المؤلفون: Kentaro Watanabe, Shunsuke Kimura, Masafumi Seki, Tomoya Isobe, Yasuo Kubota, Masahiro Sekiguchi, Aiko Sato-Otsubo, Mitsuteru Hiwatari, Motohiro Kato, Akira Oka, Katsuyoshi Koh, Yusuke Sato, Hiroko Tanaka, Satoru Miyano, Tomoko Kawai, Kenichiro Hata, Hiroo Ueno, Yasuhito Nannya, Hiromichi Suzuki, Kenichi Yoshida, Yoichi Fujii, Genta Nagae, Hiroyuki Aburatani, Seishi Ogawa, Junko Takita

المصدر: Oncogene. 41(46):4994-5007

مصطلحات موضوعية: Cancer Research, N-Myc Proto-Oncogene Protein, DNA methylation, Arginine, Cancer metabolism, Gene Expression Regulation, Neoplastic, Paediatric cancer, Neuroblastoma, Mechanisms of disease, Targeted therapies, Cell Line, Tumor, Genetics, Serine, Humans, Molecular Biology, Cell Proliferation

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fc460f50d7e042a1e0d2cf1c462f94c
http://hdl.handle.net/2433/277224

المؤلفون: Seishi Ogawa, Katsuyoshi Koh, Kenichi Chiba, Yuki Arakawa, Tomoya Isobe, Satoru Miyano, Shimon Sakaguchi, Satoshi Saida, Hiroko Tanaka, Hirohito Kubota, Ai Okada, Junko Takita, Koichi Oshima, Yuichi Shiraishi, James B. Wing, Katsutsugu Umeda, Keiko Iwaisako, Hidefumi Hiramatsu, Keiji Tasaka, Hiroo Ueno, Mitsuteru Hiwatari, Souichi Adachi, Itaru Kato, Kuniaki Tanaka, Takashi Mikami

المصدر: Cancer Science

مصطلحات موضوعية: Male, regulatory T cell, Cancer Research, Adolescent, Regulatory T cell, medicine.medical_treatment, immune response, Th1, Young Adult, Basic and Clinical Immunology, Immune system, Immunophenotyping, Cancer immunotherapy, Bone Marrow, Precursor B-Cell Lymphoblastic Leukemia-Lymphoma, hemic and lymphatic diseases, B cell leukemia, Biomarkers, Tumor, Tumor Microenvironment, medicine, Humans, Child, B cell, relapse, Sequence Analysis, RNA, business.industry, Gene Expression Profiling, Infant, Original Articles, General Medicine, biochemical phenomena, metabolism, and nutrition, Flow Cytometry, medicine.disease, Up-Regulation, Gene Expression Regulation, Neoplastic, Leukemia, medicine.anatomical_structure, Oncology, Child, Preschool, B-cell leukemia, Cancer research, bacteria, Original Article, Female, Bone marrow, Neoplasm Recurrence, Local, Single-Cell Analysis, business

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2023e3536c545a4d7b900a5dcc65ce5c
https://doi.org/10.1111/cas.15186

المؤلفون: Satoru Miyano, Keisuke Kataoka, Seishi Ogawa, Yukichi Tanaka, Yuichi Shiraishi, Kenichi Yoshida, Hiromichi Suzuki, Junko Takita, Hiroko Tanaka, Masahiro Sekiguchi, Mitsuteru Hiwatari, Tomoya Isobe, Shunsuke Kimura, Aiko Sato-Otsubo, Yasuo Kubota, Kenichi Chiba, Yoichi Fujii, Kenichiro Hata, Masafumi Seki, Yasuhide Hayashi, Kentaro Watanabe, Tomoko Kawai, Misa Yoshida, Akira Oka

المصدر: Communications Biology, Vol 3, Iss 1, Pp 1-11 (2020)
Communications Biology

مصطلحات موضوعية: Male, 0301 basic medicine, DNA Copy Number Variations, Medicine (miscellaneous), Biology, Polymorphism, Single Nucleotide, Genetic analysis, Article, General Biochemistry, Genetics and Molecular Biology, Paediatric cancer, 03 medical and health sciences, 0302 clinical medicine, Downregulation and upregulation, Carcinoma, Embryonal, Exome Sequencing, Cancer genomics, medicine, Humans, Child, Gene, lcsh:QH301-705.5, Oligonucleotide Array Sequence Analysis, GATA6, Germinoma, Endodermal Sinus Tumor, Teratoma, Infant, Germ cell tumours, DNA Methylation, Neoplasms, Germ Cell and Embryonal, medicine.disease, 030104 developmental biology, lcsh:Biology (General), Child, Preschool, 030220 oncology & carcinogenesis, embryonic structures, DNA methylation, Cancer research, Female, FOXA2, Germ cell tumors, General Agricultural and Biological Sciences

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ce599b5514765362179c01db60a3e86
http://link.springer.com/article/10.1038/s42003-020-01267-8

المؤلفون: Tomoya Isobe, Masatoshi Takagi, Aiko Sato-Otsubo, Akira Nishimura, Genta Nagae, Chika Yamagishi, Moe Tamura, Yosuke Tanaka, Shuhei Asada, Reina Takeda, Akiho Tsuchiya, Xiaonan Wang, Kenichi Yoshida, Yasuhito Nannya, Hiroo Ueno, Ryo Akazawa, Itaru Kato, Takashi Mikami, Kentaro Watanabe, Masahiro Sekiguchi, Masafumi Seki, Shunsuke Kimura, Mitsuteru Hiwatari, Motohiro Kato, Shiro Fukuda, Kenji Tatsuno, Shuichi Tsutsumi, Akinori Kanai, Toshiya Inaba, Yusuke Shiozawa, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Rishi S. Kotecha, Mark N. Cruickshank, Fumihiko Ishikawa, Tomohiro Morio, Mariko Eguchi, Takao Deguchi, Nobutaka Kiyokawa, Yuki Arakawa, Katsuyoshi Koh, Yuki Aoki, Takashi Ishihara, Daisuke Tomizawa, Takako Miyamura, Eiichi Ishii, Shuki Mizutani, Nicola K. Wilson, Berthold Göttgens, Satoru Miyano, Toshio Kitamura, Susumu Goyama, Akihiko Yokoyama, Hiroyuki Aburatani, Seishi Ogawa, Junko Takita

المساهمون: Isobe, Tomoya [0000-0002-3487-3307], Takagi, Masatoshi [0000-0002-7580-9184], Nishimura, Akira [0000-0002-9127-807X], Nagae, Genta [0000-0002-2929-7990], Tanaka, Yosuke [0000-0002-8538-0916], Asada, Shuhei [0000-0001-6116-7996], Takeda, Reina [0000-0002-4233-8806], Yoshida, Kenichi [0000-0003-4612-2778], Ueno, Hiroo [0000-0001-7617-1672], Akazawa, Ryo [0000-0002-8770-0493], Kato, Itaru [0000-0002-2932-4960], Mikami, Takashi [0000-0003-1846-4500], Sekiguchi, Masahiro [0000-0002-7941-9319], Seki, Masafumi [0000-0003-4671-7026], Fukuda, Shiro [0000-0002-0065-662X], Tatsuno, Kenji [0000-0002-3046-3941], Kanai, Akinori [0000-0003-1555-6768], Shiozawa, Yusuke [0000-0001-8673-677X], Tanaka, Hiroko [0000-0001-9634-8922], Kotecha, Rishi S [0000-0003-1836-4075], Cruickshank, Mark N [0000-0002-1869-1175], Ishikawa, Fumihiko [0000-0002-8717-1237], Morio, Tomohiro [0000-0002-9259-1025], Eguchi, Mariko [0000-0001-8727-1732], Deguchi, Takao [0000-0001-9932-4299], Kiyokawa, Nobutaka [0000-0001-9310-2126], Ishihara, Takashi [0000-0003-1061-085X], Tomizawa, Daisuke [0000-0003-1520-7007], Miyamura, Takako [0000-0002-3226-556X], Wilson, Nicola K [0000-0003-0865-7333], Göttgens, Berthold [0000-0001-6302-5705], Kitamura, Toshio [0000-0001-7855-1767], Goyama, Susumu [0000-0002-9339-1826], Aburatani, Hiroyuki [0000-0003-0438-1544], Ogawa, Seishi [0000-0002-7778-5374], Takita, Junko [0000-0002-2452-6520], Apollo - University of Cambridge Repository

المصدر: Nature Communications. 13

مصطلحات موضوعية: Multidisciplinary, Acute lymphocytic leukaemia, 45/61, 692/4028/67/1990/283/2125, article, General Physics and Astronomy, Infant, 45/23, 631/67/69, General Chemistry, Histone-Lysine N-Methyltransferase, Precursor Cell Lymphoblastic Leukemia-Lymphoma, 45/15, 631/208/212/2166, Personalized medicine, General Biochemistry, Genetics and Molecular Biology, 38/91, Paediatric cancer, 692/4028/67/2332, Cancer genomics, Humans, Gene Fusion, Myeloid-Lymphoid Leukemia Protein, Transcription Factors

وصف الملف: application/pdf; application/zip; text/xml

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4efe6ef437b83043af5d9ad9ed8581c0
http://hdl.handle.net/2433/276078

المؤلفون: Tsutomu Toki, Yasuhide Hayashi, Jiro Kagawa, Masafumi Seki, Kenichi Yoshida, Yuichi Shiraishi, Tomoko Kawai, Kenichiro Hata, Nobutaka Kiyokawa, Kenichi Chiba, Satoru Miyano, Junko Takita, Hiroko Tanaka, Tadayuki Kumagai, Hiromichi Suzuki, Tatsuya Ito, Yasuo Kubota, Keisuke Kataoka, Kiminori Terui, Etsuro Ito, Akira Oka, Tomoya Isobe, Kentaro Ohki, Seishi Ogawa, Kumiko Uryu, Atsushi Sato

المصدر: Cancer Science

مصطلحات موضوعية: Male, 0301 basic medicine, Cancer Research, Down syndrome, Lineage (genetic), Chromosomes, Human, Pair 21, Population, acute lymphoblastic leukemia, genetic analysis, Biology, Genetic analysis, Epigenesis, Genetic, 03 medical and health sciences, 0302 clinical medicine, children, medicine, Humans, Genetic Predisposition to Disease, Philadelphia Chromosome, Epigenetics, Child, Promoter Regions, Genetic, education, Genetics, Genomics, and Proteomics, Gene, Genetics, education.field_of_study, Sequence Analysis, RNA, Gene Expression Profiling, High-Throughput Nucleotide Sequencing, Cell Differentiation, Sequence Analysis, DNA, Original Articles, General Medicine, DNA Methylation, Precursor Cell Lymphoblastic Leukemia-Lymphoma, medicine.disease, Gene Expression Regulation, Neoplastic, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, Core Binding Factor Alpha 2 Subunit, DNA methylation, Female, Original Article, Chromosome 21, epigenetic analysis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e09a6ea05f36254ce7cfcc60af71bf18
https://doi.org/10.1111/cas.14160

المؤلفون: Yasuhide Hayashi, Seishi Ogawa, Satoru Miyano, Akira Oka, Masahiro Sekiguchi, Noriko Hoshino, Hiromichi Suzuki, Mitsuteru Hiwatarai, Kenichi Yoshida, Tomoya Isobe, Kentaro Watanabe, Yusuke Shiozawa, Shunsuke Kimura, Masafumi Seki, Junko Takita

المصدر: PLoS ONE
PLoS ONE, Vol 16, Iss 1, p e0245526 (2021)

مصطلحات موضوعية: Molecular biology, Cellular differentiation, Gene Dosage, Gene Expression, Biochemistry, Transcriptome, Neuroblastoma, Sequencing techniques, Gene expression, Adrenal Glands, Basic Cancer Research, Medicine and Health Sciences, Cluster Analysis, Amino Acids, Multidisciplinary, Organic Compounds, Cell Differentiation, RNA sequencing, Genomics, Chemistry, Oncology, Physical Sciences, Medicine, Anatomy, Research Article, Proline, Blastoma, Science, Endocrine System, Biology, Gene dosage, Human Genomics, Cancer Genomics, Genomic Medicine, medicine, Genetics, Humans, Genetic Predisposition to Disease, ATRX, Cell growth, Gene Expression Profiling, Organic Chemistry, Chemical Compounds, Cancers and Neoplasms, Biology and Life Sciences, Proteins, Cyclic Amino Acids, medicine.disease, Gene expression profiling, Research and analysis methods, Molecular biology techniques, Mutation, Cancer research, Developmental Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7885a6fd0cc7715b1ae6d86f7355564
https://pubmed.ncbi.nlm.nih.gov/33465163

المؤلفون: Sadao Tokimasa, Dai Nishijima, Junko Takita, Hiroko Tanaka, Masahiro Nakagawa, Kentaro Ohki, Nobuyuki Kakiuchi, Masashi Sanada, Seishi Ogawa, Hiroo Ueno, Koji Kato, Yasuhito Nannya, Takao Deguchi, Junichi Hara, Shunsuke Kimura, Yuichi Shiraishi, Hiroyuki Takahashi, Tetsuichi Yoshizato, Takeshi Inukai, Keizo Horibe, Yoshiko Hashii, Nobutaka Kiyokawa, Atsushi Sato, Hideki Makishima, Atsushi Manabe, Yusuke Shiozawa, Yoshiyuki Kosaka, Masafumi Seki, Tomoya Isobe, Satoru Miyano, Yuka Iijima-Yamashita, Keisuke Kataoka, Kenichi Yoshida, Toshihiko Imamura, Kenichi Chiba

المصدر: Blood Adv

مصطلحات موضوعية: 0301 basic medicine, Oncology, medicine.medical_specialty, Lymphoblastic Leukemia, Disease, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Gene expression, medicine, Humans, Child, Gene, B cell, B-Lymphocytes, Lymphoid Neoplasia, business.industry, Cancer, High-Throughput Nucleotide Sequencing, Hematology, Precursor Cell Lymphoblastic Leukemia-Lymphoma, medicine.disease, Prognosis, Reverse transcription polymerase chain reaction, 030104 developmental biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Cohort, Mutation, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58383aec0ed0c3ad22a69902ef8fe41c
https://pubmed.ncbi.nlm.nih.gov/33095873

المؤلفون: Matthias Schwab, Cesar R. Najera, Kjeld Schmiegelow, Zhiwei Chen, Cynthia Jeffries, Ching-Hon Pui, Mary V. Relling, Tomoya Isobe, Deepa Bhojwani, Allen Eng Juh Yeoh, Takaya Moriyama, Hiroki Hori, Atsushi Manabe, Keito Hoshitsuki, Yan Lu, Rina Nishii, Kentaro Kihira, Federico Antillon Klussmann, Robert McCorkle, Wenjian Yang, Jun J. Yang, Virginia Perez-Andreu, Hiroto Inaba, Katsuyoshi Koh, Lie Li, Shirley Kow-Yin Kham, Yoshihiro Komada, Xujie Zhao, Ting-Nien Lin, Motohiro Kato, Edwynn Kean Hui Chiew, Jacob Nersting, Ute Hofmann, William E. Evans

المصدر: Nature Genetics. 48:367-373

مصطلحات موضوعية: 0301 basic medicine, Antimetabolites, Antineoplastic, Thiopurine methyltransferase, Mercaptopurine, Mechanism (biology), Metabolism, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Biology, Pharmacology, Polymorphism, Single Nucleotide, Article, Hematopoiesis, 03 medical and health sciences, Haematopoiesis, 030104 developmental biology, 0302 clinical medicine, 030220 oncology & carcinogenesis, Toxicity, Genetics, biology.protein, Humans, Pyrophosphatases, Genetic Association Studies

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbbccfafb3316d53a99c0cbb7a96a3ae
https://doi.org/10.1038/ng.3508

المؤلفون: Yukichi Tanaka, Tomoya Isobe, Motohiro Kato, Hajime Hosoi, Yoshikage Inoue, Kenichiro Hata, Takao Deguchi, Chikako Kiyotani, Masafumi Seki, Hiromichi Suzuki, Tsuyoshi Ito, Akihiro Iguchi, Yuichi Shiraishi, Tomoko Iehara, Satoru Miyano, Yusuke Sato, Yusuke Shiozawa, Junko Takita, Hiroko Tanaka, Akira Yokoyama, Masahiro Sekiguchi, Shunsuke Kimura, Keisuke Kataoka, Akiko Inoue, Asahito Hama, Teppei Shimamura, Junya Fujimura, Tomoaki Taguchi, Tomoko Kawai, Misa Yoshida, Masaharu Akiyama, Akira Oka, Nobuyuki Kakiuchi, Masashi Sanada, Kenichi Chiba, Kenichi Yoshida, Seishi Ogawa

المصدر: Cancer research. 78(4)

مصطلحات موضوعية: 0301 basic medicine, Male, Cancer Research, Gene Expression Profiling, Wnt signaling pathway, Pancreatoblastoma, LGR5, Biology, medicine.disease, Pediatric cancer, Loss of heterozygosity, Transcriptome, Pancreatic Neoplasms, 03 medical and health sciences, 030104 developmental biology, medicine.anatomical_structure, Oncology, medicine, Cancer research, Humans, Exome, Female, Allele, Pancreas, Child

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61a83bb232a1c95f78c74a28912c43d1
https://pubmed.ncbi.nlm.nih.gov/29233928

المؤلفون: Motohiro Kato, Takao Deguchi, Atsushi Manabe, Yoshiko Hashii, Atsushi Iwama, Yoichi Fujii, Kenichi Yoshida, Katsuyoshi Koh, Masaharu Akiyama, Akira Ohara, Masafumi Seki, Kenichi Chiba, Yasuhide Hayashi, Ryoji Kobayashi, Keizo Horibe, Masashi Sanada, Akira Oka, Changshan Wang, Ayana Kon, Seishi Ogawa, Hiroyuki Mano, Kentaro Ohki, Kyoko Masuda, Shunsuke Kimura, Satoru Miyano, Lin Lin, Hiroo Ueno, Hiromichi Suzuki, Hiroshi Moritake, Hiroshi Kawamoto, Nobutaka Kiyokawa, Yaeko Nakajima-Takagi, Junko Takita, Hiroko Tanaka, Yuki Arakawa, Ryoji Hanada, Yuichi Shiraishi, Masatoshi Takagi, Teppei Shimamura, Atsushi Sato, Yusuke Shiozawa, Keisuke Kataoka, Toshihiko Imamura, Tomoya Isobe

المصدر: Nature genetics. 49(8)

مصطلحات موضوعية: 0301 basic medicine, Male, Adolescent, T cell, Biology, Transcriptome, Fusion gene, 03 medical and health sciences, T-Lymphocyte Subsets, Proto-Oncogene Proteins, Genetics, medicine, Humans, Genetic Predisposition to Disease, Progenitor cell, Child, Cell growth, Gene Expression Profiling, Infant, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Fusion protein, Survival Analysis, Gene expression profiling, 030104 developmental biology, medicine.anatomical_structure, Child, Preschool, Cancer research, Trans-Activators, Female, Gene Fusion, CD8

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae31baf4ee8b231eddac4657cf55bc53
https://pubmed.ncbi.nlm.nih.gov/28671687