نتائج البحث - "Markus A. Rüegg"

1

دورية أكاديمية

Raptor levels are critical for β-cell adaptation to a high-fat diet in male mice

المؤلفون: Manuel Blandino-Rosano, Ruy Andrade Louzada, Joao Pedro Werneck-De-Castro, Camila Lubaczeuski, Joana Almaça, Markus A. Rüegg, Michael N. Hall, Gil Leibowitz, Ernesto Bernal-Mizrachi

المصدر: Molecular Metabolism, Vol 75, Iss , Pp 101769- (2023)

مصطلحات موضوعية: Islet, Beta-cell, Raptor, High-fat diet, PDX1, FOXA2, Internal medicine, RC31-1245

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2212877823001035; https://doaj.org/toc/2212-8778

URL الوصول: https://doaj.org/article/492f65d1d70946308c8773653d0f3eef

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2

Distinct and additive effects of calorie restriction and rapamycin in aging skeletal muscle

المؤلفون: Christoph Handschin, Aurel B. Leuchtmann, Mihaela Zavolan, Julien Delezie, Anastasiya Börsch, Regula Furrer, Dominik Burri, Daniel J. Ham, Nitish Mittal, Lionel A. Tintignac, Thürkauf M, Shuo Lin, Michael Sinnreich, Alexander S. Ham, Markus A. Rüegg, Kathrin Chojnowska

مصطلحات موضوعية: Sirolimus, Aging, medicine.medical_specialty, Muscle loss, Calorie restriction, Life quality, Skeletal muscle, mTORC1, Mechanistic Target of Rapamycin Complex 1, Biology, Mice, Endocrinology, medicine.anatomical_structure, Internal medicine, Gene expression, medicine, Animals, Muscle, Skeletal, Caloric Restriction

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45a6cb405efb16d53c344bb20a9ee96f

3

Loss of mTORC1 signaling alters pancreatic α cell mass and impairs glucagon secretion

المؤلفون: George K. Gittes, Ernesto Bernal-Mizrachi, Nadejda Bozadjieva, Xiao Qing Dai, Patrick E. MacDonald, Markus A. Rüegg, Jennifer Gimeno, Manuel Blandino-Rosano, Danielle Dean, Michael N. Hall, Jennifer Chase, Kelsey Cummings, Alvin C. Powers

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b66ee723ffb88fae05554dee11bc0fa
https://europepmc.org/articles/PMC5707167/

4

Acute mTOR inhibition induces insulin resistance and alters substrate utilization in vivo

المؤلفون: Lykke Sylow, Anne-Julie Oxboll, David E. James, Andreas Børsting Jordy, Daniel J. Fazakerley, Markus A. Rüegg, Kristen C. Thomas, James R. Krycer, Thomas E. Jensen, Guang Yang, Maximilian Kleinert, Peter Schjerling, Erik A. Richter, Bente Kiens

المساهمون: Fazakerley, Daniel [0000-0001-8241-2903], Apollo - University of Cambridge Repository

المصدر: Molecular Metabolism

مصطلحات موضوعية: medicine.medical_specialty, biology, Glucose uptake, Skeletal muscle, Cell Biology, mTORC1, medicine.disease, mTORC2, Rictor, Metabolism, Endocrinology, medicine.anatomical_structure, Insulin resistance, Internal medicine, medicine, biology.protein, Myocyte, Glucose homeostasis, Original Article, Glycolysis, Molecular Biology, GLUT4

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a48c18f07257a4e98eef63060cd7507f

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5

Loss of mTORC1 signalling impairs β-cell homeostasis and insulin processing

المؤلفون: Joao Pedro Werneck-de-Castro, Ernesto Bernal-Mizrachi, Nadejda Bozadjieva, Nahum Sonenberg, Masayuki Hatanaka, Raghavendra G. Mirmira, Margarita Jimenez-Palomares, Rebecca Barbaresso, Markus A. Rüegg, Ming Liu, Michael N. Hall, Manuel Blandino-Rosano

المصدر: Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Nature Communications

مصطلحات موضوعية: Blood Glucose, 0301 basic medicine, medicine.medical_specialty, Transgene, Science, General Physics and Astronomy, Mice, Transgenic, P70-S6 Kinase 1, mTORC1, Mechanistic Target of Rapamycin Complex 1, Article, General Biochemistry, Genetics and Molecular Biology, Diabetes Mellitus, Experimental, Mice, 03 medical and health sciences, 0302 clinical medicine, Insulin-Secreting Cells, Internal medicine, Autophagy, medicine, Animals, Homeostasis, Humans, Insulin, Eukaryotic Initiation Factors, Sirolimus, Multidisciplinary, biology, Chemistry, Ribosomal Protein S6 Kinases, Carboxypeptidase H, Regulatory-Associated Protein of mTOR, General Chemistry, Metabolism disorder, Cell biology, Eukaryotic Initiation Factor-4E, 030104 developmental biology, Endocrinology, Carboxypeptidase E, biology.protein, biological phenomena, cell phenomena, and immunity, 030217 neurology & neurosurgery, Insulin processing

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f985747ab1b850db3dec677fea71610
https://edoc.unibas.ch/55701/

6

Report on the Myomatrix Conference April 22–24, 2012, University of Nevada, Reno, Nevada, USA

المؤلفون: Rachelle H. Crosbie-Watson, Kanneboyina Nagaraju, Sólveig Thorsteinsdóttir, Janice A. Dominov, Gabrielle Kardon, Markus A. Rüegg, Michelle L. Matter, Susan C. Brown, Carsten G. Bönnemann, Dean J. Burkin, Denis C. Guttridge, Anne Rutkowski, Mahasweta Girgenrath

المصدر: Neuromuscular Disorders. 23:188-191

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8d55b36f087904d00c1f1148c1dfed1
https://doi.org/10.1016/j.nmd.2012.06.353

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7

Alterations to mTORC1 signaling in the skeletal muscle differentially affect whole-body metabolism

المؤلفون: Markus A. Rüegg, Maitea Guridi, Shuo Lin, Denis Falcetta, Lionel A. Tintignac, Barbara Kupr, Klaas Romanino

المصدر: Skeletal Muscle

مصطلحات موضوعية: Blood Glucose, 0301 basic medicine, Time Factors, Myopathy, mTORC1, Tuberous Sclerosis Complex 1 Protein, chemistry.chemical_compound, 0302 clinical medicine, Insulin, Orthopedics and Sports Medicine, Mice, Knockout, Glycogen, TOR Serine-Threonine Kinases, Diabetes, Age Factors, Up-Regulation, Raptor, Cell biology, Phenotype, medicine.anatomical_structure, Body Composition, mTOR, Muscle, medicine.symptom, Signal Transduction, medicine.medical_specialty, Genotype, 030209 endocrinology & metabolism, Mechanistic Target of Rapamycin Complex 1, Biology, Diet, High-Fat, Histone Deacetylases, 03 medical and health sciences, Insulin resistance, Muscular Diseases, Thinness, Downregulation and upregulation, Internal medicine, medicine, Animals, Obesity, Muscle, Skeletal, Molecular Biology, Protein kinase B, Adaptor Proteins, Signal Transducing, Tumor Suppressor Proteins, Research, Glucose transporter, Skeletal muscle, Regulatory-Associated Protein of mTOR, Cell Biology, medicine.disease, TSC1, Metabolism, 030104 developmental biology, Endocrinology, chemistry, Multiprotein Complexes, Insulin Resistance, Energy Metabolism, Proto-Oncogene Proteins c-akt, Biomarkers

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::056e2a48a45b6e140e10b9caacb7056f
https://edoc.unibas.ch/42551/

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Cardiac mTOR complex 2 preserves ventricular function in pressure-overload hypertrophy

المؤلفون: Pankaj S. Shende, Thierry Pedrazzini, Beat A. Kaufmann, Philippe Heim, Michael N. Hall, Markus A. Rüegg, Marijke Brink, Corinne Berthonneche, Laura Pentassuglia, Lifen Xu, Christian Morandi, Sonia Lebboukh

المصدر: Cardiovascular Research

مصطلحات موضوعية: Male, 0301 basic medicine, medicine.medical_specialty, Physiology, Apoptosis, Cardiomegaly, Mechanistic Target of Rapamycin Complex 2, mTORC1, Biology, mTORC2, Muscle hypertrophy, Mice, 03 medical and health sciences, Fibrosis, Physiology (medical), Internal medicine, medicine, Animals, Ventricular Function, Phosphorylation, Protein Kinase C, PI3K/AKT/mTOR pathway, Protein kinase C, Pressure overload, Myocardium, TOR Serine-Threonine Kinases, digestive, oral, and skin physiology, Phosphoproteins, medicine.disease, Mice, Inbred C57BL, Rapamycin-Insensitive Companion of mTOR Protein, 030104 developmental biology, Endocrinology, Multiprotein Complexes, Heart failure, Carrier Proteins, Cardiology and Cardiovascular Medicine, Proto-Oncogene Proteins c-akt, Signal Transduction

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::156b49d428020934c9059a2575ea02c3
https://edoc.unibas.ch/40862/

9

Hepatic mTORC2 activates glycolysis and lipogenesis through Akt, glucokinase, and SREBP1c

المؤلفون: Markus H. Heim, Pazit Polak, Charles Betz, Marion Cornu, Michael N. Hall, Luigi Terracciano, Asami Hagiwara, Francesca Trapani, Nadine Cybulski, Markus A. Rüegg

المصدر: Cell Metabolism
Cell metabolism

مصطلحات موضوعية: Male, Physiology, FOXO1, mTORC1, mTORC2, Glycogen Synthase Kinase 3, Mice, 0302 clinical medicine, Glucokinase, Homeostasis, Insulin, Glycolysis, Phosphorylation, Mice, Knockout, 0303 health sciences, Forkhead Box Protein O1, TOR Serine-Threonine Kinases, Forkhead Transcription Factors, 3. Good health, Liver, 030220 oncology & carcinogenesis, Lipogenesis, Sterol Regulatory Element Binding Protein 1, Signal Transduction, medicine.medical_specialty, Mechanistic Target of Rapamycin Complex 2, Mechanistic Target of Rapamycin Complex 1, Biology, 03 medical and health sciences, Hyperinsulinism, Internal medicine, Glucose Intolerance, medicine, Animals, Molecular Biology, Protein kinase B, 030304 developmental biology, Glycogen Synthase Kinase 3 beta, Gluconeogenesis, Proteins, Cell Biology, Lipid Metabolism, Glucose, Endocrinology, Hyperglycemia, Multiprotein Complexes, Hepatocytes, Trans-Activators, Proto-Oncogene Proteins c-akt, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::280711189f4fb28a4f64e7705f1f8603

10

Muscle-selective synaptic disassembly and reorganization in MuSK antibody positive MG mice

المؤلفون: Filippo Oliveri, Anna Rostedt Punga, Shuo Lin, Markus A. Rüegg, Sarina Meinen

المصدر: Experimental Neurology; Vol 230
Experimental Neurology
Experimental neurology

مصطلحات موضوعية: medicine.medical_specialty, Blotting, Western, Neuromuscular Junction, Enzyme-Linked Immunosorbent Assay, Biology, Neuromuscular junction, Masseter muscle, Mice, 03 medical and health sciences, 0302 clinical medicine, Atrophy, Developmental Neuroscience, Postsynaptic potential, Internal medicine, medicine, Animals, Receptors, Cholinergic, Muscle, Skeletal, Autoantibodies, 030304 developmental biology, Acetylcholine receptor, Denervation, 0303 health sciences, Reverse Transcriptase Polymerase Chain Reaction, medicine.disease, Myasthenia gravis, Muscle atrophy, Myasthenia Gravis, Autoimmune, Experimental, Muscular Atrophy, Endocrinology, medicine.anatomical_structure, Neurology, Female, medicine.symptom, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96e97e2e2531c5f8a73a0851d8ff2da4
https://doi.org/10.1016/j.expneurol.2011.04.018

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