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المؤلفون: Erik Sjögren, James Butler, Vidula Kolhatkar, Xavier Pepin, Lynne S. Taylor, Andrew Babiskin, Sandra Suarez-Sharp, Paul Seo, Jennifer B. Dressman, Christer Tannergren, André Dallmann, Xinyuan Zhang, Poonam Delvadia, Edmund Kostewicz, Yang Zhao, Amitava Mitra, Filippos Kesisoglou, Mirko Koziolek, Neil Parrott
المصدر: Journal of Pharmaceutical Sciences. 110:567-583
مصطلحات موضوعية: Research Report, Physiologically based pharmacokinetic modelling, Process management, Computer science, Best practice, media_common.quotation_subject, Administration, Oral, Pharmaceutical Science, 02 engineering and technology, Models, Biological, 030226 pharmacology & pharmacy, Session (web analytics), Biopharmaceutics, 03 medical and health sciences, 0302 clinical medicine, IVIVC, Drug Development, Quality (business), media_common, 021001 nanoscience & nanotechnology, Biopharmaceutical, Model parameter, Intestinal Absorption, Solubility, 0210 nano-technology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4d0f759414a16121ec56c04e1405fb4
https://doi.org/10.1016/j.xphs.2020.09.021 -
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المؤلفون: Camilla Tibaldi, Francesca Truzzi, Eros D′Amen, Giovanni Dinelli, Yanxin Zhang
المساهمون: Truzzi F., Tibaldi C., Zhang Y., Dinelli G., D'Amen E.
المصدر: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 5514, p 5514 (2021)مصطلحات موضوعية: Flavonols, Bioavailability, LogP, Review, Coumaric Acid, 030226 pharmacology & pharmacy, Ferulic acid, chemistry.chemical_compound, 0302 clinical medicine, Stilbenes, Food science, Biology (General), Spectroscopy, media_common, Chemistry, food and beverages, General Medicine, Isoflavone, Computer Science Applications, 030220 oncology & carcinogenesis, Biological Product, Quercetin, Flavonol, Ellagic acid, Human, Drug, Polyphenol, Coumaric Acids, QH301-705.5, media_common.quotation_subject, Biological Availability, Catalysis, Permeability, Inorganic Chemistry, 03 medical and health sciences, Nutraceutical, Chlorogenic acid, Animals, Humans, Physical and Theoretical Chemistry, Molecular Biology, QD1-999, Flavone, Biological Products, Animal, Organic Chemistry, Polyphenols, Flavones, Isoflavones, Metabolism, Intestinal Absorption, Solubility, Biopharmaceutical classification system, Stilbene, Tannins
وصف الملف: ELETTRONICO
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1646f5f82ff65362c019e1d4dbd203a
http://hdl.handle.net/11585/858441 -
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المؤلفون: Panos Macheras, Pavlos Chryssafidis
المصدر: Pharmaceutical research. 37(10)
مصطلحات موضوعية: Drug, Absorption time, Colon, media_common.quotation_subject, Flurbiprofen, Cmax, Pharmaceutical Science, Thermodynamics, Administration, Oral, 02 engineering and technology, 030226 pharmacology & pharmacy, Models, Biological, Permeability, Biopharmaceutics, 03 medical and health sciences, 0302 clinical medicine, IVIVC, Pharmacokinetics, Intestine, Small, medicine, Humans, Pharmacology (medical), Computer Simulation, Gastrointestinal Transit, media_common, Pharmacology, Chemistry, Organic Chemistry, Reproducibility of Results, 021001 nanoscience & nanotechnology, Ibuprofen, Gastrointestinal Tract, Biopharmaceutical, Intestinal Absorption, Solubility, Molecular Medicine, 0210 nano-technology, Algorithms, Biotechnology, medicine.drug
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المؤلفون: Yukihiro Nomura, Mai Shimizu, Toshio Taniguchi, Tatsuki Fukami, Miki Nakajima
المصدر: Journal of pharmaceutical sciences. 109(5)
مصطلحات موضوعية: Absorption (pharmacology), Cell Membrane Permeability, Membrane permeability, Pharmaceutical Science, 02 engineering and technology, 030226 pharmacology & pharmacy, 03 medical and health sciences, 0302 clinical medicine, Dogs, Aqueous solubility, Animals, Humans, Prodrugs, Solubility, Active metabolite, Improved solubility, Chemistry, Prodrug, 021001 nanoscience & nanotechnology, Intestines, Biopharmaceutical, Biochemistry, Intestinal Absorption, Caco-2 Cells, 0210 nano-technology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d9545bf863502bcff408b11e69729fb
https://pubmed.ncbi.nlm.nih.gov/32027923 -
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المؤلفون: Chara Litou, Karl J. Box, David B. Turner, Nikunjkumar Patel, Jennifer B. Dressman, Edmund Kostewicz, Martin Kuentz
المساهمون: Publica
المصدر: European Journal of Pharmaceutical Sciences
مصطلحات موضوعية: Adult, Physiologically based pharmacokinetic modelling, Adolescent, In silico, Chemistry, Pharmaceutical, Pharmaceutical Science, 02 engineering and technology, 030226 pharmacology & pharmacy, Models, Biological, 03 medical and health sciences, Surface-Active Agents, Young Adult, 0302 clinical medicine, Pharmacokinetics, In vivo, medicine, Humans, Computer Simulation, ddc:610, Particle Size, Aprepitant, Active ingredient, Cross-Over Studies, Chemistry, Fasting, 021001 nanoscience & nanotechnology, Bioavailability, Gastrointestinal Tract, Biopharmaceutical, Intestinal Absorption, Solubility, Nanoparticles, Biochemical engineering, 0210 nano-technology, medicine.drug
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68d06ca46b1d63a704192ba46b96039a
http://publikationen.ub.uni-frankfurt.de/files/50918/Aprepitant_research_paper_submission_version.pdf -
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المؤلفون: Claire Mackie, Marcus E. Brewster, Jan Bevernage, Erik Mannaert, Sandy Van Hemelryck, Achiel Van Peer, An Van Den Bergh
المصدر: Molecular Pharmaceutics. 15:2633-2645
مصطلحات موضوعية: Decision Making, Administration, Oral, Pharmaceutical Science, 02 engineering and technology, Pharmaceutical formulation, Pharmacology, Models, Biological, 030226 pharmacology & pharmacy, Mice, 03 medical and health sciences, Dogs, 0302 clinical medicine, Drug Development, Species Specificity, Drug Discovery, Retrospective analysis, Animals, Humans, Medicine, Pharmacokinetics, Retrospective Studies, Active ingredient, Dose-Response Relationship, Drug, business.industry, Decision Trees, 021001 nanoscience & nanotechnology, Predictive value, Rats, Bioavailability, Clinical formulation, Biopharmaceutical, Dose number, Intestinal Absorption, Solubility, Models, Animal, Molecular Medicine, 0210 nano-technology, business
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المصدر: Journal of Pharmaceutical Sciences. 107:307-316
مصطلحات موضوعية: In vitro dissolution, Chemistry, Pharmaceutical, Pharmaceutical Science, 02 engineering and technology, Pharmacology, Models, Biological, 030226 pharmacology & pharmacy, Permeability, 03 medical and health sciences, 0302 clinical medicine, In vivo, medicine, Humans, Computer Simulation, Raloxifene, Dissolution testing, Dissolution, Chemistry, 021001 nanoscience & nanotechnology, Gastrointestinal Tract, Drug Liberation, Ketoconazole, Biopharmaceutical, Intestinal Absorption, Solubility, Raloxifene Hydrochloride, In vitro system, 0210 nano-technology, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::498fb14f76d46a5cfa97857281a1f90f
https://doi.org/10.1016/j.xphs.2017.09.002 -
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المؤلفون: Neil Parrott, Martin Kuentz, Philip Kohlmann, Cordula Stillhart
المصدر: The AAPS Journal. 19:1864-1877
مصطلحات موضوعية: Physiologically based pharmacokinetic modelling, Adolescent, In vitro dissolution, Administration, Oral, Pharmaceutical Science, Absorption (skin), Pharmacology, Models, Biological, 030226 pharmacology & pharmacy, 03 medical and health sciences, 0302 clinical medicine, Pharmacokinetics, medicine, Humans, Child, Sensitivity analyses, business.industry, Infant, Newborn, Infant, Pediatric age, Carbamazepine, Biopharmaceutical, Intestinal Absorption, Solubility, Child, Preschool, 030220 oncology & carcinogenesis, business, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4960e8406f743501189e58484b0ef75b
https://doi.org/10.1208/s12248-017-0149-6 -
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المؤلفون: Bhupinder Singh, Rajneet Kaur Khurana, Arvind K. Bansal, Andrea Julie Burrow, O. P. Katare, Kamalinder K. Singh, Sarwar Beg
المصدر: International Journal of Pharmaceutics. 518:289-306
مصطلحات موضوعية: Cell Survival, Xanthones, Biological Availability, Pharmaceutical Science, B200, 02 engineering and technology, 030226 pharmacology & pharmacy, Rats, Sprague-Dawley, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Pharmacokinetics, In vivo, Zeta potential, Animals, Humans, Particle Size, Rats, Wistar, Mangiferin, Phospholipids, Drug Carriers, Chromatography, Chemistry, B230, Permeation, 021001 nanoscience & nanotechnology, Nanostructures, Molecular Docking Simulation, Partition coefficient, Drug Liberation, Biopharmaceutical, Intestinal Absorption, Solubility, Particle size, Caco-2 Cells, 0210 nano-technology
وصف الملف: application/pdf
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المؤلفون: Jin Sun, Zhonggui He, Chunnuan Wu, Yan Liu
المصدر: Current Drug Delivery. 13:1004-1020
مصطلحات موضوعية: Quality Control, Drug, media_common.quotation_subject, Pharmaceutical Science, Nanotechnology, 02 engineering and technology, 030226 pharmacology & pharmacy, Intestinal absorption, Surface-Active Agents, 03 medical and health sciences, 0302 clinical medicine, In vivo, Animals, Humans, Dissolution testing, Solubility, Dissolution, media_common, Chemistry, 021001 nanoscience & nanotechnology, Water soluble, Biopharmaceutical, Intestinal Absorption, Pharmaceutical Preparations, Solvents, Biochemical engineering, 0210 nano-technology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e10d37e93f2bf9fce032d87030527ec
https://doi.org/10.2174/1567201813666160104130212
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