المؤلفون: Liu J; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015GD, The Netherlands. jun.liu@ndph.ox.ac.uk.; Nuffield Department of Population Health, University of Oxford, Oxford, OX3 7FL, UK. jun.liu@ndph.ox.ac.uk., Carnero-Montoro E; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015GD, The Netherlands.; Center for Genomics and Oncological Research, GENYO, Pfizer/University of Granada/Andalusian Government, PTS, Granada, 18007, Spain.; Department of Twin Research and Genetic Epidemiology, King's College London, London, WC2R 2LS, UK., van Dongen J; Department of Biological Psychology, Amsterdam Public Health (APH) research institute, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, 1081BT, The Netherlands., Lent S; Department of Biostatistics, Boston University School of Public Health, Boston, MA, 02118, USA., Nedeljkovic I; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015GD, The Netherlands., Ligthart S; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015GD, The Netherlands., Tsai PC; Department of Twin Research and Genetic Epidemiology, King's College London, London, WC2R 2LS, UK.; Department of Biomedical Sciences, Chang Gung University, Taoyuan, 333, Taiwan.; Division of Allergy, Asthma, and Rheumatology, Department of Pediatrics, Chang Gung Memorial Hospital, Linkou, 333, Taiwan., Martin TC; Department of Twin Research and Genetic Epidemiology, King's College London, London, WC2R 2LS, UK.; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Mandaviya PR; Department of Internal Medicine, Section of Pharmacology Vascular and Metabolic Diseases, Erasmus University Medical Center, Rotterdam, 3015GD, The Netherlands., Jansen R; Department of Psychiatry and Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, 1081BT, The Netherlands., Peters MJ; Department of Internal Medicine, Section of Pharmacology Vascular and Metabolic Diseases, Erasmus University Medical Center, Rotterdam, 3015GD, The Netherlands., Duijts L; Division of Neonatology, Department of Pediatrics, Erasmus University Medical Center, Rotterdam, 3015GD, The Netherlands.; Division of Respiratory Medicine, Department of Pediatrics, Erasmus University Medical Center, Rotterdam, 3015GD, The Netherlands., Jaddoe VWV; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015GD, The Netherlands.; Department of Pediatrics, Erasmus University Medical Center, Rotterdam, 3015GD, The Netherlands.; Generation R Study Group, Erasmus University Medical Center, Rotterdam, 3015GD, The Netherlands., Tiemeier H; Department of Child and Adolescent Psychiatry, Erasmus University Medical Center, Rotterdam, 3015GD, The Netherlands.; Department of Social and Behavioral Science, Harvard TH Chan School of Public Health, Boston, MA, 02115, USA., Felix JF; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015GD, The Netherlands.; Department of Pediatrics, Erasmus University Medical Center, Rotterdam, 3015GD, The Netherlands.; Generation R Study Group, Erasmus University Medical Center, Rotterdam, 3015GD, The Netherlands., Willemsen G; Department of Biological Psychology, Amsterdam Public Health (APH) research institute, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, 1081BT, The Netherlands., de Geus EJC; Department of Biological Psychology, Amsterdam Public Health (APH) research institute, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, 1081BT, The Netherlands., Chu AY; The Population Sciences Branch, Division of Intramural Research, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, 20814, USA.; The Framingham Heart Study, National Heart, Lung and Blood Institute, National Institutes of Health, Framingham, MA, 01702, USA., Levy D; The Population Sciences Branch, Division of Intramural Research, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, 20814, USA.; The Framingham Heart Study, National Heart, Lung and Blood Institute, National Institutes of Health, Framingham, MA, 01702, USA., Hwang SJ; The Population Sciences Branch, Division of Intramural Research, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, 20814, USA.; The Framingham Heart Study, National Heart, Lung and Blood Institute, National Institutes of Health, Framingham, MA, 01702, USA., Bressler J; Human Genetics Center, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, 77030, USA., Gondalia R; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, 27599, USA., Salfati EL; Department of Medicine, Stanford University School of Medicine, Stanford, CA, 94305, USA., Herder C; German Center for Diabetes Research (DZD), München-Neuherberg, 85764, Germany.; Institute for Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich Heine University Düsseldorf, Düsseldorf, 40225, Germany.; Division of Endocrinology and Diabetology, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, 40225, Germany., Hidalgo BA; Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, 35233, USA., Tanaka T; Translational Gerontology Branch, National Institute on Aging, Baltimore, MD, 21224, USA., Moore AZ; Translational Gerontology Branch, National Institute on Aging, Baltimore, MD, 21224, USA., Lemaitre RN; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, 98101, USA., Jhun MA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, 48109, USA., Smith JA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, 48109, USA., Sotoodehnia N; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, 98101, USA., Bandinelli S; Geriatric Unit, Azienda Sanitaria di Firenze, Florence, 50137, Italy., Ferrucci L; Translational Gerontology Branch, National Institute on Aging, Baltimore, MD, 21224, USA., Arnett DK; School of Public Health, University of Kentucky, Lexington, KY, 40536, USA., Grallert H; German Center for Diabetes Research (DZD), München-Neuherberg, 85764, Germany.; Research Unit of Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum München Research Center for Environmental Health, Neuherberg, 85764, Germany., Assimes TL; Department of Medicine, Stanford University School of Medicine, Stanford, CA, 94305, USA., Hou L; Center for Population Epigenetics, Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University Chicago, Evanston, IL, 60611, USA.; Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA., Baccarelli A; Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY, 10032, USA., Whitsel EA; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, 27599, USA.; Department of Medicine, University of North Carolina School of Medicine, Chapel Hill, North Carolina, NC, 27516, USA., van Dijk KW; Department of Human Genetics, Leiden University Medical Center, Leiden, 2333ZA, The Netherlands.; Department of Medicine, Division of Endocrinology, Leiden University Medical Center, Leiden, 2333ZA, The Netherlands., Amin N; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015GD, The Netherlands., Uitterlinden AG; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015GD, The Netherlands.; Department of Internal Medicine, Section of Pharmacology Vascular and Metabolic Diseases, Erasmus University Medical Center, Rotterdam, 3015GD, The Netherlands., Sijbrands EJG; Department of Internal Medicine, Section of Pharmacology Vascular and Metabolic Diseases, Erasmus University Medical Center, Rotterdam, 3015GD, The Netherlands., Franco OH; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015GD, The Netherlands.; Institute of Social and Preventive Medicine (ISPM), University of Bern, Bern, 3012, Switzerland., Dehghan A; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015GD, The Netherlands.; Department of Epidemiology and Biostatistics, Imperial College London, London, SW7 2AZ, UK., Spector TD; Department of Twin Research and Genetic Epidemiology, King's College London, London, WC2R 2LS, UK., Dupuis J; Department of Biostatistics, Boston University School of Public Health, Boston, MA, 02118, USA., Hivert MF; Department of Medicine, Université de Sherbrooke, Sherbrooke, QC, J1K0A5, Canada.; Diabetes Unit, Massachusetts General Hospital, Boston, MA, 02114, USA.; Division of Chronic Disease Research Across the Lifecourse, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, 02215, USA., Rotter JI; The Institute for Translational Genomics and Population Sciences and Departments of Pediatrics and Medicine, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA, 90502, USA., Meigs JB; Department of Medicine, Harvard Medical School, Boston, MA, 02115, USA.; Division of General Internal Medicine, Massachusetts General Hospital, Boston, MA, 02114, USA.; Programs in Metabolism and Medical & Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Pankow JS; Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, 55455, USA., van Meurs JBJ; CARIM School for Cardiovascular Diseases, Maastricht Centre for Systems Biology (MaCSBio), and Departments of Biochemistry and Physiology, Maastricht University, Maastricht, 6211LK, The Netherlands., Isaacs A; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015GD, The Netherlands.; CARIM School for Cardiovascular Diseases, Maastricht Centre for Systems Biology (MaCSBio), and Departments of Biochemistry and Physiology, Maastricht University, Maastricht, 6211LK, The Netherlands., Boomsma DI; Department of Biological Psychology, Amsterdam Public Health (APH) research institute, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, 1081BT, The Netherlands., Bell JT; Department of Twin Research and Genetic Epidemiology, King's College London, London, WC2R 2LS, UK., Demirkan A; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015GD, The Netherlands. a.demirkan@surrey.ac.uk.; Department of Genetics, University Medical Center Groningen, Groningen, 9713GZ, The Netherlands. a.demirkan@surrey.ac.uk.; Section of Statistical Multi-Omics, Department of Experimental and Clinical Research, School of Bioscience and Medicine, Univeristy of Surrey, Guildford, GU2 7XH, UK. a.demirkan@surrey.ac.uk., van Duijn CM; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015GD, The Netherlands. cornelia.vanduijn@ndph.ox.ac.uk.; Nuffield Department of Population Health, University of Oxford, Oxford, OX3 7FL, UK. cornelia.vanduijn@ndph.ox.ac.uk.; Leiden Academic Center for Drug Research, Leiden University, Leiden, 2311EZ, The Netherlands. cornelia.vanduijn@ndph.ox.ac.uk.

المصدر: Nature communications [Nat Commun] 2019 Jun 13; Vol. 10 (1), pp. 2581. Date of Electronic Publication: 2019 Jun 13.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: DNA Methylation/*physiology , Diabetes Mellitus, Type 2/*genetics , Glucose/*metabolism , Insulin/*metabolism , Obesity/*genetics, Adult ; Aged ; Aged, 80 and over ; Computer Simulation ; CpG Islands/genetics ; Diabetes Mellitus, Type 2/metabolism ; Epigenesis, Genetic/physiology ; Epigenomics/methods ; Female ; Gene Expression Profiling/methods ; Gene Expression Regulation/genetics ; Genome-Wide Association Study/methods ; Homeostasis/genetics ; Humans ; Male ; Metabolic Networks and Pathways/genetics ; Middle Aged ; Obesity/metabolism ; Polymorphism, Single Nucleotide/physiology ; Young Adult

المؤلفون: Hidalgo B; Department of Biostatistics, Section on Statistical Genetics, University of Alabama at Birmingham, Birmingham, AL., Irvin MR, Sha J, Zhi D, Aslibekyan S, Absher D, Tiwari HK, Kabagambe EK, Ordovas JM, Arnett DK

المصدر: Diabetes [Diabetes] 2014 Feb; Vol. 63 (2), pp. 801-7. Date of Electronic Publication: 2013 Oct 29.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Diabetes Association Country of Publication: United States NLM ID: 0372763 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1939-327X (Electronic) Linking ISSN: 00121797 NLM ISO Abbreviation: Diabetes Subsets: MEDLINE

مواضيع طبية MeSH: Epigenomics*, Blood Glucose/*metabolism , Epigenesis, Genetic/*physiology , Homeostasis/*physiology , Insulin/*blood , Insulin Resistance/*physiology, Diabetes Mellitus, Type 2/metabolism ; Gene Expression Regulation/physiology ; Humans ; Reproducibility of Results ; Risk Factors ; Transcriptome

المؤلفون: DiCorpo, Daniel, Gaynor, Sheila M, Russell, Emily M, Westerman, Kenneth E, Raffield, Laura M, Majarian, Timothy D, Wu, Peitao, Sarnowski, Chloé, Highland, Heather M, Jackson, Anne, Hasbani, Natalie R, de Vries, Paul S, Brody, Jennifer A, Hidalgo, Bertha, Guo, Xiuqing, Perry, James A, O’Connell, Jeffrey R, Lent, Samantha, Montasser, May E, Cade, Brian E, Jain, Deepti, Wang, Heming, D’Oliveira Albanus, Ricardo, Varshney, Arushi, Yanek, Lisa R, Lange, Leslie, Palmer, Nicholette D, Almeida, Marcio, Peralta, Juan M, Aslibekyan, Stella, Baldridge, Abigail S, Bertoni, Alain G, Bielak, Lawrence F, Chen, Chung-Shiuan, Chen, Yii-Der Ida, Choi, Won Jung, Goodarzi, Mark O, Floyd, James S, Irvin, Marguerite R, Kalyani, Rita R, Kelly, Tanika N, Lee, Seonwook, Liu, Ching-Ti, Loesch, Douglas, Manson, JoAnn E, Minster, Ryan L, Naseri, Take, Pankow, James S, Rasmussen-Torvik, Laura J, Reiner, Alexander P, Reupena, Muagututi’a Sefuiva, Selvin, Elizabeth, Smith, Jennifer A, Weeks, Daniel E, Xu, Huichun, Yao, Jie, Zhao, Wei, Parker, Stephen, Alonso, Alvaro, Arnett, Donna K, Blangero, John, Boerwinkle, Eric, Correa, Adolfo, Cupples, L Adrienne, Curran, Joanne E, Duggirala, Ravindranath, He, Jiang, Heckbert, Susan R, Kardia, Sharon LR, Kim, Ryan W, Kooperberg, Charles, Liu, Simin, Mathias, Rasika A, McGarvey, Stephen T, Mitchell, Braxton D, Morrison, Alanna C, Peyser, Patricia A, Psaty, Bruce M, Redline, Susan, Shuldiner, Alan R, Taylor, Kent D, Vasan, Ramachandran S, Viaud-Martinez, Karine A, Florez, Jose C, Wilson, James G, Sladek, Robert, Rich, Stephen S, Rotter, Jerome I, Lin, Xihong, Dupuis, Josée, Meigs, James B, Wessel, Jennifer, Manning, Alisa K

المصدر: Communications Biology. 5(1)

مصطلحات موضوعية: Biological Sciences, Genetics, Human Genome, Biotechnology, Diabetes, 2.1 Biological and endogenous factors, Aetiology, Metabolic and endocrine, Good Health and Well Being, Diabetes Mellitus, Type 2, Fasting, Glucose, Humans, Insulin, National Heart, Lung, and Blood Institute (U.S.), Nerve Tissue Proteins, Polymorphism, Single Nucleotide, Precision Medicine, Receptors, Immunologic, United States, Biological sciences, Biomedical and clinical sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/4rg100w1

المؤلفون: Wessel, Jennifer, Chu, Audrey Y, Willems, Sara M, Wang, Shuai, Yaghootkar, Hanieh, Brody, Jennifer A, Dauriz, Marco, Hivert, Marie-France, Raghavan, Sridharan, Lipovich, Leonard, Hidalgo, Bertha, Fox, Keolu, Huffman, Jennifer E, An, Ping, Lu, Yingchang, Rasmussen-Torvik, Laura J, Grarup, Niels, Ehm, Margaret G, Li, Li, Baldridge, Abigail S, Stančáková, Alena, Abrol, Ravinder, Besse, Céline, Boland, Anne, Bork-Jensen, Jette, Fornage, Myriam, Freitag, Daniel F, Garcia, Melissa E, Guo, Xiuqing, Hara, Kazuo, Isaacs, Aaron, Jakobsdottir, Johanna, Lange, Leslie A, Layton, Jill C, Li, Man, Hua Zhao, Jing, Meidtner, Karina, Morrison, Alanna C, Nalls, Mike A, Peters, Marjolein J, Sabater-Lleal, Maria, Schurmann, Claudia, Silveira, Angela, Smith, Albert V, Southam, Lorraine, Stoiber, Marcus H, Strawbridge, Rona J, Taylor, Kent D, Varga, Tibor V, Allin, Kristine H, Amin, Najaf, Aponte, Jennifer L, Aung, Tin, Barbieri, Caterina, Bihlmeyer, Nathan A, Boehnke, Michael, Bombieri, Cristina, Bowden, Donald W, Burns, Sean M, Chen, Yuning, Chen, Yii-DerI, Cheng, Ching-Yu, Correa, Adolfo, Czajkowski, Jacek, Dehghan, Abbas, Ehret, Georg B, Eiriksdottir, Gudny, Escher, Stefan A, Farmaki, Aliki-Eleni, Frånberg, Mattias, Gambaro, Giovanni, Giulianini, Franco, Goddard, William A, Goel, Anuj, Gottesman, Omri, Grove, Megan L, Gustafsson, Stefan, Hai, Yang, Hallmans, Göran, Heo, Jiyoung, Hoffmann, Per, Ikram, Mohammad K, Jensen, Richard A, Jørgensen, Marit E, Jørgensen, Torben, Karaleftheri, Maria, Khor, Chiea C, Kirkpatrick, Andrea, Kraja, Aldi T, Kuusisto, Johanna, Lange, Ethan M, Lee, IT, Lee, Wen-Jane, Leong, Aaron, Liao, Jiemin, Liu, Chunyu, Liu, Yongmei, Lindgren, Cecilia M, Linneberg, Allan, Malerba, Giovanni

المصدر: Nature communications. 6(1)

مصطلحات موضوعية: EPIC-InterAct Consortium, Humans, Diabetes Mellitus, Type 2, Genetic Predisposition to Disease, Insulin, Glucose-6-Phosphatase, Blood Glucose, Oligonucleotide Array Sequence Analysis, Fasting, Polymorphism, Single Nucleotide, African Continental Ancestry Group, European Continental Ancestry Group, Genetic Variation, Genetic Loci, Genetic Association Studies, Mutation Rate, Exome, Glucagon-Like Peptide-1 Receptor, Diabetes Mellitus, Type 2, Polymorphism, Single Nucleotide, Diabetes, Genetics, Nutrition, Clinical Research, Prevention, Human Genome, 2.1 Biological and endogenous factors, Metabolic and Endocrine

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/8rr9g67v

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