نتائج البحث - "Marc M. Loriaux"

1

Reversible suppression of T cell function in the bone marrow microenvironment of acute myeloid leukemia

المصدر: Proceedings of the National Academy of Sciences of the United States of America

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15339f906426a6b4a5b79931d6d9a59b
http://europepmc.org/articles/PMC7321988

2

Integrative analysis of drug response and clinical outcome in acute myeloid leukemia

المؤلفون: Daniel Bottomly, Nicola Long, Anna Reister Schultz, Stephen E. Kurtz, Cristina E. Tognon, Kara Johnson, Melissa Abel, Anupriya Agarwal, Sammantha Avaylon, Erik Benton, Aurora Blucher, Uma Borate, Theodore P. Braun, Jordana Brown, Jade Bryant, Russell Burke, Amy Carlos, Bill H. Chang, Hyun Jun Cho, Stephen Christy, Cody Coblentz, Aaron M. Cohen, Amanda d’Almeida, Rachel Cook, Alexey Danilov, Kim-Hien T. Dao, Michie Degnin, James Dibb, Christopher A. Eide, Isabel English, Stuart Hagler, Heath Harrelson, Rachel Henson, Hibery Ho, Sunil K. Joshi, Brian Junio, Andy Kaempf, Yoko Kosaka, Ted Laderas, Matt Lawhead, Hyunjung Lee, Jessica T. Leonard, Chenwei Lin, Evan F. Lind, Selina Qiuying Liu, Pierrette Lo, Marc M. Loriaux, Samuel Luty, Julia E. Maxson, Tara Macey, Jacqueline Martinez, Jessica Minnier, Andrea Monteblanco, Motomi Mori, Quinlan Morrow, Dylan Nelson, Justin Ramsdill, Angela Rofelty, Alexandra Rogers, Kyle A. Romine, Peter Ryabinin, Jennifer N. Saultz, David A. Sampson, Samantha L. Savage, Robert Schuff, Robert Searles, Rebecca L. Smith, Stephen E. Spurgeon, Tyler Sweeney, Ronan T. Swords, Aashis Thapa, Karina Thiel-Klare, Elie Traer, Jake Wagner, Beth Wilmot, Joelle Wolf, Guanming Wu, Amy Yates, Haijiao Zhang, Christopher R. Cogle, Robert H. Collins, Michael W. Deininger, Christopher S. Hourigan, Craig T. Jordan, Tara L. Lin, Micaela E. Martinez, Rachel R. Pallapati, Daniel A. Pollyea, Anthony D. Pomicter, Justin M. Watts, Scott J. Weir, Brian J. Druker, Shannon K. McWeeney, Jeffrey W. Tyner

المصدر: Cancer Cell. 40:850-864.e9

مصطلحات موضوعية: Cohort Studies, Leukemia, Myeloid, Acute, Cancer Research, Oncology, Humans, Cell Differentiation, Receptors, Cell Surface, Transcriptome

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b6098b4d093afd3e38ecac02c438f88
https://doi.org/10.1016/j.ccell.2022.07.002

3

Aurora A kinase as a target for therapy in

المؤلفون: Jessica, Leonard, Joelle Sj, Wolf, Michelle, Degnin, Christopher A, Eide, Dorian, LaTocha, Kyle, Lenz, Beth, Wilmot, Charles G, Mullighan, Mignon, Loh, Stephen P, Hunger, Brian J, Druker, Marc M, Loriaux, Jeffrey W, Tyner, Bill H, Chang

المصدر: Haematologica

مصطلحات موضوعية: Oncogene Proteins, Fusion, Basic Helix-Loop-Helix Transcription Factors, Humans, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Letters to the Editor, Translocation, Genetic, Aurora Kinase A

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::7d71eca58fe90063009add87bec2f14f
https://pubmed.ncbi.nlm.nih.gov/34233449

4

Functional genomic landscape of acute myeloid leukaemia

المؤلفون: Robert H. Collins, Deirdre Devine, Beth Wilmot, Justin Ramsdill, Erik Segerdell, Bruno C. Medeiros, Brian J. Druker, Dylan Nelson, Micaela E. Martinez, Ryan C. Johnson, Robert Schuff, Robert P. Searles, Scott Weir, James Dibb, Elie Traer, Pierrette Lo, Haijiao Zhang, Rachel Henson, Tara A. Macey, Isabel English, Cody Coblentz, Christopher A. Eide, Ceilidh Nichols, Aurora Blucher, Ryan M. Winters, David L. Wiest, Corinne Visser, Michael W. Deininger, Stephen E. Kurtz, Daniel A. Pollyea, Justin M. Watts, Amy S. Carlos, Denise C. Connolly, Andy Kaempf, Angela Rofelty, Samuel B. Luty, Rachel J. Cook, Jill Peters, Kristen Werth, Shannon K. McWeeney, Joseph Carroll, Samantha L. Savage, Ronan T. Swords, Uma Borate, Aashis Thapa, Abdusebur Jemal, Joelle Wolf, Patricia Kropf, Rebecca Smith, Tyler Sweeney, Russell T. Burke, Rachel R. Pallapati, Anna Reister Schultz, Kim Hien T. Dao, Daniel Bottomly, Cristina E. Tognon, Alexey V. Danilov, Jason M. Glover, Jason D. MacManiman, Michie Degnin, Amy Yates, Libbey White, David K. Edwards, Anupriya Agarwal, Christopher R. Cogle, Kevin Watanabe-Smith, Leylah Drusbosky, Nicola Long, Motomi Mori, Christopher S. Hourigan, Tara L. Lin, Chenwei Lin, Jacqueline Martinez, Bill H. Chang, Richie Carpenter, Stephen E. Spurgeon, Brian Junio, Marc M. Loriaux, Craig T. Jordan, Hibery Ho, Selina Qiuying Liu, Melissa L. Abel, Amanda d’Almeida, Jake Wagner, Jade Bryant, Jeffrey W. Tyner, Jessica Leonard, Kara Johnson

المصدر: Nature

مصطلحات موضوعية: Male, 0301 basic medicine, Myeloid, Gene regulatory network, Datasets as Topic, Genomics, Computational biology, Biology, Article, DNA Methyltransferase 3A, Transcriptome, 03 medical and health sciences, 0302 clinical medicine, Proto-Oncogene Proteins, hemic and lymphatic diseases, medicine, Humans, Exome, DNA (Cytosine-5-)-Methyltransferases, Molecular Targeted Therapy, Exome sequencing, Regulation of gene expression, Multidisciplinary, Serine-Arginine Splicing Factors, Genome, Human, Sequence Analysis, RNA, Nuclear Proteins, medicine.disease, Human genetics, 3. Good health, Gene Expression Regulation, Neoplastic, Repressor Proteins, Leukemia, Myeloid, Acute, Leukemia, 030104 developmental biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Core Binding Factor Alpha 2 Subunit, Female, Nucleophosmin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65ec9f74bb9044f4d83aab7c87cd9b94
https://doi.org/10.1038/s41586-018-0623-z

Find this article in full text from Springer Verlag.

Find this article in full text from ProQuest

5

Mast cell sarcoma with concurrent mast cell leukaemia

المؤلفون: Marc M. Loriaux, Ken Gatter, Rita M. Braziel, Guang Fan, Lauren M. Raymond, Philipp W. Raess, Jennifer Dunlap, Tracy Funk

المصدر: British journal of haematologyReferences. 189(4)

مصطلحات موضوعية: Adult, Adolescent, business.industry, Mast cell leukaemia, Mast-Cell Sarcoma, Leukemia, Mast-Cell, Hematology, Middle Aged, medicine.disease, Young Adult, Child, Preschool, Cancer research, Mast cell sarcoma, Medicine, Humans, business, Child, Aged

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b75304f1eed43ca4dc304160f16a91c5
https://pubmed.ncbi.nlm.nih.gov/32242922

View record at Wiley

6

SYK inhibition thwarts the BAFF - B-cell receptor crosstalk and thereby antagonizes Mcl-1 in chronic lymphocytic leukemia

المؤلفون: Claire Godbersen, Bhargava Sreekantham, Olga V. Danilova, Scott R Best, Alexey V. Danilov, Cody Paiva, Prabhjot Kaur, Stephen E. Spurgeon, Marc M. Loriaux, Taylor Rowland

المصدر: Haematologica

مصطلحات موضوعية: 0301 basic medicine, Cell Survival, Chronic lymphocytic leukemia, B-cell receptor, Receptors, Antigen, B-Cell, Syk, CHO Cells, Biology, Models, Biological, Article, 03 medical and health sciences, Cricetulus, immune system diseases, Cell Line, Tumor, hemic and lymphatic diseases, B-Cell Activating Factor, medicine, Animals, Cluster Analysis, Humans, Syk Kinase, Chronic Lymphocytic Leukemia, B-cell activating factor, TNF Receptor-Associated Factor 3, Gene Expression Profiling, NF-kappa B, Hematology, TNF Receptor-Associated Factor 2, medicine.disease, Immunohistochemistry, Leukemia, Lymphocytic, Chronic, B-Cell, Cell biology, Leukemia, Crosstalk (biology), 030104 developmental biology, Proto-Oncogene Proteins c-bcl-2, Cancer research, Myeloid Cell Leukemia Sequence 1 Protein, Signal transduction, Immunoglobulin Heavy Chains, Protein Binding, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a841e2e303a0a930f0398030f14d15f
https://doi.org/10.3324/haematol.2017.170571

7

Double autophagy stimulation using chemotherapy and mTOR inhibition combined with hydroxychloroquine for autophagy modulation in patients with relapsed or refractory multiple myeloma

المؤلفون: Stephen E. Spurgeon, James Gajewski, Edward A. Stadtmauer, Marc M. Loriaux, Emma C. Scott, Ravi K. Amaravadi, Miranda Gordon, George Thomas, Jennifer Botelho, Jennifer Podolak, Eva Medvedova, Richard T. Maziarz, Michael J. Cascio, Shara Reasor-Heard, Anne Kratz, Dan T. Vogl, Byung Park

المصدر: Haematologica. 102:e261-e265

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52c8b7e55f26d75c19575c21d9fd7f74
https://doi.org/10.3324/haematol.2016.162321

8

The Colony-Stimulating Factor 3 Receptor T640N Mutation Is Oncogenic, Sensitive to JAK Inhibition, and Mimics T618I

المؤلفون: Jason D. MacManiman, Jason Gotlib, Emily A. Stevens, Peter L. Greenberg, Melissa L. Abel, Samuel B. Luty, Marc M. Loriaux, Jason C. Paik, Swaleh Bahamadi, Jeffrey W. Tyner, Julia E. Maxson, Christopher A. Eide, Samantha L. Savage

المصدر: Clinical Cancer Research. 22:757-764

مصطلحات موضوعية: Male, 0301 basic medicine, Cancer Research, Glycosylation, DNA Mutational Analysis, Chronic neutrophilic leukemia, Mutant, Biology, Ligands, medicine.disease_cause, Article, Cell Line, Mice, 03 medical and health sciences, Bone Marrow, Receptors, Colony-Stimulating Factor, medicine, Animals, Humans, Codon, Protein Kinase Inhibitors, Bone Marrow Transplantation, Janus Kinases, Mutation, Leukemia, Point mutation, Middle Aged, medicine.disease, Molecular biology, Disease Models, Animal, Cell Transformation, Neoplastic, 030104 developmental biology, medicine.anatomical_structure, Amino Acid Substitution, Oncology, Atypical chronic myeloid leukemia, Female, Bone marrow, Janus kinase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a0f2116441cfd4006dc1506ba5d3860
https://doi.org/10.1158/1078-0432.ccr-14-3100

9

Integrated Proteogenomic Characterization of Clear Cell Renal Cell Carcinoma

المؤلفون: David J. Clark, Jianbo Pan, Gerald W. Hart, Katherine A. Hoadley, Negin Vatanian, Shuang Cai, Yige Wu, Felipe da Veiga Leprevost, A. Ari Hakimi, Sanford P. Markey, Thomas F. Westbrook, Maciej Wiznerowicz, Nathan Edwards, Alla Y. Karpova, Sohini Sengupta, Marcin Cieslik, Samuel H. Payne, Xi Steven Chen, Guo Ci Teo, Jin Chen, Boris Reva, Corbin D. Jones, Michael J. Birrer, Ying Wang, Kelly V. Ruggles, Doug W. Chan, John McGee, Marcin J. Domagalski, Song Cao, Linda Hannick, Christopher R. Kinsinger, David I. Heiman, Jennifer M. Eschbacher, Munziba Khan, Jason E. McDermott, Dmitry M. Avtonomov, Sue Hilsenbeck, Qing Kay Li, Jiayi Ji, Emek Demir, Rebecca I. Montgomery, Qingsong Gao, Beom-Jun Kim, Xiaoyu Song, Karl R. Clauser, Christian P. Pavlovich, Richard D. Smith, Maureen Dyer, Jeffrey W. Tyner, Amy M. Perou, Yuping Zhang, Dana R. Valley, George D. Wilson, Shiyong Ma, Minghui Ao, Jiang Qian, Umut Ozbek, Melissa Borucki, Zhi Li, Michael Schnaubelt, Chen Huang, Piotr A. Mieczkowski, Francesca Petralia, Abdul Samad Hashimi, Hui Yin Chang, Liang-Bo Wang, Matthew E. Monroe, Peter B. McGarvey, Tao Liu, Karen A. Ketchum, Hui Zhang, Bing Zhang, D. R. Mani, Houston Culpepper, Hua Zhou, Saravana M. Dhanasekaran, Paul D. Piehowski, Zhidong Tu, Brian J. Druker, Ki Sung Um, Zhiao Shi, Uma Borate, Uma Velvulou, Michael Ittmann, Weiping Ma, Steven M. Foltz, Heng Zhu, Stacey Gabriel, Hongwei Liu, Ramani B. Kothadia, Lin Chen, Ewa P. Malc, Marina A. Gritsenko, Jun Zhu, David Chesla, Lori J. Sokoll, Stephen E. Stein, Andrzej Antczak, Matthew L. Anderson, Alyssa Charamut, Pamela Grady, Michael T. Lewis, Shannon Richey, Tanya Krubit, Alexander R. Pico, Kyung-Cho Cho, Daniel C. Rohrer, Francesmary Modugno, Stephanie De Young, Li Ding, Michael Smith, Mathangi Thiagarajan, Alexey I. Nesvizhskii, Shrabanti Chowdhury, Noam D. Beckmann, Kimberly R. Holloway, Ratna R. Thangudu, Sherri R. Davies, Tung-Shing M. Lih, Nicole Tignor, Anna Calinawan, Meghan C. Burke, Karna Robinson, Chet Birger, Shalin Patel, Antonio Colaprico, Sarah Keegan, Daniel J. Geiszler, Scott D. Jewell, William Bocik, Snehal Patil, Pei Wang, MacIntosh Cornwell, Emily Kawaler, Seungyeul Yoo, Jasmine Huang, Vladislav A. Petyuk, Ross Bremner, Donghui Tan, Stefani N. Thomas, Emily S. Boja, Anna Malovannaya, Xi Chen, Wenke Liu, Eric E. Schadt, Shankha Satpathy, Nancy Roche, Rajiv Dhir, Cristina E. Tognon, Michelle Chaikin, Gabriel Bromiński, Daniel C. Zhou, Yifat Geffen, Tara Skelly, Jacob J. Day, Sunantha Sethuraman, Sonya Carter, Zhen Zhang, Selim Kalayci, Michael Vernon, Zeynep H. Gümüş, Kai Li, Barbara Hindenach, Matthew J. Ellis, Meenakshi Anurag, David C. Wheeler, Sailaja Mareedu, Andy T. Kong, Arul M. Chinnaiyan, Robert Zelt, Annette Marrero-Oliveras, Henry Rodriguez, James Suh, Anupriya Agarwal, David Fenyö, Galen Hostetter, Liqun Qi, Matthew A. Wyczalkowski, W. Marston Linehan, Tara Hiltke, Feng Chen, Lijun Chen, Jan Lubinski, Chelsea J. Newton, Steven A. Carr, Tatiana Omelchenko, Gilbert S. Omenn, Karsten Krug, Ana I. Robles, Azra Krek, Runyu Hong, Milan G. Chheda, Yize Li, Yan Shi, Lili Blumenberg, Ruiyang Liu, Karin D. Rodland, Hua Sun, Kim Elburn, Jeffrey R. Whiteaker, Christopher J. Ricketts, Gaddy Getz, Daniel W. Chan, Bo Wen, Robert Edwards, Patricia Castro, Yingwei Hu, Pushpa Hariharan, Simina M. Boca, Darlene Tansil, Phillip M. Pierorazio, Yosef E. Maruvka, Sandra Cottingham, James J. Hsieh, Amanda G. Paulovich, Barbara Pruetz, Michael A. Gillette, Yihao Lu, Dmitry Rykunov, Mehdi Mesri, Marc M. Loriaux, Reyka G Jayasinghe, Suhas Vasaikar

المصدر: Cell

مصطلحات موضوعية: Adult, Male, Cell, Computational biology, Biology, Proteomics, Disease-Free Survival, Oxidative Phosphorylation, Article, General Biochemistry, Genetics and Molecular Biology, Transcriptome, 03 medical and health sciences, 0302 clinical medicine, Exome Sequencing, medicine, Biomarkers, Tumor, Tumor Microenvironment, Humans, Exome, Phosphorylation, Carcinoma, Renal Cell, 030304 developmental biology, Epigenomics, Aged, Proteogenomics, Aged, 80 and over, 0303 health sciences, Tumor microenvironment, Genome, Human, Phosphoproteomics, Middle Aged, medicine.disease, Neoplasm Proteins, Gene Expression Regulation, Neoplastic, Clear cell renal cell carcinoma, medicine.anatomical_structure, Female, 030217 neurology & neurosurgery, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7b0db3ed2c470e7d44e149915509d50
https://doi.org/10.1016/j.cell.2019.12.026

10

Synthetic lethality of TNK2 inhibition in PTPN11-mutant leukemia

المؤلفون: Eneida R. Nemecek, Beth Wilmot, Samuel B. Luty, Jeffrey W. Tyner, Christopher A. Eide, Julia E. Maxson, Melissa L. Abel, Daniel Bottomly, Chelsea Jenkins, Marc M. Loriaux, Bill H. Chang, Shannon K. McWeeney, Corinne Togiai

المصدر: Science Signaling. 11

مصطلحات موضوعية: Male, musculoskeletal diseases, 0301 basic medicine, congenital, hereditary, and neonatal diseases and abnormalities, Dasatinib, Protein Tyrosine Phosphatase, Non-Receptor Type 11, Protein tyrosine phosphatase, Biochemistry, Article, Mice, 03 medical and health sciences, hemic and lymphatic diseases, medicine, Animals, Humans, Child, skin and connective tissue diseases, Protein kinase A, Protein Kinase Inhibitors, Molecular Biology, Tumor Stem Cell Assay, Juvenile myelomonocytic leukemia, Chemistry, Myeloid leukemia, Cell Biology, Protein-Tyrosine Kinases, Prognosis, medicine.disease, Survival Rate, Leukemia, Myeloid, Acute, Leukemia, 030104 developmental biology, Leukemia, Myelomonocytic, Juvenile, Cancer research, Phosphorylation, Signal transduction, Synthetic Lethal Mutations, Signal Transduction, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d49e14961db54376fdbe3d1364641900
https://doi.org/10.1126/scisignal.aao5617

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