المؤلفون: Awasthi P; Institute of Bioorganic Chemistry, Polish Academy of Sciences, Zygmunta Noskowskiego 12/14, 61-704, Poznań, Poland., Mishra AK; Khalifa Centre for Genetic Engineering and Biotechnology, United Arab Emirates University, P.O. Box. Al Ain 15551, United Arab Emirates. Electronic address: ajaymishra24@uaeu.ac.ae., Kocábek T; Biology Centre, Czech Academy of Sciences, Institute of Plant Molecular Biology, Branišovská 31, 370 05, České Budějovice, Czech Republic., Nath VS; Khalifa Centre for Genetic Engineering and Biotechnology, United Arab Emirates University, P.O. Box. Al Ain 15551, United Arab Emirates., Mishra S; Khalifa Centre for Genetic Engineering and Biotechnology, United Arab Emirates University, P.O. Box. Al Ain 15551, United Arab Emirates., Hazzouri KM; Khalifa Centre for Genetic Engineering and Biotechnology, United Arab Emirates University, P.O. Box. Al Ain 15551, United Arab Emirates., Sudalaimuthuasari N; Khalifa Centre for Genetic Engineering and Biotechnology, United Arab Emirates University, P.O. Box. Al Ain 15551, United Arab Emirates., Stajner N; Department of Agronomy, Biotechnical Faculty, University of Ljubljana, 1000, Ljubljana, Slovenia., Jakše J; Department of Agronomy, Biotechnical Faculty, University of Ljubljana, 1000, Ljubljana, Slovenia., Krofta K; Hop Research Institute, Co. Ltd., Kadaňská 2525, 438 46, Žatec, Czech Republic., Hájek T; University of South Bohemia, Faculty of Science, Branišovská 1716/31c, 370 05, České Budějovice, Czech Republic., Amiri KM; Khalifa Centre for Genetic Engineering and Biotechnology, United Arab Emirates University, P.O. Box. Al Ain 15551, United Arab Emirates. Electronic address: k.amiri@uaeu.ac.ae.

المصدر: Plant physiology and biochemistry : PPB [Plant Physiol Biochem] 2023 Aug; Vol. 201, pp. 107851. Date of Electronic Publication: 2023 Jun 19.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Country of Publication: France NLM ID: 9882449 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2690 (Electronic) Linking ISSN: 09819428 NLM ISO Abbreviation: Plant Physiol Biochem Subsets: MEDLINE

مواضيع طبية MeSH: Humulus*/genetics, CRISPR-Cas Systems ; Gene Expression Profiling ; Transcriptome ; Genomics

المؤلفون: Mishra AK; Khalifa Centre for Genetic Engineering and Biotechnology, United Arab Emirates University, Al Ain, 15551, United Arab Emirates., Kocábek T; Biology Centre, Czech Academy of Sciences, Institute of Plant Molecular Biology, Branišovská 31, 370 05, České Budějovice, Czech Republic. Electronic address: kocabek@umbr.cas.cz., Nath VS; Khalifa Centre for Genetic Engineering and Biotechnology, United Arab Emirates University, Al Ain, 15551, United Arab Emirates., Khan A; Biology Centre, Czech Academy of Sciences, Institute of Plant Molecular Biology, Branišovská 31, 370 05, České Budějovice, Czech Republic., Matoušek J; Biology Centre, Czech Academy of Sciences, Institute of Plant Molecular Biology, Branišovská 31, 370 05, České Budějovice, Czech Republic., Hazzouri KM; Khalifa Centre for Genetic Engineering and Biotechnology, United Arab Emirates University, Al Ain, 15551, United Arab Emirates., Sudalaimuthuasari N; Khalifa Centre for Genetic Engineering and Biotechnology, United Arab Emirates University, Al Ain, 15551, United Arab Emirates., Krofta K; Hop Research Institute, Co. Ltd, Kadaňská 2525, 438 46, Žatec, Czech Republic., Ludwig-Müller J; Institute of Botany, Technical University Dresden, Dresden, Germany., Amiri KMA; Khalifa Centre for Genetic Engineering and Biotechnology, United Arab Emirates University, Al Ain, 15551, United Arab Emirates. Electronic address: k.amiri@uaeu.ac.ae.

المصدر: Plant physiology and biochemistry : PPB [Plant Physiol Biochem] 2023 Apr; Vol. 197, pp. 107636. Date of Electronic Publication: 2023 Mar 10.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Country of Publication: France NLM ID: 9882449 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2690 (Electronic) Linking ISSN: 09819428 NLM ISO Abbreviation: Plant Physiol Biochem Subsets: MEDLINE

مواضيع طبية MeSH: Humulus*/genetics , Arabidopsis*/genetics , Arabidopsis*/metabolism, Transcription Factors/metabolism ; Flavonoids/metabolism ; Plant Proteins/metabolism ; Gene Expression Regulation, Plant

المؤلفون: Nath VS; Biology Centre, Czech Academy of Sciences, Institute of Plant Molecular Biology, Branišovská 31, 37005 České Budějovice, Czech Republic., Mishra AK; Biology Centre, Czech Academy of Sciences, Institute of Plant Molecular Biology, Branišovská 31, 37005 České Budějovice, Czech Republic. Electronic address: ajaymishra24@umbr.cas.cz., Awasthi P; Biology Centre, Czech Academy of Sciences, Institute of Plant Molecular Biology, Branišovská 31, 37005 České Budějovice, Czech Republic., Shrestha A; Biology Centre, Czech Academy of Sciences, Institute of Plant Molecular Biology, Branišovská 31, 37005 České Budějovice, Czech Republic., Matoušek J; Biology Centre, Czech Academy of Sciences, Institute of Plant Molecular Biology, Branišovská 31, 37005 České Budějovice, Czech Republic., Jakse J; Department of Agronomy, Biotechnical Faculty, University of Ljubljana, Jamnikarjeva 101, SI-1000 Ljubljana, Slovenia., Kocábek T; Biology Centre, Czech Academy of Sciences, Institute of Plant Molecular Biology, Branišovská 31, 37005 České Budějovice, Czech Republic., Khan A; Biology Centre, Czech Academy of Sciences, Institute of Plant Molecular Biology, Branišovská 31, 37005 České Budějovice, Czech Republic.

المصدر: Genomics [Genomics] 2021 Jul; Vol. 113 (4), pp. 2350-2364. Date of Electronic Publication: 2021 May 27.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Academic Press Country of Publication: United States NLM ID: 8800135 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1089-8646 (Electronic) Linking ISSN: 08887543 NLM ISO Abbreviation: Genomics Subsets: MEDLINE

مواضيع طبية MeSH: Citrus*/genetics , Humulus*/genetics , RNA, Long Noncoding*/genetics , Viroids*/genetics, Gene Expression Profiling ; Plant Bark ; Plant Diseases/genetics

المؤلفون: Awasthi P; Biology Centre, Czech Academy of Sciences, Institute of Plant Molecular Biology, Branišovská 31, 370 05, České Budějovice, Czech Republic., Kocábek T; Biology Centre, Czech Academy of Sciences, Institute of Plant Molecular Biology, Branišovská 31, 370 05, České Budějovice, Czech Republic., Mishra AK; Biology Centre, Czech Academy of Sciences, Institute of Plant Molecular Biology, Branišovská 31, 370 05, České Budějovice, Czech Republic. Electronic address: ajaymishra24@umbr.cas.cz., Nath VS; Biology Centre, Czech Academy of Sciences, Institute of Plant Molecular Biology, Branišovská 31, 370 05, České Budějovice, Czech Republic., Shrestha A; Biology Centre, Czech Academy of Sciences, Institute of Plant Molecular Biology, Branišovská 31, 370 05, České Budějovice, Czech Republic., Matoušek J; Biology Centre, Czech Academy of Sciences, Institute of Plant Molecular Biology, Branišovská 31, 370 05, České Budějovice, Czech Republic.

المصدر: Plant physiology and biochemistry : PPB [Plant Physiol Biochem] 2021 Mar; Vol. 160, pp. 1-7. Date of Electronic Publication: 2021 Jan 07.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Country of Publication: France NLM ID: 9882449 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2690 (Electronic) Linking ISSN: 09819428 NLM ISO Abbreviation: Plant Physiol Biochem Subsets: MEDLINE

مواضيع طبية MeSH: CRISPR-Cas Systems*, Humulus/*genetics , Oxidoreductases/*genetics, Agrobacterium tumefaciens ; Chlorophyll ; Chlorophyll A ; Gene Editing ; Genome, Plant/genetics ; Humulus/enzymology ; Mutagenesis ; Plants, Genetically Modified/genetics ; RNA, Guide, CRISPR-Cas Systems/genetics

المؤلفون: Nath VS; Biology Centre of the Czech Academy of Sciences, Department of Molecular Genetics, Institute of Plant Molecular Biology, Branišovská 31, 370 05 Ceske Budejovice, Czech Republic., Shrestha A; Biology Centre of the Czech Academy of Sciences, Department of Molecular Genetics, Institute of Plant Molecular Biology, Branišovská 31, 370 05 Ceske Budejovice, Czech Republic., Awasthi P; Biology Centre of the Czech Academy of Sciences, Department of Molecular Genetics, Institute of Plant Molecular Biology, Branišovská 31, 370 05 Ceske Budejovice, Czech Republic., Mishra AK; Biology Centre of the Czech Academy of Sciences, Department of Molecular Genetics, Institute of Plant Molecular Biology, Branišovská 31, 370 05 Ceske Budejovice, Czech Republic., Kocábek T; Biology Centre of the Czech Academy of Sciences, Department of Molecular Genetics, Institute of Plant Molecular Biology, Branišovská 31, 370 05 Ceske Budejovice, Czech Republic., Matoušek J; Biology Centre of the Czech Academy of Sciences, Department of Molecular Genetics, Institute of Plant Molecular Biology, Branišovská 31, 370 05 Ceske Budejovice, Czech Republic., Sečnik A; Department of Agronomy, Biotechnical Faculty, University of Ljubljana, Jamnikarjeva 101, SI-1000 Ljubljana, Slovenia., Jakše J; Department of Agronomy, Biotechnical Faculty, University of Ljubljana, Jamnikarjeva 101, SI-1000 Ljubljana, Slovenia., Radišek S; Slovenian Institute of Hop Research and Brewing, Plant Protection Department, Cesta Žalskega Tabora 2, SI-3310 Žalec, Slovenia., Hallan V; CSIR-Institute of Himalayan Bioresource Technology, Palampur-176061 India.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2020 Apr 03; Vol. 21 (7). Date of Electronic Publication: 2020 Apr 03.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Humulus/*virology , Mediator Complex/*genetics , Nicotiana/*virology , Viroids/*pathogenicity, Gene Expression Profiling ; Gene Expression Regulation, Plant ; Humulus/genetics ; Plant Leaves/genetics ; Plant Leaves/microbiology ; Plant Proteins/genetics ; Plant Viruses ; Species Specificity ; Nicotiana/genetics ; Viroids/genetics

SCR Organism: Hop stunt viroid

المؤلفون: Mishra AK; Biology Centre, Czech Academy of Sciences, Department of Molecular Genetics, Institute of Plant Molecular Biology, Branišovská 31, 370 05 České Budějovice, Czech Republic., Kocábek T; Biology Centre, Czech Academy of Sciences, Department of Molecular Genetics, Institute of Plant Molecular Biology, Branišovská 31, 370 05 České Budějovice, Czech Republic., Sukumari Nath V; Biology Centre, Czech Academy of Sciences, Department of Molecular Genetics, Institute of Plant Molecular Biology, Branišovská 31, 370 05 České Budějovice, Czech Republic., Awasthi P; Biology Centre, Czech Academy of Sciences, Department of Molecular Genetics, Institute of Plant Molecular Biology, Branišovská 31, 370 05 České Budějovice, Czech Republic., Shrestha A; Biology Centre, Czech Academy of Sciences, Department of Molecular Genetics, Institute of Plant Molecular Biology, Branišovská 31, 370 05 České Budějovice, Czech Republic., Kumar Killi U; Biology Centre, Czech Academy of Sciences, Department of Molecular Genetics, Institute of Plant Molecular Biology, Branišovská 31, 370 05 České Budějovice, Czech Republic., Jakse J; Department of Agronomy, Biotechnical Faculty, University of Ljubljana, Jamnikarjeva 101, SI-1000 Ljubljana, Slovenia., Patzak J; Hop Research Institute, Co. Ltd., Kadaňská 2525, 438 46 Žatec, Czech Republic., Krofta K; Hop Research Institute, Co. Ltd., Kadaňská 2525, 438 46 Žatec, Czech Republic., Matoušek J; Biology Centre, Czech Academy of Sciences, Department of Molecular Genetics, Institute of Plant Molecular Biology, Branišovská 31, 370 05 České Budějovice, Czech Republic.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2019 Dec 29; Vol. 21 (1). Date of Electronic Publication: 2019 Dec 29.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Humulus/*chemistry , Plant Leaves/*metabolism , Plant Proteins/*metabolism , Transcriptome/*genetics , Trichomes/*metabolism, Flavonoids/biosynthesis ; Flavonoids/chemistry ; Flavonoids/metabolism ; Gene Expression Regulation, Plant ; Gene Ontology ; Humulus/metabolism ; Plant Leaves/genetics ; Plant Proteins/genetics ; Propiophenones/chemistry ; Propiophenones/metabolism ; RNA-Seq ; Terpenes/chemistry ; Terpenes/metabolism ; Transcription Factors/metabolism ; Trichomes/genetics ; Trichomes/ultrastructure

المؤلفون: Štajner N; University of Ljubljana, Biotechnical Faculty, Department of Agronomy, Jamnikarjeva 101, SI-1000 Ljubljana, Slovenia., Radišek S; Slovenian Institute of Hop Research and Brewing, Plant Protection Department, Cesta Žalskega tabora 2, SI-3310 Žalec, Slovenia., Mishra AK; Biology Centre of the Czech Academy of Sciences, Institute of Plant Molecular Biology, Department of Molecular Genetics, Branišovská 31, 37005 České Budějovice, Czech Republic., Nath VS; Biology Centre of the Czech Academy of Sciences, Institute of Plant Molecular Biology, Department of Molecular Genetics, Branišovská 31, 37005 České Budějovice, Czech Republic., Matoušek J; Biology Centre of the Czech Academy of Sciences, Institute of Plant Molecular Biology, Department of Molecular Genetics, Branišovská 31, 37005 České Budějovice, Czech Republic., Jakše J; University of Ljubljana, Biotechnical Faculty, Department of Agronomy, Jamnikarjeva 101, SI-1000 Ljubljana, Slovenia. jernej.jakse@bf.uni-lj.si.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2019 Jun 28; Vol. 20 (13). Date of Electronic Publication: 2019 Jun 28.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Transcriptome*, Humulus/*genetics , Plant Diseases/*genetics, Humulus/virology ; Plant Diseases/virology ; Viroids/pathogenicity

المؤلفون: Mishra AK; Biology Centre of the Czech Academy of Sciences, Department of Molecular Genetics, Institute of Plant Molecular Biology, Branišovská 31, 370 05 Ceske Budejovice, Czech Republic. ajaymishra24@umbr.cas.cz., Kumar A; Biology Centre of the Czech Academy of Sciences, Department of Molecular Genetics, Institute of Plant Molecular Biology, Branišovská 31, 370 05 Ceske Budejovice, Czech Republic. atul.kumar@umbr.cas.cz., Mishra D; Biology Centre of the Czech Academy of Sciences, Department of Molecular Genetics, Institute of Plant Molecular Biology, Branišovská 31, 370 05 Ceske Budejovice, Czech Republic. deepti.mishra@umbr.cas.cz., Nath VS; Biology Centre of the Czech Academy of Sciences, Department of Molecular Genetics, Institute of Plant Molecular Biology, Branišovská 31, 370 05 Ceske Budejovice, Czech Republic. sukumari.nath@umbr.cas.cz., Jakše J; Department of Agronomy, Biotechnical Faculty, University of Ljubljana, Jamnikarjeva 101, SI-1000 Ljubljana, Slovenia. Jernej.Jakse@bf.uni-lj.si., Kocábek T; Biology Centre of the Czech Academy of Sciences, Department of Molecular Genetics, Institute of Plant Molecular Biology, Branišovská 31, 370 05 Ceske Budejovice, Czech Republic. kocabek@umbr.cas.cz., Killi UK; Biology Centre of the Czech Academy of Sciences, Department of Molecular Genetics, Institute of Plant Molecular Biology, Branišovská 31, 370 05 Ceske Budejovice, Czech Republic. killi@umbr.cas.cz., Morina F; Biology Centre of the Czech Academy of Sciences, Department of Plant Biophysics and Biochemistry, Institute of Plant Molecular Biology, Branišovská 31, 370 05 Ceske Budejovice, Czech Republic. morina@umbr.cas.cz., Matoušek J; Biology Centre of the Czech Academy of Sciences, Department of Molecular Genetics, Institute of Plant Molecular Biology, Branišovská 31, 370 05 Ceske Budejovice, Czech Republic. jmat@umbr.cas.cz.

المصدر: Viruses [Viruses] 2018 Oct 18; Vol. 10 (10). Date of Electronic Publication: 2018 Oct 18.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101509722 Publication Model: Electronic Cited Medium: Internet ISSN: 1999-4915 (Electronic) Linking ISSN: 19994915 NLM ISO Abbreviation: Viruses Subsets: MEDLINE

مواضيع طبية MeSH: Humulus/*virology , Plant Diseases/*genetics , Plant Proteins/*genetics , Plant Viruses/*physiology , Viroids/*physiology, Gene Expression Profiling ; Gene Expression Regulation, Plant ; Humulus/genetics ; Humulus/metabolism ; Plant Diseases/virology ; Plant Leaves/genetics ; Plant Leaves/metabolism ; Plant Leaves/virology ; Plant Proteins/metabolism ; Plant Viruses/genetics ; Plant Viruses/isolation & purification ; Viroids/classification ; Viroids/genetics ; Viroids/isolation & purification

المؤلفون: Mishra AK; Biology Centre of the Czech Academy of Sciences, Institute of Plant Molecular Biology, Department of Molecular Genetics, Branišovská 31, 37005, České Budějovice, Czech Republic., Duraisamy GS; Biology Centre of the Czech Academy of Sciences, Institute of Plant Molecular Biology, Department of Molecular Genetics, Branišovská 31, 37005, České Budějovice, Czech Republic., Khare M; Biology Centre of the Czech Academy of Sciences, Institute of Plant Molecular Biology, Department of Molecular Genetics, Branišovská 31, 37005, České Budějovice, Czech Republic., Kocábek T; Biology Centre of the Czech Academy of Sciences, Institute of Plant Molecular Biology, Department of Molecular Genetics, Branišovská 31, 37005, České Budějovice, Czech Republic., Jakse J; Department of Agronomy, Biotechnical Faculty, University of Ljubljana, Jamnikarjeva 101, SI-1000, Ljubljana, Slovenia., Bříza J; Biology Centre of the Czech Academy of Sciences, Institute of Plant Molecular Biology, Department of Molecular Genetics, Branišovská 31, 37005, České Budějovice, Czech Republic., Patzak J; Hop Research Institute, Co. Ltd., Kadaňská 2525, 43846, Žatec, Czech Republic., Sano T; Faculty of Agriculture and Life Science, Department of Applied Biosciences, Hirosaki University, Hirosaki, Aomori, 036-8561, Japan., Matoušek J; Biology Centre of the Czech Academy of Sciences, Institute of Plant Molecular Biology, Department of Molecular Genetics, Branišovská 31, 37005, České Budějovice, Czech Republic. jmat@umbr.cas.cz.

المصدر: BMC genomics [BMC Genomics] 2018 Oct 11; Vol. 19 (1), pp. 739. Date of Electronic Publication: 2018 Oct 11.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 100965258 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2164 (Electronic) Linking ISSN: 14712164 NLM ISO Abbreviation: BMC Genomics Subsets: MEDLINE

مواضيع طبية MeSH: Gene Expression Profiling* , Genomics*, Humulus/*genetics , Plant Proteins/*genetics , Transcription Factors/*genetics, Gene Expression ; Molecular Sequence Annotation ; Plants, Genetically Modified

المؤلفون: Kocábek T; Biology Centre of the Czech Academy of Sciences v.v.i, Institute of Plant Molecular Biology, Branišovská 31, 370 05 České Budějovice, Czech Republic. Electronic address: kocabek@umbr.cas.cz., Mishra AK; Biology Centre of the Czech Academy of Sciences v.v.i, Institute of Plant Molecular Biology, Branišovská 31, 370 05 České Budějovice, Czech Republic., Matoušek J; Biology Centre of the Czech Academy of Sciences v.v.i, Institute of Plant Molecular Biology, Branišovská 31, 370 05 České Budějovice, Czech Republic., Patzak J; Hop Research Institute Co. Ltd., Kadaňská 2525, 438 46 Žatec, Czech Republic., Lomnická A; Biology Centre of the Czech Academy of Sciences v.v.i, Institute of Plant Molecular Biology, Branišovská 31, 370 05 České Budějovice, Czech Republic; University of South Bohemia in České Budějovice, Faculty of Science, Branišovská 1760, 370 05 České Budějovice, Czech Republic., Khare M; Biology Centre of the Czech Academy of Sciences v.v.i, Institute of Plant Molecular Biology, Branišovská 31, 370 05 České Budějovice, Czech Republic., Krofta K; Hop Research Institute Co. Ltd., Kadaňská 2525, 438 46 Žatec, Czech Republic.

المصدر: Plant science : an international journal of experimental plant biology [Plant Sci] 2018 Apr; Vol. 269, pp. 32-46. Date of Electronic Publication: 2018 Jan 31.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Ireland Country of Publication: Ireland NLM ID: 9882015 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2259 (Electronic) Linking ISSN: 01689452 NLM ISO Abbreviation: Plant Sci Subsets: MEDLINE

مواضيع طبية MeSH: Flavonoids/*biosynthesis , Humulus/*genetics , Plant Proteins/*genetics , Transcription Factors/*genetics, Amino Acid Sequence ; Gene Expression Profiling ; Humulus/metabolism ; Phylogeny ; Plant Leaves/metabolism ; Plant Proteins/chemistry ; Plant Proteins/metabolism ; Plants, Genetically Modified/genetics ; Plants, Genetically Modified/metabolism ; Sequence Alignment ; Nicotiana/genetics ; Nicotiana/metabolism ; Transcription Factors/chemistry ; Transcription Factors/metabolism