenheimer Feld 410, Heidelberg 69120, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Heidelberg, Germany., Friedrich MG; Department of Cardiology, Angiology and Pneumology, University of Heidelberg, Im Neuenheimer Feld 410, Heidelberg 69120, Germany., Buss SJ; Department of Cardiology, Angiology and Pneumology, University of Heidelberg, Im Neuenheimer Feld 410, Heidelberg 69120, Germany.; Das Radiologische Zentrum - Radiology Center Sinsheim-Eberbach-Erbach-Walldorf-Heidelberg, Germany.

المصدر: European heart journal. Cardiovascular Imaging [Eur Heart J Cardiovasc Imaging] 2017 Dec 01; Vol. 18 (12), pp. 1414-1422.

نوع المنشور: Comparative Study; Journal Article

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 101573788 Publication Model: Print Cited Medium: Internet ISSN: 2047-2412 (Electronic) Linking ISSN: 20472404 NLM ISO Abbreviation: Eur Heart J Cardiovasc Imaging Subsets: MEDLINE

مواضيع طبية MeSH: Heart Failure/*diagnostic imaging , Hypertension/*diagnostic imaging , Hypertrophy, Left Ventricular/*diagnostic imaging , Magnetic Resonance Imaging, Cine/*methods , Myocardial Contraction/*physiology, Age Factors ; Amyloidosis/diagnostic imaging ; Amyloidosis/epidemiology ; Amyloidosis/physiopathology ; Area Under Curve ; Case-Control Studies ; Chi-Square Distribution ; Diagnosis, Differential ; Female ; Heart Failure/epidemiology ; Heart Failure/physiopathology ; Hospitals, University ; Humans ; Hypertension/epidemiology ; Hypertension/physiopathology ; Hypertrophy, Left Ventricular/epidemiology ; Hypertrophy, Left Ventricular/physiopathology ; Male ; Prognosis ; ROC Curve ; Reference Values ; Retrospective Studies ; Risk Assessment ; Sensitivity and Specificity ; Severity of Illness Index ; Sex Factors ; Stroke Volume/physiology

المؤلفون: Aus dem Siepen F; a Department of Cardiology , University Hospital Heidelberg , Heidelberg , Germany., Hein S; a Department of Cardiology , University Hospital Heidelberg , Heidelberg , Germany., Bauer R; a Department of Cardiology , University Hospital Heidelberg , Heidelberg , Germany., Katus HA; a Department of Cardiology , University Hospital Heidelberg , Heidelberg , Germany., Kristen AV; a Department of Cardiology , University Hospital Heidelberg , Heidelberg , Germany.

المصدر: Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis [Amyloid] 2017 Mar; Vol. 24 (sup1), pp. 132-133.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Taylor & Francis Country of Publication: England NLM ID: 9433802 Publication Model: Print Cited Medium: Internet ISSN: 1744-2818 (Electronic) Linking ISSN: 13506129 NLM ISO Abbreviation: Amyloid Subsets: MEDLINE

مواضيع طبية MeSH: Amyloid Neuropathies, Familial/*drug therapy , Heart Failure/*drug therapy, Aged ; Amyloid Neuropathies, Familial/metabolism ; Amyloid Neuropathies, Familial/mortality ; Angiotensin-Converting Enzyme Inhibitors/therapeutic use ; Female ; Heart Failure/metabolism ; Heart Failure/mortality ; Humans ; Kaplan-Meier Estimate ; Male ; Middle Aged ; Retrospective Studies

SCR Disease Name: Amyloidosis, Hereditary, Transthyretin-Related

المؤلفون: Damy T; Department of Cardiology, University Hospital Henri Mondor, Amyloidosis Mondor Network, DHU ATVB, Créteil, France, thibaud.damy@hmn.aphp.fr., Judge DP, Kristen AV, Berthet K, Li H, Aarts J

المصدر: Journal of cardiovascular translational research [J Cardiovasc Transl Res] 2015 Mar; Vol. 8 (2), pp. 117-27. Date of Electronic Publication: 2015 Mar 06.

نوع المنشور: Clinical Trial, Phase II; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Springer Country of Publication: United States NLM ID: 101468585 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1937-5395 (Electronic) Linking ISSN: 19375387 NLM ISO Abbreviation: J Cardiovasc Transl Res Subsets: MEDLINE

مواضيع طبية MeSH: Mutation*, Amyloid Neuropathies, Familial/*drug therapy , Amyloid Neuropathies, Familial/*genetics , Benzoxazoles/*therapeutic use , Cardiomyopathies/*genetics , Heart Failure/*genetics , Myocardium/*pathology , Prealbumin/*genetics, Adult ; Aged ; Amyloid Neuropathies, Familial/diagnosis ; Amyloid Neuropathies, Familial/physiopathology ; Benzoxazoles/adverse effects ; Cardiomyopathies/diagnosis ; Cardiomyopathies/physiopathology ; Europe ; Female ; Fibrosis ; Genetic Predisposition to Disease ; Heart Failure/diagnosis ; Heart Failure/physiopathology ; Humans ; Male ; Middle Aged ; Phenotype ; Risk Factors ; Time Factors ; Treatment Outcome ; United States

SCR Disease Name: Amyloidosis, Hereditary, Transthyretin-Related

المؤلفون: Kristen AV; Department of Cardiology, University of Heidelberg, Heidelberg, Germany., Schuhmacher B, Strych K, Lossnitzer D, Friederich HC, Hilbel T, Haass M, Katus HA, Schneider A, Streitberger KM, Backs J

المصدر: Heart (British Cardiac Society) [Heart] 2010 Sep; Vol. 96 (17), pp. 1396-400. Date of Electronic Publication: 2010 Jun 15.

نوع المنشور: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: BMJ Pub. Group Country of Publication: England NLM ID: 9602087 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1468-201X (Electronic) Linking ISSN: 13556037 NLM ISO Abbreviation: Heart Subsets: MEDLINE

مواضيع طبية MeSH: Acupuncture Therapy/*methods , Exercise Tolerance/*physiology , Heart Failure/*therapy, Aged ; Autonomic Nervous System/physiopathology ; Cytokines/blood ; Exercise Test/methods ; Female ; Heart Failure/physiopathology ; Heart Rate/physiology ; Humans ; Inflammation Mediators/blood ; Male ; Middle Aged ; Prospective Studies ; Quality of Life ; Single-Blind Method ; Treatment Outcome

المؤلفون: Kristen AV; Department of Cardiology, Medical University of Heidelberg, Heidelberg, Germany., Kreusser MM, Lehmann L, Kinscherf R, Katus HA, Haass M, Backs J

المصدر: Journal of cardiac failure [J Card Fail] 2006 Sep; Vol. 12 (7), pp. 577-83.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Churchill Livingstone Country of Publication: United States NLM ID: 9442138 Publication Model: Print Cited Medium: Internet ISSN: 1532-8414 (Electronic) Linking ISSN: 10719164 NLM ISO Abbreviation: J Card Fail Subsets: MEDLINE

مواضيع طبية MeSH: Heart Failure/*metabolism , Heart Failure/*pathology , Hypertension/*complications , Myocardium/*metabolism , Nerve Endings/*pathology , Norepinephrine/*metabolism , Sympathetic Nervous System/*pathology, Animals ; Aorta/surgery ; Arteriovenous Shunt, Surgical ; Cardiomegaly/etiology ; Heart Failure/etiology ; Homeostasis ; Male ; Rats ; Rats, Wistar ; Venae Cavae

المؤلفون: Backs J; Department of Cardiology, University of Heidelberg, INF 410, D-69120 Heidelberg, Germany. johannes.backs@web.de, Bresch E, Lutz M, Kristen AV, Haass M

المصدر: Cardiovascular research [Cardiovasc Res] 2005 Aug 01; Vol. 67 (2), pp. 283-90.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford Journals Country of Publication: England NLM ID: 0077427 Publication Model: Print Cited Medium: Print ISSN: 0008-6363 (Print) Linking ISSN: 00086363 NLM ISO Abbreviation: Cardiovasc Res Subsets: MEDLINE

مواضيع طبية MeSH: Endothelin-1/*pharmacology , Heart Failure/*metabolism , Myocardium/*metabolism , Norepinephrine/*metabolism, Animals ; Biological Transport ; Carrier Proteins/metabolism ; Endothelin-1/antagonists & inhibitors ; Endothelin-1/metabolism ; Heart Failure/physiopathology ; Male ; Mazindol/metabolism ; Myocardial Contraction ; Neurons/metabolism ; Perfusion ; Phenylpropionates/pharmacology ; Pyrimidines/pharmacology ; Rats ; Rats, Wistar