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المؤلفون: Ferrari, E., Gu, C., Niranjan, D., Restani, L., Rasetti-Escargueil, C., Obara, I., Geranton, S. M., Arsenault, J., Goetze, T. A., Harper, C. B., Nguyen, T. H., Maywood, E., O'Brien, J., Schiavo, G., Wheeler, D. W., Meunier, F. A., Hastings, M., Edwardson, J. M., Sesardic, D., Caleo, M., Hunt, S. P., Davletov, B.
المساهمون: MRC Laboratory of Molecular Biology [Cambridge, UK] (LMB), University of Cambridge [UK] (CAM)-Medical Research Council, University of Lincoln, Istituto di Neuroscienze, National Institute for Biological Standards and Control (NIBSC), Medicines and Healthcare Products Regulatory Agency (MHRA), School of Medicine, Pharmacy and Health, Durham University, Department of Cell and Developmental Biology [London, UK], University College of London [London] (UCL), Department of Pharmacology - University of Cambridge, University of Cambridge [UK] (CAM), Queensland Brain Institute, University of Queensland [Brisbane], Department of Biomedical Sciences [Sheffield, UK], University of Sheffield [Sheffield], Addenbrooke's Hospital, Cambridge University NHS Trust, Cambridge University Hospitals - NHS (CUH), This study was supported by the MRC grant U10578791 and Wellcome Trust Grant No. 089125/Z/09/Z., We thank David Menon and Peter McNaughton for helpful discussions. We thank Richard Berks, Claire Knox, and Angela Middleton for their help with the biological tests., Medical Research Council-University of Cambridge [UK] (CAM)
المصدر: Bioconjugate Chemistry
Bioconjugate Chemistry, American Chemical Society, 2013, 24 (10), pp.1750-1759. ⟨10.1021/bc4003103⟩
Bioconjugate chemistry, 2013, Vol.24(10), pp.1750-1759 [Peer Reviewed Journal]مصطلحات موضوعية: Male, Models, Molecular, Pain Threshold, MESH: Tetanus Toxin / administration & dosage, MESH: Tetanus Toxin / metabolism, MESH: Rats, Recombinant Fusion Proteins, [SDV]Life Sciences [q-bio], MESH: Mice, Inbred BALB C, Neurophysiology, MESH: Botulinum Toxins, Type A / metabolism, Peptides and proteins, MESH: Recombinant Fusion Proteins / metabolism, Article, Mice, Tetanus Toxin, MESH: Pain Threshold / drug effects, MESH: Mice, Inbred C57BL, MESH: Recombinant Fusion Proteins / administration & dosage, Clostridium tetani, MESH: Botulinum Toxins, Type A / administration & dosage, Clostridium botulinum, Animals, Toxins, MESH: Animals, Botulinum Toxins, Type A, MESH: Mice, MESH: Brain / drug effects, Cells, Cultured, Neurons, Mice, Inbred BALB C, MESH: Neurons / cytology, Brain, MESH: Neurons / drug effects, [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology, MESH: Male, Rats, Mice, Inbred C57BL, Rodent models, MESH: Clostridium tetani / metabolism, [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology, Central nervous system, MESH: Brain / physiology, MESH: Clostridium botulinum / metabolism, MESH: Models, Molecular, MESH: Cells, Cultured
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