المؤلفون: Carlsson G; Department of Surgery, Ostra Sjukhuset, Göteborg, Sweden., Gustavsson B, Frösing R, Odin E, Hafström LO, Spears CP, Larsson PA

المصدر: Biochemical pharmacology [Biochem Pharmacol] 1995 Oct 26; Vol. 50 (9), pp. 1347-51.

نوع المنشور: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

بيانات الدورية: Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print Cited Medium: Print ISSN: 0006-2952 (Print) Linking ISSN: 00062952 NLM ISO Abbreviation: Biochem Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Antimetabolites, Antineoplastic/*pharmacology , Antineoplastic Combined Chemotherapy Protocols/*pharmacology , Colonic Neoplasms/*drug therapy , Fluorouracil/*pharmacology , Leucovorin/*pharmacology , Liver Neoplasms, Experimental/*drug therapy, Animals ; Antimetabolites, Antineoplastic/administration & dosage ; Antimetabolites, Antineoplastic/toxicity ; Cell Division/drug effects ; Colonic Neoplasms/enzymology ; Colonic Neoplasms/pathology ; Disease Models, Animal ; Enzyme Inhibitors/pharmacology ; Fluorouracil/administration & dosage ; Fluorouracil/toxicity ; Leucovorin/administration & dosage ; Leucovorin/toxicity ; Liver Neoplasms, Experimental/enzymology ; Liver Neoplasms, Experimental/pathology ; Male ; Neoplasm Transplantation ; Random Allocation ; Rats ; Rats, Wistar ; Stereoisomerism ; Thymidylate Synthase/antagonists & inhibitors ; Thymidylate Synthase/metabolism

المؤلفون: Spears CP; University of Southern California Comprehensive Cancer Center, Los Angeles 90033., Gustavsson BG, Frösing R

المصدر: Investigational new drugs [Invest New Drugs] 1989 Apr; Vol. 7 (1), pp. 27-36.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

بيانات الدورية: Publisher: Springer Country of Publication: United States NLM ID: 8309330 Publication Model: Print Cited Medium: Print ISSN: 0167-6997 (Print) Linking ISSN: 01676997 NLM ISO Abbreviation: Invest New Drugs Subsets: MEDLINE

مواضيع طبية MeSH: Fluorouracil/*pharmacokinetics , Leucovorin/*pharmacology, Aged ; Biotransformation ; Colonic Neoplasms/metabolism ; Cytosol/metabolism ; Drug Interactions ; Female ; Fluorodeoxyuridylate/metabolism ; Fluorouracil/administration & dosage ; Fluorouracil/metabolism ; Humans ; Lacticaseibacillus casei/metabolism ; Male ; Middle Aged ; Thymidylate Synthase/metabolism

المؤلفون: Gustavsson BG; Ostra sjukhuset, University of Gothenburg, Sweden., Carlsson G, Frösing R, Spears CP

المصدر: Advances in experimental medicine and biology [Adv Exp Med Biol] 1988; Vol. 244, pp. 219-24.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 0121103 Publication Model: Print Cited Medium: Print ISSN: 0065-2598 (Print) Linking ISSN: 00652598 NLM ISO Abbreviation: Adv Exp Med Biol Subsets: MEDLINE

مواضيع طبية MeSH: Bone Marrow/*metabolism , Colonic Neoplasms/*metabolism , Fluorouracil/*pharmacokinetics , Leucovorin/*pharmacology , Liver/*metabolism , Pancreatic Neoplasms/*metabolism , Rectal Neoplasms/*metabolism , Stomach Neoplasms/*metabolism , Thymidylate Synthase/*metabolism, Adenocarcinoma/drug therapy ; Animals ; Colonic Neoplasms/drug therapy ; Deoxyuracil Nucleotides/metabolism ; Fluorodeoxyuridylate/metabolism ; Fluorouracil/therapeutic use ; Humans ; Intestinal Mucosa/metabolism ; Leucovorin/therapeutic use ; Rats ; Rats, Inbred Strains

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