المؤلفون: Alexander J. Ainscough, Timothy J. Smith, Maike Haensel, Christopher J. Rhodes, Adam Fellows, Harry J. Whitwell, Eleni Vasilaki, Kelly Gray, Adrian Freeman, Luke S. Howard, John Wharton, Benjamin Dunmore, Paul D. Upton, Martin R. Wilkins, Joshua B. Edel, Beata Wojciak-Stothard

المساهمون: Fellows, Adam [0000-0002-9975-3795], Howard, Luke S [0000-0003-2822-210X], Wharton, John [0000-0001-8110-2575], Upton, Paul D [0000-0003-2716-4921], Wilkins, Martin R [0000-0003-3926-1171], Edel, Joshua B [0000-0001-5870-8659], Wojciak-Stothard, Beata [0000-0002-6607-7372], Apollo - University of Cambridge Repository

مصطلحات موضوعية: Pulmonary Arterial Hypertension, 631/1647, Hypertension, Pulmonary, SOXF Transcription Factors, article, Humans, Medicine (miscellaneous), 631/80, Bone Morphogenetic Protein Receptors, Type II, General Agricultural and Biological Sciences, Epoprostenol, General Biochemistry, Genetics and Molecular Biology, 692/420

وصف الملف: application/pdf; application/zip; text/xml

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bc1d32fe57b1a6574392ac1146e3d16
http://hdl.handle.net/10044/1/101160

المؤلفون: Beata Wojciak-Stothard, Vahitha B. Abdul-Salam, Giuseppe Faggian, Michele Miragoli, Roman Y. Medvedev, Julia Gorelik, Anita Alvarez-Laviada, Jose L. Sanchez-Alonso, Eef Dries, Natalia A. Trayanova, Stefano Rossi, Tilo Schorn

المصدر: Hypertension

مصطلحات موضوعية: Male, 0301 basic medicine, medicine.medical_specialty, Hypertension, Pulmonary, chemistry.chemical_element, Stimulation, Vascular Remodeling, 030204 cardiovascular system & hematology, Calcium, Ryanodine receptor 2, Article, Rats, Sprague-Dawley, 03 medical and health sciences, 0302 clinical medicine, Right ventricular hypertrophy, Internal medicine, Internal Medicine, medicine, Animals, Myocyte, Myocytes, Cardiac, Calcium Signaling, Monocrotaline, Hypertrophy, Right Ventricular, business.industry, Colocalization, medicine.disease, Pulmonary hypertension, Rats, 030104 developmental biology, medicine.anatomical_structure, chemistry, Ventricle, Cardiology, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69749498ed5a496fdcd1a460bb090727
https://doi.org/10.1161/hypertensionaha.120.14858

المؤلفون: Thomas A. J. McKinnon, Mark Southwood, Alexander J. Ainscough, Lucie Duluc, Martin R. Wilkins, Lulwah Aldabbous, Charaka Hadinnapola, Vahitha B. Abdul-Salam, Beata Wojciak-Stothard, Mark Toshner, Joanna Pepke-Zaba

المساهمون: Embassy Of State Of Kuwait, British Heart Foundation

المصدر: Arteriosclerosis, Thrombosis, and Vascular Biology. 36:2078-2087

مصطلحات موضوعية: Male, 0301 basic medicine, Pathology, medicine.medical_specialty, Angiogenesis, Idiopathic Pulmonary Hypertension, Myocytes, Smooth Muscle, hypertension, pulmonary, Pulmonary Artery, Biology, Transfection, 1102 Cardiovascular Medicine And Haematology, Muscle, Smooth, Vascular, Mice, 03 medical and health sciences, cell movement, neutrophils, Chloride Channels, homeostasis, medicine, Animals, Humans, Endothelial dysfunction, Cells, Cultured, Cell Proliferation, Peroxidase, Lung, Neovascularization, Pathologic, NF-kappa B, 1103 Clinical Sciences, Hydrogen Peroxide, Neutrophil extracellular traps, medicine.disease, Pulmonary hypertension, Endothelin 1, Coculture Techniques, endothelial cells, Toll-Like Receptor 4, 030104 developmental biology, medicine.anatomical_structure, Cardiovascular System & Hematology, Case-Control Studies, Neutrophil elastase, endothelin-1, biology.protein, RNA Interference, Cardiology and Cardiovascular Medicine, extracellular traps, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6fd7d92ca48f2481981a6699eabb1e9
https://doi.org/10.1161/atvbaha.116.307634

المؤلفون: Vahitha B, Abdul-Salam, Giusy, Russomanno, Chen, Chien-Nien, Abdul S, Mahomed, Luke A, Yates, Martin R, Wilkins, Lan, Zhao, Magdalena, Gierula, Oliver, Dubois, Ute, Schaeper, Jens, Endruschat, Beata, Wojciak-Stothard

المصدر: Circulation research. 124(1)

مصطلحات موضوعية: Proteomics, Monocrotaline, ADP-Ribosylation Factors, Hypertension, Pulmonary, Endothelial Cells, Pulmonary Artery, Triazoles, Bone Morphogenetic Protein Receptors, Type II, Article, Rats, Mice, Inbred C57BL, Mitochondrial Proteins, Disease Models, Animal, RNAi Therapeutics, ADP-Ribosylation Factor 6, Chloride Channels, Animals, Humans, Molecular Targeted Therapy, Inflammation Mediators, RNA, Small Interfering, Hypoxia, Antihypertensive Agents, Cells, Cultured, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::11e0d57e920e035e6c9ef4e7520c545b
https://pubmed.ncbi.nlm.nih.gov/30605416

المؤلفون: John Wharton, Olivier Dubois, Lucie Duluc, Lucio Iannone, Christopher J. Rhodes, Beata Wojciak-Stothard, Lan Zhao, James Leiper, Martin R. Wilkins

المصدر: Biochemical Journal. 462:103-112

مصطلحات موضوعية: Male, Genetically modified mouse, medicine.medical_specialty, Hypertension, Pulmonary, Myocytes, Smooth Muscle, Mice, Transgenic, Biology, Arginine, Biochemistry, Amidohydrolases, Pathogenesis, Mice, chemistry.chemical_compound, Internal medicine, medicine, Animals, Humans, Familial Primary Pulmonary Hypertension, Endothelial dysfunction, Hypoxia, Cyclic GMP, Lung, Molecular Biology, Cells, Cultured, Endothelial Cells, Cell Biology, Hypoxia (medical), medicine.disease, Pulmonary hypertension, Nitric oxide synthase, MicroRNAs, Endocrinology, medicine.anatomical_structure, chemistry, biology.protein, medicine.symptom, Asymmetric dimethylarginine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7359e2f76b07dd23e041cbf1d2e93d1
https://doi.org/10.1042/bj20140486

المؤلفون: Stuart H. Yuspa, Christina Lisk, Christopher J. Rhodes, Robert Edwards, Luke Howard, Ka Hou Lao, Zoe Loomis, Beata Wojciak-Stothard, Vahitha B. Abdul-Salam, J. Simon R. Gibbs, John C. Edwards, Lan Zhao, Hilda Tsang, David Irwin, John Wharton, Martin R. Wilkins, Kurt R. Stenmark

المصدر: Circulation. 129:1770-1780

مصطلحات موضوعية: Male, Pathology, medicine.medical_specialty, Endothelium, Hypertension, Pulmonary, Mice, Inbred Strains, Pulmonary Artery, Article, Muscle, Smooth, Vascular, Mitochondrial Proteins, Rats, Sprague-Dawley, Mice, Vasculogenesis, Chloride Channels, Physiology (medical), medicine.artery, medicine, Animals, Humans, Familial Primary Pulmonary Hypertension, Endothelial dysfunction, Cells, Cultured, Mice, Knockout, Tube formation, business.industry, Transcription Factor RelA, Hypoxia-Inducible Factor 1, alpha Subunit, medicine.disease, Pulmonary hypertension, Rats, Vascular endothelial growth factor B, Vascular endothelial growth factor A, medicine.anatomical_structure, Pulmonary artery, Endothelium, Vascular, Cardiology and Cardiovascular Medicine, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78570f0979300b060de6e6940cbf0c37
https://doi.org/10.1161/circulationaha.113.006797

المؤلفون: Lucie, Duluc, Blerina, Ahmetaj-Shala, Jane, Mitchell, Vahitha B, Abdul-Salam, Abdul S, Mahomed, Lulwah, Aldabbous, Eduardo, Oliver, Lucio, Iannone, Olivier D, Dubois, Elisabeth M, Storck, Edward W, Tate, Lan, Zhao, Martin R, Wilkins, Beata, Wojciak-Stothard

المصدر: Cardiovascular research. 113(3)

مصطلحات موضوعية: Male, Proteomics, Time Factors, Hypertension, Pulmonary, Protein Prenylation, Endothelial Cells, Pulmonary Artery, Quinolones, Transfection, Mice, Inbred C57BL, Vasodilation, Disease Models, Animal, Phenotype, Vasoconstriction, Animals, Farnesyltranstransferase, Humans, Enzyme Inhibitors, Hypoxia, rhoB GTP-Binding Protein, Antihypertensive Agents, Cells, Cultured, Cell Proliferation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::b462225d9147f1d8da2cb36de9b662e6
https://pubmed.ncbi.nlm.nih.gov/28395024

المؤلفون: Elisabeth M. Storck, Beata Wojciak-Stothard

المصدر: Vascular Pharmacology. 58:202-210

مصطلحات موضوعية: Lung Diseases, rho GTP-Binding Proteins, Pharmacology, Pulmonary Circulation, Pathology, medicine.medical_specialty, Physiology, Cell growth, Hypertension, Pulmonary, Morphogenesis, Disease, Biology, Lung injury, medicine.disease, Pulmonary hypertension, Actins, Pulmonary embolism, Vesicular transport protein, Gene expression, medicine, Animals, Humans, Molecular Medicine, Vascular Diseases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f328a3652ef854d422bb8d049bb74e89
https://doi.org/10.1016/j.vph.2012.09.004

المؤلفون: Robin Condliffe, Stefanie Dimmeler, Andreas M. Zeiher, Luke Howard, Ralph T. Schermuly, Tino Roexe, Beata Wojciak-Stothard, Hilda Tsang, Christopher J. Rhodes, David G. Kiely, J. Simon R. Gibbs, Les Huson, Anob Chakrabarti, Hossein Ardeschir Ghofrani, Henning Tiede, Charles A. Elliot, Allan Lawrie, Reinier A. Boon, John Wharton, Martin R. Wilkins

المساهمون: Physiology

المصدر: American Journal of Respiratory and Critical Care Medicine, 187(3), 294-302. American Thoracic Society
Rhodes, C J, Wharton, J, Boon, R A, Roexe, T, Tsang, H, Wojciak-Stothard, B, Chakrabarti, A, Howard, L S, Gibbs, J S R, Lawrie, A, Condliffe, R, Elliot, C A, Kiely, D G, Huson, L, Ghofrani, H A, Tiede, H, Schermuly, R, Zeiher, A M, Dimmeler, S & Wilkins, M R 2013, ' Reduced microrna-150 is associated with poor survival in pulmonary arterial hypertension ', American Journal of Respiratory and Critical Care Medicine, vol. 187, no. 3, pp. 294-302 . https://doi.org/10.1164/rccm.201205-0839OC

مصطلحات موضوعية: Pulmonary and Respiratory Medicine, Adult, Male, medicine.medical_specialty, Pathology, Microarray, Hypertension, Pulmonary, Down-Regulation, Critical Care and Intensive Care Medicine, Gastroenterology, Polymerase Chain Reaction, Severity of Illness Index, Pathogenesis, Cohort Studies, Age Distribution, Internal medicine, miR-150, microRNA, London, medicine, Animals, Humans, Familial Primary Pulmonary Hypertension, business.industry, Plasma levels, Middle Aged, medicine.disease, Microarray Analysis, Pulmonary hypertension, Survival Analysis, Microvesicles, Rats, Disease Models, Animal, MicroRNAs, Real-time polymerase chain reaction, ROC Curve, Female, business, Biomarkers

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1288ec66d00044fe108d7392922e40a
https://pubmed.ncbi.nlm.nih.gov/23220912

المؤلفون: Beata, Wojciak-Stothard, Lan, Zhao, Eduardo, Oliver, Olivier, Dubois, Yixing, Wu, Dimitris, Kardassis, Eleftheria, Vasilaki, Minzhou, Huang, Jane A, Mitchell, Louise S, Harrington, Harrington, Louise, George C, Prendergast, Martin R, Wilkins

مصطلحات موضوعية: Male, RHOA, Time Factors, Physiology, RHOB, Muscle, Smooth, Vascular, Mice, Cell Movement, Hypoxic pulmonary vasoconstriction, Stress Fibers, Serine, Familial Primary Pulmonary Hypertension, Enzyme Inhibitors, Phosphorylation, Hypoxia, rhoB GTP-Binding Protein, Rho-associated protein kinase, Cells, Cultured, Mice, Knockout, Actomyosin, Cell Hypoxia, RNA Interference, medicine.symptom, Cardiology and Cardiovascular Medicine, Myosin Light Chains, Polyunsaturated Alkamides, Hypertension, Pulmonary, Myocytes, Smooth Muscle, Polyenes, Biology, Pulmonary Artery, Transfection, Article, Capillary Permeability, RhoB GTP-Binding Protein, medicine, Animals, Farnesyltranstransferase, Humans, Cell Proliferation, Endothelial Cells, Hypoxia (medical), medicine.disease, Hypoxia-Inducible Factor 1, alpha Subunit, Pulmonary hypertension, Enzyme Activation, Mice, Inbred C57BL, Disease Models, Animal, Vasoconstriction, Chronic Disease, biology.protein, Cancer research, rhoA GTP-Binding Protein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee40733b074cd1218b8fb146cc5e34d5
http://hdl.handle.net/10044/1/19686