المؤلفون: Maher, Steven P, Bakowski, Malina A, Vantaux, Amelie, Flannery, Erika L, Andolina, Chiara, Gupta, Mohit, Antonova-Koch, Yevgeniya, Argomaniz, Magdalena, Monica, Cabrera-Mora, Brice, Campo, Chao, Alexander T, Chatterjee, Arnab K, Cheng, Wayne T, Cooper, Caitlin A, Karissa, Cottier, Galinski, Mary R, Harupa-Chung, Anke, Ji, Hana, Joseph, Sean B, Lenz, Todd, Lonardi, Stefano, Matheson, Jessica, Mikolajczak, Sebastian A, Padin-Irizarry, Vivian, Pan, Kastin, Peneau, Julie, Prudhomme, Jacques, Roesch, Camille, Ruberto, Anthony A, Sabnis, Saniya S, Saney, Celia L, Sattabongkot, Jetsumon, Sereshki, Saleh, Suriyakan, Sangrawee, Timothy, Moeller, Ubalee, Ratawan, Wang, Yinsheng, Wasisakun, Praphan, Yin, Jiekai, McNamara, Case W, Joyner, Chester J, Nosten, Francois, Witkowski, Benoit, Le Roch, Karine G, Kyle, Dennis E

المصدر: bioRxiv. 4(02-10)

مصطلحات موضوعية: Rare Diseases, Biotechnology, Orphan Drug, Infectious Diseases, Malaria, Genetics, Vector-Borne Diseases, Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, Infection, Good Health and Well Being

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/5xg122bt

المؤلفون: Caldwell, Nicola, Afshar, Rana, Baragaña, Beatriz, Bustinduy, Amaya L, Caffrey, Conor R, Collins, James J, Fusco, Daniela, Garba, Amadou, Gardner, Mark, Gomes, Mireille, Hoffmann, Karl F, Hsieh, Michael, Lo, Nathan C, McNamara, Case W, Nono, Justin Komguep, Padalino, Gilda, Read, Kevin D, Roestenberg, Meta, Spangenberg, Thomas, Specht, Sabine, Gilbert, Ian H

المصدر: ACS Infectious Diseases. 9(5)

مصطلحات موضوعية: Medical Microbiology, Biomedical and Clinical Sciences, Orphan Drug, Vector-Borne Diseases, Infectious Diseases, Rare Diseases, Digestive Diseases, Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, Infection, Good Health and Well Being, Animals, London, Schistosomiasis, Praziquantel, Anthelmintics, Schistosoma, schistosomiasis, neglected tropical disease, infectious disease, drug discovery, therapeutic s, anthelmintic s, target product profile, anthelmintics, therapeutics, Medical microbiology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/17m2f4vh

المؤلفون: Tyagi, Rahul, Bulman, Christina A, Cho-Ngwa, Fidelis, Fischer, Chelsea, Marcellino, Chris, Arkin, Michelle R, McKerrow, James H, McNamara, Case W, Mahoney, Matthew, Tricoche, Nancy, Jawahar, Shabnam, Janetka, James W, Lustigman, Sara, Sakanari, Judy, Mitreva, Makedonka

المصدر: Pathogens. 10(1)

مصطلحات موضوعية: Biological Sciences, Biomedical and Clinical Sciences, Microbiology, Immunology, Medical Microbiology, Biotechnology, Vector-Borne Diseases, Infectious Diseases, Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, Infection, Good Health and Well Being, parasitic nematodes, filarial nematodes, whole worm assay, in vitro, target class repurposing, anthelmintics, macrofilaricides, Medical microbiology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/9z3250qp

المؤلفون: Bakowski, Malina A, Beutler, Nathan, Wolff, Karen C, Kirkpatrick, Melanie G, Chen, Emily, Nguyen, Tu-Trinh H, Riva, Laura, Shaabani, Namir, Parren, Mara, Ricketts, James, Gupta, Anil K, Pan, Kastin, Kuo, Peiting, Fuller, MacKenzie, Garcia, Elijah, Teijaro, John R, Yang, Linlin, Sahoo, Debashis, Chi, Victor, Huang, Edward, Vargas, Natalia, Roberts, Amanda J, Das, Soumita, Ghosh, Pradipta, Woods, Ashley K, Joseph, Sean B, Hull, Mitchell V, Schultz, Peter G, Burton, Dennis R, Chatterjee, Arnab K, McNamara, Case W, Rogers, Thomas F

المصدر: Nature Communications. 12(1)

مصطلحات موضوعية: Prevention, Pneumonia & Influenza, Lung, Emerging Infectious Diseases, Pneumonia, Infectious Diseases, Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, Infection, Good Health and Well Being, Animals, Antiviral Agents, COVID-19, Cell Line, Cytidine, Databases, Pharmaceutical, Drug Discovery, Drug Evaluation, Preclinical, Drug Repositioning, HeLa Cells, High-Throughput Screening Assays, Humans, Hydroxylamines, Mesocricetus, Nelfinavir, Pandemics, SARS-CoV-2, Virus Replication, COVID-19 Drug Treatment, Hela Cells

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/77f9r1t7

المؤلفون: Antonova-Koch, Yevgeniya, Meister, Stephan, Abraham, Matthew, Luth, Madeline R, Ottilie, Sabine, Lukens, Amanda K, Sakata-Kato, Tomoyo, Vanaerschot, Manu, Owen, Edward, Jado, Juan Carlos, Maher, Steven P, Calla, Jaeson, Plouffe, David, Zhong, Yang, Chen, Kaisheng, Chaumeau, Victor, Conway, Amy J, McNamara, Case W, Ibanez, Maureen, Gagaring, Kerstin, Serrano, Fernando Neria, Eribez, Korina, Taggard, Cullin McLean, Cheung, Andrea L, Lincoln, Christie, Ambachew, Biniam, Rouillier, Melanie, Siegel, Dionicio, Nosten, François, Kyle, Dennis E, Gamo, Francisco-Javier, Zhou, Yingyao, Llinás, Manuel, Fidock, David A, Wirth, Dyann F, Burrows, Jeremy, Campo, Brice, Winzeler, Elizabeth A

المصدر: Science. 362(6419)

مصطلحات موضوعية: Medical Microbiology, Biomedical and Clinical Sciences, Clinical Sciences, HIV/AIDS, Infectious Diseases, Vector-Borne Diseases, Rare Diseases, Malaria, Orphan Drug, 5.1 Pharmaceuticals, Development of treatments and therapeutic interventions, Infection, Good Health and Well Being, Antimalarials, Chemoprevention, Drug Discovery, Drug Evaluation, Preclinical, Humans, Mitochondria, Plasmodium, General Science & Technology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/7nt3b34h

المؤلفون: Flannery, Erika L, McNamara, Case W, Kim, Sang Wan, Kato, Tomoyo Sakata, Li, Fengwu, Teng, Christine H, Gagaring, Kerstin, Manary, Micah J, Barboa, Rachel, Meister, Stephan, Kuhen, Kelli, Vinetz, Joseph M, Chatterjee, Arnab K, Winzeler, Elizabeth A

المصدر: ACS Chemical Biology. 10(2)

مصطلحات موضوعية: Biological Sciences, Chemical Sciences, Malaria, Infectious Diseases, Orphan Drug, Rare Diseases, Vector-Borne Diseases, Genetics, Antimicrobial Resistance, Human Genome, Infection, Adenosine Triphosphatases, Antimalarials, Drug Resistance, Gene Expression Regulation, Enzymologic, Indoles, Models, Molecular, Molecular Structure, Mutation, Plasmodium falciparum, Protein Conformation, Pyrazoles, Sodium, Organic Chemistry, Biological sciences, Chemical sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/33t0g7cr

المؤلفون: Manary, Micah J, Singhakul, Suriya S, Flannery, Erika L, Bopp, Selina ER, Corey, Victoria C, Bright, Andrew Taylor, McNamara, Case W, Walker, John R, Winzeler, Elizabeth A

المصدر: BMC Bioinformatics. 15(1)

مصطلحات موضوعية: Biological Sciences, Bioinformatics and Computational Biology, Genetics, Vector-Borne Diseases, Human Genome, Malaria, Rare Diseases, Biotechnology, Infectious Diseases, Infection, Good Health and Well Being, Antimalarials, DNA Copy Number Variations, DNA, Protozoan, Drug Resistance, Genome, Protozoan, Genomics, Plasmodium falciparum, Polymorphism, Single Nucleotide, Sequence Analysis, DNA, Software, Sequencing, Genome, Polymorphism, Variant, Mathematical Sciences, Information and Computing Sciences, Bioinformatics, Biological sciences, Information and computing sciences, Mathematical sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/42p2d6b9

المؤلفون: Zeeman, Anne-Marie, van Amsterdam, Sandra M, McNamara, Case W, der Wel, Annemarie Voorberg-van, Klooster, Els J, van den Berg, Alexander, Remarque, Edmond J, Plouffe, David M, van Gemert, Geert-Jan, Luty, Adrian, Sauerwein, Robert, Gagaring, Kerstin, Borboa, Rachel, Chen, Zhong, Kuhen, Kelli, Glynne, Richard J, Chatterjee, Arnab K, Nagle, Advait, Roland, Jason, Winzeler, Elizabeth A, Leroy, Didier, Campo, Brice, Diagana, Thierry T, Yeung, Bryan KS, Thomas, Alan W, Kocken, Clemens HM

المصدر: Antimicrobial Agents and Chemotherapy. 58(3)

مصطلحات موضوعية: Medical Microbiology, Biomedical and Clinical Sciences, Clinical Sciences, Orphan Drug, Digestive Diseases, Liver Disease, Malaria, Prevention, Infectious Diseases, Rare Diseases, Vector-Borne Diseases, Biotechnology, 5.1 Pharmaceuticals, Development of treatments and therapeutic interventions, Infection, Good Health and Well Being, Animals, Antimalarials, Drug Evaluation, Preclinical, Female, Hepatocytes, Imidazoles, In Vitro Techniques, Liver, Macaca mulatta, Mice, Mice, Inbred ICR, Plasmodium cynomolgi, Pyrazines, Sporozoites, Microbiology, Pharmacology and Pharmaceutical Sciences, Medical microbiology, Pharmacology and pharmaceutical sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/3fd2d5tk

المؤلفون: McNamara, Case W, Lee, Marcus CS, Lim, Chek Shik, Lim, Siau Hoi, Roland, Jason, Nagle, Advait, Simon, Oliver, Yeung, Bryan KS, Chatterjee, Arnab K, McCormack, Susan L, Manary, Micah J, Zeeman, Anne-Marie, Dechering, Koen J, Kumar, TR Santha, Henrich, Philipp P, Gagaring, Kerstin, Ibanez, Maureen, Kato, Nobutaka, Kuhen, Kelli L, Fischli, Christoph, Rottmann, Matthias, Plouffe, David M, Bursulaya, Badry, Meister, Stephan, Rameh, Lucia, Trappe, Joerg, Haasen, Dorothea, Timmerman, Martijn, Sauerwein, Robert W, Suwanarusk, Rossarin, Russell, Bruce, Renia, Laurent, Nosten, Francois, Tully, David C, Kocken, Clemens HM, Glynne, Richard J, Bodenreider, Christophe, Fidock, David A, Diagana, Thierry T, Winzeler, Elizabeth A

المصدر: Nature. 504(7479)

مصطلحات موضوعية: Medical Microbiology, Biomedical and Clinical Sciences, Clinical Sciences, Orphan Drug, Prevention, Infectious Diseases, Rare Diseases, Malaria, Vector-Borne Diseases, Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, Infection, Good Health and Well Being, 1-Phosphatidylinositol 4-Kinase, Adenosine Triphosphate, Animals, Binding Sites, Cytokinesis, Drug Resistance, Fatty Acids, Female, Hepatocytes, Humans, Imidazoles, Life Cycle Stages, Macaca mulatta, Male, Models, Biological, Models, Molecular, Phosphatidylinositol Phosphates, Plasmodium, Pyrazoles, Quinoxalines, Reproducibility of Results, Schizonts, rab GTP-Binding Proteins, General Science & Technology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/31f5h8fc

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